메뉴 건너뛰기




Volumn 46, Issue 10, 2014, Pages 877-884

Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin

Author keywords

Fucoxanthin; G0 G1 phase; Human bladder cancer T24 cells; Mortalin; P53

Indexed keywords

FUCOXANTHIN; HEAT SHOCK PROTEIN 70; MORTALIN; PROTEIN P21; XANTHOPHYLL;

EID: 84930729174     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmu080     Document Type: Article
Times cited : (46)

References (49)
  • 2
    • 84859429759 scopus 로고    scopus 로고
    • Prognostic factors for upper urinary tract urothelial carcinoma after nephroureterectomy
    • Kuroda K, Asakuma J, Horiguchi A, Tasaki S, Yoshii H, Sato A and Ito K, et al. Prognostic factors for upper urinary tract urothelial carcinoma after nephroureterectomy. Urol Int 2012, 88:225-231.
    • (2012) Urol Int , vol.88 , pp. 225-231
    • Kuroda, K.1    Asakuma, J.2    Horiguchi, A.3    Tasaki, S.4    Yoshii, H.5    Sato, A.6    Ito, K.7
  • 4
    • 39149083413 scopus 로고    scopus 로고
    • Prognostic value of MET, RON and histoprognostic factors for urothelial carcinoma in the upper urinary tract
    • Comperat E, Roupret M, Chartier-Kastler E, Bitker MO, Richard F, Camparo P and Capron F, et al. Prognostic value of MET, RON and histoprognostic factors for urothelial carcinoma in the upper urinary tract. J Urol 2008, 179:868-872.
    • (2008) J Urol , vol.179 , pp. 868-872
    • Comperat, E.1    Roupret, M.2    Chartier-Kastler, E.3    Bitker, M.O.4    Richard, F.5    Camparo, P.6    Capron, F.7
  • 5
    • 84890787048 scopus 로고    scopus 로고
    • Impact of bladder neck involvement on progression in patients with primary non-muscle invasive bladder cancer: A prospective validation study
    • Kobayashi S, Fujii Y, Koga F, Yokoyama M, Ishioka J, Matsuoka Y and Numao N, et al. Impact of bladder neck involvement on progression in patients with primary non-muscle invasive bladder cancer: a prospective validation study. Urol Oncol 2014, 32:29-36.
    • (2014) Urol Oncol , vol.32 , pp. 29-36
    • Kobayashi, S.1    Fujii, Y.2    Koga, F.3    Yokoyama, M.4    Ishioka, J.5    Matsuoka, Y.6    Numao, N.7
  • 6
    • 84890795489 scopus 로고    scopus 로고
    • Incidence and location of lymph node metastases in patients undergoing radical cystectomy for clinical non-muscle invasive bladder cancer: Results from a prospective lymph node mapping study
    • Bruins HM, Skinner EC, Dorin RP, Ahmadi H, Djaladat H, Miranda G and Cai J, et al. Incidence and location of lymph node metastases in patients undergoing radical cystectomy for clinical non-muscle invasive bladder cancer: results from a prospective lymph node mapping study. Urol Oncol 2014, 32:13-29.
    • (2014) Urol Oncol , vol.32 , pp. 13-29
    • Bruins, H.M.1    Skinner, E.C.2    Dorin, R.P.3    Ahmadi, H.4    Djaladat, H.5    Miranda, G.6    Cai, J.7
  • 7
    • 84884240429 scopus 로고    scopus 로고
    • Current intravesical therapy for non-muscle invasive bladder cancer
    • van Lingen AV and Witjes JA. Current intravesical therapy for non-muscle invasive bladder cancer. Expert Opin Biol Th 2013, 13:1371-1385.
