-
1
-
-
84876730349
-
Targeting of NF-kappaB signaling pathway, other signaling pathways and epigenetics in therapy of multiple myeloma
-
COI: 1:CAS:528:DC%2BC3sXmsVGls7Y%3D, PID: 2353494
-
Fuchs O. Targeting of NF-kappaB signaling pathway, other signaling pathways and epigenetics in therapy of multiple myeloma. Cardiovasc Hematol Disord Drug Targets, 2013,13(1):16–34
-
(2013)
Cardiovasc Hematol Disord Drug Targets
, vol.13
, Issue.1
, pp. 16-34
-
-
Fuchs, O.1
-
2
-
-
0034084163
-
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
-
COI: 1:CAS:528:DC%2BD3cXjs1Gmtro%3D, PID: 1083707
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol, 2000,18:621–663
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
3
-
-
84901684523
-
NF-kappaB pathways in hematological malignancies
-
COI: 1:CAS:528:DC%2BC2cXotF2gtQ%3D%3D, PID: 2441930
-
Gasparini C, Celeghini C, Monasta L, et al. NF-kappaB pathways in hematological malignancies. Cell Mol Life Sci, 2014,71(11):2083–2102
-
(2014)
Cell Mol Life Sci
, vol.71
, Issue.11
, pp. 2083-2102
-
-
Gasparini, C.1
Celeghini, C.2
Monasta, L.3
-
4
-
-
47149099552
-
NF-kappaB in the pathogenesis and treatment of multiple myeloma
-
COI: 1:CAS:528:DC%2BD1cXnvFehu74%3D, PID: 1853657
-
Li ZW, Chen H, Campbell RA, et al. NF-kappaB in the pathogenesis and treatment of multiple myeloma. Curr Opin Hematol, 2008,15(4):391–399
-
(2008)
Curr Opin Hematol
, vol.15
, Issue.4
, pp. 391-399
-
-
Li, Z.W.1
Chen, H.2
Campbell, R.A.3
-
5
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
-
COI: 1:CAS:528:DC%2BD2sXps1art74%3D, PID: 1769280
-
Annunziata CM, Davis RE, Demchenko Y, et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell, 2007,12(2):115–130
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
-
6
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
-
COI: 1:CAS:528:DC%2BD2sXps1art78%3D, PID: 1769280
-
Keats JJ, Fonseca R, Chesi M, et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell, 2007,12(2):131–144
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
-
7
-
-
23944514626
-
Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver
-
Smolinski AT, Pestka JJ. Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver. J Inflamm (Lond), 2005,2:6
-
(2005)
J Inflamm (Lond)
, vol.2
, pp. 6
-
-
Smolinski, A.T.1
Pestka, J.J.2
-
8
-
-
48449083208
-
Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells
-
COI: 1:CAS:528:DC%2BD1MXkslWjt7w%3D, PID: 1851922
-
Pajak B, Gajkowska B, Orzechowski A. Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells. Folia Histochem Cytobiol, 2008,46(2):129–135
-
(2008)
Folia Histochem Cytobiol
, vol.46
, Issue.2
, pp. 129-135
-
-
Pajak, B.1
Gajkowska, B.2
Orzechowski, A.3
-
9
-
-
58149355768
-
The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine
-
COI: 1:CAS:528:DC%2BD1cXhsV2it7rF, PID: 1908802
-
Hewamana S, Lin TT, Jenkins C, et al. The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine. Clin Cancer Res, 2008,14(24):8102–8111
-
(2008)
Clin Cancer Res
, vol.14
, Issue.24
, pp. 8102-8111
-
-
Hewamana, S.1
Lin, T.T.2
Jenkins, C.3
-
10
-
-
16844363378
-
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
-
COI: 1:CAS:528:DC%2BD2MXks12ju74%3D, PID: 1568723
-
Guzman ML, Rossi RM, Karnischky L, et al. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood, 2005,105(11):4163–4169
-
(2005)
Blood
, vol.105
, Issue.11
, pp. 4163-4169
-
-
Guzman, M.L.1
Rossi, R.M.2
Karnischky, L.3
-
11
-
-
58449131932
-
Inhibitory effects of parthenolide on the angiogenesis induced by human multiple myeloma cells and the mechanism
-
COI: 1:CAS:528:DC%2BD1cXhtlyrsLr
-
Kong F, Chen Z, Li Q, et al. Inhibitory effects of parthenolide on the angiogenesis induced by human multiple myeloma cells and the mechanism. J Huazhong Univ Sci Technolog [Med Sci], 2008,28(5):525–530
-
(2008)
J Huazhong Univ Sci Technolog [Med Sci]
, vol.28
, Issue.5
, pp. 525-530
-
-
Kong, F.1
Chen, Z.2
Li, Q.3
-
12
-
-
84883233659
-
Parthenolide: from plant shoots to cancer roots
-
COI: 1:CAS:528:DC%2BC3sXptFGjtbw%3D, PID: 2368858
-
Ghantous A, Sinjab A, Herceg Z et al. Parthenolide: from plant shoots to cancer roots. Drug Discov Today, 2013,18(17–18):894–905
-
(2013)
Drug Discov Today
, vol.18
, Issue.17-18
, pp. 894-905
-
-
Ghantous, A.1
Sinjab, A.2
Herceg, Z.3
-
13
-
-
0034879173
-
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase
-
COI: 1:CAS:528:DC%2BD3MXmtV2ku7k%3D, PID: 1151422
-
Kwok BH, Koh B, Ndubuisi MI et al. The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol, 2001,8(8):759–766
