Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain

Human Mutation

Volumn 36, Issue 7, 2015, Pages 704-711

  Komine, Keigo ^a,b   Shimodaira, Hideki ^a,b   Takao, Masashi ^a   Soeda, Hiroshi ^a,b   Zhang, Xiaofei ^a   Takahashi, Masanobu ^a,b   Ishioka, Chikashi ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY HOSPITAL   (Japan)

Author keywords

Functional assay; MAP; MUTYH; Polyposis; Prediction

Indexed keywords

DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; ISOPROTEIN;

ADENOMATOUS POLYP; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL STRAIN; CELLULAR DISTRIBUTION; COLON POLYPOSIS; CONTROLLED STUDY; DNA BINDING; DNA GLYCOSYLASE MUTY ASSOCIATED POLYPOSIS; DNA SEQUENCE; ENZYME ACTIVE SITE; ESCHERICHIA COLI; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENETIC COMPLEMENTATION; GENETIC VARIABILITY; HCT116 CELL LINE; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; SPONTANEOUS MUTATION; TRANSLATION INITIATION; BIOASSAY; CHEMISTRY; COLORECTAL TUMOR; GENE VECTOR; GENETICS; METABOLISM; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR CELL LINE;

ESCHERICHIA COLI;

ADENOMATOUS POLYPOSIS COLI; BIOLOGICAL ASSAY; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA GLYCOSYLASES; ESCHERICHIA COLI; GENETIC VECTORS; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS;

EID: 84931043936     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.22794     Document Type: Article

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