-
1
-
-
0033517302
-
The effect of spironolactone on morbidity and mortality in patients with severe heart failure: Randomized Aldactone Evaluation Study Investigators
-
Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure: Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999; 341:709-717.
-
(1999)
N Engl J Med
, vol.341
, pp. 709-717
-
-
Pitt, B.1
Zannad, F.2
Remme, W.J.3
Cody, R.4
Castaigne, A.5
Perez, A.6
Palensky, J.7
Wittes, J.8
-
2
-
-
0037417252
-
Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
-
Pitt B, Remme W, Zannad F, Neaton J, Martinez F, Roniker B, Bittman R, Hurley S, Kleiman J, Gatlin M. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med. 2003;348:1309-1321.
-
(2003)
N Engl J Med
, vol.348
, pp. 1309-1321
-
-
Pitt, B.1
Remme, W.2
Zannad, F.3
Neaton, J.4
Martinez, F.5
Roniker, B.6
Bittman, R.7
Hurley, S.8
Kleiman, J.9
Gatlin, M.10
-
3
-
-
60749110418
-
Aldosterone blockade and left ventricular dysfunction: A systematic review of randomized clinical trials
-
Ezekowitz JA, McAlister FA. Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials. Eur Heart J. 2009;30:469-477.
-
(2009)
Eur Heart J
, vol.30
, pp. 469-477
-
-
Ezekowitz, J.A.1
McAlister, F.A.2
-
4
-
-
65549154913
-
2009 Focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in collaboration with the International Society for Heart and Lung Transplantation
-
Jessup M, Abraham WT, Casey DE, Feldman AM, Francis GS, Ganiats TG, Konstam MA, Mancini DM, Rahko PS, Silver MA, Stevenson LW, Yancy CW. 2009 Focused update: ACCF/AHA guidelines for the diagnosis and management of heart failure in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation. 2009;119: 1977-2016.
-
(2009)
Circulation
, vol.119
, pp. 1977-2016
-
-
Jessup, M.1
Abraham, W.T.2
Casey, D.E.3
Feldman, A.M.4
Francis, G.S.5
Ganiats, T.G.6
Konstam, M.A.7
Mancini, D.M.8
Rahko, P.S.9
Silver, M.A.10
Stevenson, L.W.11
Yancy, C.W.12
-
5
-
-
70350733579
-
Use of aldosterone antagonists in heart failure
-
Albert NM, Yancy CW, Liang L, Zhao X, Hernandez AF, Peterson ED, Cannon CP, Fonarow GC. Use of aldosterone antagonists in heart failure. JAMA. 2009;21:1658-1665.
-
(2009)
JAMA
, vol.21
, pp. 1658-1665
-
-
Albert, N.M.1
Yancy, C.W.2
Liang, L.3
Zhao, X.4
Hernandez, A.F.5
Peterson, E.D.6
Cannon, C.P.7
Fonarow, G.C.8
-
6
-
-
3442886513
-
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
-
Juurlink DN, Mamdani MM, Lee DS, Kopp A, Austin PC, Laupacis A, Redelmeier DA. Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. N Engl J Med. 2004;351:543-551.
-
(2004)
N Engl J Med
, vol.351
, pp. 543-551
-
-
Juurlink, D.N.1
Mamdani, M.M.2
Lee, D.S.3
Kopp, A.4
Austin, P.C.5
Laupacis, A.6
Redelmeier, D.A.7
-
7
-
-
0035818917
-
Aldosterone in congestive heart failure
-
Weber KT. Aldosterone in congestive heart failure. N Engl J Med. 2001;345:1689-1697.
-
(2001)
N Engl J Med
, vol.345
, pp. 1689-1697
-
-
Weber, K.T.1
-
8
-
-
33846963787
-
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity
-
Leopold JA, Dam A, Maron BA, Scribner AW, Liao R, Handy DE, Stanton RC, Pitt B, Loscalzo J. Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. Nat Med. 2007;13:189-197.
-
(2007)
Nat Med
, vol.13
, pp. 189-197
-
-
Leopold, J.A.1
Dam, A.2
Maron, B.A.3
Scribner, A.W.4
Liao, R.5
Handy, D.E.6
Stanton, R.C.7
Pitt, B.8
Loscalzo, J.9
-
9
-
-
65449146439
-
Hypertension and cardiac failure in its various forms
-
Gaddam KK, Verma A, Thompson M, Amin R, Ventura H. Hypertension and cardiac failure in its various forms. Med Clin North Am. 2009;93:665-680.
