Exosomal miR-21 derived from arsenite-transformed human bronchial epithelial cells promotes cell proliferation associated with arsenite carcinogenesis

Archives of Toxicology

Volumn 89, Issue 7, 2015, Pages 1071-1082

  Xu, Yuan ^a,b   Luo, Fei ^a,b   Liu, Yi ^a,b   Shi, Le ^a,b   Lu, Xiaolin ^a,b   Xu, Wenchao ^a,b   Liu, Qizhan ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Nanjing Medical University   (China)

Author keywords

Arsenite; Carcinogenesis; Exosomal miRNAs; Intercellular communication

Indexed keywords

ARSENIC TRIOXIDE; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RNA; ARSENATE SODIUM; ARSENIC ACID DERIVATIVE; IL6 PROTEIN, HUMAN; INTERLEUKIN 6; MICRORNA; MIRN21 MICRORNA, HUMAN; PTEN PROTEIN, HUMAN; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN;

ARTICLE; BRONCHUS MUCOSA; CELL COMMUNICATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; EPITHELIUM CELL; EXOSOME; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CARCINOGENESIS; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; BRONCHUS; CHEMICALLY INDUCED; COCULTURE; DRUG EFFECTS; GENETICS; METABOLISM; PARACRINE SIGNALING; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR; TRANSFORMED CELL LINE; UPREGULATION;

ARSENATES; BRONCHI; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COCULTURE TECHNIQUES; EPITHELIAL CELLS; EXOSOMES; HUMANS; INTERLEUKIN-6; MICRORNAS; PARACRINE COMMUNICATION; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84930931747     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-014-1291-x     Document Type: Article

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