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Volumn 138, Issue 3, 2015, Pages 632-643

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis

(46)  Goris, An a   Pauwels, Ine a   Gustavsen, Marte W b,c   Van Son, Brechtje d   Hilven, Kelly a   Bos, Steffan D b,c   Celius, Elisabeth Gulowsen b   Berg Hansen, Pal b,c   Aarseth, Jan e   Myhr, Kjell Morten e,f   D'Alfonso, Sandra g   Barizzone, Nadia g   Leone, Maurizio A g,h   Boneschi, Filippo Martinelli i   Sorosina, Melissa i   Liberatore, Giuseppe i   Kockum, Ingrid j   Olsson, Tomas j   Hillert, Jan j   Alfredsson, Lars j   more..


Author keywords

CSF; Genetics; Immunoglobulin; Multiple sclerosis; Oligoclonal bands

Indexed keywords

HLA DQA1 ANTIGEN; HLA DRB1 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; OLIGOCLONAL BAND; ELAC1 PROTEIN, HUMAN; SMAD4 PROTEIN; SMAD4 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

EID: 84930571293     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awu405     Document Type: Article
Times cited : (51)

References (51)
  • 1
    • 79960934301 scopus 로고    scopus 로고
    • Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis
    • Allanore Y, Saad M, Dieude P, Avouac J, Distler JH, Amouyel P, et al. Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet 2011; 7: e1002091.
    • (2011) PLoS Genet , vol.7 , pp. e1002091
    • Allanore, Y.1    Saad, M.2    Dieude, P.3    Avouac, J.4    Distler, J.H.5    Amouyel, P.6
  • 2
    • 84887405358 scopus 로고    scopus 로고
    • Increased disease severity in non-Western immigrants with multiple sclerosis in Oslo, Norway
    • Berg-Hansen P, Smestad C, Sandvik L, Harbo HF, Celius EG. Increased disease severity in non-Western immigrants with multiple sclerosis in Oslo, Norway. Eur J Neurol 2013; 20: 1546-52.
    • (2013) Eur J Neurol , vol.20 , pp. 1546-1552
    • Berg-Hansen, P.1    Smestad, C.2    Sandvik, L.3    Harbo, H.F.4    Celius, E.G.5
  • 3
    • 84873379575 scopus 로고    scopus 로고
    • Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis
    • Buck D, Albrecht E, Aslam M, Goris A, Hauenstein N, Jochim A, et al. Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis. Ann Neurol 2012; 73: 86-94.
    • (2012) Ann Neurol , vol.73 , pp. 86-94
    • Buck, D.1    Albrecht, E.2    Aslam, M.3    Goris, A.4    Hauenstein, N.5    Jochim, A.6
  • 4
    • 0035164119 scopus 로고    scopus 로고
    • Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis
    • Cepok S, Jacobsen M, Schock S, Omer B, Jaekel S, Boddeker I, et al. Patterns of cerebrospinal fluid pathology correlate with disease progression in multiple sclerosis. Brain 2001; 124 (Pt 11): 2169-76.
    • (2001) Brain , vol.124 , pp. 2169-2176
    • Cepok, S.1    Jacobsen, M.2    Schock, S.3    Omer, B.4    Jaekel, S.5    Boddeker, I.6
  • 5
    • 21944448962 scopus 로고    scopus 로고
    • Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis
    • Cepok S, Rosche B, Grummel V, Vogel F, Zhou D, Sayn J, et al. Short-lived plasma blasts are the main B cell effector subset during the course of multiple sclerosis. Brain 2005; 128 (Pt 7): 1667-76.
    • (2005) Brain , vol.128 , pp. 1667-1676
    • Cepok, S.1    Rosche, B.2    Grummel, V.3    Vogel, F.4    Zhou, D.5    Sayn, J.6
  • 6
    • 54149084585 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Compston A, Coles A. Multiple sclerosis. Lancet 2008; 372: 1502-17.
    • (2008) Lancet , vol.372 , pp. 1502-1517
    • Compston, A.1    Coles, A.2
  • 7
    • 79953314023 scopus 로고    scopus 로고
    • HLA∗IMP-an integrated framework for imputing classical HLA alleles from SNP genotypes
    • Dilthey AT, Moutsianas L, Leslie S, McVean G. HLA∗IMP-an integrated framework for imputing classical HLA alleles from SNP genotypes. Bioinformatics 2011; 27: 968-72.
    • (2011) Bioinformatics , vol.27 , pp. 968-972
    • Dilthey, A.T.1    Moutsianas, L.2    Leslie, S.3    McVean, G.4
  • 8
    • 84879910017 scopus 로고    scopus 로고
    • Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: A meta-analysis of prevalence, prognosis and effect of latitude
    • Dobson R, Ramagopalan S, Davis A, Giovannoni G. Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude. J Neurol Neurosurg Psychiatry 2013; 84: 909-14.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , pp. 909-914
    • Dobson, R.1    Ramagopalan, S.2    Davis, A.3    Giovannoni, G.4
  • 10
    • 0032581195 scopus 로고    scopus 로고
    • The significance of oligoclonal bands in multiple sclerosis in Japan: Relevance of immunogenetic backgrounds
    • Fukazawa T, Kikuchi S, Sasaki H, Hamada K, Hamada T, Miyasaka K, et al. The significance of oligoclonal bands in multiple sclerosis in Japan: relevance of immunogenetic backgrounds. J Neurol Sci 1998; 158: 209-14.
    • (1998) J Neurol Sci , vol.158 , pp. 209-214
