Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

Nature Medicine

Volumn 21, Issue 6, 2015, Pages 601-609

  Schiffer, Mario ^a,b   Teng, Beina ^a   Gu, Changkyu ^c   Shchedrina, Valentina A ^c   Kasaikina, Marina ^c   Pham, Vincent A ^c   Hanke, Nils ^a   Rong, Song ^a   Gueler, Faikah ^a   Schroder, Patricia ^a,b   Tossidou, Irini ^a   Park, Joon Keun ^a   Staggs, Lynne ^a,b   Haller, Hermann ^a,b   Erschow, Sergej ^a   Hilfiker Kleiner, Denise ^a   Wei, Changli ^d   Chen, Chuang ^d   Tardi, Nicholas ^d   Hakroush, Samy ^e   Selig, Martin K ^c   Vasilyev, Aleksandr ^f   Merscher, Sandra ^g   Reiser, Jochen ^d   Sever, Sanja ^c   more..

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b MOUNT DESERT ISLAND BIOLOGICAL LABORATORY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d RUSH UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^f NYIT COM ^*  (United States)

^g UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO N [3 [2 CYANO 3 (3,4,5 TRIHYDROXYPHENYL)ACRYLOYLAMINO]PROPYL] 3 (3,4,5 TRIHYDROXYPHENYL)ACRYLAMIDE; ACRYLAMIDE DERIVATIVE; ALBUMIN; COLLAGEN TYPE 4; CREATININE; DYNAMIN; HYDROLASE INHIBITOR; PROTECTIVE AGENT; UNCLASSIFIED DRUG; URINARY TRACT AGENT; ACRYLAMIDE; BIS-T-23 COMPOUND; COUMARIC ACID; CYANOACRYLATE DERIVATIVE;

ACTIN FILAMENT; ANALYTICAL PARAMETERS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CELL ULTRASTRUCTURE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG TARGETING; EMBRYO; GLOMERULUS FILTRATION RATE; KIDNEY HYPERTROPHY; KIDNEY PLASMA FLOW; MALE; MOUSE; NONHUMAN; OLIGOMERIZATION; PODOCYTE; PRIORITY JOURNAL; PROTEINURIA; RAT; RENAL PROTECTION; RENAL SYSTEM PARAMETERS; SINGLE DRUG DOSE; URINE ALBUMIN CREATININE RATIO; ANIMAL; CHEMISTRY; DRUG EFFECTS; GLOMERULUS; HUMAN; METABOLISM; PATHOLOGY; RENAL INSUFFICIENCY, CHRONIC; ULTRASTRUCTURE; ZEBRA FISH;

ANIMALIA;

ACRYLAMIDE; ACTIN CYTOSKELETON; ANIMALS; COUMARIC ACIDS; CYANOACRYLATES; DYNAMINS; HUMANS; KIDNEY GLOMERULUS; MICE; MODELS, ANIMAL; PODOCYTES; PROTEINURIA; RENAL INSUFFICIENCY, CHRONIC; ZEBRAFISH;

EID: 84930752224     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3843     Document Type: Article

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