    • (2013) Expert Opin Biol Th , vol.13 , pp. 1371-1385
    • Van Lingen, A.V.1    Witjes, J.A.2
  • 8
    • 84887503110 scopus 로고    scopus 로고
    • Treatment of bacillus Calmette-Guerin refractory non-muscle invasive bladder cancer
    • Turker P and Turkeri L. Treatment of bacillus Calmette-Guerin refractory non-muscle invasive bladder cancer. Arch Espan Urol 2013, 66:833-840.
    • (2013) Arch Espan Urol , vol.66 , pp. 833-840
    • Turker, P.1    Turkeri, L.2
  • 9
  • 10
    • 84888314282 scopus 로고    scopus 로고
    • Non-muscle invasive bladder cancer with multiple bone metastasis without local invasion: A case report
    • Sasaki Y, Oi H, Oyama T, Kagawa J, Komori M, Senzaki T and Fukawa T, et al. Non-muscle invasive bladder cancer with multiple bone metastasis without local invasion: a case report. Acta Urol Jpn 2013, 59:669-672.
    • (2013) Acta Urol Jpn , vol.59 , pp. 669-672
    • Sasaki, Y.1    Oi, H.2    Oyama, T.3    Kagawa, J.4    Komori, M.5    Senzaki, T.6    Fukawa, T.7
  • 11
    • 0038692733 scopus 로고    scopus 로고
    • Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and retinol efficacy trial
    • Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A and Keogh JP, et al. Risk factors for lung cancer and for intervention effects in CARET, the beta-carotene and retinol efficacy trial. J Natl Cancer Inst 1996, 88:1550-1559.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1550-1559
    • Omenn, G.S.1    Goodman, G.E.2    Thornquist, M.D.3    Balmes, J.4    Cullen, M.R.5    Glass, A.6    Keogh, J.P.7
  • 12
    • 14644445985 scopus 로고    scopus 로고
    • Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells
    • Kotake-Nara E, Asai A and Nagao A. Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells. Cancer Lett 2005, 220:75-84.
    • (2005) Cancer Lett , vol.220 , pp. 75-84
    • Kotake-Nara, E.1    Asai, A.2    Nagao, A.3
  • 13
    • 7744240624 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARgamma ligand, troglitazone, on colon cancer cells
    • Hosokawa M, Kudo M, Maeda H, Kohno H, Tanaka T and Miyashita K. Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPARgamma ligand, troglitazone, on colon cancer cells. Biochim Biophys Acta 2004, 1675:113-119.
    • (2004) Biochim Biophys Acta , vol.1675 , pp. 113-119
    • Hosokawa, M.1    Kudo, M.2    Maeda, H.3    Kohno, H.4    Tanaka, T.5    Miyashita, K.6
  • 14
    • 77956181267 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway
    • Kim KN, Heo SJ, Kang SM, Ahn G and Jeon YJ. Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway. Toxicol In Vitro 2010, 24:1648-1654.
    • (2010) Toxicol in Vitro , vol.24 , pp. 1648-1654
    • Kim, K.N.1    Heo, S.J.2    Kang, S.M.3    Ahn, G.4    Jeon, Y.J.5
  • 15
    • 84863032179 scopus 로고    scopus 로고
    • Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174 T cells
    • Liu CL, Lim YP and Hu ML. Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174 T cells. Mar. Drugs 2012, 10:242-257.
    • (2012) Mar. Drugs , vol.10 , pp. 242-257
    • Liu, C.L.1    Lim, Y.P.2    Hu, M.L.3
  • 16
    • 84858782415 scopus 로고    scopus 로고
    • Fucoxanthin induces GADD45A expression and G1 arrest with SAPK/JNK activation in LNCap human prostate cancer cells
    • Satomi Y. Fucoxanthin induces GADD45A expression and G1 arrest with SAPK/JNK activation in LNCap human prostate cancer cells. Anticancer Res 2012, 32:807-813.
