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Volumn 291, Issue , 2015, Pages 130-139

The contribution of hypothalamic neuroendocrine, neuroplastic and neuroinflammatory processes to lipopolysaccharide-induced depressive-like behaviour in female and male rats: Involvement of glucocorticoid receptor and C/EBP-β

Author keywords

C EBP ; Depressive like behaviour; Glucocorticoid receptor; Hypothalamus; Lypopolysaccharide (LPS); Sex

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CCAAT ENHANCER BINDING PROTEIN BETA; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; CYCLOOXYGENASE 2; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; CEBPB PROTEIN, RAT; PTGS2 PROTEIN, RAT;

EID: 84930626972     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2015.05.029     Document Type: Article
Times cited : (68)

References (60)
  • 1
    • 0034863624 scopus 로고    scopus 로고
    • Psychological stress and the inflammatory response system
    • Maes M. Psychological stress and the inflammatory response system. Clin. Sci. (Lond.) 2001, 101:193-194.
    • (2001) Clin. Sci. (Lond.) , vol.101 , pp. 193-194
    • Maes, M.1
  • 3
    • 0032498325 scopus 로고    scopus 로고
    • Depression, stress and immunological activation: the role of cytokines in depressive disorders
    • Connor T.J., Leonard B.E. Depression, stress and immunological activation: the role of cytokines in depressive disorders. Life Sci. 1998, 62:583-606.
    • (1998) Life Sci. , vol.62 , pp. 583-606
    • Connor, T.J.1    Leonard, B.E.2
  • 4
    • 0033120020 scopus 로고    scopus 로고
    • Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events
    • Maes M., Lin A.H., Delmeire L., Van Gastel A., Kenis G., De Jongh R., Bosmans E. Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events. Biol. Psychiatry 1999, 45:833-839.
    • (1999) Biol. Psychiatry , vol.45 , pp. 833-839
    • Maes, M.1    Lin, A.H.2    Delmeire, L.3    Van Gastel, A.4    Kenis, G.5    De Jongh, R.6    Bosmans, E.7
  • 5
    • 0034964247 scopus 로고    scopus 로고
    • Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis
    • Mikova O., Yakimova R., Bosmans E., Kenis G., Maes M. Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. Eur. Neuropsychopharmacol. 2001, 11:203-208.
    • (2001) Eur. Neuropsychopharmacol. , vol.11 , pp. 203-208
    • Mikova, O.1    Yakimova, R.2    Bosmans, E.3    Kenis, G.4    Maes, M.5
  • 6
    • 0036904039 scopus 로고    scopus 로고
    • Cytokine-induced changes in mood and behaviour: implications for 'depression due to a general medical condition', immunotherapy and antidepressive treatment
    • Pollak Y., Yirmiya R. Cytokine-induced changes in mood and behaviour: implications for 'depression due to a general medical condition', immunotherapy and antidepressive treatment. Int. J. Neuropsychopharmacol. 2002, 5:389-399.
    • (2002) Int. J. Neuropsychopharmacol. , vol.5 , pp. 389-399
    • Pollak, Y.1    Yirmiya, R.2
  • 7
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R., O'Connor J.C., Freund G.G., Johnson R.W., Kelley K.W. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci. 2008, 9:46-56.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 10
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: inflammation and the pathogenesis of depression
    • Raison C.L., Capuron L., Miller A.H. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol. 2006, 27:24-31.
    • (2006) Trends Immunol. , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 11
    • 84885231010 scopus 로고    scopus 로고
    • Pharmacological modulation of HPA axis in depression - new avenues for potential therapeutic benefits
    • Maric N.P., Adzic M. Pharmacological modulation of HPA axis in depression - new avenues for potential therapeutic benefits. Psychiatr. Danub. 2013, 25(3):299-305.
    • (2013) Psychiatr. Danub. , vol.25 , Issue.3 , pp. 299-305
    • Maric, N.P.1    Adzic, M.2
  • 12
    • 0023276493 scopus 로고
    • Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor
    • Sapolsky R., Rivier C., Yamamoto G., Plotsky P., Vale W. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science 1987, 238:522-524.