-
(2009)
Med Clin North Am
, vol.93
, pp. 665-680
-
-
Gaddam, K.K.1
Verma, A.2
Thompson, M.3
Amin, R.4
Ventura, H.5
-
10
-
-
55949112567
-
Serum potassium and clinical outcomes in the Eplerenone Post-Acute Myo-cardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS)
-
Pitt B, Bakris G, Ruilope LM, DiCarlo L, Mukherjee R. Serum potassium and clinical outcomes in the Eplerenone Post-Acute Myo-cardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS). Circulation. 2008;118:1643-1650.
-
(2008)
Circulation
, vol.118
, pp. 1643-1650
-
-
Pitt, B.1
Bakris, G.2
Ruilope, L.M.3
Dicarlo, L.4
Mukherjee, R.5
-
11
-
-
42349101107
-
A comparison of the aldosterone-blocking agents eplerenone and spironolactone
-
Struthers A, Krum H, Williams GH. A comparison of the aldosterone-blocking agents eplerenone and spironolactone. Clin Cardiol. 2008;31:153-158.
-
(2008)
Clin Cardiol.
, vol.31
, pp. 153-158
-
-
Struthers, A.1
Krum, H.2
Williams, G.H.3
-
12
-
-
0033825899
-
Drug-induced hyperkalemia: Old culprits and new offenders
-
Perazella MA. Drug-induced hyperkalemia: old culprits and new offenders. Am J Med. 2000;109:307-314.
-
(2000)
Am J Med
, vol.109
, pp. 307-314
-
-
Perazella, M.A.1
-
14
-
-
24044466543
-
The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure
-
Shah KB, Rao K, Sawyer R, Gottlieb SS. The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure. J Am Coll Cardiol. 2005;46:845-849.
-
(2005)
J Am Coll Cardiol.
, vol.46
, pp. 845-849
-
-
Shah, K.B.1
Rao, K.2
Sawyer, R.3
Gottlieb, S.S.4
-
15
-
-
0037183651
-
Elevated plasma al-dosterone levels despite complete inhibition of the vascular angiotensin-converting enzyme in chronic heart failure
-
Jorde UP, Vittorio T, Katz SD, Colombo PC, Latif F, Le Jemtel TH. Elevated plasma al-dosterone levels despite complete inhibition of the vascular angiotensin-converting enzyme in chronic heart failure. Circulation. 2002;106:1055-1057.
-
(2002)
Circulation
, vol.106
, pp. 1055-1057
-
-
Jorde, U.P.1
Vittorio, T.2
Katz, S.D.3
Colombo, P.C.4
Latif, F.5
Le Jemtel, T.H.6
-
16
-
-
22844437062
-
Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure
-
DOI 10.1016/j.jacc.2005.04.038, PII S073510970501017X
-
Pitt B, White H, Nicolau J, Martinez F, Gheorghiade M, Aschermann M, van Veldhuisen DJ, Zannad F, Krum H, Mukherjee R, Vincent J. Eplerenone reduces mortality 30 days after randomization following acute myocardial infarction in patients with left ventricular systolic dysfunction and heart failure. J Am Coll Cardiol. 2005;46:425-431. (Pubitemid 41040281)
-
(2005)
Journal of the American College of Cardiology
, vol.46
, Issue.3
, pp. 425-431
-
-
Pitt, B.1
White, H.2
Nicolau, J.3
Martinez, F.4
Gheorghiade, M.5
Aschermann, M.6
Van Veldhuisen, D.J.7
Zannad, F.8
Krum, H.9
Mukherjee, R.10
Vincent, J.11
-
17
-
-
62949146402
-
Aldosterone and long-term outcome after myocardial infarction: A substudy of the French nationwide Obser-vatoire sur la Prise en charge hospitaliere, l'Evolution a un an et les caRacteristiques de patients presentant un infArctus du myocarde avec ou sans onde Q (OPERA) study
-
Beygui F, Montalescot G, Vicaut E, Rouanet S, Van Belle E, Baulac C, Degrandsart A, Dallongeville J. Aldosterone and long-term outcome after myocardial infarction: a substudy of the French nationwide Obser-vatoire sur la Prise en charge hospitaliere, l'Evolution a un an et les caRacteristiques de patients presentant un infArctus du myocarde avec ou sans onde Q (OPERA) study. Am Heart J. 2009;157:680-687.