    • (2012) Anticancer Res , vol.32 , pp. 807-813
    • Satomi, Y.1
  • 17
    • 84865654040 scopus 로고    scopus 로고
    • Isolation of fucoxanthin from edible brown algae by microwave-assisted extraction coupled with high-speed countercurrent chromatography
    • Xiao X, Si X, Yuan Z, Xu X and Li G. Isolation of fucoxanthin from edible brown algae by microwave-assisted extraction coupled with high-speed countercurrent chromatography. J Sep. Sci 2012, 35:2313-2317.
    • (2012) J Sep. Sci , vol.35 , pp. 2313-2317
    • Xiao, X.1    Si, X.2    Yuan, Z.3    Xu, X.4    Li, G.5
  • 18
    • 58149350379 scopus 로고    scopus 로고
    • Potential chemoprevention effect of dietary fucoxanthin on urinary bladder cancer EJ-1 cell line
    • Zhang Z, Zhang P, Hamada M, Takahashi S, Xing G, Liu J and Sugiura N. Potential chemoprevention effect of dietary fucoxanthin on urinary bladder cancer EJ-1 cell line. Oncol Rep 2008, 20:1099-1103.
    • (2008) Oncol Rep , vol.20 , pp. 1099-1103
    • Zhang, Z.1    Zhang, P.2    Hamada, M.3    Takahashi, S.4    Xing, G.5    Liu, J.6    Sugiura, N.7
  • 19
    • 0020677746 scopus 로고
    • Identity of some human bladder cancer cell lines
    • O'Toole CM PS, Hepburn P and Franks LM. Identity of some human bladder cancer cell lines. Nature 1983, 5899:429-430.
    • (1983) Nature , vol.5899 , pp. 429-430
    • O'Toole, C.M.P.S.1    Hepburn, P.2    Franks, L.M.3
  • 20
    • 0027109075 scopus 로고
    • Cancer - P53, Guardian of the Genome
    • Lane DP. Cancer - P53, Guardian of the Genome. Nature 1992, 358:15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 21
    • 0033992478 scopus 로고    scopus 로고
    • P53 and human cancer: The first ten thousand mutations
    • Hainaut P and Hollstein M. p53 and human cancer: The first ten thousand mutations. Adv Cancer Res 2000, 77:81-137.
    • (2000) Adv Cancer Res , vol.77 , pp. 81-137
    • Hainaut, P.1    Hollstein, M.2
  • 22
    • 0036260527 scopus 로고    scopus 로고
    • Does p53 affect organismal aging?
    • Donehower LA. Does p53 affect organismal aging? J Cell Physiol 2002, 192:23-33.
    • (2002) J Cell Physiol , vol.192 , pp. 23-33
    • Donehower, L.A.1
  • 23
    • 0034717014 scopus 로고    scopus 로고
    • Death signal-induced localization of p53 protein to mitochondria-a potential role in apoptotic signaling
    • Marchenko ND, Zaika A and Moll UM. Death signal-induced localization of p53 protein to mitochondria-a potential role in apoptotic signaling. J Biol Chem 2000, 275:16202-16212.
    • (2000) J Biol Chem , vol.275 , pp. 16202-16212
    • Marchenko, N.D.1    Zaika, A.2    Moll, U.M.3
  • 24
    • 33847651284 scopus 로고    scopus 로고
    • Three faces of mortalin: A housekeeper, guardian and killer
    • Kaul SC, Deocaris CC and Wadhwa R. Three faces of mortalin: a housekeeper, guardian and killer. Exp Gerontol 2007, 42:263-274.
    • (2007) Exp Gerontol , vol.42 , pp. 263-274
    • Kaul, S.C.1    Deocaris, C.C.2    Wadhwa, R.3
  • 25
    • 84887037147 scopus 로고    scopus 로고
    • Molecular interactions of Bcl-2 and Bcl-xL with mortalin: Identification and functional characterization
    • Saxena N, Katiyar SP, Liu Y, Grover A, Gao R, Sundar D and Kaul SC, et al. Molecular interactions of Bcl-2 and Bcl-xL with mortalin: identification and functional characterization. Biosci Rep 2013, 33:797-806.