    • (1987) Science , vol.238 , pp. 522-524
    • Sapolsky, R.1    Rivier, C.2    Yamamoto, G.3    Plotsky, P.4    Vale, W.5
  • 13
    • 0022530255 scopus 로고
    • Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones
    • Besedovsky H., del Rey A., Sorkin E., Dinarello C.A. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 1986, 233:652-654.
    • (1986) Science , vol.233 , pp. 652-654
    • Besedovsky, H.1    del Rey, A.2    Sorkin, E.3    Dinarello, C.A.4
  • 14
    • 33845291521 scopus 로고    scopus 로고
    • Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression
    • Pace T.W., Hu F., Miller A.H. Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression. Brain Behav. Immun. 2007, 21:9-19.
    • (2007) Brain Behav. Immun. , vol.21 , pp. 9-19
    • Pace, T.W.1    Hu, F.2    Miller, A.H.3
  • 15
    • 4444333049 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    • Minghetti L. Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J. Neuropathol. Exp. Neurol. 2004, 63:901-910.
    • (2004) J. Neuropathol. Exp. Neurol. , vol.63 , pp. 901-910
    • Minghetti, L.1
  • 16
    • 33751378163 scopus 로고    scopus 로고
    • Hippocampal up-regulation of the cyclooxygenase-2 gene following neonatal clomipramine treatment (a model of depression)
    • Cassano P., Hidelgo A., Burgos V., Adris S., Argibay P. Hippocampal up-regulation of the cyclooxygenase-2 gene following neonatal clomipramine treatment (a model of depression). Pharmacogenomics J. 2006, 6:381-387.
    • (2006) Pharmacogenomics J. , vol.6 , pp. 381-387
    • Cassano, P.1    Hidelgo, A.2    Burgos, V.3    Adris, S.4    Argibay, P.5
  • 17
    • 57049151337 scopus 로고    scopus 로고
    • Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-beta
    • Sun H., Sheveleva E., Xu B., Inoue H., Bowden T.G., Chen Q.M. Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-beta. Am. J. Physiol. Cell Physiol. 2008, 295:915-922.
    • (2008) Am. J. Physiol. Cell Physiol. , vol.295 , pp. 915-922
    • Sun, H.1    Sheveleva, E.2    Xu, B.3    Inoue, H.4    Bowden, T.G.5    Chen, Q.M.6
  • 18
    • 70449714176 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor: role in depression and suicide
    • Dwivedi Y. Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatr. Dis. Treat. 2009, 5:433-449.
    • (2009) Neuropsychiatr. Dis. Treat. , vol.5 , pp. 433-449
    • Dwivedi, Y.1
  • 19
    • 0027522350 scopus 로고
    • Systemic interleukin-1 beta decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation
    • Lapchak P.A., Araujo D.M., Hefti F. Systemic interleukin-1 beta decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation. Neuroscience 1993, 53:297-301.
    • (1993) Neuroscience , vol.53 , pp. 297-301
    • Lapchak, P.A.1    Araujo, D.M.2    Hefti, F.3
  • 20
    • 0036889766 scopus 로고    scopus 로고
    • Cytokines and neuro-immune-endocrine interactions: a role for the hypothalamic-pituitary-adrenal revolving axis
    • Haddad J., Saade N.E., Safieh-Garabedian B. Cytokines and neuro-immune-endocrine interactions: a role for the hypothalamic-pituitary-adrenal revolving axis. J. Neuroimmunol. 2002, 133:1-19.
    • (2002) J. Neuroimmunol. , vol.133 , pp. 1-19
    • Haddad, J.1    Saade, N.E.2    Safieh-Garabedian, B.3
  • 21
    • 0017618768 scopus 로고
    • Depression: a new model sensitive to the antidepressant treatment
    • Porsolt R.D., Pichon M.L., Jalfre M. Depression: a new model sensitive to the antidepressant treatment. Nature 1977, 266:730-732.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Pichon, M.L.2    Jalfre, M.3
  • 22
    • 53549090423 scopus 로고    scopus 로고
    • Different behavioral effects of maprotiline and fluxilan in rats
    • Spasojevic N., Gavrilovic Lj, Dronjak S. Different behavioral effects of maprotiline and fluxilan in rats. Arch. Biol. Sci. 2008, 60:33-39.
