-
1
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B, Belanger K, Hau P, Brandes AA, Gijtenbeek J, Marosi C, Vecht CJ, Mokhtari K, et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. The Lancet Oncology. 2009;10:459-466.
-
(2009)
The Lancet Oncology.
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
Ludwin, S.K.7
Allgeier, A.8
Fisher, B.9
Belanger, K.10
Hau, P.11
Brandes, A.A.12
Gijtenbeek, J.13
Marosi, C.14
Vecht, C.J.15
Mokhtari, K.16
-
2
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Identification of human brain tumour initiating cells. Nature. 2004;432:396-401.
-
(2004)
Nature.
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
3
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S, Fiocco R, Foroni C, Dimeco F, Vescovi A. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer research. 2004;64:7011-7021.
-
(2004)
Cancer research.
, vol.64
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
4
-
-
84923068676
-
Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
-
Zhou W, Ke SQ, Huang Z, Flavahan W, Fang X, Paul J, Wu L, Sloan AE, McLendon RE, Li X, Rich JN, Bao S. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth. Nature cell biology. 2015;17:170-182.
-
(2015)
Nature cell biology.
, vol.17
, pp. 170-182
-
-
Zhou, W.1
Ke, S.Q.2
Huang, Z.3
Flavahan, W.4
Fang, X.5
Paul, J.6
Wu, L.7
Sloan, A.E.8
McLendon, R.E.9
Li, X.10
Rich, J.N.11
Bao, S.12
-
5
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756-760.
-
(2006)
Nature.
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
6
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, Hjelmeland AB, Shi Q, McLendon RE, Bigner DD, Rich JN. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer research. 2006;66:7843-7848.
-
(2006)
Cancer research.
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
Hao, Y.4
Li, Z.5
Hjelmeland, A.B.6
Shi, Q.7
McLendon, R.E.8
Bigner, D.D.9
Rich, J.N.10
-
7
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
Liu G, Yuan X, Zeng Z, Tunici P, Ng H, Abdulkadir IR, Lu L, Irvin D, Black KL, Yu JS. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Molecular cancer. 2006;5:67.
-
(2006)
Molecular cancer.
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
Lu, L.7
Irvin, D.8
Black, K.L.9
Yu, J.S.10
-
8
-
-
46449115281
-
Stem cell-related "self- renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
-
Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, Hamou MF, de Tribolet N, Regli L, Wick W, Kouwenhoven MC, Hainfellner JA, Heppner FL, Dietrich PY, Zimmer Y, Cairncross JG, Janzer RC, et al. Stem cell-related "self- renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2008;26:3015-3024.
-
(2008)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology.
, vol.26
, pp. 3015-3024
-
-
Murat, A.1
Migliavacca, E.2
Gorlia, T.3
Lambiv, W.L.4
Shay, T.5
Hamou, M.F.6
de Tribolet, N.7
Regli, L.8
Wick, W.9
Kouwenhoven, M.C.10
Hainfellner, J.A.11
Heppner, F.L.12
Dietrich, P.Y.13
Zimmer, Y.14
Cairncross, J.G.15
Janzer, R.C.16
-
9
-
-
42949149114
-
Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria
-
Gunther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria. Oncogene. 2008;27:2897-2909.
-
(2008)
Oncogene.
, vol.27
, pp. 2897-2909
-
-
Gunther, H.S.1
Schmidt, N.O.2
Phillips, H.S.3
Kemming, D.4
Kharbanda, S.5
Soriano, R.6
Modrusan, Z.7
Meissner, H.8
Westphal, M.9
Lamszus, K.10
-
10
-
-
52049126634
-
Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase
-
Wakimoto N, Wolf I, Yin D, O'Kelly J, Akagi T, Abramovitz L, Black KL, Tai HH, Koeffler HP. Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase. Cancer research. 2008;68:6978-6986.
-
(2008)
Cancer research.
, vol.68
, pp. 6978-6986
-
-
Wakimoto, N.1
Wolf, I.2
Yin, D.3
O'Kelly, J.4
Akagi, T.5
Abramovitz, L.6
Black, K.L.7
Tai, H.H.8
Koeffler, H.P.9
-
11
-
-
79959969874
-
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
-
Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, Lathia JD, Forrester MT, Lee J, Stamler JS, Goldman SA, Bredel M, McLendon RE, Sloan AE, Hjelmeland AB, Rich JN. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell. 2011;146:53-66.
