Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

Molecular Phylogenetics and Evolution

Volumn 91, Issue , 2015, Pages 27-40

  Krishnan, Arunkumar ^a   Mustafa, Arshi ^a,b   Almén, Markus Sällman ^a   Fredriksson, Robert ^a   Williams, Michael J ^a   Schiöth, Helgi B ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

G protein; Gene gain losses; GPCRs; Holozoans; Signal transduction

Indexed keywords

ARTHROPODA; BILATERIA; DROSOPHILA MELANOGASTER; INVERTEBRATA; METAZOA; VERTEBRATA;

HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL; CLASSIFICATION; GENETICS; INVERTEBRATE; MOLECULAR EVOLUTION; MULTIGENE FAMILY; PHYLOGENY; VERTEBRATE;

ANIMALS; EVOLUTION, MOLECULAR; HETEROTRIMERIC GTP-BINDING PROTEINS; INVERTEBRATES; MULTIGENE FAMILY; PHYLOGENY; VERTEBRATES;

EID: 84930635982     PISSN: 10557903     EISSN: 10959513     Source Type: Journal    
DOI: 10.1016/j.ympev.2015.05.009     Document Type: Article

References (49)

1. Anantharaman V., Abhiman S., de Souza R.F., Aravind L. Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system. Gene 2011, 475:63-78.
2. Bastiani C., Mendel J. Heterotrimeric G proteins in C. elegans. WormBook 2006, 1-25.
3. Bradford W., Buckholz A., Morton J., Price C., Jones A.M., Urano D. Eukaryotic G protein signaling evolved to require G protein-coupled receptors for activation. Sci. Signal. 2013, 6:ra37.
4. Cabrera-Vera T.M., Vanhauwe J., Thomas T.O., Medkova M., Preininger A., Mazzoni M.R., Hamm H.E. Insights into G protein structure, function, and regulation. Endocr. Rev. 2003, 24:765-781.
5. Caruso V., Lagerstrom M.C., Olszewski P.K., Fredriksson R., Schioth H.B. Synaptic changes induced by melanocortin signalling. Nat. Rev. Neurosci. 2014, 15:98-110.
6. Civelli O., Reinscheid R.K., Zhang Y., Wang Z., Fredriksson R., Schioth H.B. G protein-coupled receptor deorphanizations. Annu. Rev. Pharmacol. Toxicol. 2013, 53:127-146.
7. de Mendoza A., Sebe-Pedros A., Ruiz-Trillo I. The evolution of the GPCR signaling system in eukaryotes: modularity, conservation, and the transition to metazoan multicellularity. Genome Biol. Evol. 2014, 6:606-619.
8. Dolph P.J., Man-Son-Hing H., Yarfitz S., Colley N.J., Deer J.R., Spencer M., Hurley J.B., Zuker C.S. An eye-specific G beta subunit essential for termination of the phototransduction cascade. Nature 1994, 370:59-61.
9. Downes G.B., Gautam N. The G protein subunit gene families. Genomics 1999, 62:544-552.
10. Dupre D.J., Robitaille M., Rebois R.V., Hebert T.E. The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes. Annu. Rev. Pharmacol. Toxicol. 2009, 49:31-56.
11. Gautam N., Downes G.B., Yan K., Kisselev O. The G-protein betagamma complex. Cell Signal. 1998, 10:447-455.
12. Hunter S., Jones P., Mitchell A., Apweiler R., Attwood T.K., Bateman A., Bernard T., Binns D., Bork P., Burge S., de Castro E., Coggill P., Corbett M., Das U., Daugherty L., Duquenne L., Finn R.D., Fraser M., Gough J., Haft D., Hulo N., Kahn D., Kelly E., Letunic I., Lonsdale D., Lopez R., Madera M., Maslen J., McAnulla C., McDowall J., McMenamin C., Mi H., Mutowo-Muellenet P., Mulder N., Natale D., Orengo C., Pesseat S., Punta M., Quinn A.F., Rivoire C., Sangrador-Vegas A., Selengut J.D., Sigrist C.J., Scheremetjew M., Tate J., Thimmajanarthanan M., Thomas P.D., Wu C.H., Yeats C., Yong S.Y. InterPro in 2011: new developments in the family and domain prediction database. Nucl. Acids Res. 2012, 40:D306-312.
