Small molecule inhibitors of dynamin I GTPase activity: Development of dimeric tyrphostins

Journal of Medicinal Chemistry

Volumn 48, Issue 24, 2005, Pages 7781-7788

  Hill, Timothy ^a   Odell, Luke R ^a   Edwards, Jennifer K ^a   Graham, Mark E ^b   McGeachie, Andrew B ^b   Rusak, Jenny ^b   Quan, Annie ^b   Abagyan, Ruben ^c   Scott, Janet L ^d   Robinson, Phillip J ^b   McCluskey, Adam ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO 3 (3,4 DIHYDROXYPHENYL)THIOACRYLAMIDE; 2 CYANO N [3 [2 CYANO 3 (3,4 DIHYDROXY 4 METHOXYPHENYL)ACRYLOYLAMINO]ETHYL] 3 (3,4 DIHYDROXY 5 METHOXYPHENYL)ACRYLAMIDE; 2 CYANO N [3 [2 CYANO 3 (3,4 DIHYDROXY 5 METHOXYPHENYL)ACRYLOYLAMINO]BUTYL] 3 (3,4 DIHYDROXY 5 METHOXYPHENYL)ACRYLAMIDE; 2 CYANO N [3 [2 CYANO 3 (3,4,5 TRIHYDROXYPHENYL)ACRYLOYLAMINO]ETHYL] 3 (3,4,5 TRIHYDROXYPHENYL)ACRYLAMIDE; ALKYL GROUP; CATECHOL ACRYLAMIDE; CATECHOL ACRYLAMIDE 3 METHYL ETHER; CATECHOL ACRYLAMIDE BUTYL ESTER; CATECHOL ACRYLAMIDE ETHYL ESTER; DIMER; DYNAMIN; ENZYME INHIBITOR; ETHER DERIVATIVE; METHYL GROUP; PHENOL DERIVATIVE; PROPANE; TYRPHOSTIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; BRAIN; DIMERIZATION; DYNAMIN I; SHEEP; STRUCTURE-ACTIVITY RELATIONSHIP; TYRPHOSTINS;

EID: 28144443754     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm040208l     Document Type: Article

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