-
(2011)
Cell.
, vol.146
, pp. 53-66
-
-
Eyler, C.E.1
Wu, Q.2
Yan, K.3
MacSwords, J.M.4
Chandler-Militello, D.5
Misuraca, K.L.6
Lathia, J.D.7
Forrester, M.T.8
Lee, J.9
Stamler, J.S.10
Goldman, S.A.11
Bredel, M.12
McLendon, R.E.13
Sloan, A.E.14
Hjelmeland, A.B.15
Rich, J.N.16
-
12
-
-
79953757100
-
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3
-
Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, Yang J, MacSwords J, Eyler CE, McLendon RE, Heddleston JM, Shou W, Hambardzumyan D, Lee J, Hjelmeland AB, Sloan AE, Bredel M, et al. Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer cell. 2011;19:498-511.
-
(2011)
Cancer cell.
, vol.19
, pp. 498-511
-
-
Guryanova, O.A.1
Wu, Q.2
Cheng, L.3
Lathia, J.D.4
Huang, Z.5
Yang, J.6
MacSwords, J.7
Eyler, C.E.8
McLendon, R.E.9
Heddleston, J.M.10
Shou, W.11
Hambardzumyan, D.12
Lee, J.13
Hjelmeland, A.B.14
Sloan, A.E.15
Bredel, M.16
-
13
-
-
84884893986
-
Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake
-
Flavahan WA, Wu Q, Hitomi M, Rahim N, Kim Y, Sloan AE, Weil RJ, Nakano I, Sarkaria JN, Stringer BW, Day BW, Li M, Lathia JD, Rich JN, Hjelmeland AB. Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nature neuroscience. 2013;16:1373-1382.
-
(2013)
Nature neuroscience.
, vol.16
, pp. 1373-1382
-
-
Flavahan, W.A.1
Wu, Q.2
Hitomi, M.3
Rahim, N.4
Kim, Y.5
Sloan, A.E.6
Weil, R.J.7
Nakano, I.8
Sarkaria, J.N.9
Stringer, B.W.10
Day, B.W.11
Li, M.12
Lathia, J.D.13
Rich, J.N.14
Hjelmeland, A.B.15
-
14
-
-
84869210716
-
FoxM1 and Wnt/beta-catenin signaling in glioma stem cells
-
Gong A, Huang S. FoxM1 and Wnt/beta-catenin signaling in glioma stem cells. Cancer research. 2012;72:5658-5662.
-
(2012)
Cancer research.
, vol.72
, pp. 5658-5662
-
-
Gong, A.1
Huang, S.2
-
15
-
-
63249123273
-
TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma
-
Penuelas S, Anido J, Prieto-Sanchez RM, Folch G, Barba I, Cuartas I, Garcia-Dorado D, Poca MA, Sahuquillo J, Baselga J, Seoane J. TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma. Cancer cell. 2009;15:315-327.
-
(2009)
Cancer cell.
, vol.15
, pp. 315-327
-
-
Penuelas, S.1
Anido, J.2
Prieto-Sanchez, R.M.3
Folch, G.4
Barba, I.5
Cuartas, I.6
Garcia-Dorado, D.7
Poca, M.A.8
Sahuquillo, J.9
Baselga, J.10
Seoane, J.11
-
16
-
-
84870853546
-
The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas
-
Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, et al. The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer cell. 2012;22:765-780.
-
(2012)
Cancer cell.
, vol.22
, pp. 765-780
-
-
Binda, E.1
Visioli, A.2
Giani, F.3
Lamorte, G.4
Copetti, M.5
Pitter, K.L.6
Huse, J.T.7
Cajola, L.8
Zanetti, N.9
DiMeco, F.10
De Filippis, L.11
Mangiola, A.12
Maira, G.13
Anile, C.14
De Bonis, P.15
Reynolds, B.A.16
-
17
-
-
80054774352
-
FoxM1 promotes beta-catenin nuclear localization and controls Wnt targetgene expression and glioma tumorigenesis
-
Zhang N, Wei P, Gong A, Chiu WT, Lee HT, Colman H, Huang H, Xue J, Liu M, Wang Y, Sawaya R, Xie K, Yung WK, Medema RH, He X, Huang S. FoxM1 promotes beta-catenin nuclear localization and controls Wnt targetgene expression and glioma tumorigenesis. Cancer cell. 2011;20:427-442.