    • (2013) Biosci Rep , vol.33 , pp. 797-806
    • Saxena, N.1    Katiyar, S.P.2    Liu, Y.3    Grover, A.4    Gao, R.5    Sundar, D.6    Kaul, S.C.7
  • 26
    • 27444442414 scopus 로고    scopus 로고
    • Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60
    • Wadhwa R, Takano S, Kaur K, Aida S, Yaguchi T, Kaul Z and Hirano T, et al. Identification and characterization of molecular interactions between mortalin/mtHsp70 and HSP60. Biochem J 2005, 391:185-190.
    • (2005) Biochem J , vol.391 , pp. 185-190
    • Wadhwa, R.1    Takano, S.2    Kaur, K.3    Aida, S.4    Yaguchi, T.5    Kaul, Z.6    Hirano, T.7
  • 28
    • 0029657909 scopus 로고    scopus 로고
    • G0/G1 growth arrest mediated by a region encompassing the basic leucine zipper (bZIP) domain of the Epstein-Barr virus transactivator Zta
    • Cayrol C and Flemington E. G0/G1 growth arrest mediated by a region encompassing the basic leucine zipper (bZIP) domain of the Epstein-Barr virus transactivator Zta. J Biol Chem 1996, 271:31799-31802.
    • (1996) J Biol Chem , vol.271 , pp. 31799-31802
    • Cayrol, C.1    Flemington, E.2
  • 29
    • 0030849742 scopus 로고    scopus 로고
    • Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs
    • Tanaka T, Knapp D and Nasmyth K. Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Cell 1997, 90:649-660.
    • (1997) Cell , vol.90 , pp. 649-660
    • Tanaka, T.1    Knapp, D.2    Nasmyth, K.3
  • 30
    • 0033048814 scopus 로고    scopus 로고
    • The apoptosis cascade-morphological and immunohistochemical methods for its visualization
    • Huppertz B, Frank HG and Kaufmann P. The apoptosis cascade-morphological and immunohistochemical methods for its visualization. Anat Embryol 1999, 200:1-18.
    • (1999) Anat Embryol , vol.200 , pp. 1-18
    • Huppertz, B.1    Frank, H.G.2    Kaufmann, P.3
  • 31
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997, 88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 32
    • 79955827220 scopus 로고    scopus 로고
    • Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy
    • Lu WJ, Lee NP, Kaul SC, Lan F, Poon RT, Wadhwa R and Luk JM. Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy. Cell Death Differ 2011, 18:1046-1056.
    • (2011) Cell Death Differ , vol.18 , pp. 1046-1056
    • Lu, W.J.1    Lee, N.P.2    Kaul, S.C.3    Lan, F.4    Poon, R.T.5    Wadhwa, R.6    Luk, J.M.7
  • 33
    • 80052036411 scopus 로고    scopus 로고
    • Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin
    • Lu WJ, Lee NP, Kaul SC, Lan F, Poon RT, Wadhwa R and Luk JM. Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin. Int J Cancer 2011, 129:1806-1814.
    • (2011) Int J Cancer , vol.129 , pp. 1806-1814
    • Lu, W.J.1    Lee, N.P.2    Kaul, S.C.3    Lan, F.4    Poon, R.T.5    Wadhwa, R.6    Luk, J.M.7
  • 34
    • 27944450796 scopus 로고    scopus 로고
    • Fucoxanthin induces cell cycle arrest at G0/G1 phase in human colon carcinoma cells through up-regulation of p21WAF1/Cip1
    • Das SK, Hashimoto T, Shimizu K, Yoshida T, Sakai T, Sowa Y and Komoto A, et al. Fucoxanthin induces cell cycle arrest at G0/G1 phase in human colon carcinoma cells through up-regulation of p21WAF1/Cip1. Biochim Biophys Acta 2005, 1726:328-335.
