-
1
-
-
0026700235
-
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
-
Ishida Y, Agata Y, Shibahara K, Honjo T: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J 1992; 11: 3887-3895.
-
(1992)
EMBO J
, vol.11
, pp. 3887-3895
-
-
Ishida, Y.1
Agata, Y.2
Shibahara, K.3
Honjo, T.4
-
3
-
-
0242303572
-
Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses
-
Liang SC, Latchman YE, Buhlmann JE, Tomczak MF, Horwitz BH, Freeman GJ, Sharpe AH: Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses. Eur J Immunol 2003; 33: 2706-2716.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2706-2716
-
-
Liang, S.C.1
Latchman, Y.E.2
Buhlmann, J.E.3
Tomczak, M.F.4
Horwitz, B.H.5
Freeman, G.J.6
Sharpe, A.H.7
-
4
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Agata Y, Kawasaki A, Nishimura H, Ishida Y, Tsubata T, Yagita H, Honjo T: Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 1996; 8: 765-772.
-
(1996)
Int Immunol
, vol.8
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
Ishida, Y.4
Tsubata, T.5
Yagita, H.6
Honjo, T.7
-
5
-
-
33745197352
-
Blockade of PDL1 (B7-H1) augments human tumor-specific T cell responses in vitro
-
Blank C, Kuball J, Voelkl S, Wiendl H, Becker B, Walter B, Majdic O, Gajewski TF, Theobald M, Andreesen R, Mackensen A: Blockade of PDL1 (B7-H1) augments human tumor-specific T cell responses in vitro. Int J Cancer 2006; 119: 317-327.
-
(2006)
Int J Cancer
, vol.119
, pp. 317-327
-
-
Blank, C.1
Kuball, J.2
Voelkl, S.3
Wiendl, H.4
Becker, B.5
Walter, B.6
Majdic, O.7
Gajewski, T.F.8
Theobald, M.9
Andreesen, R.10
Mackensen, A.11
-
6
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, Ling V, Bowman MR, Carreno BM, Collins M, Wood CR, Honjo T: Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192: 1027-1034.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
7
-
-
84908031412
-
Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigenspecific T cells
-
Pen JJ, Keersmaecker BD, Heirman C, Corthals J, Liechtenstein T, Escors D, Thielemans K, Breckpot K: Interference with PD-L1/PD-1 co-stimulation during antigen presentation enhances the multifunctionality of antigenspecific T cells. Gene Ther 2014; 21: 262-271.
-
(2014)
Gene Ther
, vol.21
, pp. 262-271
-
-
Pen, J.J.1
Keersmaecker, B.D.2
Heirman, C.3
Corthals, J.4
Liechtenstein, T.5
Escors, D.6
Thielemans, K.7
Breckpot, K.8
-
8
-
-
0037307930
-
Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
-
Brown JA, Dorfman DM, Ma FR, Sullivan EL, Munoz O, Wood CR, Greenfield EA, Freeman GJ: Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production. J Immunol 2003; 170: 1257-1266.
-
(2003)
J Immunol
, vol.170
, pp. 1257-1266
-
-
Brown, J.A.1
Dorfman, D.M.2
Ma, F.R.3
Sullivan, E.L.4
Munoz, O.5
Wood, C.R.6
Greenfield, E.A.7
Freeman, G.J.8
-
9
-
-
5844264920
-
PDL2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K: PDL2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol 2001; 2: 261-268.
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
Greenfield, E.A.11
Bourque, K.12
-
10
-
-
18544380239
-
Tumor associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, Roche PC, Lu J, Zhu G, Tamada K, Lennon VA, Celis E, Chen L: Tumor associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med 2002; 8: 793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
Roche, P.C.7
Lu, J.8
Zhu, G.9
Tamada, K.10
Lennon, V.A.11
Celis, E.12
Chen, L.13
-
12
-
-
0037126021
-
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
-
Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N: Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci USA 2002; 99: 12293-12297.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12293-12297
-
-
Iwai, Y.1
Ishida, M.2
Tanaka, Y.3
Okazaki, T.4
Honjo, T.5
Minato, N.6
-
13
-
-
70349234325
-
B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders
-
Wilcox RA, Feldman AL, Wada DA, Yang ZZ, Comfere NI, Dong H, Kwon ED, Novak A, Markovic SN, Pittelkow MR, Witzig TE, Ansell SM: B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders. Blood 2012; 114: 2149-2158.
