Comparative proteomic analysis of the molecular responses of mouse macrophages to titanium dioxide and copper oxide nanoparticles unravels some toxic mechanisms for copper oxide nanoparticles in macrophages

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Triboulet, Sarah ^a   Aude Garcia, Catherine ^b,c   Armand, Lucie ^a   Collin Faure, Véronique ^b   Chevallet, Mireille ^b   Diemer, Hélène ^d   Gerdil, Adèle ^e   Proamer, Fabienne ^f   Strub, Jean Marc ^d   Habert, Aurélie ^e   Herlin, Nathalie ^e   Van Dorsselaer, Alain ^d   Carrière, Marie ^a   Rabilloud, Thierry ^c  

^a UNIV GRENOBLE ALPES   (France)

^b CEA GRENOBLE   (France)

^c CNRS UMR5249   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e CEA SACLAY   (France)

^f INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALDEHYDE REDUCTASE; COPPER ION; COPPER OXIDE; CYCLINE; ELONGATION FACTOR; FERRITIN; GALACTOKINASE; GLUTAMATE CYSTEINE LIGASE; GUANINE NUCLEOTIDE BINDING PROTEIN GAMMA SUBUNIT; HEME OXYGENASE; HEME OXYGENASE 1; INTERLEUKIN 6; NANOPARTICLE; PEROXIREDOXIN 6; SEPIAPTERIN REDUCTASE; STATHMIN; TETRAHYDROBIOPTERIN; TITANIUM DIOXIDE; TROPOMODULIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR PROTEIN; UBIQUITIN THIOLESTERASE; COPPER; CUPROUS OXIDE; CYTOKINE; DOPA; GLUTATHIONE; METAL NANOPARTICLE; NITRIC OXIDE; TITANIUM;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; COMET ASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOSKELETON; DISSOLUTION; DNA STRAND; DNA STRAND BREAKAGE; ENDOCYTOSIS; GLUTATHIONE METABOLISM; IMAGE ANALYSIS; MACROPHAGE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; SUPERNATANT; TRANSMISSION ELECTRON MICROSCOPY; TWO DIMENSIONAL GEL ELECTROPHORESIS; X RAY DIFFRACTION; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; COMPARATIVE STUDY; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; ENZYME INDUCTION; METABOLISM; PROCEDURES;

ANIMALS; CELL SURVIVAL; COPPER; CYTOKINES; DIHYDROXYPHENYLALANINE; DNA BREAKS, DOUBLE-STRANDED; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INDUCTION; GLUTATHIONE; HEME OXYGENASE (DECYCLIZING); MACROPHAGES; METAL NANOPARTICLES; MICE; NITRIC OXIDE; PHAGOCYTOSIS; PROTEOMICS; TITANIUM;

EID: 84930658038     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124496     Document Type: Article

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