13. Hurowitz E.H., Melnyk J.M., Chen Y.J., Kouros-Mehr H., Simon M.I., Shizuya H. Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes. DNA Res. 2000, 7:111-120.
14. Jansen G., Thijssen K.L., Werner P., van der Horst M., Hazendonk E., Plasterk R.H. The complete family of genes encoding G proteins of Caenorhabditis elegans. Nat. Genet. 1999, 21:414-419.
15. Johnston C.A., Siderovski D.P. Receptor-mediated activation of heterotrimeric G-proteins: current structural insights. Mol. Pharmacol. 2007, 72:219-230.
16. Katoh K., Standley D.M. MAFFT multiple sequence alignment software version 7: improvements in performance and usability. Mol. Biol. Evol. 2013, 30:772-780.
17. Katritch V., Cherezov V., Stevens R.C. Structure-function of the G protein-coupled receptor superfamily. Annu. Rev. Pharmacol. Toxicol. 2013, 53:531-556.
18. Khan S.M., Sleno R., Gora S., Zylbergold P., Laverdure J.P., Labbe J.C., Miller G.J., Hebert T.E. The expanding roles of Gbetagamma subunits in G protein-coupled receptor signaling and drug action. Pharmacol. Rev. 2013, 65:545-577.
19. Krishnan A., Almen M.S., Fredriksson R., Schioth H.B. The origin of GPCRs: identification of mammalian like rhodopsin, adhesion, glutamate and frizzled GPCRs in fungi. PLoS ONE 2012, 7:e29817.
20. Lagerstrom M.C., Schioth H.B. Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat. Rev. Drug Discov. 2008, 7:339-357.
21. Lagman D., Sundstrom G., Ocampo Daza D., Abalo X.M., Larhammar D. Expansion of transducin subunit gene families in early vertebrate tetraploidizations. Genomics 2012, 100:203-211.
22. Lamb T.D. Evolution of vertebrate retinal photoreception. Philos. Trans. Roy. Soc. Lond. B Biol. Sci. 2009, 364:2911-2924.
23. Lans H., Rademakers S., Jansen G. A network of stimulatory and inhibitory Galpha-subunits regulates olfaction in Caenorhabditis elegans. Genetics 2004, 167:1677-1687.
24. Larhammar D., Nordstrom K., Larsson T.A. Evolution of vertebrate rod and cone phototransduction genes. Philos. Trans. Roy. Soc. Lond. B Biol. Sci. 2009, 364:2867-2880.
25. Lin Y.G., Weadick C.J., Santini F., Chang B.S. Molecular evolutionary analysis of vertebrate transducins: a role for amino acid variation in photoreceptor deactivation. J. Mol. Evol. 2013, 77:231-245.
26. Malbon C.C. G proteins in development. Nat. Rev. Mol. Cell Biol. 2005, 6:689-701.
27. Marchler-Bauer A., Lu S., Anderson J.B., Chitsaz F., Derbyshire M.K., DeWeese-Scott C., Fong J.H., Geer L.Y., Geer R.C., Gonzales N.R., Gwadz M., Hurwitz D.I., Jackson J.D., Ke Z., Lanczycki C.J., Lu F., Marchler G.H., Mullokandov M., Omelchenko M.V., Robertson C.L., Song J.S., Thanki N., Yamashita R.A., Zhang D., Zhang N., Zheng C., Bryant S.H. CDD: a conserved domain database for the functional annotation of proteins. Nucl. Acids Res. 2011, 39:D225-229.
28. Melien O. Heterotrimeric G proteins and disease. Meth. Mol. Biol. 2007, 361:119-144.
29. Nordstrom K.J., Sallman Almen M., Edstam M.M., Fredriksson R., Schioth H.B. Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families. Mol. Biol. Evol. 2011, 28:2471-2480.
30. O'Halloran D.M., Fitzpatrick D.A., McCormack G.P., McInerney J.O., Burnell A.M. The molecular phylogeny of a nematode-specific clade of heterotrimeric G-protein alpha-subunit genes. J. Mol. Evol. 2006, 63:87-94.