    • (2005) Biochim Biophys Acta , vol.1726 , pp. 328-335
    • Das, S.K.1    Hashimoto, T.2    Shimizu, K.3    Yoshida, T.4    Sakai, T.5    Sowa, Y.6    Komoto, A.7
  • 35
    • 84887328958 scopus 로고    scopus 로고
    • Essential role of autophagy in fucoxanthin-induced cytotoxicity to human epithelial cervical cancer HeLa cells
    • Hou LL, Gao C, Chen L, Hu GQ and Xie SQ. Essential role of autophagy in fucoxanthin-induced cytotoxicity to human epithelial cervical cancer HeLa cells. Acta Pharmacol Sin 2013, 34:1403-1410.
    • (2013) Acta Pharmacol Sin , vol.34 , pp. 1403-1410
    • Hou, L.L.1    Gao, C.2    Chen, L.3    Hu, G.Q.4    Xie, S.Q.5
  • 36
    • 22144457954 scopus 로고    scopus 로고
    • Understanding and modulating cyclin-dependent kinase inhibitor specificity: Molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors
    • Rossi KA, Markwalder JA, Seitz SP, Chang CH, Cox S, Boisclair MD and Brizuela L, et al. Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors. J Comput Aid Mol Des 2005, 19:111-122.
    • (2005) J Comput Aid Mol Des , vol.19 , pp. 111-122
    • Rossi, K.A.1    Markwalder, J.A.2    Seitz, S.P.3    Chang, C.H.4    Cox, S.5    Boisclair, M.D.6    Brizuela, L.7
  • 37
    • 79551508635 scopus 로고    scopus 로고
    • Inhibition of Smad3 activity by cyclin D-CDK4 and cyclin E-CDK2 in breast cancer cells
    • Liu F. Inhibition of Smad3 activity by cyclin D-CDK4 and cyclin E-CDK2 in breast cancer cells. Cell Cycle 2011, 10:186.
    • (2011) Cell Cycle , vol.10 , pp. 186
    • Liu, F.1
  • 38
    • 54249162366 scopus 로고    scopus 로고
    • Norsolorinic acid inhibits proliferation of T24 human bladder cancer cells by arresting the cell cycle at the G0/G1 phase and inducing a Fas/membrane-bound Fas ligandmediated apoptotic pathway
    • Wang CC, Chiang YM, Kuo PL, Chang JK and Hsu YL. Norsolorinic acid inhibits proliferation of T24 human bladder cancer cells by arresting the cell cycle at the G0/G1 phase and inducing a Fas/membrane-bound Fas ligandmediated apoptotic pathway. Clin Exp Pharmacol P 2008, 35:1301-1308.
    • (2008) Clin Exp Pharmacol P , vol.35 , pp. 1301-1308
    • Wang, C.C.1    Chiang, Y.M.2    Kuo, P.L.3    Chang, J.K.4    Hsu, Y.L.5
  • 39
    • 70350134708 scopus 로고    scopus 로고
    • Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication
    • Liu C-L, Huang Y-S, Hosokawa M, Miyashita K and Hu M-L. Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication. Chem-Biol Interact 2009, 182:165-172.
    • (2009) Chem-biol Interact , vol.182 , pp. 165-172
    • Liu, C.-L.1    Huang, Y.-S.2    Hosokawa, M.3    Miyashita, K.4    Hu, M.-L.5
  • 42
    • 57349152305 scopus 로고    scopus 로고
    • Antiadult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol
    • Ishikawa C, Tafuku S, Kadekaru T, Sawada S, Tomita M, Okudaira T and Nakazato T, et al. Antiadult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. Intl J Cancer 2008, 123:2702-2712.
