Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Savard, Alexandre ^a   Brochu, Marie Elsa ^a   Chevin, Mathilde ^a   Guiraut, Clémence ^a   Grbic, Djordje ^a   Sébire, Guillaume ^a,b  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Cerebral palsy; Chemokines; Hypoxia ischemia; Interleukin 1; Matrix metalloproteinase 9; Necroptosis; Neonatal encephalopathy

Indexed keywords

BINDING PROTEIN; CASPASE 3; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RECEPTOR INTERACTING PROTEIN 3; UNCLASSIFIED DRUG; GLIAL FIBRILLARY ACIDIC PROTEIN; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RECEPTOR-INTERACTING PROTEIN 3, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DISEASE; BRAIN HYPOXIA; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBRAL PALSY; CONTROLLED STUDY; CORPUS STRIATUM; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FOREBRAIN; GLIA CELL; IN SITU HYBRIDIZATION; MACROPHAGE; NECROPTOSIS; NEOCORTEX; NEONATAL ENCEPHALOPATHY; NERVE CELL MEMBRANE; NERVOUS SYSTEM INFLAMMATION; NEUROTOXICITY; NEUTROPHIL CHEMOTAXIS; NEWBORN; NEWBORN DISEASE; NONHUMAN; RAT; WHITE MATTER; AGE; ANIMAL; BRAIN DISEASES; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENETICS; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNOLOGY; LEWIS RAT; METABOLISM; MOTOR ACTIVITY; NERVE CELL; PATHOLOGY; STEREOTYPY;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BRAIN DISEASES; CASPASE 3; CEREBRAL PALSY; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPOXIA-ISCHEMIA, BRAIN; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MATRIX METALLOPROTEINASE 9; MOTOR ACTIVITY; NEURONS; RATS; RATS, INBRED LEW; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; STEREOTYPED BEHAVIOR;

EID: 84930672720     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0330-8     Document Type: Article

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