-
(2011)
Cancer cell.
, vol.20
, pp. 427-442
-
-
Zhang, N.1
Wei, P.2
Gong, A.3
Chiu, W.T.4
Lee, H.T.5
Colman, H.6
Huang, H.7
Xue, J.8
Liu, M.9
Wang, Y.10
Sawaya, R.11
Xie, K.12
Yung, W.K.13
Medema, R.H.14
He, X.15
Huang, S.16
-
19
-
-
84858004513
-
USP15 stabilizes TGF-beta receptor I and promotes oncogenesis through the activation of TGF- beta signaling in glioblastoma
-
Eichhorn PJ, Rodon L, Gonzalez-Junca A, Dirac A, Gili M, Martinez-Saez E, Aura C, Barba I, Peg V, Prat A, Cuartas I, Jimenez J, Garcia-Dorado D, Sahuquillo J, Bernards R, Baselga J, et al. USP15 stabilizes TGF-beta receptor I and promotes oncogenesis through the activation of TGF- beta signaling in glioblastoma. Nature medicine. 2012;18:429-435.
-
(2012)
Nature medicine.
, vol.18
, pp. 429-435
-
-
Eichhorn, P.J.1
Rodon, L.2
Gonzalez-Junca, A.3
Dirac, A.4
Gili, M.5
Martinez-Saez, E.6
Aura, C.7
Barba, I.8
Peg, V.9
Prat, A.10
Cuartas, I.11
Jimenez, J.12
Garcia-Dorado, D.13
Sahuquillo, J.14
Bernards, R.15
Baselga, J.16
-
20
-
-
84861582362
-
Ubiquitination and deubiquitination of REST and its roles in cancers
-
Huang Z, Bao S. Ubiquitination and deubiquitination of REST and its roles in cancers. FEBS letters. 2012;586:1602-1605.
-
(2012)
FEBS letters.
, vol.586
, pp. 1602-1605
-
-
Huang, Z.1
Bao, S.2
-
21
-
-
34250799719
-
Cdc20: a WD40 activator for a cell cycle degradation machine
-
Yu H. Cdc20: a WD40 activator for a cell cycle degradation machine. Molecular cell. 2007;27:3-16.
-
(2007)
Molecular cell.
, vol.27
, pp. 3-16
-
-
Yu, H.1
-
22
-
-
84902543340
-
Cdc20 and securin overexpression predict short-term breast cancer survival
-
Karra H, Repo H, Ahonen I, Loyttyniemi E, Pitkanen R, Lintunen M, Kuopio T, Soderstrom M, Kronqvist P. Cdc20 and securin overexpression predict short-term breast cancer survival. British journal of cancer. 2014;110:2905-2913.
-
(2014)
British journal of cancer.
, vol.110
, pp. 2905-2913
-
-
Karra, H.1
Repo, H.2
Ahonen, I.3
Loyttyniemi, E.4
Pitkanen, R.5
Lintunen, M.6
Kuopio, T.7
Soderstrom, M.8
Kronqvist, P.9
-
23
-
-
84878684149
-
CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer
-
Wu WJ, Hu KS, Wang DS, Zeng ZL, Zhang DS, Chen DL, Bai L, Xu RH. CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer. Journal of translational medicine. 2013;11:142.
-
(2013)
Journal of translational medicine.
, vol.11
, pp. 142
-
-
Wu, W.J.1
Hu, K.S.2
Wang, D.S.3
Zeng, Z.L.4
Zhang, D.S.5
Chen, D.L.6
Bai, L.7
Xu, R.H.8
-
24
-
-
33845657904
-
Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer
-
Mondal G, Sengupta S, Panda CK, Gollin SM, Saunders WS, Roychoudhury S. Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancer. Carcinogenesis. 2007;28:81-92.
-
(2007)
Carcinogenesis.
, vol.28
, pp. 81-92
-
-
Mondal, G.1
Sengupta, S.2
Panda, C.K.3
Gollin, S.M.4
Saunders, W.S.5
Roychoudhury, S.6
-
25
-
-
84878833718
-
Cdc20: a potential novel therapeutic target for cancer treatment
-
Wang Z, Wan L, Zhong J, Inuzuka H, Liu P, Sarkar FH, Wei W. Cdc20: a potential novel therapeutic target for cancer treatment. Current pharmaceutical design. 2013;19:3210-3214.
