PH-Responsive poly(D,L-lactic-co-glycolic acid) nanoparticles with rapid antigen release behavior promote immune response

ACS Nano

Volumn 9, Issue 5, 2015, Pages 4925-4938

  Liu, Qi ^a,b   Chen, Xiaoming ^a,b   Jia, Jilei ^a,b   Zhang, Weifeng ^a,b   Yang, Tingyuan ^a   Wang, Lianyan ^a   Ma, Guanghui ^a,c  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Collaborative Innovation Center of Chemical Science and Engineering   (China)

Author keywords

antigen intracellular rapid release; dendritic cells; pH responsive; PLGA nanoparticles; vaccine delivery and adjuvant system

Indexed keywords

AMMONIUM BICARBONATE; ANTIBODIES; ANTIGENS; CELLS; COPOLYMERS; CYTOLOGY; DISEASE CONTROL; ENZYME ACTIVITY; MOBILE SECURITY; NANOPARTICLES; T-CELLS; VACCINES; VIRUSES;

DENDRITIC CELLS; PH-RESPONSIVE; PLGA NANOPARTICLES; RAPID RELEASE; VACCINE DELIVERY;

IMMUNE SYSTEM;

ANTIGEN; DRUG CARRIER; IMMUNOLOGICAL ADJUVANT; LACTIC ACID; NANOPARTICLE; OVALBUMIN; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; VACCINE;

ANIMAL; ANTIGEN PRESENTATION; CELLULAR IMMUNITY; CHEMISTRY; CYTOLOGY; DENDRITIC CELL; DRUG RELEASE; IMMUNOLOGY; INTRACELLULAR SPACE; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PH; T LYMPHOCYTE; TIME FACTOR;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; DENDRITIC CELLS; DRUG CARRIERS; DRUG LIBERATION; HYDROGEN-ION CONCENTRATION; IMMUNITY, CELLULAR; INTRACELLULAR SPACE; LACTIC ACID; LYMPHOCYTE ACTIVATION; MICE; NANOPARTICLES; OVALBUMIN; POLYGLYCOLIC ACID; T-LYMPHOCYTES; TIME FACTORS; VACCINES;

EID: 84930636958     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn5066793     Document Type: Article

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