Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model

Toxicology in Vitro

Volumn 22, Issue 3, 2008, Pages 747-759

  Zöller, Nadja Nicole ^a,b   Kippenberger, Stefan ^a   Thaçi, Diamant ^a   Mewes, Karsten ^b   Spiegel, Martina ^b   Sättler, Andrea ^b   Schultz, Maike ^a   Bereiter Hahn, Jürgen ^a   Kaufmann, Roland ^a   Bernd, August ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Phenion GmbH   (Germany)

Author keywords

Atrophy; Glucocorticoid; Inflammation; Irradiation; Skin model; UVB

Indexed keywords

BETAMETHASONE DIPROPIONATE; BETAMETHASONE SODIUM PHOSPHATE; BETAMETHASONE VALERATE; CLOBETASOL PROPIONATE; COLLAGEN TYPE 1; GLUCOCORTICOID; HYDROCORTISONE; HYDROCORTISONE BUTYRATE; INTERLEUKIN 6; INTERLEUKIN 8; METHYLPREDNISOLONE ACEPONATE; MOMETASONE FUROATE; PREDNICARBATE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATROPHY; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFICACY; DRUG INHIBITION; DRUG SAFETY; DRUG SCREENING; EPIDERMIS CELL; EXPERIMENTAL MODEL; FULL THICKNESS SKIN MODEL; HUMAN; HUMAN TISSUE; IN VIVO STUDY; KERATINOCYTE; PRESCHOOL CHILD; ULTRAVIOLET B RADIATION;

ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; BIOLOGICAL MARKERS; CELL PROLIFERATION; CHILD, PRESCHOOL; COLLAGEN; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; GLUCOCORTICOIDS; HUMANS; IN SITU NICK-END LABELING; INTERLEUKIN-6; INTERLEUKIN-8; KERATINOCYTES; OINTMENTS; SKIN; ULTRAVIOLET RAYS;

EID: 40049084368     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.11.022     Document Type: Article

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