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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5975-5977

Synthesis and cytotoxicity of 8-cyano-3-substitutedalkyl-5-methyl-4- methylene-7-methoxy-3,4-dihydropyrido[4,3-d]pyrimidines

(5) Mo, Wen Yan a Liang, Yong Ju b Gu, Yu Cheng a,c Fu, Li Wu b He, Hong Wu a

a CENTRAL CHINA NORMAL UNIVERSITY (China)

b SUN YAT SEN UNIVERSITY CANCER CENTER (China)

c JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE (United Kingdom)

Author keywords

Antitumor activity; MTT; Pyrido 4,3 d pyrimidine; Synthesis

Indexed keywords

BENZYL DERIVATIVE; CARBENE; DIHYDROPYRIDINE DERIVATIVE; FLUOROURACIL; NITRILE; PYRIMIDINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

ANTIMETABOLITES, ANTINEOPLASTIC; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FLUOROURACIL; HUMANS; INHIBITORY CONCENTRATION 50; KB CELLS; NEOPLASMS; PYRIMIDINES;

EID: 80052576890 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.07.067 Document Type: Article

Times cited : (18)

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