-
(2009)
Am Heart J
, vol.157
, pp. 680-687
-
-
Beygui, F.1
Montalescot, G.2
Vicaut, E.3
Rouanet, S.4
Van Belle, E.5
Baulac, C.6
Degrandsart, A.7
Dallongeville, J.8
-
18
-
-
68849117403
-
The effects of eplerenone on length of stay and total days of heart failure hospitalization after myocardial infarction in patients with left ventricular systolic dysfunction
-
Gheorghiade M, Khan S, Blair JE, Harinstein ME, Krum H, Mukherjee R, Pitt B. The effects of eplerenone on length of stay and total days of heart failure hospitalization after myocardial infarction in patients with left ventricular systolic dysfunction. Am Heart J. 2009;158: 437-443.
-
(2009)
Am Heart J
, vol.158
, pp. 437-443
-
-
Gheorghiade, M.1
Khan, S.2
Blair, J.E.3
Harinstein, M.E.4
Krum, H.5
Mukherjee, R.6
Pitt, B.7
-
19
-
-
0037125404
-
Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure
-
Cicoira M, Zanolla L, Rossi A, Golia G, Franceschini L, Brighetti G, Marino P, Zardini P. Long-term, dose-dependent effects of spironolactone on left ventricular function and exercise tolerance in patients with chronic heart failure. J Am Coll Cardiol. 2002;40:304-310.
-
(2002)
J Am Coll Cardiol.
, vol.40
, pp. 304-310
-
-
Cicoira, M.1
Zanolla, L.2
Rossi, A.3
Golia, G.4
Franceschini, L.5
Brighetti, G.6
Marino, P.7
Zardini, P.8
-
20
-
-
62449296975
-
Anti-Remodelling Effect of Canrenone in Patients with Mild Chronic Heart Failure (AREA IN-CHF study): Final results
-
Boccanelli A, Mureddu GF, Cacciatore G, Clemenza F, Di Lenarda A, Gavazzi A, Porcu M, Latini R, Lucci D, Maggioni AP, Masson S, Vanasia M, de Simone G. Anti-Remodelling Effect of Canrenone in Patients With Mild Chronic Heart Failure (AREA IN-CHF study): final results. Eur J Heart Fail. 2009;11:68-76.
-
(2009)
Eur J Heart Fail
, vol.11
, pp. 68-76
-
-
Boccanelli, A.1
Mureddu, G.F.2
Cacciatore, G.3
Clemenza, F.4
Di Lenarda, A.5
Gavazzi, A.6
Porcu, M.7
Latini, R.8
Lucci, D.9
Maggioni, A.P.10
Masson, S.11
Vanasia, M.12
De Simone, G.13
-
21
-
-
3543099842
-
Effect of al-dosterone antagonism on myocardial dysfunction in hypertensive patients with dia-stolic heart failure
-
Mottram PM, Haluska B, Leano R, Cowley D, Stowasser M, Marwick TH. Effect of al-dosterone antagonism on myocardial dysfunction in hypertensive patients with dia-stolic heart failure. Circulation. 2004;110: 558-565.
-
(2004)
Circulation
, vol.110
, pp. 558-565
-
-
Mottram, P.M.1
Haluska, B.2
Leano, R.3
Cowley, D.4
Stowasser, M.5
Marwick, T.H.6
-
22
-
-
33847193562
-
Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension
-
Pratt-Ubunama MN, Nishizaka MK, Boe-defeld RL, Cofield SS, Harding SM, Calhoun DA. Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension. Chest. 2007;131:453-459.
-
(2007)
Chest
, vol.131
, pp. 453-459
-
-
Pratt-Ubunama, M.N.1
Nishizaka, M.K.2
Boe-Defeld, R.L.3
Cofield, S.S.4
Harding, S.M.5
Calhoun, D.A.6
-
23
-
-
3042731163
-
Serum aldosterone and the incidence of hypertension in nonhypertensive persons
-
Vasan RS, Evans JC, Larson MG, Wilson PW, Meigs JB, Rifai N, Benjamin EJ, Levy D. Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med. 2004;351:33-41.
-
(2004)
N Engl J Med
, vol.351
, pp. 33-41
-
-
Vasan, R.S.1
Evans, J.C.2
Larson, M.G.3
Wilson, P.W.4
Meigs, J.B.5
Rifai, N.6
Benjamin, E.J.7
Levy, D.8
-
24
-
-
33748132658
-
A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients
-
Rossi GP, Bernini G, Caliumi C, Desideri G, Fabris B, Ferri C, Ganzaroli C, Giacchetti G, Letizia C, Maccario M, Mallamaci F, Mannelli M, Mattarello MJ, Moretti A, Palumbo G, Parenti G, Porteri E, Semplicini A, Rizzoni D, Rossi E, Boscaro M, Pessina AC, Mantero F. A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients. J Am Coll Cardiol. 2006;48: 2293-2300.