    • (2008) Arch. Biol. Sci. , vol.60 , pp. 33-39
    • Spasojevic, N.1    Gavrilovic, Lj2    Dronjak, S.3
  • 25
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 26
    • 84862640477 scopus 로고    scopus 로고
    • Maternal deprivation in rats is associated with corticotrophin-releasing hormone (CRH) promoterhypomethylation and enhances CRH transcriptional responses to stress in adulthood
    • Chen J., Evans A.N., Liu Y., Honda M., Saavedra J.M., Aguilera G. Maternal deprivation in rats is associated with corticotrophin-releasing hormone (CRH) promoterhypomethylation and enhances CRH transcriptional responses to stress in adulthood. J. Neuroendocrinol. 2012, 24(7):1055-1064.
    • (2012) J. Neuroendocrinol. , vol.24 , Issue.7 , pp. 1055-1064
    • Chen, J.1    Evans, A.N.2    Liu, Y.3    Honda, M.4    Saavedra, J.M.5    Aguilera, G.6
  • 27
    • 77954874273 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor
    • Kino T., Jaffe H., Amin N.D., Chakrabarti M., Zheng Y.L., Chrousos G.P., Pan H.C. Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor. Mol. Endocrinol. 2010, 24:941-952.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 941-952
    • Kino, T.1    Jaffe, H.2    Amin, N.D.3    Chakrabarti, M.4    Zheng, Y.L.5    Chrousos, G.P.6    Pan, H.C.7
  • 28
    • 33847047204 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression in hypothalamic paraventricular nucleus in rats with heart failure: role of nuclear factor kappaB
    • Yu Y., Kang Y.M., Zhang Z.H., Wei S.G., Chu Y., Weiss R.M., Felder R.B. Increased cyclooxygenase-2 expression in hypothalamic paraventricular nucleus in rats with heart failure: role of nuclear factor kappaB. Hypertension 2007, 49(3):511-518.
    • (2007) Hypertension , vol.49 , Issue.3 , pp. 511-518
    • Yu, Y.1    Kang, Y.M.2    Zhang, Z.H.3    Wei, S.G.4    Chu, Y.5    Weiss, R.M.6    Felder, R.B.7
  • 29
    • 4444337502 scopus 로고    scopus 로고
    • Mathematics of quantitative kinetic PCR and the application of standard curves
    • Rutledge R., Cote C. Mathematics of quantitative kinetic PCR and the application of standard curves. Nucleic Acids Res. 2003, 31:e93.
    • (2003) Nucleic Acids Res. , vol.31 , pp. e93
    • Rutledge, R.1    Cote, C.2
  • 30
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T))method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T))method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 31
    • 0029962322 scopus 로고    scopus 로고
    • Endotoxin produces a depressive-like episode in rats
    • Yirmiya R. Endotoxin produces a depressive-like episode in rats. Brain Res. 1996, 711:163-174.
    • (1996) Brain Res. , vol.711 , pp. 163-174
    • Yirmiya, R.1
  • 32
    • 63349090404 scopus 로고    scopus 로고
    • Neurochemical and behavioral alterations in an inflammatory model of depression: sex differences exposed
    • Pitychoutis P.M., Nakamura K., Tsonis P.A., Papadopoulou-Daifoti Z. Neurochemical and behavioral alterations in an inflammatory model of depression: sex differences exposed. Neuroscience 2009, 159(4):1216-1232.