-
(2013)
Current pharmaceutical design.
, vol.19
, pp. 3210-3214
-
-
Wang, Z.1
Wan, L.2
Zhong, J.3
Inuzuka, H.4
Liu, P.5
Sarkar, F.H.6
Wei, W.7
-
26
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
Roadmap Epigenomics C, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, et al. Integrative analysis of 111 reference human epigenomes. Nature. 2015;518:317-330.
-
(2015)
Nature.
, vol.518
, pp. 317-330
-
-
Roadmap Epigenomics, C.1
Kundaje, A.2
Meuleman, W.3
Ernst, J.4
Bilenky, M.5
Yen, A.6
Heravi-Moussavi, A.7
Kheradpour, P.8
Zhang, Z.9
Wang, J.10
Ziller, M.J.11
Amin, V.12
Whitaker, J.W.13
Schultz, M.D.14
Ward, L.D.15
Sarkar, A.16
-
27
-
-
84899524502
-
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
-
Suva ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 2014;157:580-594.
-
(2014)
Cell.
, vol.157
, pp. 580-594
-
-
Suva, M.L.1
Rheinbay, E.2
Gillespie, S.M.3
Patel, A.P.4
Wakimoto, H.5
Rabkin, S.D.6
Riggi, N.7
Chi, A.S.8
Cahill, D.P.9
Nahed, B.V.10
Curry, W.T.11
Martuza, R.L.12
Rivera, M.N.13
Rossetti, N.14
Kasif, S.15
Beik, S.16
-
28
-
-
84905497126
-
Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines
-
Das T, Roy KS, Chakrabarti T, Mukhopadhyay S, Roychoudhury S. Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines. Biochemical pharmacology. 2014;91:31-39.
-
(2014)
Biochemical pharmacology.
, vol.91
, pp. 31-39
-
-
Das, T.1
Roy, K.S.2
Chakrabarti, T.3
Mukhopadhyay, S.4
Roychoudhury, S.5
-
29
-
-
34547174700
-
APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase
-
Amador V, Ge S, Santamaria PG, Guardavaccaro D, Pagano M. APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Molecular cell. 2007;27:462-473.
-
(2007)
Molecular cell.
, vol.27
, pp. 462-473
-
-
Amador, V.1
Ge, S.2
Santamaria, P.G.3
Guardavaccaro, D.4
Pagano, M.5
-
30
-
-
33846815345
-
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
-
Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron. 2007;53:503-517.
-
(2007)
Neuron.
, vol.53
, pp. 503-517
-
-
Ligon, K.L.1
Huillard, E.2
Mehta, S.3
Kesari, S.4
Liu, H.5
Alberta, J.A.6
Bachoo, R.M.7
Kane, M.8
Louis, D.N.9
Depinho, R.A.10
Anderson, D.J.11
Stiles, C.D.12
Rowitch, D.H.13
-
31
-
-
51049101689
-
Targeting cancer stem cells through L1CAM suppresses glioma growth
-
Bao S, Wu Q, Li Z, Sathornsumetee S, Wang H, McLendon RE, Hjelmeland AB, Rich JN. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer research. 2008;68:6043-6048.
-
(2008)
Cancer research.
, vol.68
, pp. 6043-6048
-
-
Bao, S.1
Wu, Q.2
Li, Z.3
Sathornsumetee, S.4
Wang, H.5
McLendon, R.E.6
Hjelmeland, A.B.7
Rich, J.N.8
-
32
-
-
56849131763
-
c-Myc is required for maintenance of glioma cancer stem cells
-
Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN. c-Myc is required for maintenance of glioma cancer stem cells. PloS one. 2008;3:e3769.
-
(2008)
PloS one.
, vol.3
, pp. e3769
-
-
Wang, J.1
Wang, H.2
Li, Z.3
Wu, Q.4
Lathia, J.D.5
McLendon, R.E.6
Hjelmeland, A.B.7
Rich, J.N.8
-
33
-
-
84905856772
-
Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival
-
Zhu Z, Khan MA, Weiler M, Blaes J, Jestaedt L, Geibert M, Zou P, Gronych J, Bernhardt O, Korshunov A, Bugner V, Lichter P, Radlwimmer B, Heiland S, Bendszus M, Wick W, et al. Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival. Cell stem cell. 2014;15:185-198.