-
(2001)
Chem Biol
, vol.8
, Issue.8
, pp. 759-766
-
-
Kwok, B.H.1
Koh, B.2
Ndubuisi, M.I.3
-
14
-
-
7044275192
-
Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells
-
COI: 1:CAS:528:DC%2BD2cXhtVWgs73J, PID: 1525648
-
Zhang S, Lin ZN, Yang CF et al. Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells. Carcinogenesis, 2004,25(11):2191–2199
-
(2004)
Carcinogenesis
, vol.25
, Issue.11
, pp. 2191-2199
-
-
Zhang, S.1
Lin, Z.N.2
Yang, C.F.3
-
15
-
-
39649125467
-
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
-
COI: 1:CAS:528:DC%2BD1cXot1Wg, PID: 1780469
-
Guzman ML, Rossi RM, Neelakantan S, et al. An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells. Blood, 2007,110(13):4427–4435
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4427-4435
-
-
Guzman, M.L.1
Rossi, R.M.2
Neelakantan, S.3
-
16
-
-
78650019223
-
Transcription factor NF-kappaB inhibitors as single therapeutic agents or in combination with classical chemotherapeutic agents for the treatment of hematologic malignancies
-
COI: 1:CAS:528:DC%2BC3cXhsFarurnF, PID: 2059418
-
Fuchs O. Transcription factor NF-kappaB inhibitors as single therapeutic agents or in combination with classical chemotherapeutic agents for the treatment of hematologic malignancies. Curr Mol Pharmacol, 2010,3(3):98–122
-
(2010)
Curr Mol Pharmacol
, vol.3
, Issue.3
, pp. 98-122
-
-
Fuchs, O.1
-
17
-
-
33750443289
-
IkappaB kinase complexes: gateways to NF-kappaB activation and transcription
-
COI: 1:CAS:528:DC%2BD28XhtFekt7bJ, PID: 1707232
-
Scheidereit C. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. Oncogene, 2006,25(51):6685–6705
-
(2006)
Oncogene
, vol.25
, Issue.51
, pp. 6685-6705
-
-
Scheidereit, C.1
-
18
-
-
77955015392
-
Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology
-
COI: 1:CAS:528:DC%2BC3cXpt1Omt74%3D, PID: 2052995
-
Gautheron J, Pescatore A, Fusco F, et al. Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology. Hum Mol Genet, 2010,19(16):3138–3149
-
(2010)
Hum Mol Genet
, vol.19
, Issue.16
, pp. 3138-3149
-
-
Gautheron, J.1
Pescatore, A.2
Fusco, F.3
-
19
-
-
41549113466
-
Antimyeloma effects of a sesquiterpene lactone parthenolide
-
COI: 1:CAS:528:DC%2BD1cXjtleju7s%3D, PID: 1834718
-
Suvannasankha A, Crean CD, Shanmugam R et al. Antimyeloma effects of a sesquiterpene lactone parthenolide. Clin Cancer Res, 2008,14(6):1814–1822
-
(2008)
Clin Cancer Res
, vol.14
, Issue.6
, pp. 1814-1822
-
-
Suvannasankha, A.1
Crean, C.D.2
Shanmugam, R.3
-
20
-
-
79957443436
-
The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma
-
COI: 1:CAS:528:DC%2BC3MXmtl2msb0%3D, PID: 2141782
-
Gunn EJ, Williams JT, Huynh DT, et al. The natural products parthenolide and andrographolide exhibit anti-cancer stem cell activity in multiple myeloma. Leuk Lymphoma, 2011,52(6):1085–1097
-
(2011)
Leuk Lymphoma
, vol.52
, Issue.6
, pp. 1085-1097
-
-
Gunn, E.J.1
Williams, J.T.2
Huynh, D.T.3
-
21
-
-
66449097674
-
Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions
-
COI: 1:CAS:528:DC%2BD1MXjtVyjsLc%3D, PID: 1927616
-
Gopal YN, Chanchorn E, Van Dyke MW. Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions. Mol Cancer Ther, 2009,8(3):552–562
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.3
, pp. 552-562
-
-
Gopal, Y.N.1
Chanchorn, E.2
Van Dyke, M.W.3
-
22
-
-
0037173095
-
TRAF6-deficient mice display hypohidrotic ectodermal dysplasia
-
COI: 1:CAS:528:DC%2BD38XltF2htr0%3D, PID: 1206072
-
Naito A, Yoshida H, Nishioka E, et al. TRAF6-deficient mice display hypohidrotic ectodermal dysplasia. Proc Natl Acad Sci USA, 2002,99(13):8766–8771
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.13
, pp. 8766-8771
-
-
Naito, A.1
Yoshida, H.2
Nishioka, E.3
-
23
-
-
69549116880
-
The E3 ligase TRAF6 regulates Akt ubiquitination and activation
-
COI: 1:CAS:528:DC%2BD1MXhtVersr%2FL, PID: 1971352
-
Yang WL, Wang J, Chan CH, et al. The E3 ligase TRAF6 regulates Akt ubiquitination and activation. Science, 2009,325(5944):1134–1138
-
(2009)
Science
, vol.325
, Issue.5944
, pp. 1134-1138
-
-
Yang, W.L.1
Wang, J.2
Chan, C.H.3
-
24
-
-
33947506493
-
Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation
-
COI: 1:CAS:528:DC%2BD2sXht1Ojsb0%3D, PID: 1713527
-
Lamothe B, Besse A, Campos AD, et al. Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. J Biol Chem, 2007,282(6):4102–4112
-
(2007)
J Biol Chem
, vol.282
, Issue.6
, pp. 4102-4112
-
-
Lamothe, B.1
Besse, A.2
Campos, A.D.3
|