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Volumn 6, Issue , 2015, Pages

A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

EID: 84930667824     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8060     Document Type: Article
Times cited : (111)

References (58)
  • 1
    • 59149099759 scopus 로고    scopus 로고
    • The 10-year post-trial follow-up of the United Kingdom Prospective Diabetes Study (UKPDS): Cardiovascular observations in context
    • Gore, M. O. & McGuire, D. K. The 10-year post-trial follow-up of the United Kingdom Prospective Diabetes Study (UKPDS): Cardiovascular observations in context. Diab. Vasc. Dis. Res. 6, 53-55 (2009).
    • (2009) Diab. Vasc. Dis. Res. , vol.6 , pp. 53-55
    • Gore, M.O.1    McGuire, D.K.2
  • 2
    • 77953821528 scopus 로고    scopus 로고
    • Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies
    • The Emerging Risk Factors Collaboration. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies. Lancet 375, 2215-2222 (2010).
    • (2010) Lancet , vol.375 , pp. 2215-2222
  • 3
    • 54349095358 scopus 로고    scopus 로고
    • Management of cardiovascular disease in patients with diabetes: The 2008 Canadian Diabetes Association guidelines
    • Bhattacharyya, O. K., Shah, B. R. & Booth, G. L. Management of cardiovascular disease in patients with diabetes: The 2008 Canadian Diabetes Association guidelines. Can. Med. Assoc. J. 179, 920-926 (2008).
    • (2008) Can. Med. Assoc. J. , vol.179 , pp. 920-926
    • Bhattacharyya, O.K.1    Shah, B.R.2    Booth, G.L.3
  • 4
    • 0032902850 scopus 로고    scopus 로고
    • The relationship between glucose and incident cardiovascular events A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years
    • Coutinho, M., Gerstein, H. C., Wang, Y. & Yusuf, S. The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care 22, 233-240 (1999).
    • (1999) Diabetes Care , vol.22 , pp. 233-240
    • Coutinho, M.1    Gerstein, H.C.2    Wang, Y.3    Yusuf, S.4
  • 5
    • 45149131667 scopus 로고    scopus 로고
    • Effects of intensive glucose lowering in type 2 diabetes
    • Action to Control Cardiovascular Risk in Diabetes Study Group et al. Effects of intensive glucose lowering in type 2 diabetes. N. Engl. J. Med. 358, 2545-2559 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2545-2559
  • 6
    • 58149389215 scopus 로고    scopus 로고
    • Glucose control and vascular complications in veterans with type 2 diabetes
    • Duckworth, W. et al. Glucose control and vascular complications in veterans with type 2 diabetes. N. Engl. J. Med. 360, 129-139 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 129-139
    • Duckworth, W.1
  • 7
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • ADVANCE Collaborative Group et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N. Engl. J. Med. 358, 2560-2572 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2560-2572
  • 8
    • 84864270406 scopus 로고    scopus 로고
    • Basal insulin and cardiovascular and other outcomes in dysglycemia
    • The ORIGIN Trial Investigators. Basal insulin and cardiovascular and other outcomes in dysglycemia. N. Engl. J. Med. 367, 319-328 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 319-328
  • 9
    • 65649106228 scopus 로고    scopus 로고
    • Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: A meta-analysis of randomised controlled trials
    • Ray, K. K. et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: A meta-analysis of randomised controlled trials. Lancet 373, 1765-1772 (2009).
    • (2009) Lancet , vol.373 , pp. 1765-1772
    • Ray, K.K.1
  • 10
    • 84919428088 scopus 로고    scopus 로고
    • Effects of intensive glycaemic control on ischaemic heart disease: Analysis of data from the randomised, controlled ACCORD trial
    • Gerstein, H. C. et al. Effects of intensive glycaemic control on ischaemic heart disease: Analysis of data from the randomised, controlled ACCORD trial. Lancet 384, 1936-1941 (2014).