-
(2012)
Blood
, vol.114
, pp. 2149-2158
-
-
Wilcox, R.A.1
Feldman, A.L.2
Wada, D.A.3
Yang, Z.Z.4
Comfere, N.I.5
Dong, H.6
Kwon, E.D.7
Novak, A.8
Markovic, S.N.9
Pittelkow, M.R.10
Witzig, T.E.11
Ansell, S.M.12
-
14
-
-
84878458037
-
The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia
-
Brusa D, Serra S, Coscia M, Rossi D, D'Arena G, Laurenti L, Jaksic O, Fedele G, Inghirami G, Gaidano G, Malavasi F, Deaglio S: The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia. Haematologica 2013; 98: 953-963.
-
(2013)
Haematologica
, vol.98
, pp. 953-963
-
-
Brusa, D.1
Serra, S.2
Coscia, M.3
Rossi, D.4
D'Arena, G.5
Laurenti, L.6
Jaksic, O.7
Fedele, G.8
Inghirami, G.9
Gaidano, G.10
Malavasi, F.11
Deaglio, S.12
-
15
-
-
84859817335
-
Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia
-
Grzywnowicz M, Zaleska J, Mertens D, Tomczak W, Wlasiuk P, Kosior K, Piechnik A, Bojarska-Junak A, Dmoszynska A, Giannopoulos K: Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia. PloS One 2012; 7:e35178.
-
(2012)
PloS One
, vol.7
, pp. e35178
-
-
Grzywnowicz, M.1
Zaleska, J.2
Mertens, D.3
Tomczak, W.4
Wlasiuk, P.5
Kosior, K.6
Piechnik, A.7
Bojarska-Junak, A.8
Dmoszynska, A.9
Giannopoulos, K.10
-
16
-
-
45149100665
-
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 Guidelines
-
Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Dohner H, Hillmen P, Keating MP, Montserrat E, Rai KR, Kipps TJ: Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 Guidelines. Blood 2008; 111: 5446-5456.
-
(2008)
Blood
, vol.111
, pp. 5446-5456
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
Caligaris-Cappio, F.4
Dighiero, G.5
Dohner, H.6
Hillmen, P.7
Keating, M.P.8
Montserrat, E.9
Rai, K.R.10
Kipps, T.J.11
-
17
-
-
70350734809
-
The microenvironment in mature B-cell malignancies: A target for new treatment strategies
-
Burger JA, Ghia P, Rosenwald A, Caligaris-Cappio F: The microenvironment in mature B-cell malignancies: a target for new treatment strategies. Blood 2009; 144: 3367-3375.
-
(2009)
Blood
, vol.144
, pp. 3367-3375
-
-
Burger, J.A.1
Ghia, P.2
Rosenwald, A.3
Caligaris-Cappio, F.4
-
18
-
-
80054853285
-
B-cell receptor signaling in chronic lymphocytic leukemia
-
Stevenson BK, Krysov S, Davies AJ, Steele AJ, Packham G: B-cell receptor signaling in chronic lymphocytic leukemia. Blood 2011; 118: 4313-4320.
-
(2011)
Blood
, vol.118
, pp. 4313-4320
-
-
Stevenson, B.K.1
Krysov, S.2
Davies, A.J.3
Steele, A.J.4
Packham, G.5
-
19
-
-
84877080091
-
Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia
-
Wienster A: Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2012; 2012: 88-96.
-
(2012)
Hematology Am Soc Hematol Educ Program
, vol.2012
, pp. 88-96
-
-
Wienster, A.1
-
20
-
-
84875185728
-
Targeting pathological B cell receptor signalling in lymphoid malignancies
-
Young RM, Staudt LM: Targeting pathological B cell receptor signalling in lymphoid malignancies. Nat Rev Drug Discov 2013; 12: 229-243.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 229-243
-
-
Young, R.M.1
Staudt, L.M.2
-
21
-
-
84866152172
-
Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
-
Duhren-von Minden M, Ubelhart R, Schneider D, Wossning T, Bach MP, Buchner M, Hofmann D, Surova E, Follo M, Kohler F, Wardemann H, Zirlik K, Veelken H, Jumaa H: Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling. Nature 2012; 489: 309-312.
