Wogonin influences vascular permeability via Wnt/β-catenin pathway

Molecular Carcinogenesis

Volumn 54, Issue 7, 2015, Pages 501-512

  Song, Xiuming ^a   Zhou, Yuxin ^a   Zhou, Mi ^a   Huang, Yujie ^a   Li, Zhiyu ^a   You, Qidong ^a   Lu, Na ^a   Guo, Qinglong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Degradation; Vascular permeability; Wnt catenin; Wogonin

Indexed keywords

ACTIN; AXIN; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; LYMPHOID ENHANCER FACTOR 1; TRANSCRIPTION FACTOR 7; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN; WNT PROTEIN; WOGONIN; FLAVANONE DERIVATIVE; VASCULOTROPIN A;

ACTIN FILAMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BREAST CANCER CELL LINE; CELL ACTIVITY; CELL MIGRATION; CELLULAR SECRETION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UBIQUITINATION; UMBILICAL VEIN ENDOTHELIAL CELL; WNT SIGNALING PATHWAY; CAPILLARY PERMEABILITY; CELL HYPOXIA; CELL PROLIFERATION; CHEMISTRY; DOWN REGULATION; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; SCUTELLARIA; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TUMOR CELL LINE;

SCUTELLARIA BAICALENSIS;

CAPILLARY PERMEABILITY; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; FLAVANONES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PROTEOLYSIS; SCUTELLARIA; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WNT SIGNALING PATHWAY;

EID: 84930758528     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22093     Document Type: Article

References (35)

1. Schlingemann RO, van Hinsbergh VW. Role of vascular permeability factor/vascular endothelial growth factor in eye disease. Br J Ophthalmol 1997; 81:501-512.
2. Kaplan JD, Trulock EP, Anderson D.P, Schuster DJ. Pulmonary vascular permeability in interstitial lung disease. A positron emission tomographic study. Am Rev Respir Dis 1992; 145:1495-1498.
3. Weis SM. Vascular permeability in cardiovascular disease and cancer. Curr Opin Hematol 2008; 15:243-249.
4. Jain RK. Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy. Science 2005; 307:58-62.
5. Dejana E, Orsenigo MG, Lampugnani F. The role of adherens junctions and VE-cadherin in the control of vascular permeability. J Cell Sci 2008; 121:2115-2122.
6. Mazumdar J, O'Brien WT, Johnson RS, et al. O2 regulates stem cells through Wnt/beta-catenin signalling. Nat Cell Biol 2010; 12:1007-1013.
7. Jamieson C, Sharma M, Henderson BR. Henderson Wnt signaling from membrane to nucleus: beta-catenin caught in a loop. Int J Biochem Cell Biol 2012; 44:847-850.
8. Carayol NCY, Wang IK. Kalpha stabilizes cytosolic beta-catenin by inhibiting both canonical and non-canonical degradation pathways. Cell Signal 2006; 18:1941-1946.
9. Goodwin AM, Sullivan PA, D'Amore KM. Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Dev Dyn 2006; 235:3110-3120.
10. Mikels AJR. Nusse Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 2006; 4:e115.
11. Gao Z, Huang K, Yang H, Xu X. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochim Biophys Acta 1999; 1472:643-650.
12. You KM, Jong HP, Kim HG. Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants. Arch Pharm Res 1999; 22:18-24.
13. Lee WR, Shen SC, Lin HY, et al. Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease. Biochem Pharmacol 2002; 63:225-236.
14. Huang KF, Zhang GD, Huang Y, Diao YQ. Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway. Int Immunopharmacol 2012; 12:334-341.
15. Zhang K, Guo QL, You QD, et al. Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. Cancer Sci 2008; 99:689-695.
16. Hui KM, Huen MS, Wang HY, et al. Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochem Pharmacol 2002; 64:1415-1424.
17. Jaffe EA, Nachman RL, Becker CR, Minick CG. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52:2745-2756.
18. Li C, Lu N, Qi Q, et al. Gambogic acid inhibits tumor cell adhesion by suppressing integrin beta1 and membrane lipid rafts-associated integrin signaling pathway. Biochem Pharmacol 2011; 82:1873-1883.
19. Eum SY, Lee YW, Hennig M, Toborek B. VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells. Exp Cell Res 2004; 296:231-244.
20. Choi YS, Choi HJ, Min JK, et al. Interleukin-33 induces angiogenesis and vascular permeability through ST2/TRAF6-mediated endothelial nitric oxide production. Blood 2009; 114:3117-3126.
21. Rong JJ, Hu R, Qi Q, et al. Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53. Cancer Lett 2009; 284:102-112.
22. Steel R, Doherty JP, Buzzard K, et al. Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1. J Biol Chem 2004; 279:51490-51499.
23. Rehbein M, Kindler S, Horke D, Richter S. Two trans-acting rat-brain proteins, MARTA1 and MARTA2, interact specifically with the dendritic targeting element in MAP2 mRNAs. Brain Res Mol Brain Res 2000; 79:192-201.
24. Lu Z, Lu N, Li C, et al. Oroxylin A inhibits matrix metalloproteinase-2/9 expression and activation by up-regulating tissue inhibitor of metalloproteinase-2 and suppressing the ERK1/2 signaling pathway. Toxicol Lett 2012; 209:211-220.
25. Gu H, Wang X, Rao S, et al. Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells. Mol Cancer Ther 2008; 7:3298-3305.
26. Sakai H, Kozutsumi Y, Goto K, Chiba M, Misawa Y. Functional importance of the cytoskeletal protein in acetylcholine-induced contraction of rat bronchial smooth muscle. J Smooth Muscle Res 2009; 45:97-108.
27. Dejana E. The role of wnt signaling in physiological and pathological angiogenesis. Circ Res 2010; 107:943-952.
28. Easwaran V, Lee SH, Inge L, et al. beta-Catenin regulates vascular endothelial growth factor expression in colon cancer. Cancer Res 2003; 63:3145-3153.
29. Dvorak HF. Discovery of vascular permeability factor (VPF). Exp Cell Res 2006; 312:522-526.
30. Min JK, Cho YL, Choi JH, et al. Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: Impaired permeability and angiogenesis in eNOS-deficient mice. Blood 2007; 109:1495-1502.
31. Sun H, Jiang YJ, Yu QS, Luo JW, Zou CC. The effect of Li+ on GSK-3 inhibition: Molecular dynamics simulation. J Mol Model 2011; 17:377-381.
32. Lim JH, Chun JW, Park YS. Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin. Cancer Res 2008; 68:5177-5184.
33. Genetos DC, Toupadakis CA, Raheja LF, et al. Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts. J Cell Biochem 2010; 110:457-467.
34. He L, Lu N, Dai Q, et al. Wogonin induced G1 cell cycle arrest by regulating Wnt/beta-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. Toxicology 2013; 312C:36-47.
35. Wang Y, Zhang Y, Qian C, et al. GSK3beta/beta-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. Toxicol Lett 2013; 222:212-223.