    • (2014) Lancet , vol.384 , pp. 1936-1941
    • Gerstein, H.C.1
  • 11
    • 84878465124 scopus 로고    scopus 로고
    • The Canadian Diabetes Association 2013 clinical practice guidelines-raising the bar and setting higher standards!
    • Cheng, A. Y. & Lau, D. C. The Canadian Diabetes Association 2013 clinical practice guidelines-raising the bar and setting higher standards! Can. J. Diabetes 37, 137-138 (2013).
    • (2013) Can. J. Diabetes , vol.37 , pp. 137-138
    • Cheng, A.Y.1    Lau, D.C.2
  • 12
    • 84876782437 scopus 로고    scopus 로고
    • Executive summary: Standards of medical care in diabetes-2013
    • American Diabetes Association. Executive summary: Standards of medical care in diabetes-2013. Diabetes Care 36 (Suppl 1), S4-10 (2013).
    • (2013) Diabetes Care , vol.36 , pp. 4-10
  • 13
    • 58849139160 scopus 로고    scopus 로고
    • The ACCORD Trial and control of blood glucose level in type 2 diabetes mellitus: Time to challenge conventional wisdom
    • Havas, S. The ACCORD Trial and control of blood glucose level in type 2 diabetes mellitus: Time to challenge conventional wisdom. Arch. Intern. Med. 169, 150-154 (2009).
    • (2009) Arch. Intern. Med. , vol.169 , pp. 150-154
    • Havas, S.1
  • 14
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw, J. E., Sicree, R. A. & Zimmet, P. Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 87, 4-14 (2010).
    • (2010) Diabetes Res. Clin. Pract. , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 16
    • 43449108812 scopus 로고    scopus 로고
    • Economic costs of diabetes in the U.S. In 2007
    • American Diabetes Association. Economic costs of diabetes in the U.S. In 2007. Diabetes Care 31, 596-615 (2008).
    • (2008) Diabetes Care , vol.31 , pp. 596-615
  • 17
    • 34548356858 scopus 로고    scopus 로고
    • The impact of residual and unmeasured confounding in epidemiologic studies: A simulation study
    • Fewell, Z., Davey Smith, G. & Sterne, J. A. C. The impact of residual and unmeasured confounding in epidemiologic studies: A simulation study. Am. J. Epidemiol. 166, 646-655 (2007).
    • (2007) Am. J. Epidemiol. , vol.166 , pp. 646-655
    • Fewell, Z.1    Davey Smith, G.2    Sterne, J.A.C.3
  • 18
    • 84899490570 scopus 로고    scopus 로고
    • Insulin resistance and hyperglycaemia in cardiovascular disease development
    • Laakso, M. & Kuusisto, J. Insulin resistance and hyperglycaemia in cardiovascular disease development. Nat. Rev. Endocrinol. 10, 293-302 (2014).
    • (2014) Nat. Rev. Endocrinol. , vol.10 , pp. 293-302
    • Laakso, M.1    Kuusisto, J.2
  • 19
    • 84892649479 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2014
    • American Diabetes Association. Standards of medical care in diabetes-2014. Diabetes Care 37 (Suppl 1), S14-S80 (2014).
    • (2014) Diabetes Care , vol.37 , pp. 14-80
  • 20
    • 84857627603 scopus 로고    scopus 로고
    • Mendelian randomization: Application to cardiovascular disease
    • Timpson, N. J., Wade, K. H. & Smith, G. D. Mendelian randomization: Application to cardiovascular disease. Curr. Hypertens. Rep. 14, 29-37 (2012).
    • (2012) Curr. Hypertens. Rep. , vol.14 , pp. 29-37
    • Timpson, N.J.1    Wade, K.H.2    Smith, G.D.3
  • 21
    • 84861827079 scopus 로고    scopus 로고
    • Using multiple genetic variants as instrumental variables for modifiable risk factors
    • Palmer, T. M. et al. Using multiple genetic variants as instrumental variables for modifiable risk factors. Stat. Methods Med. Res. 21, 223-242 (2012).
