DNA double-strand breaks by asbestos, silica, and titanium dioxide: Possible biomarker of carcinogenic potential?

American Journal of Respiratory Cell and Molecular Biology

Volumn 43, Issue 2, 2010, Pages 210-219

  Msiska, Zola ^b   Pacurari, Maricica ^a   Mishra, Anurag ^a   Leonard, Stephen S ^a   Castranova, Vince ^a   Vallyathan, Val ^b  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b NONE

Author keywords

Asbestos; Carcinogenesis; DNA damage; H2AX; Silica

Indexed keywords

ASBESTOS; BIOLOGICAL MARKER; CASPASE 3; CASPASE 7; CROCIDOLITE; DOUBLE STRANDED DNA; HISTONE H2AX; LACTATE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; TITANIUM DIOXIDE; CARCINOGEN; CASPASE; DNA; TITANIUM; TUMOR MARKER;

AIRWAY; APOPTOSIS; ARTICLE; CANCER CELL; CARCINOGENIC ACTIVITY; CARCINOGENICITY; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; LUNG ALVEOLUS CELL; LUNG CANCER; PARTICLE SIZE; RESPIRATORY EPITHELIUM; SCANNING ELECTRON MICROSCOPY; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; ELECTRON SPIN RESONANCE; METABOLISM; NEOPLASM; TUMOR CELL LINE;

ANIMALIA;

ASBESTOS; CARCINOGENS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; DNA; DNA BREAKS, DOUBLE-STRANDED; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME ACTIVATION; HUMANS; NEOPLASMS; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; TITANIUM; TUMOR MARKERS, BIOLOGICAL;

EID: 77955495793     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0062OC     Document Type: Article

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