    • (2009) Neuroscience , vol.159 , Issue.4 , pp. 1216-1232
    • Pitychoutis, P.M.1    Nakamura, K.2    Tsonis, P.A.3    Papadopoulou-Daifoti, Z.4
  • 33
    • 0027241497 scopus 로고
    • Psychomotor retardation, anorexia, weight loss, sleep disturbances, and loss of energy: psychopathological correlates of hyperhaptoglobinemia during major depression
    • Maes M., Meltzer H.Y., Scharpe S., Cooreman W., Uyttenbroeck W., Suy E., Vandervorst C., Calabrese J., Raus J., Cosyns P. Psychomotor retardation, anorexia, weight loss, sleep disturbances, and loss of energy: psychopathological correlates of hyperhaptoglobinemia during major depression. Psychiatry Res. 1993, 47:229-241.
    • (1993) Psychiatry Res. , vol.47 , pp. 229-241
    • Maes, M.1    Meltzer, H.Y.2    Scharpe, S.3    Cooreman, W.4    Uyttenbroeck, W.5    Suy, E.6    Vandervorst, C.7    Calabrese, J.8    Raus, J.9    Cosyns, P.10
  • 35
    • 0036370277 scopus 로고    scopus 로고
    • Sexual dimorphism of neuroendocrine-immune interactions
    • Karger, Basel, Switzerland, R.C. Gaillard (Ed.)
    • Spinedi E., Gaillard R.C., Chisari A. Sexual dimorphism of neuroendocrine-immune interactions. Neuroendocrine Immune Interactions 2002, 91-107. Karger, Basel, Switzerland. R.C. Gaillard (Ed.).
    • (2002) Neuroendocrine Immune Interactions , pp. 91-107
    • Spinedi, E.1    Gaillard, R.C.2    Chisari, A.3
  • 36
    • 0032905515 scopus 로고    scopus 로고
    • Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action
    • Turnbull A.V., Rivier C.L. Regulation of the hypothalamic-pituitary-adrenal axis by cytokines: actions and mechanisms of action. Physiol. Rev. 1999, 79:1-71.
    • (1999) Physiol. Rev. , vol.79 , pp. 1-71
    • Turnbull, A.V.1    Rivier, C.L.2
  • 37
    • 1842470021 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide (LPS) modulates corticotropin-releasing hormone (CRH) content and release in the brain of juvenile and adult tilapia (Oreochromis mossambicus; Teleostei)
    • Pepels P.P., Bonga S.E., Balm P.H. Bacterial lipopolysaccharide (LPS) modulates corticotropin-releasing hormone (CRH) content and release in the brain of juvenile and adult tilapia (Oreochromis mossambicus; Teleostei). Exp. Biol. 2004, 207(Pt 25):4479-4488.
    • (2004) Exp. Biol. , vol.207 , pp. 4479-4488
    • Pepels, P.P.1    Bonga, S.E.2    Balm, P.H.3
  • 38
    • 0023231717 scopus 로고
    • Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1
    • Berkenbosch F., van Oers J., del Rey A., Tilders F., Besedovsky H. Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1. Science 1987, 238:524-526.
    • (1987) Science , vol.238 , pp. 524-526
    • Berkenbosch, F.1    van Oers, J.2    del Rey, A.3    Tilders, F.4    Besedovsky, H.5
  • 39
    • 36448961244 scopus 로고    scopus 로고
    • Treadmill exercise counteracts the suppressive effects of peripheral lipopolysaccharide on hippocampal neurogenesis and learning and memory
    • Wu C.W., Chen Y.C., Yu L., Chen H., Jen C.J., Huang A.M., Tsai H.J., Chang Y.T., Kuo Y.M. Treadmill exercise counteracts the suppressive effects of peripheral lipopolysaccharide on hippocampal neurogenesis and learning and memory. J. Neurochem. 2007, 103:2471-2481.
    • (2007) J. Neurochem. , vol.103 , pp. 2471-2481
    • Wu, C.W.1    Chen, Y.C.2    Yu, L.3    Chen, H.4    Jen, C.J.5    Huang, A.M.6    Tsai, H.J.7    Chang, Y.T.8    Kuo, Y.M.9
  • 40
    • 36148973919 scopus 로고    scopus 로고
    • Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotrophin and proopiomelanocortin in mouse brain
    • Schnydrig S., Korner L., Landweer S., Ernst B., Walker G., Otten U., Kunz D. Peripheral lipopolysaccharide administration transiently affects expression of brain-derived neurotrophic factor, corticotrophin and proopiomelanocortin in mouse brain. Neurosci. Lett. 2007, 429(1):69-73.