    • (2012) Stat. Methods Med. Res. , vol.21 , pp. 223-242
    • Palmer, T.M.1
  • 22
    • 84885840876 scopus 로고    scopus 로고
    • Mendelian randomization analysis with multiple genetic variants using summarized data
    • Burgess, S., Butterworth, A. & Thompson, S. G. Mendelian randomization analysis with multiple genetic variants using summarized data. Genet. Epidemiol. 37, 658-665 (2013).
    • (2013) Genet. Epidemiol. , vol.37 , pp. 658-665
    • Burgess, S.1    Butterworth, A.2    Thompson, S.G.3
  • 23
    • 84884736257 scopus 로고    scopus 로고
    • Use of allele scores as instrumental variables for Mendelian randomization
    • Burgess, S. & Thompson, S. G. Use of allele scores as instrumental variables for Mendelian randomization. Int. J. Epidemiol. 42, 1134-1144 (2013).
    • (2013) Int. J. Epidemiol. , vol.42 , pp. 1134-1144
    • Burgess, S.1    Thompson, S.G.2
  • 24
    • 84865693929 scopus 로고    scopus 로고
    • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
    • Scott, R. A. et al. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat. Genet. 44, 991-1005 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 991-1005
    • Scott, R.A.1
  • 25
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris, A. P. et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 44, 981-990 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 981-990
    • Morris, A.P.1
  • 26
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • Voight, B. F. et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet. 42, 579-589 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 579-589
    • Voight, B.F.1
  • 27
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • CARDIoGRAMplusC4D Consortium et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat. Genet. 45, 25-33 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 25-33
  • 28
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Schunkert, H. et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat. Genet. 43, 333-338 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 333-338
    • Schunkert, H.1
  • 29
    • 80052325959 scopus 로고    scopus 로고
    • Pervasive sharing of genetic effects in autoimmune disease
    • Cotsapas, C. et al. Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet. 7, e1002254 (2011).
    • (2011) PLoS Genet. , vol.7 , pp. e1002254
    • Cotsapas, C.1
  • 30
    • 57249114505 scopus 로고    scopus 로고
    • SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
    • Johnson, A. D. et al. SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 24, 2938-2939 (2008).
    • (2008) Bioinformatics , vol.24 , pp. 2938-2939
    • Johnson, A.D.1
  • 31
    • 53349173117 scopus 로고    scopus 로고
    • Sensitivity of between-study heterogeneity in meta-analysis: Proposed metrics and empirical evaluation
    • Patsopoulos, N. A., Evangelou, E. & Ioannidis, J. P. Sensitivity of between-study heterogeneity in meta-analysis: Proposed metrics and empirical evaluation. Int. J. Epidemiol. 37, 1148-1157 (2008).
    • (2008) Int. J. Epidemiol. , vol.37 , pp. 1148-1157
    • Patsopoulos, N.A.1    Evangelou, E.2    Ioannidis, J.P.3
  • 32
    • 84901298851 scopus 로고    scopus 로고
    • Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity
    • Dimas, A. S. et al. Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. Diabetes 63, 2158-2171 (2014).
    • (2014) Diabetes , vol.63 , pp. 2158-2171
    • Dimas, A.S.1
  • 33
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
    • Lawlor, D. A., Harbord, R. M., Sterne, J. A. C., Timpson, N. & Davey Smith, G. Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology. Stat. Med. 27, 1133-1163 (2008).
    • (2008) Stat. Med. , vol.27 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.C.3    Timpson, N.4    Davey Smith, G.5
  • 34
    • 0037322022 scopus 로고    scopus 로고
    • Mendelian randomization: Can genetic epidemiology contribute to understanding environmental determinants of disease? Int
    • Smith, G. D. & Ebrahim, S. 'Mendelian randomization': Can genetic epidemiology contribute to understanding environmental determinants of disease? Int. J. Epidemiol. 32, 1-22 (2003).