-
(2006)
J Am Coll Cardiol.
, vol.48
, pp. 2293-2300
-
-
Rossi, G.P.1
Bernini, G.2
Caliumi, C.3
Desideri, G.4
Fabris, B.5
Ferri, C.6
Ganzaroli, C.7
Giacchetti, G.8
Letizia, C.9
MacCario, M.10
Mallamaci, F.11
Mannelli, M.12
Mattarello, M.J.13
Moretti, A.14
Palumbo, G.15
Parenti, G.16
Porteri, E.17
Semplicini, A.18
Rizzoni, D.19
Rossi, E.20
Boscaro, M.21
Pessina, A.C.22
Mantero, F.23
more..
-
25
-
-
0036898286
-
Hyperaldoste-ronism among black and white subjects with resistant hypertension
-
Calhoun DA, Nishizaka MK, Zaman MA, Thakkar RB, Weissmann P. Hyperaldoste-ronism among black and white subjects with resistant hypertension. Hypertension. 2002; 40:892-896.
-
(2002)
Hypertension
, vol.40
, pp. 892-896
-
-
Calhoun, D.A.1
Nishizaka, M.K.2
Zaman, M.A.3
Thakkar, R.B.4
Weissmann, P.5
-
26
-
-
0042266234
-
Primary aldosteronism and hypertensive disease
-
Mosso L, Carvajal C, Gonzalez A, Barraza A, Avila F, Montero J, Huete A, Gederlini A, Fardella CE. Primary aldosteronism and hypertensive disease. Hypertension. 2003; 42:161-165.
-
(2003)
Hypertension
, vol.42
, pp. 161-165
-
-
Mosso, L.1
Carvajal, C.2
Gonzalez, A.3
Barraza, A.4
Avila, F.5
Montero, J.6
Huete, A.7
Gederlini, A.8
Fardella, C.E.9
-
27
-
-
17144421237
-
Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism
-
Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad JJ. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol. 2005;45:1243-1248.
-
(2005)
J Am Coll Cardiol.
, vol.45
, pp. 1243-1248
-
-
Milliez, P.1
Girerd, X.2
Plouin, P.F.3
Blacher, J.4
Safar, M.E.5
Mourad, J.J.6
-
28
-
-
40649118728
-
Spirono-lactone versus eplerenone for the treatment of idiopathic hyperaldosteronism
-
Karagiannis A, Tziomalos K, Papageorgiou A, Kakafika AI, Pagourelias ED, Anagnostis P, Athyros VG, Mikhailidis DP. Spirono-lactone versus eplerenone for the treatment of idiopathic hyperaldosteronism. Expert Opin Pharmacother. 2008;9:509-515.
-
(2008)
Expert Opin Pharmacother
, vol.9
, pp. 509-515
-
-
Karagiannis, A.1
Tziomalos, K.2
Papageorgiou, A.3
Kakafika, A.I.4
Pagourelias, E.D.5
Anagnostis, P.6
Athyros, V.G.7
Mikhailidis, D.P.8
-
29
-
-
0142231538
-
Efficacy of low-dose spironolactone in subjects with resistant hypertension
-
Nishizaka MK, Zaman MA, Calhoun DA. Efficacy of low-dose spironolactone in subjects with resistant hypertension. Am J Hypertens. 2003;16:925-930.
-
(2003)
Am J Hypertens
, vol.16
, pp. 925-930
-
-
Nishizaka, M.K.1
Zaman, M.A.2
Calhoun, D.A.3
-
30
-
-
34047197931
-
Effect of spironolactone on blood pressure in subjects with resistant hypertension
-
Chapman N, Dobson J, Wilson S, Dahlof B, Sever PS, Wedel H, Poulter NR. Effect of spironolactone on blood pressure in subjects with resistant hypertension. Hypertension. 2007;49:839-845.