    • (2008) Intl J Cancer , vol.123 , pp. 2702-2712
    • Ishikawa, C.1    Tafuku, S.2    Kadekaru, T.3    Sawada, S.4    Tomita, M.5    Okudaira, T.6    Nakazato, T.7
  • 43
    • 78649629110 scopus 로고    scopus 로고
    • Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas
    • Yamamoto K, Ishikawa C, Katano H, Yasumoto T and Mori N. Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas. Cancer Lett 2011, 300:225-234.
    • (2011) Cancer Lett , vol.300 , pp. 225-234
    • Yamamoto, K.1    Ishikawa, C.2    Katano, H.3    Yasumoto, T.4    Mori, N.5
  • 44
    • 70349904741 scopus 로고    scopus 로고
    • Single and repeated oral dose toxicity study of fucoxanthin (FX), a marine carotenoid, in mice
    • Beppu F, Niwano Y, Tsukui T, Hosokawa M and Miyashita K. Single and repeated oral dose toxicity study of fucoxanthin (FX), a marine carotenoid, in mice. J Toxicol Sci 2009, 34:501-510.
    • (2009) J Toxicol Sci , vol.34 , pp. 501-510
    • Beppu, F.1    Niwano, Y.2    Tsukui, T.3    Hosokawa, M.4    Miyashita, K.5
  • 45
    • 79960164495 scopus 로고    scopus 로고
    • Bacterial reverse mutation test and micronucleus test of fucoxanthin oil from microalgae
    • Iio K, Okada Y and Ishikura M. Bacterial reverse mutation test and micronucleus test of fucoxanthin oil from microalgae. J Food Hyg Soc Jpn 2011, 52:190-193.
    • (2011) J Food Hyg Soc Jpn , vol.52 , pp. 190-193
    • Iio, K.1    Okada, Y.2    Ishikura, M.3
  • 46
    • 0035159152 scopus 로고    scopus 로고
    • Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-2 human intestinal cells
    • Sugawara T, Kushiro M, Zhang H, Nara E, Ono H and Nagao A. Lysophosphatidylcholine enhances carotenoid uptake from mixed micelles by Caco-2 human intestinal cells. J Nutr 2001, 131:2921-2927.
    • (2001) J Nutr , vol.131 , pp. 2921-2927
    • Sugawara, T.1    Kushiro, M.2    Zhang, H.3    Nara, E.4    Ono, H.5    Nagao, A.6
  • 47
    • 77958123742 scopus 로고    scopus 로고
    • Keto-carotenoids are the major metabolites of dietary lutein and fucoxanthin in mouse tissues
    • Yonekura L, Kobayashi M, Terasaki M and Nagao A. Keto-carotenoids are the major metabolites of dietary lutein and fucoxanthin in mouse tissues. J Nutr 2010, 140:1824-1831.
    • (2010) J Nutr , vol.140 , pp. 1824-1831
    • Yonekura, L.1    Kobayashi, M.2    Terasaki, M.3    Nagao, A.4
  • 48
    • 77952615626 scopus 로고    scopus 로고
    • Fucoxanthin induces apoptosis in osteoclast-like cells differentiated from RAW264.7 cells
    • Das SK, Ren R, Hashimoto T and Kanazawa K. Fucoxanthin induces apoptosis in osteoclast-like cells differentiated from RAW264.7 cells. J Agric Food Chem 2010, 58:6090-6095.
    • (2010) J Agric Food Chem , vol.58 , pp. 6090-6095
    • Das, S.K.1    Ren, R.2    Hashimoto, T.3    Kanazawa, K.4
  • 49
    • 84897430074 scopus 로고    scopus 로고
    • Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells
    • Sane S, Abdullah A, Boudreau DA, Autenried RK, Gupta BK, Wang X and Wang H, et al. Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells. Cell Death Dis 2014, 5:e1118.
    • (2014) Cell Death Dis , vol.5 , pp. e1118
    • Sane, S.1    Abdullah, A.2    Boudreau, D.A.3    Autenried, R.K.4    Gupta, B.K.5    Wang, X.6    Wang, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.