31. Oka Y., Saraiva L.R., Kwan Y.Y., Korsching S.I. The fifth class of Galpha proteins. Proc. Natl. Acad. Sci. USA 2009, 106:1484-1489.
32. Oldham W.M., Hamm H.E. Structural basis of function in heterotrimeric G proteins. Quart. Rev. Biophys. 2006, 39:117-166.
33. Oldham W.M., Hamm H.E. Heterotrimeric G protein activation by G-protein-coupled receptors. Nat. Rev. Mol. Cell Biol. 2008, 9:60-71.
34. Punta M., Coggill P.C., Eberhardt R.Y., Mistry J., Tate J., Boursnell C., Pang N., Forslund K., Ceric G., Clements J., Heger A., Holm L., Sonnhammer E.L., Eddy S.R., Bateman A., Finn R.D. The Pfam protein families database. Nucl. Acids Res. 2012, 40:D290-301.
35. Ronquist F., Teslenko M., van der Mark P., Ayres D.L., Darling A., Hohna S., Larget B., Liu L., Suchard M.A., Huelsenbeck J.P. MrBayes 3.2: efficient Bayesian phylogenetic inference and model choice across a large model space. Syst. Biol. 2012, 61:539-542.
36. Rosenbaum D.M., Rasmussen S.G., Kobilka B.K. The structure and function of G-protein-coupled receptors. Nature 2009, 459:356-363.
37. Seack J., Kruse M., Muller W.E. Evolutionary analysis of G-proteins in early metazoans: cloning of alpha- and beta-subunits from the sponge Geodia cydonium. Biochim. Biophys. Acta 1998, 1401:93-103.
38. Smrcka A.V. G protein betagamma subunits: central mediators of G protein-coupled receptor signaling. Cell. Mol. Life Sci. 2008, 65:2191-2214.
39. Spiegel A.M., Weinstein L.S. Inherited diseases involving g proteins and g protein-coupled receptors. Annu. Rev. Med. 2004, 55:27-39.
40. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 2011, 28:2731-2739.
41. Tesmer J.J. The quest to understand heterotrimeric G protein signaling. Nat. Struct. Mol. Biol. 2010, 17:650-652.
42. Venkatakrishnan A.J., Deupi X., Lebon G., Tate C.G., Schertler G.F., Babu M.M. Molecular signatures of G-protein-coupled receptors. Nature 2013, 494:185-194.
43. Waterhouse A.M., Procter J.B., Martin D.M., Clamp M., Barton G.J. Jalview Version 2 - a multiple sequence alignment editor and analysis workbench. Bioinformatics 2009, 25:1189-1191.
44. Watson A.J., Katz A., Simon M.I. A fifth member of the mammalian G-protein beta-subunit family. Expression in brain and activation of the beta 2 isotype of phospholipase C. J. Biol. Chem. 1994, 269:22150-22156.
45. Weinstein L.S., Chen M., Xie T., Liu J. Genetic diseases associated with heterotrimeric G proteins. Trends Pharmacol. Sci. 2006, 27:260-266.
46. Wettschureck N., Offermanns S. Mammalian G proteins and their cell type specific functions. Physiol. Rev. 2005, 85:1159-1204.
47. Wilkie T.M., Gilbert D.J., Olsen A.S., Chen X.N., Amatruda T.T., Korenberg J.R., Trask B.J., de Jong P., Reed R.R., Simon M.I., et al. Evolution of the mammalian G protein alpha subunit multigene family. Nat. Genet. 1992, 1:85-91.
48. Yang W., Hildebrandt J.D. Genomic analysis of G protein gamma subunits in human and mouse - the relationship between conserved gene structure and G protein betagamma dimer formation. Cell Signal. 2006, 18:194-201.
49. Yarfitz S.L., Running Deer J.L., Froelick G., Colley N.J., Hurley J.B. In situ assay of light-stimulated G protein activity in Drosophila photoreceptor G protein beta mutants. J. Biol. Chem. 1994, 269:30340-30344.