Maternal Deprivation in Rats is Associated with Corticotrophin-Releasing Hormone (CRH) Promoter Hypomethylation and Enhances CRH Transcriptional Responses to Stress in Adulthood

Journal of Neuroendocrinology

Volumn 24, Issue 7, 2012, Pages 1055-1064

  Chen, J ^a   Evans, A N ^a   Liu, Y ^a   Honda, M ^b   Saavedra, J M ^b   Aguilera, G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Corticotrophin releasing hormone; DNA methylation; Hypothalamic pituitary adrenal axis; Maternal deprivation

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; FORSKOLIN; OLIGONUCLEOTIDE;

ADRENAL GLAND; ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN BINDING; ARTICLE; BODY WEIGHT; CENTRAL NUCLEUS (AMYGDALA); CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CPG ISLAND; CYCLIC AMP RESPONSIVE ELEMENT; DNA METHYLATION; EARLY LIFE STRESS; FEMALE; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION STRESS; MALE; MATERNAL CARE; MATERNAL DEPRIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RAT; THYMUS; TRANSCRIPTION INITIATION;

ADRENAL GLANDS; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; CORTICOTROPIN-RELEASING HORMONE; DNA METHYLATION; DOWN-REGULATION; FEMALE; MALE; MATERNAL DEPRIVATION; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; THYMUS GLAND; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84862640477     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2012.02306.x     Document Type: Article

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