-
(2014)
Cell stem cell.
, vol.15
, pp. 185-198
-
-
Zhu, Z.1
Khan, M.A.2
Weiler, M.3
Blaes, J.4
Jestaedt, L.5
Geibert, M.6
Zou, P.7
Gronych, J.8
Bernhardt, O.9
Korshunov, A.10
Bugner, V.11
Lichter, P.12
Radlwimmer, B.13
Heiland, S.14
Bendszus, M.15
Wick, W.16
-
34
-
-
84872728523
-
Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress
-
Dai B, Gong A, Jing Z, Aldape KD, Kang SH, Sawaya R, Huang S. Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress. The Journal of biological chemistry. 2013;288:1634-1642.
-
(2013)
The Journal of biological chemistry.
, vol.288
, pp. 1634-1642
-
-
Dai, B.1
Gong, A.2
Jing, Z.3
Aldape, K.D.4
Kang, S.H.5
Sawaya, R.6
Huang, S.7
-
35
-
-
84922574009
-
EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/ FOXM1-Dependent Manner
-
Kim SH, Joshi K, Ezhilarasan R, Myers TR, Siu J, Gu C, Nakano-Okuno M, Taylor D, Minata M, Sulman EP, Lee J, Bhat KP, Salcini AE, Nakano I. EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/ FOXM1-Dependent Manner. Stem cell reports. 2015;4:226-238.
-
(2015)
Stem cell reports.
, vol.4
, pp. 226-238
-
-
Kim, S.H.1
Joshi, K.2
Ezhilarasan, R.3
Myers, T.R.4
Siu, J.5
Gu, C.6
Nakano-Okuno, M.7
Taylor, D.8
Minata, M.9
Sulman, E.P.10
Lee, J.11
Bhat, K.P.12
Salcini, A.E.13
Nakano, I.14
-
36
-
-
84878000228
-
MELK- dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells
-
Joshi K, Banasavadi-Siddegowda Y, Mo X, Kim SH, Mao P, Kig C, Nardini D, Sobol RW, Chow LM, Kornblum HI, Waclaw R, Beullens M, Nakano I. MELK- dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells. Stem cells. 2013;31:1051-1063.
-
(2013)
Stem cells.
, vol.31
, pp. 1051-1063
-
-
Joshi, K.1
Banasavadi-Siddegowda, Y.2
Mo, X.3
Kim, S.H.4
Mao, P.5
Kig, C.6
Nardini, D.7
Sobol, R.W.8
Chow, L.M.9
Kornblum, H.I.10
Waclaw, R.11
Beullens, M.12
Nakano, I.13
-
37
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001;414:105-111.
-
(2001)
Nature.
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
38
-
-
84899790169
-
Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche
-
Codega P, Silva-Vargas V, Paul A, Maldonado-Soto AR, Deleo AM, Pastrana E, Doetsch F. Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche. Neuron. 2014;82:545-559.
-
(2014)
Neuron.
, vol.82
, pp. 545-559
-
-
Codega, P.1
Silva-Vargas, V.2
Paul, A.3
Maldonado-Soto, A.R.4
Deleo, A.M.5
Pastrana, E.6
Doetsch, F.7
-
39
-
-
0027941902
-
A self-renewing multipotential stem cell in embryonic rat cerebral cortex
-
Davis AA, Temple S. A self-renewing multipotential stem cell in embryonic rat cerebral cortex. Nature. 1994;372:263-266.
-
(1994)
Nature.
, vol.372
, pp. 263-266
-
-
Davis, A.A.1
Temple, S.2
-
40
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell. 1999;97:703-716.
-
(1999)
Cell.
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
41
-
-
84884844190
-
The cell-cycle state of stem cells determines cell fate propensity
-
Pauklin S, Vallier L. The cell-cycle state of stem cells determines cell fate propensity. Cell. 2013;155:135-147.
-
(2013)
Cell.
, vol.155
, pp. 135-147
-
-
Pauklin, S.1
Vallier, L.2
-
42
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nature genetics. 2008;40:499-507.
-
(2008)
Nature genetics.
