A novel autoregulatory loop between the Gcn2-Atf4 pathway and L-Proline metabolism controls stem cell identity

Cell Death and Differentiation

Volumn 22, Issue 7, 2015, Pages 1094-1105

  D'Aniello, C ^a   Fico, A ^a   Casalino, L ^a   Guardiola, O ^a   Di Napoli, G ^a   Cermola, F ^a   De Cesare, D ^a   Tate R ^a   Cobellis, G ^b   Patriarca, E J ^a   Minchiotti, G ^a  

^a INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; AMINO ACID TRANSFER RNA LIGASE; GENERAL CONTROL NONREPRESSED 2; HALOFUGINONE; PROLINE; PROLYL TRANSFER RNA SYNTHETASE; PROTEIN KINASE; UNCLASSIFIED DRUG; ATF4 PROTEIN, MOUSE; EIF2AK4 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE;

AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; AUTOREGULATION; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ENZYME INHIBITION; FEEDBACK SYSTEM; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; NUTRIENT; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; METABOLISM; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; EMBRYONIC STEM CELLS; FEEDBACK, PHYSIOLOGICAL; MICE; PROLINE; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 84930575113     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.24     Document Type: Article

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