-
(2007)
Hypertension
, vol.49
, pp. 839-845
-
-
Chapman, N.1
Dobson, J.2
Wilson, S.3
Dahlof, B.4
Sever, P.S.5
Wedel, H.6
Poulter, N.R.7
-
31
-
-
0037414091
-
Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients
-
Flack JM, Oparil S, Pratt JH, Roniker B, Garthwaite S, Kleiman JH, Yang Y, Krause SL, Workman D, Saunders E. Efficacy and tolerability of eplerenone and losartan in hypertensive black and white patients. J Am Coll Cardiol. 2003;41:1148-1155.
-
(2003)
J Am Coll Cardiol.
, vol.41
, pp. 1148-1155
-
-
Flack, J.M.1
Oparil, S.2
Pratt, J.H.3
Roniker, B.4
Garthwaite, S.5
Kleiman, J.H.6
Yang, Y.7
Krause, S.L.8
Workman, D.9
Saunders, E.10
-
32
-
-
38549140081
-
Selective mineralocorticoid receptor blocker eplerenone reduces resistance artery stiffness in hypertensive patients
-
Savoia C, Touyz RM, Amiri F, Schiffrin EL. Selective mineralocorticoid receptor blocker eplerenone reduces resistance artery stiffness in hypertensive patients. Hypertension. 2008;51:432-439.
-
(2008)
Hypertension
, vol.51
, pp. 432-439
-
-
Savoia, C.1
Touyz, R.M.2
Amiri, F.3
Schiffrin, E.L.4
-
33
-
-
35848931662
-
Long-term cardiac effects of adrenal-ectomy or mineralocorticoid antagonists in patients with primary aldosteronism
-
Catena C, Colussi G, Lapenna R, Nadalini E, Chiuch A, Gianfagna P, Sechi LA. Long-term cardiac effects of adrenal-ectomy or mineralocorticoid antagonists in patients with primary aldosteronism. Hypertension. 2007;50:911-918.
-
(2007)
Hypertension
, vol.50
, pp. 911-918
-
-
Catena, C.1
Colussi, G.2
Lapenna, R.3
Nadalini, E.4
Chiuch, A.5
Gianfagna, P.6
Sechi, L.A.7
-
34
-
-
0142085752
-
Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hyper tension and left ventricular hypertrophy: The 4E-Left Ventricular Hypertrophy Study
-
Pitt B, Reichek N, Willenbrock R, Zannad F, Phillips RA, Roniker B, Kleiman J, Krause S, Burns D, Williams GH. Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hyper tension and left ventricular hypertrophy: the 4E-Left Ventricular Hypertrophy Study. Circulation. 2003;108:1831-1838.
-
(2003)
Circulation
, vol.108
, pp. 1831-1838
-
-
Pitt, B.1
Reichek, N.2
Willenbrock, R.3
Zannad, F.4
Phillips, R.A.5
Roniker, B.6
Kleiman, J.7
Krause, S.8
Burns, D.9
Williams, G.H.10
-
35
-
-
33745079058
-
Long-term renal outcomes in patients with primary aldosteronism
-
DOI 10.1001/jama.295.22.2638
-
Sechi LA, Novello M, Lapenna R, Baroselli S, Nadalini E, Colussi GL, Catena C. Long-term renal outcomes in patients with primary aldosteronism. JAMA. 2006;295: 2638-2645. (Pubitemid 43882339)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.22
, pp. 2638-2645
-
-
Sechi, L.A.1
Novello, M.2
Lapenna, R.3
Baroselli, S.4
Nadalini, E.5
Colussi, G.L.6
Catena, C.7
-
36
-
-
33745282934
-
Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample
-
Fox CS, Larson MG, Hwang SJ, Leip EP, Rifai N, Levy D, Benjamin EJ, Murabito JM, Meigs JB, Vasan RS. Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample. Kidney Int. 2006;69:2064-2069.
-
(2006)
Kidney Int
, vol.69
, pp. 2064-2069
-
-
Fox, C.S.1
Larson, M.G.2
Hwang, S.J.3
Leip, E.P.4
Rifai, N.5
Levy, D.6
Benjamin, E.J.7
Murabito, J.M.8
Meigs, J.B.9
Vasan, R.S.10
-
37
-
-
66149131479
-
Aldosterone antagonists for preventing the progression of chronic kidney disease: A systematic review and meta-analysis
-
Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF. Aldosterone antagonists for preventing the progression of chronic kidney disease: a systematic review and meta-analysis. Clin J Am Soc Nephrol. 2009;4:542-551.
-
(2009)
Clin J Am Soc Nephrol
, vol.4
, pp. 542-551
-
-
Navaneethan, S.D.1
Nigwekar, S.U.2
Sehgal, A.R.3
Strippoli, G.F.4
|