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
43
-
-
59849125142
-
SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity
-
Gangemi RM, Griffero F, Marubbi D, Perera M, Capra MC, Malatesta P, Ravetti GL, Zona GL, Daga A, Corte G. SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem cells. 2009;27:40-48.
-
(2009)
Stem cells.
, vol.27
, pp. 40-48
-
-
Gangemi, R.M.1
Griffero, F.2
Marubbi, D.3
Perera, M.4
Capra, M.C.5
Malatesta, P.6
Ravetti, G.L.7
Zona, G.L.8
Daga, A.9
Corte, G.10
-
44
-
-
54549095950
-
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
-
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, et al. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature. 2008;455:1129-1133.
-
(2008)
Nature.
, vol.455
, pp. 1129-1133
-
-
Zheng, H.1
Ying, H.2
Yan, H.3
Kimmelman, A.C.4
Hiller, D.J.5
Chen, A.J.6
Perry, S.R.7
Tonon, G.8
Chu, G.C.9
Ding, Z.10
Stommel, J.M.11
Dunn, K.L.12
Wiedemeyer, R.13
You, M.J.14
Brennan, C.15
Wang, Y.A.16
-
46
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007;449:1003-1007.
-
(2007)
Nature.
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
van Es, J.H.2
Kuipers, J.3
Kujala, P.4
van den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
Clevers, H.11
-
47
-
-
67649643776
-
Very long-term self-renewal of small intestine, colon, and hair follicles from cycling Lgr5+ve stem cells
-
Barker N, van Es JH, Jaks V, Kasper M, Snippert H, Toftgard R, Clevers H. Very long-term self-renewal of small intestine, colon, and hair follicles from cycling Lgr5+ve stem cells. Cold Spring Harbor symposia on quantitative biology. 2008;73:351-356.
-
(2008)
Cold Spring Harbor symposia on quantitative biology.
, vol.73
, pp. 351-356
-
-
Barker, N.1
van Es, J.H.2
Jaks, V.3
Kasper, M.4
Snippert, H.5
Toftgard, R.6
Clevers, H.7
-
48
-
-
78650002007
-
Non-stem cell origin for oligodendroglioma
-
Persson AI, Petritsch C, Swartling FJ, Itsara M, Sim FJ, Auvergne R, Goldenberg DD, Vandenberg SR, Nguyen KN, Yakovenko S, Ayers-Ringler J, Nishiyama A, Stallcup WB, Berger MS, Bergers G, McKnight TR, et al. Non-stem cell origin for oligodendroglioma. Cancer cell. 2010;18:669-682.
-
(2010)
Cancer cell.
, vol.18
, pp. 669-682
-
-
Persson, A.I.1
Petritsch, C.2
Swartling, F.J.3
Itsara, M.4
Sim, F.J.5
Auvergne, R.6
Goldenberg, D.D.7
Vandenberg, S.R.8
Nguyen, K.N.9
Yakovenko, S.10
Ayers-Ringler, J.11
Nishiyama, A.12
Stallcup, W.B.13
Berger, M.S.14
Bergers, G.15
McKnight, T.R.16
-
49
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, Vogel H, Foreman O, Bronson RT, Nishiyama A, Luo L, Zong H. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell. 2011;146:209-221.
-
(2011)
Cell.
, vol.146
, pp. 209-221
-
-
Liu, C.1
Sage, J.C.2
Miller, M.R.3
Verhaak, R.G.4
Hippenmeyer, S.5
Vogel, H.6
Foreman, O.7
Bronson, R.T.8
Nishiyama, A.9
Luo, L.10
Zong, H.11
-
50
-
-
84869878282
-
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice
-
Friedmann-Morvinski D, Bushong EA, Ke E, Soda Y, Marumoto T, Singer O, Ellisman MH, Verma IM. Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science. 2012;338:1080-1084.
-
(2012)
Science.
, vol.338
, pp. 1080-1084
-
-
Friedmann-Morvinski, D.1
Bushong, E.A.2
Ke, E.3
Soda, Y.4
Marumoto, T.5
Singer, O.6
Ellisman, M.H.7
Verma, I.M.8
-
51
-
-
57849109837
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer cell. 2009;15:45-56.
-
(2009)
Cancer cell.