    • (2003) J. Epidemiol. , vol.32 , pp. 1-22
    • Smith, G.D.1    Ebrahim, S.2
  • 36
    • 84862205208 scopus 로고    scopus 로고
    • Nonfasting glucose, ischemic heart disease, and myocardial infarction
    • Benn, M. et al. Nonfasting glucose, ischemic heart disease, and myocardial infarction. J. Am. Coll. Cardiol. 59, 2356-2365 (2012).
    • (2012) J. Am. Coll. Cardiol. , vol.59 , pp. 2356-2365
    • Benn, M.1
  • 37
    • 84899479198 scopus 로고    scopus 로고
    • Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study
    • Adams, J. N. et al. Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study. Cardiovasc. Diabetol. 13, 77 (2014).
    • (2014) Cardiovasc. Diabetol. , vol.13 , pp. 77
    • Adams, J.N.1
  • 38
    • 84905658469 scopus 로고    scopus 로고
    • Mendelian randomization studies in coronary artery disease
    • Jansen, H., Samani, N. J. & Schunkert, H. Mendelian randomization studies in coronary artery disease. Eur. Heart J. 35, 1917-1924 (2014).
    • (2014) Eur. Heart J. , vol.35 , pp. 1917-1924
    • Jansen, H.1    Samani, N.J.2    Schunkert, H.3
  • 39
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study
    • Voight, B. F. et al. Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study. Lancet 380, 572-580 (2012).
    • (2012) Lancet , vol.380 , pp. 572-580
    • Voight, B.F.1
  • 40
    • 55249087635 scopus 로고    scopus 로고
    • Genetically elevated C-reactive protein and ischemic vascular disease
    • Zacho, J. et al. Genetically elevated C-reactive protein and ischemic vascular disease. N. Engl. J. Med. 359, 1897-1908 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 1897-1908
    • Zacho, J.1
  • 41
    • 84883163053 scopus 로고    scopus 로고
    • Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease
    • Van Meurs, J. B. et al. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am. J. Clin. Nutr. 98, 668-676 (2013).
    • (2013) Am. J. Clin. Nutr. , vol.98 , pp. 668-676
    • Van Meurs, J.B.1
  • 42
    • 84871771750 scopus 로고    scopus 로고
    • Genetically elevated bilirubin and risk of ischaemic heart disease: Three Mendelian randomization studies and a meta-analysis
    • Stender, S., Frikke-Schmidt, R., Nordestgaard, B. G., Grande, P. & Tybjaerg-Hansen, A. Genetically elevated bilirubin and risk of ischaemic heart disease: Three Mendelian randomization studies and a meta-analysis. J. Intern. Med. 273, 59-68 (2013).
    • (2013) J. Intern. Med. , vol.273 , pp. 59-68
    • Stender, S.1    Frikke-Schmidt, R.2    Nordestgaard, B.G.3    Grande, P.4    Tybjaerg-Hansen, A.5
  • 43
    • 84881442965 scopus 로고    scopus 로고
    • Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts
    • Palmer, T. M. et al. Association of plasma uric acid with ischaemic heart disease and blood pressure: Mendelian randomisation analysis of two large cohorts. Br. Med. J. 347, f4262-f4262 (2013).
    • (2013) Br. Med. J. , vol.347 , pp. 4262-4262
    • Palmer, T.M.1
  • 44
    • 84876677420 scopus 로고    scopus 로고
    • Genetic predisposition to higher blood pressure increases coronary artery disease risk
    • Lieb, W. et al. Genetic predisposition to higher blood pressure increases coronary artery disease risk. Hypertension 61, 995-1001 (2013).
    • (2013) Hypertension , vol.61 , pp. 995-1001
    • Lieb, W.1
  • 45
    • 52349083201 scopus 로고    scopus 로고
    • Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease-A Mendelian randomisation study
    • Linsel-Nitschke, P. et al. Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease-A Mendelian randomisation study. PLoS ONE 3, e2986 (2008).
