Design and synthesis of new benzimidazole and pyrimidine derivatives as α-glucosidase inhibitor

Iranian Journal of Pharmaceutical Research

Volumn 14, Issue 3, 2015, Pages 723-731

  Mobinikhaledi, Akbar ^a   Asghari, Behvar ^b   Jabbarpoura, Mahsa ^a  

^a ARAK UNIVERSITY   (Iran)

^b IMAM KHOMEINI INTERNATIONAL UNIVERSITY   (Iran)

Author keywords

Amino acids; Antihyperglycemic activity; Benzimidazole; Pyrimidine; glucosidase inhibition

Indexed keywords

2 ((1H BENZO(D)IMIDAZOL 2 YL)METHYL)ISOINDOLINE 1,3 DIONE; 2 ((1H PERIMIDIN 2 YL)METHYL)ISOINDOLINE 1,3 DIONE; 2 (1 (1H BENZO(D)IMIDAZOL 2 YL) 2 (4 HYDROXYPHENYL)ETHYL)ISOINDOLINE 1,3 DIONE; 2 (1 (1H BENZO(D)IMIDAZOL 2 YL) 2 METHYLBUTYL)ISOINDOLINE 1,3 DIONE; 2 (1 (1H BENZO(D)IMIDAZOL 2 YL) 2 PHENYLETHYL)ISOINDOLINE 1,3 DIONE; 2 (1 (1H PERIMIDIN 2 YL) 2 PHENYLETHYL)ISOINDOLINE 1,3 DIONE; 2 (1,3 DIOXOISOINDOLIN 2 YL) 3 PHENYLPROPANOIC ACID; 2 (1,3 DIOXOISOINDOLIN 2 YL)ACETIC ACID; 2 (2 (4 HYDROXYPHENYL) 1 (1H PERIMIDIN 2 YL)ETHYL)ISOINDOLINE 1,3 DIONE; 2 (2 METHYL 1 (1H PERIMIDIN 2 YL)BUTYL)ISOINDOLINE 1,3 DIONE; 2 (3 METHYL 1 (1H PERIMIDIN 2 YL)BUTYL)ISOINDOLINE 1,3 DIONE; 3 (4 HYDROXYPHENYL) 2 (1,3 DIOXOISOINDOLIN 2 YL)PROPANOIC ACID; 3 METHYL 2 (1,3 DIOXOISOINDOLIN 2 YL)PENTANOIC ACID; 4 METHYL 2 (1,3 DIOXOISOINDOLIN 2 YL)PENTANOIC ACID; ACARBOSE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR; AROMATIC AMINO ACID; BENZIMIDAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTICAL PARAMETERS; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DESIGN; DRUG SYNTHESIS; ELEMENTAL ANALYSIS; ENZYME INHIBITION ASSAY; GROWTH INHIBITION; IC50; INFRARED SPECTROSCOPY; MICROPLATE READER; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRETCHING VIBRATION; YEAST;

EID: 84931034143     PISSN: 17350328     EISSN: 17266890     Source Type: Journal    
DOI: None     Document Type: Article

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