, vol.15
, pp. 45-56
-
-
Alcantara Llaguno, S.1
Chen, J.2
Kwon, C.H.3
Jackson, E.L.4
Li, Y.5
Burns, D.K.6
Alvarez-Buylla, A.7
Parada, L.F.8
-
52
-
-
84902668801
-
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suva ML, Regev A, Bernstein BE. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science. 2014;344:1396-1401.
-
(2014)
Science.
, vol.344
, pp. 1396-1401
-
-
Patel, A.P.1
Tirosh, I.2
Trombetta, J.J.3
Shalek, A.K.4
Gillespie, S.M.5
Wakimoto, H.6
Cahill, D.P.7
Nahed, B.V.8
Curry, W.T.9
Martuza, R.L.10
Louis, D.N.11
Rozenblatt-Rosen, O.12
Suva, M.L.13
Regev, A.14
Bernstein, B.E.15
-
53
-
-
79957472391
-
Evidence for label-retaining tumour-initiating cells in human glioblastoma
-
Deleyrolle LP, Harding A, Cato K, Siebzehnrubl FA, Rahman M, Azari H, Olson S, Gabrielli B, Osborne G, Vescovi A, Reynolds BA. Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain: a journal of neurology. 2011;134:1331-1343.
-
(2011)
Brain: a journal of neurology.
, vol.134
, pp. 1331-1343
-
-
Deleyrolle, L.P.1
Harding, A.2
Cato, K.3
Siebzehnrubl, F.A.4
Rahman, M.5
Azari, H.6
Olson, S.7
Gabrielli, B.8
Osborne, G.9
Vescovi, A.10
Reynolds, B.A.11
-
54
-
-
58149340463
-
Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme
-
Pallini R, Ricci-Vitiani L, Banna GL, Signore M, Lombardi D, Todaro M, Stassi G, Martini M, Maira G, Larocca LM, De Maria R. Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme. Clinical cancer research: an official journal of the American Association for Cancer Research. 2008;14:8205-8212.
-
(2008)
Clinical cancer research: an official journal of the American Association for Cancer Research.
, vol.14
, pp. 8205-8212
-
-
Pallini, R.1
Ricci-Vitiani, L.2
Banna, G.L.3
Signore, M.4
Lombardi, D.5
Todaro, M.6
Stassi, G.7
Martini, M.8
Maira, G.9
Larocca, L.M.10
De Maria, R.11
-
55
-
-
84873929643
-
Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells
-
Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, DeLuca J, et al. Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells. Cancer discovery. 2013;3:198-211.
-
(2013)
Cancer discovery.
, vol.3
, pp. 198-211
-
-
Ding, Y.1
Hubert, C.G.2
Herman, J.3
Corrin, P.4
Toledo, C.M.5
Skutt-Kakaria, K.6
Vazquez, J.7
Basom, R.8
Zhang, B.9
Risler, J.K.10
Pollard, S.M.11
Nam, D.H.12
Delrow, J.J.13
Zhu, J.14
Lee, J.15
DeLuca, J.16
-
57
-
-
40449137094
-
CDC20, a potential cancer therapeutic target, is negatively regulated by p53
-
Kidokoro T, Tanikawa C, Furukawa Y, Katagiri T, Nakamura Y, Matsuda K. CDC20, a potential cancer therapeutic target, is negatively regulated by p53. Oncogene. 2008;27:1562-1571.
-
(2008)
Oncogene.
, vol.27
, pp. 1562-1571
-
-
Kidokoro, T.1
Tanikawa, C.2
Furukawa, Y.3
Katagiri, T.4
Nakamura, Y.5
Matsuda, K.6
-
58
-
-
80053991470
-
The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression
-
Bie L, Zhao G, Cheng P, Rondeau G, Porwollik S, Ju Y, Xia XQ, McClelland M. The accuracy of survival time prediction for patients with glioma is improved by measuring mitotic spindle checkpoint gene expression. PloS one. 2011;6:e25631.
-
(2011)
PloS one.
, vol.6
, pp. e25631
-
-
Bie, L.1
Zhao, G.2
Cheng, P.3
Rondeau, G.4
Porwollik, S.5
Ju, Y.6
Xia, X.Q.7
McClelland, M.8
-
59
-
-
55849100002
-
Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20
-
Marucci G, Morandi L, Magrini E, Farnedi A, Franceschi E, Miglio R, Calo D, Pession A, Foschini MP, Eusebi V. Gene expression profiling in glioblastoma and immunohistochemical evaluation of IGFBP-2 and CDC20. Virchows Archiv:an international journal of pathology. 2008;453:599-609.