    • (2007) Neurosci. Lett. , vol.429 , Issue.1 , pp. 69-73
    • Schnydrig, S.1    Korner, L.2    Landweer, S.3    Ernst, B.4    Walker, G.5    Otten, U.6    Kunz, D.7
  • 41
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry. 2006, 59:1116-1127.
    • (2006) Biol. Psychiatry. , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 42
    • 77957359431 scopus 로고    scopus 로고
    • Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression
    • Kunugi H., Hor iH, Adachi N., Numakawa T. Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression. Psychiatry Clin. Neurosci. 2010, 64:447-459.
    • (2010) Psychiatry Clin. Neurosci. , vol.64 , pp. 447-459
    • Kunugi, H.1    Hor, iH2    Adachi, N.3    Numakawa, T.4
  • 43
    • 79952772473 scopus 로고    scopus 로고
    • Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes
    • Cortese G.P., Barrientos R.M., Maier S.F., Patterson S.L. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. J. Neurosci. 2011, 31:4274-4279.
    • (2011) J. Neurosci. , vol.31 , pp. 4274-4279
    • Cortese, G.P.1    Barrientos, R.M.2    Maier, S.F.3    Patterson, S.L.4
  • 44
    • 29144444066 scopus 로고    scopus 로고
    • Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats
    • Guan Z., Fang J. Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats. Brain Behav. Immun. 2006, 20:64-71.
    • (2006) Brain Behav. Immun. , vol.20 , pp. 64-71
    • Guan, Z.1    Fang, J.2
  • 46
    • 0037846419 scopus 로고    scopus 로고
    • Neuroimmune response to endogenous and exogenous pyrogens is differently modulated by sex steroids
    • Mouihate A., Pittman Q.J. Neuroimmune response to endogenous and exogenous pyrogens is differently modulated by sex steroids. Endocrinology 2003, 144:2454-2460.
    • (2003) Endocrinology , vol.144 , pp. 2454-2460
    • Mouihate, A.1    Pittman, Q.J.2
  • 47
    • 84905220400 scopus 로고    scopus 로고
    • Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia
    • eCollection 2014
    • Lei B., Mace B., Dawson H.N., Warner D.S., Laskowitz D.T., James M.L. Anti-inflammatory effects of progesterone in lipopolysaccharide-stimulated BV-2 microglia. PLOS ONE 2014, 9(7):e103969. eCollection 2014. 10.1371/journal.pone.0103969.
    • (2014) PLOS ONE , vol.9 , Issue.7 , pp. e103969
    • Lei, B.1    Mace, B.2    Dawson, H.N.3    Warner, D.S.4    Laskowitz, D.T.5    James, M.L.6
  • 48
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • Block M.L., Zecca L., Hong J.S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 2007, 8:57-69.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 49
    • 0036148669 scopus 로고    scopus 로고
    • The increase in TNF-alpha levels is implicated in NF-kappa B activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress
    • Madrigal J.L., Hurtado O., Moro M.A., Lizasoain I., Lorenzo P., Castrillo A., Boscá L., Leza J.C. The increase in TNF-alpha levels is implicated in NF-kappa B activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress. Neuropsychopharmacology 2002, 26(2):155-163.
    • (2002) Neuropsychopharmacology , vol.26 , Issue.2 , pp. 155-163
    • Madrigal, J.L.1    Hurtado, O.2    Moro, M.A.3    Lizasoain, I.4    Lorenzo, P.5    Castrillo, A.6    Boscá, L.7    Leza, J.C.8
  • 50
    • 84876114058 scopus 로고    scopus 로고
    • Cyclooxygenase-2-related signaling in the hypothalamus plays differential roles in response to various acute stresses
    • Ma Y., Matsuwaki T., Yamanouchi K., Nishihara M. Cyclooxygenase-2-related signaling in the hypothalamus plays differential roles in response to various acute stresses. Brain Res. 2013, 1508:23-33.