-
(2012)
Nature
, vol.489
, pp. 309-312
-
-
Duhren-Von Minden, M.1
Ubelhart, R.2
Schneider, D.3
Wossning, T.4
Bach, M.P.5
Buchner, M.6
Hofmann, D.7
Surova, E.8
Follo, M.9
Kohler, F.10
Wardemann, H.11
Zirlik, K.12
Veelken, H.13
Jumaa, H.14
-
22
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM: Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002; 99: 15524-15529.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
Bichi, R.4
Zupo, S.5
Noch, E.6
Aldler, H.7
Rattan, S.8
Keating, M.9
Rai, K.10
Rassenti, L.11
Kipps, T.12
Negrini, M.13
Bullrich, F.14
Croce, C.M.15
-
23
-
-
72949093335
-
From pathogenesis to treatment of chronic lymphocytic leukaemia
-
Zenz T, Mertens D, Kuppers R, Dohner H, Stilgenbauer S: From pathogenesis to treatment of chronic lymphocytic leukaemia. Nat Rev Cancer 2010; 10: 37-50.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 37-50
-
-
Zenz, T.1
Mertens, D.2
Kuppers, R.3
Dohner, H.4
Stilgenbauer, S.5
-
24
-
-
34447646310
-
Programmed death-1 ligand interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freemann GJ: Programmed death-1 ligand interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 2007; 27: 111-122.
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freemann, G.J.5
-
25
-
-
77957701558
-
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutical target for CT-011, a novel monoclonal anti-PD-1 antibody
-
Benson DM Jr, Bakan CE, Mishra A, Hofmeister CC, Efebera Y, Becknell B, Baiocchi RA, Zhang J, Yu J, Smith MK, Greenfield CN, Porcu P, Devine SM, Rotem-Yehudar R, Lozanski G, John C. Byrd JC, Michael A. Caligiuri MA: The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutical target for CT-011, a novel monoclonal anti-PD-1 antibody. Blood 2010; 116: 2286-2294.
-
(2010)
Blood
, vol.116
, pp. 2286-2294
-
-
Benson, D.M.1
Bakan, C.E.2
Mishra, A.3
Hofmeister, C.C.4
Efebera, Y.5
Becknell, B.6
Baiocchi, R.A.7
Zhang, J.8
Yu, J.9
Smith, M.K.10
Greenfield, C.N.11
Porcu, P.12
Devine, S.M.13
Rotem-Yehudar, R.14
Lozanski, G.15
John, C.16
Byrd, J.C.17
Michael, A.18
Caligiuri, M.A.19
-
26
-
-
33646422454
-
Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma
-
Yang ZZ, Novak AJ, Stenson MJ, Witzig TE, Ansell SM: Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma. Blood 2006; 107: 3639-3646.
-
(2006)
Blood
, vol.107
, pp. 3639-3646
-
-
Yang, Z.Z.1
Novak, A.J.2
Stenson, M.J.3
Witzig, T.E.4
Ansell, S.M.5
-
27
-
-
83055164370
-
Malignant B cells induce the conversion of CD4+CD25-T cells to regulatory T cells in B-cell non-Hodgkin lymphoma
-
Han Y, Wu J, Bi L, Xiong S, Gao S, Yin L, Jiang L, Chen CH, Yu K, Zhang S: Malignant B cells induce the conversion of CD4+CD25-T cells to regulatory T cells in B-cell non-Hodgkin lymphoma. PloS One 2011; 6:e28649.
-
(2011)
PloS One
, vol.6
, pp. e28649
-
-
Han, Y.1
Wu, J.2
Bi, L.3
Xiong, S.4
Gao, S.5
Yin, L.6
Jiang, L.7
Chen, C.H.8
Yu, K.9
Zhang, S.10
-
28
-
-
79957891364
-
PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cells/myeloma fusion vaccine
-
Rosenblatt J, Glotzbecker B, Mills H, Vasir B, Tzachanis D, Levine JD, Joyce RM, Wellenstein K, Keefe W, Schickler M, Rotem-Yehudar R, Kufe D: PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cells/myeloma fusion vaccine. J Immunother 2011; 34: 409-418.
-
(2011)
J Immunother
, vol.34
, pp. 409-418
-
-
Rosenblatt, J.1
Glotzbecker, B.2
Mills, H.3
Vasir, B.4
Tzachanis, D.5
Levine, J.D.6
Joyce, R.M.7
Wellenstein, K.8
Keefe, W.9
Schickler, M.10
Rotem-Yehudar, R.11
Kufe, D.12
-
29
-
-
43549115533
-
B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells
-
Azuma T, Yao S, Zhu G, Flies SJ, Chen L: B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells. Blood 2008; 111: 3635-3643.
-
(2008)
Blood
, vol.111
, pp. 3635-3643
-
-
Azuma, T.1
Yao, S.2
Zhu, G.3
Flies, S.J.4
Chen, L.5
-
30
-
-
84856515333
-
Expansion of a CD8+PD-1+ replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression
-
Nunes CT, Wong R, Mason M, Fegan C, Man S, Pepper C: Expansion of a CD8+PD-1+ replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression. Clin Cancer Res 2012; 18: 678-687.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 678-687
-
-
Nunes, C.T.1
Wong, R.2
Mason, M.3
Fegan, C.4
Man, S.5
Pepper, C.6
-
31
-
-
84923183950
-
Anti-PD-1-targeted therapies focusing on lymphatic malignancies: Biological rationale, clinical challenges and opportunities
-
Kedmi M, Avigdor A, Nagler A: Anti-PD-1-targeted therapies focusing on lymphatic malignancies: biological rationale, clinical challenges and opportunities. Acta Haematol 2015; 133: 129-135.