-
(2008)
Virchows Archiv:an international journal of pathology.
, vol.453
, pp. 599-609
-
-
Marucci, G.1
Morandi, L.2
Magrini, E.3
Farnedi, A.4
Franceschi, E.5
Miglio, R.6
Calo, D.7
Pession, A.8
Foschini, M.P.9
Eusebi, V.10
-
60
-
-
84901433308
-
APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction
-
Wan L, Tan M, Yang J, Inuzuka H, Dai X, Wu T, Liu J, Shaik S, Chen G, Deng J, Malumbres M, Letai A, Kirschner MW, Sun Y, Wei W. APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction. Developmental cell. 2014;29:377-391.
-
(2014)
Developmental cell.
, vol.29
, pp. 377-391
-
-
Wan, L.1
Tan, M.2
Yang, J.3
Inuzuka, H.4
Dai, X.5
Wu, T.6
Liu, J.7
Shaik, S.8
Chen, G.9
Deng, J.10
Malumbres, M.11
Letai, A.12
Kirschner, M.W.13
Sun, Y.14
Wei, W.15
-
61
-
-
84931079235
-
Association of survivin splice variants with prognosis and treatment of breast cancer
-
Pavlidou A, Kroupis C, Dimas K. Association of survivin splice variants with prognosis and treatment of breast cancer. World journal of clinical oncology. 2014;5:883-894.
-
(2014)
World journal of clinical oncology.
, vol.5
, pp. 883-894
-
-
Pavlidou, A.1
Kroupis, C.2
Dimas, K.3
-
62
-
-
84893864404
-
Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy
-
Wang W, Ji W, Hu H, Ma J, Li X, Mei W, Xu Y, Hu H, Yan Y, Song Q, Li Z, Su C. Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy. Oncotarget. 2014;5:150-160.
-
(2014)
Oncotarget.
, vol.5
, pp. 150-160
-
-
Wang, W.1
Ji, W.2
Hu, H.3
Ma, J.4
Li, X.5
Mei, W.6
Xu, Y.7
Hu, H.8
Yan, Y.9
Song, Q.10
Li, Z.11
Su, C.12
-
63
-
-
84898005888
-
ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer
-
Ye Q, Cai W, Zheng Y, Evers BM, She QB. ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer. Oncogene. 2014;33:1828-1839.
-
(2014)
Oncogene.
, vol.33
, pp. 1828-1839
-
-
Ye, Q.1
Cai, W.2
Zheng, Y.3
Evers, B.M.4
She, Q.B.5
-
64
-
-
80053647284
-
Chemoresistance of glioblastoma cancer stem cells-much more complex than expected
-
Beier D, Schulz JB, Beier CP. Chemoresistance of glioblastoma cancer stem cells-much more complex than expected. Molecular cancer. 2011;10:128.
-
(2011)
Molecular cancer.
, vol.10
, pp. 128
-
-
Beier, D.1
Schulz, J.B.2
Beier, C.P.3
-
65
-
-
77957947338
-
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage
-
Zeng X, Sigoillot F, Gaur S, Choi S, Pfaff KL, Oh DC, Hathaway N, Dimova N, Cuny GD, King RW. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer cell. 2010;18:382-395.
-
(2010)
Cancer cell.
, vol.18
, pp. 382-395
-
-
Zeng, X.1
Sigoillot, F.2
Gaur, S.3
Choi, S.4
Pfaff, K.L.5
Oh, D.C.6
Hathaway, N.7
Dimova, N.8
Cuny, G.D.9
King, R.W.10
-
66
-
-
84908408865
-
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C
-
Sackton KL, Dimova N, Zeng X, Tian W, Zhang M, Sackton TB, Meaders J, Pfaff KL, Sigoillot F, Yu H, Luo X, King RW. Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature. 2014;514:646-649.
-
(2014)
Nature.
, vol.514
, pp. 646-649
-
-
Sackton, K.L.1
Dimova, N.2
Zeng, X.3
Tian, W.4
Zhang, M.5
Sackton, T.B.6
Meaders, J.7
Pfaff, K.L.8
Sigoillot, F.9
Yu, H.10
Luo, X.11
King, R.W.12
|