    • (2008) PLoS ONE , vol.3 , pp. e2986
    • Linsel-Nitschke, P.1
  • 46
    • 78650052979 scopus 로고    scopus 로고
    • Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease
    • Haase, C. L., Tybjaerg-Hansen, A., Grande, P. & Frikke-Schmidt, R. Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease. J. Clin. Endocrinol. Metab. 95, E500-E510 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 500-510
    • Haase, C.L.1    Tybjaerg-Hansen, A.2    Grande, P.3    Frikke-Schmidt, R.4
  • 47
    • 84887058576 scopus 로고    scopus 로고
    • Common variants associated with plasma triglycerides and risk for coronary artery disease
    • Do, R. et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat. Genet. 45, 1345-1352 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 1345-1352
    • Do, R.1
  • 48
    • 84876175810 scopus 로고    scopus 로고
    • Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
    • Jørgensen, A. B. et al. Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. Eur. Heart J. 34, 1826-1833 (2013).
    • (2013) Eur. Heart J. , vol.34 , pp. 1826-1833
    • Jørgensen, A.B.1
  • 49
    • 84879326263 scopus 로고    scopus 로고
    • The role of adiposity in cardiometabolic traits: A Mendelian randomization analysis
    • Fall, T. et al. The role of adiposity in cardiometabolic traits: A Mendelian randomization analysis. PLoS Med. 10, e1001474 (2013).
    • (2013) PLoS Med. , vol.10 , pp. e1001474
    • Fall, T.1
  • 50
    • 84879415419 scopus 로고    scopus 로고
    • The shared allelic architecture of adiponectin levels and coronary artery disease
    • Dastani, Z. et al. The shared allelic architecture of adiponectin levels and coronary artery disease. Atherosclerosis 229, 145-148 (2013).
    • (2013) Atherosclerosis , vol.229 , pp. 145-148
    • Dastani, Z.1
  • 51
    • 84891540644 scopus 로고    scopus 로고
    • Mendelian randomisation studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes
    • Yaghootkar, H. et al. Mendelian randomisation studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes 62, 3589-3598 (2013).
    • (2013) Diabetes , vol.62 , pp. 3589-3598
    • Yaghootkar, H.1
  • 52
    • 84885819536 scopus 로고    scopus 로고
    • Predicting risk of type 2 diabetes mellitus with genetic risk models on the basis of established genome-wide association markers: A systematic review
    • Bao, W. et al. Predicting risk of type 2 diabetes mellitus with genetic risk models on the basis of established genome-wide association markers: A systematic review. Am. J. Epidemiol. 178, 1197-1207 (2013).
    • (2013) Am. J. Epidemiol. , vol.178 , pp. 1197-1207
    • Bao, W.1
  • 53
    • 84901380958 scopus 로고    scopus 로고
    • Polygenic type 2 diabetes prediction at the limit of common variant detection
    • Vassy, J. L. et al. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes 63, 2172-2182 (2014).
    • (2014) Diabetes , vol.63 , pp. 2172-2182
    • Vassy, J.L.1
  • 54
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1
  • 55
    • 80053907554 scopus 로고    scopus 로고
    • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
    • Ehret, G. B. et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature 478, 103-109 (2011).
    • (2011) Nature , vol.478 , pp. 103-109
    • Ehret, G.B.1
  • 56
    • 84879677633 scopus 로고    scopus 로고
    • Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
    • Randall, J. C. et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 9, e1003500 (2013).
    • (2013) PLoS Genet. , vol.9 , pp. e1003500
    • Randall, J.C.1
  • 58
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins, J. P. & Thompson, S. G. Quantifying heterogeneity in a meta-analysis. Stat. Med. 21, 1539-1558 (2002).
    • (2002) Stat. Med. , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2


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