-
(2015)
Acta Haematol
, vol.133
, pp. 129-135
-
-
Kedmi, M.1
Avigdor, A.2
Nagler, A.3
-
32
-
-
4444317516
-
PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKC theta
-
Sheppard KA, Fitz LJ, Lee JM, Benander C, George JA, Wooters J, Qiu Y, Jussif JM, Carter LL, Wood CR, Chaudhary D: PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKC theta. FEBS Lett 2004; 574: 37-41.
-
(2004)
FEBS Lett
, vol.574
, pp. 37-41
-
-
Sheppard, K.A.1
Fitz, L.J.2
Lee, J.M.3
Benander, C.4
George, J.A.5
Wooters, J.6
Qiu, Y.7
Jussif, J.M.8
Carter, L.L.9
Wood, C.R.10
Chaudhary, D.11
-
33
-
-
13444270323
-
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
-
Hirano F, Kaneko K, Tamura H, Dong H, Wang S, Ichikawa M, Rietz C, Flies DB, Lau JS, Zhu G, Tamada K, Chen L: Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer Res 2005; 65: 1089-1096.
-
(2005)
Cancer Res
, vol.65
, pp. 1089-1096
-
-
Hirano, F.1
Kaneko, K.2
Tamura, H.3
Dong, H.4
Wang, S.5
Ichikawa, M.6
Rietz, C.7
Flies, D.B.8
Lau, J.S.9
Zhu, G.10
Tamada, K.11
Chen, L.12
-
34
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, Wolchok JD, Hersey P, Joseph RW, Weber JS, Dronca R, Gangadhar TC, Patnaik A, Zarour H, Joshua AM, Gergich K, Elassaiss-Schaap J, Algazi A, Mateus CH, Boasberg P, Tumeh PC, Chmielowski B, Ebbinghaus SW, Li XN, Kang SP, Ribas A: Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013; 369: 134-144.
-
(2013)
N Engl J Med
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
Wolchok, J.D.7
Hersey, P.8
Joseph, R.W.9
Weber, J.S.10
Dronca, R.11
Gangadhar, T.C.12
Patnaik, A.13
Zarour, H.14
Joshua, A.M.15
Gergich, K.16
Elassaiss-Schaap, J.17
Algazi, A.18
Mateus, C.H.19
Boasberg, P.20
Tumeh, P.C.21
Chmielowski, B.22
Ebbinghaus, S.W.23
Li, X.N.24
Kang, S.P.25
Ribas, A.26
more..
-
35
-
-
84902489577
-
The state of the art in nonsmall cell lung cancer immunotherapy
-
Seetharamu N: The state of the art in nonsmall cell lung cancer immunotherapy. Semin Thorac Cardiovasc Surg 2014; 26: 26-35.
-
(2014)
Semin Thorac Cardiovasc Surg
, vol.26
, pp. 26-35
-
-
Seetharamu, N.1
-
36
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M: Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366: 2443-2454.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
Horn, L.14
Drake, C.G.15
Pardoll, D.M.16
Chen, L.17
Sharfman, W.H.18
Anders, R.A.19
Taube, J.M.20
McMiller, T.L.21
Xu, H.22
Korman, A.J.23
Jure-Kunkel, M.24
Agrawal, S.25
McDonald, D.26
Kollia, G.D.27
Gupta, A.28
Wigginton, J.M.29
Sznol, M.30
more..
-
37
-
-
84899048777
-
Clinical activity, safety and biomarkers of PD-L1 blockade in non-small cell lung cancer (NSCLC): Additional analyses from a clinical study of the engineered antibody MPDL3280A (anti-PDL1)
-
Soria JC, Cruz C, Bahleda R, Delord JP, Horn L, Herbst RS, Gettinger S: Clinical activity, safety and biomarkers of PD-L1 blockade in non-small cell lung cancer (NSCLC): additional analyses from a clinical study of the engineered antibody MPDL3280A (anti-PDL1). Eur Cancer Congr 2013; 49:S798.
-
(2013)
Eur Cancer Congr
, vol.49
, pp. S798
-
-
Soria, J.C.1
Cruz, C.2
Bahleda, R.3
Delord, J.P.4
Horn, L.5
Herbst, R.S.6
Gettinger, S.7
|