    • (2013) Brain Res. , vol.1508 , pp. 23-33
    • Ma, Y.1    Matsuwaki, T.2    Yamanouchi, K.3    Nishihara, M.4
  • 51
    • 6344265739 scopus 로고    scopus 로고
    • Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase
    • Szatmáry Z., Garabedian M.J., Vilcek J. Inhibition of glucocorticoid receptor-mediated transcriptional activation by p38 mitogen-activated protein (MAP) kinase. J. Biol. Chem. 2004, 279:43708-43711.
    • (2004) J. Biol. Chem. , vol.279 , pp. 43708-43711
    • Szatmáry, Z.1    Garabedian, M.J.2    Vilcek, J.3
  • 52
    • 0442272538 scopus 로고    scopus 로고
    • When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress related disorders
    • Raison C.L., Miller A.H. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress related disorders. Am. J. Psychiatry 2003, 160:1554-1565.
    • (2003) Am. J. Psychiatry , vol.160 , pp. 1554-1565
    • Raison, C.L.1    Miller, A.H.2
  • 53
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids-mechanisms for old drugs
    • Rhen T., Cidlowski J.A. Antiinflammatory action of glucocorticoids-mechanisms for old drugs. N. Engl. J. Med. 2005, 353:1711-1723.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 54
    • 34247385436 scopus 로고    scopus 로고
    • Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression
    • Zhao X., Zhang Y., Strong R., Zhang J., Grotta J.C., Aronowski J. Distinct patterns of intracerebral hemorrhage-induced alterations in NF-kappaB subunit, iNOS, and COX-2 expression. J. Neurochem. 2007, 101:652-663.
    • (2007) J. Neurochem. , vol.101 , pp. 652-663
    • Zhao, X.1    Zhang, Y.2    Strong, R.3    Zhang, J.4    Grotta, J.C.5    Aronowski, J.6
  • 55
    • 84857850658 scopus 로고    scopus 로고
    • The emerging role of C/EBPs in glucocorticoid signaling: lessons from the lung
    • Roos A.B., Nord M. The emerging role of C/EBPs in glucocorticoid signaling: lessons from the lung. J. Endocrinol. 2012, 212(3):291-305.
    • (2012) J. Endocrinol. , vol.212 , Issue.3 , pp. 291-305
    • Roos, A.B.1    Nord, M.2
  • 56
    • 57049151337 scopus 로고    scopus 로고
    • Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-beta
    • Sun H., Sheveleva E., Xu B., Inoue H., Bowden T.G., Chen Q.M. Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-beta. Am. J. Physiol. Cell Physiol. 2008, 295(4):C915-C922.
    • (2008) Am. J. Physiol. Cell Physiol. , vol.295 , Issue.4 , pp. C915-C922
    • Sun, H.1    Sheveleva, E.2    Xu, B.3    Inoue, H.4    Bowden, T.G.5    Chen, Q.M.6
  • 57
    • 79953065448 scopus 로고    scopus 로고
    • Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity
    • Milatovic D., Montine T.J., Aschner M. Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity. Neurotoxicology 2011, 32:312-319.
    • (2011) Neurotoxicology , vol.32 , pp. 312-319
    • Milatovic, D.1    Montine, T.J.2    Aschner, M.3
  • 58
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: structure, function and regulation
    • Ramji D.P., Foka P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 2002, 365:561-575.
    • (2002) Biochem. J. , vol.365 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 59
  • 60
    • 60149095739 scopus 로고    scopus 로고
    • Identification of neuronal target genes for CCAAT/enhancer binding proteins
    • Kfoury N., Kapatos G. Identification of neuronal target genes for CCAAT/enhancer binding proteins. Mol. Cell. Neurosci. 2009, 40(3):313-327.
    • (2009) Mol. Cell. Neurosci. , vol.40 , Issue.3 , pp. 313-327
    • Kfoury, N.1    Kapatos, G.2


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