Cationic lipophosphoramidates containing a hydroxylated polar headgroup for improving gene delivery

Molecular Pharmaceutics

Volumn 12, Issue 6, 2015, Pages 1902-1910

  Berchel, Mathieu ^a,e   Le Gall, Tony ^b,e   Haelters, Jean Pierre ^a   Lehn, Pierre ^b   Montier, Tristan ^b,c,d,e   Jaffrès, Paul Alain ^a,e  

^a UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^b INSERM   (France)

^c BREST UNIVERSITY HOSPITAL   (France)

^d FACULTÉ DE MÉDECINE ET DES SCIENCES DE LA SANTÉ   (France)

^e UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

Author keywords

amphiphiles; cationic lipids; DNA; gene delivery; liposomes

Indexed keywords

AMPHOPHILE; ARSENOLIPOPHOSPHORAMIDATE; FUNCTIONAL GROUP; HYDROXYETHYLDIMETHYLAMMONIUM; HYDROXYL GROUP; LIPOPLEX; LIPOSOME; PHOSPHORAMIDIC ACID DERIVATIVE; PLASMID DNA; TRIMETHYLAMMONIUM SALT DERIVATIVE; UNCLASSIFIED DRUG; CATION; DRUG CARRIER; LIPID; PHENYLTRIMETHYLAMMONIUM; QUATERNARY AMMONIUM DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG FORMULATION; DRUG SYNTHESIS; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARTICLE SIZE; PLASMID; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; ZETA POTENTIAL; CHEMISTRY; GENE TRANSFER; HYDROXYLATION;

CATIONS; DRUG CARRIERS; GENE TRANSFER TECHNIQUES; HYDROXYLATION; LIPIDS; LIPOSOMES; QUATERNARY AMMONIUM COMPOUNDS;

EID: 84930655632     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500807k     Document Type: Article

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