Chemopreventive and therapeutic potentials of thymoquinone in HepG2 cells: Mechanistic perspectives

Journal of Natural Medicines

Volumn 69, Issue 3, 2015, Pages 313-323

  Elkhoely, Abeer ^a   Hafez, Hafez F ^b   Ashmawy, Abeer M ^b   Badary, Osama ^c   Abdelaziz, Ahmed ^b   Mostafa, Adel ^a   Shouman, Samia A ^b  

^a Helwan   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c African Union Organization St Abbassia   (Egypt)

Author keywords

Antitumor; Apoptosis; Cell cycle; Chemopreventive; HepG2; Thymoquinone

Indexed keywords

CYTOCHROME P450 1A1; GLUTATHIONE TRANSFERASE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; THYMOQUINONE; VASCULOTROPIN; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; CYP1A1 PROTEIN, HUMAN; GLUTATHIONE; LEUKOTRIENE-C4 SYNTHASE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BRAIN TUMOR CELL LINE; CANCER INHIBITION; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; G2 PHASE CELL CYCLE CHECKPOINT; HCT116 CELL LINE; HELA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; NONHUMAN; CELL CYCLE; CELL SURVIVAL; DRUG EFFECTS; DRUG SCREENING; GENETICS; IC50; LIVER NEOPLASMS; METABOLISM; TUMOR CELL LINE;

ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOQUINONES; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CHEMOPREVENTION; CYTOCHROME P-450 CYP1A1; DRUG SCREENING ASSAYS, ANTITUMOR; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HCT116 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84930765228     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-015-0895-7     Document Type: Article

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