    • Fukazawa, T.1    Kikuchi, S.2    Sasaki, H.3    Hamada, K.4    Hamada, T.5    Miyasaka, K.6
  • 11
    • 0038608366 scopus 로고    scopus 로고
    • In primary Sjogren's syndrome, HLA class II is associated exclusively with autoantibody production and spreading of the autoimmune response
    • Gottenberg JE, Busson M, Loiseau P, Cohen-Solal J, Lepage V, Charron D, et al. In primary Sjogren's syndrome, HLA class II is associated exclusively with autoantibody production and spreading of the autoimmune response. Arthritis Rheum 2003; 48: 2240-5.
    • (2003) Arthritis Rheum , vol.48 , pp. 2240-2245
    • Gottenberg, J.E.1    Busson, M.2    Loiseau, P.3    Cohen-Solal, J.4    Lepage, V.5    Charron, D.6
  • 13
    • 0033818428 scopus 로고    scopus 로고
    • Incidence of CSF abnormalities in siblings of multiple sclerosis patients and unrelated controls
    • Haghighi S, Andersen O, Rosengren L, Bergstrom T, Wahlstrom J, Nilsson S. Incidence of CSF abnormalities in siblings of multiple sclerosis patients and unrelated controls. J Neurol 2000; 247: 616-22.
    • (2000) J Neurol , vol.247 , pp. 616-622
    • Haghighi, S.1    Andersen, O.2    Rosengren, L.3    Bergstrom, T.4    Wahlstrom, J.5    Nilsson, S.6
  • 14
    • 84899048957 scopus 로고    scopus 로고
    • Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis
    • Harbo HF, Isobe N, Berg-Hansen P, Bos SD, Caillier SJ, Gustavsen MW, et al. Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis. Mult Scler 2014; 20: 660-8.
    • (2014) Mult Scler , vol.20 , pp. 660-668
    • Harbo, H.F.1    Isobe, N.2    Berg-Hansen, P.3    Bos, S.D.4    Caillier, S.J.5    Gustavsen, M.W.6
  • 16
    • 80053140858 scopus 로고    scopus 로고
    • TGF-beta signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE
    • Huss DJ, Winger RC, Cox GM, Guerau-de-Arellano M, Yang Y, Racke MK, et al. TGF-beta signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE. Eur J Immunol 2011; 41: 2987-96.
    • (2011) Eur J Immunol , vol.41 , pp. 2987-2996
    • Huss, D.J.1    Winger, R.C.2    Cox, G.M.3    Guerau-De-Arellano, M.4    Yang, Y.5    Racke, M.K.6
  • 17
    • 67649884741 scopus 로고    scopus 로고
    • The significance of oligoclonal bands in multiple sclerosis: Relevance of demographic and clinical features, and immunogenetic backgrounds
    • Idiman E, Ozakbas S, Dogan Y, Kosehasanogullari G. The significance of oligoclonal bands in multiple sclerosis: relevance of demographic and clinical features, and immunogenetic backgrounds. J Neuroimmunol 2009; 212: 121-4.
    • (2009) J Neuroimmunol , vol.212 , pp. 121-124
    • Idiman, E.1    Ozakbas, S.2    Dogan, Y.3    Kosehasanogullari, G.4
  • 18
    • 33749023292 scopus 로고    scopus 로고
    • Multiple sclerosis with and without CSF bands: Clinically indistinguishable but immu-nogenetically distinct
    • Imrell K, Landtblom AM, Hillert J, Masterman T. Multiple sclerosis with and without CSF bands: clinically indistinguishable but immu-nogenetically distinct. Neurology 2006; 67: 1062-4.
    • (2006) Neurology , vol.67 , pp. 1062-1064
    • Imrell, K.1    Landtblom, A.M.2    Hillert, J.3    Masterman, T.4
  • 19
    • 22144451846 scopus 로고    scopus 로고
    • Clinical and genetic characteristics of diabetic patients with high-titer (410, 000 U/ml) of antibodies to glutamic acid decarb-oxylase
    • Ishii M, Hasegawa G, Fukui M, Obayashi H, Ohta M, Ogata M, et al. Clinical and genetic characteristics of diabetic patients with high-titer (410, 000 U/ml) of antibodies to glutamic acid decarb-oxylase. Immunol Lett 2005; 99: 180-5.
    • (2005) Immunol Lett , vol.99 , pp. 180-185
    • Ishii, M.1    Hasegawa, G.2    Fukui, M.3    Obayashi, H.4    Ohta, M.5    Ogata, M.6
  • 20
    • 0015492877 scopus 로고
    • HL-A antigens and multiple sclerosis
    • Jersild C, Svejgaard A, Fog T. HL-A antigens and multiple sclerosis. Lancet 1972; 1: 1240-1.
    • (1972) Lancet , vol.1 , pp. 1240-1241
    • Jersild, C.1    Svejgaard, A.2    Fog, T.3
  • 21
    • 0037465464 scopus 로고    scopus 로고
    • HLA-related subpopulations of MS in Japanese with and without oligoclonal IgG bands. Human leukocyte antigen
    • Kikuchi S, Fukazawa T, Niino M, Yabe I, Miyagishi R, Hamada T, et al. HLA-related subpopulations of MS in Japanese with and without oligoclonal IgG bands. Human leukocyte antigen. Neurology 2003; 60: 647-51.
    • (2003) Neurology , vol.60 , pp. 647-651
    • Kikuchi, S.1    Fukazawa, T.2    Niino, M.3    Yabe, I.4    Miyagishi, R.5    Hamada, T.6
  • 23
    • 84879052306 scopus 로고    scopus 로고
    • Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients
    • Leone MA, Barizzone N, Esposito F, Lucenti A, Harbo HF, Goris A, et al. Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. PLoS One 2013; 8: e64408.
    • (2013) PLoS One , vol.8 , pp. e64408
    • Leone, M.A.1    Barizzone, N.2    Esposito, F.3    Lucenti, A.4    Harbo, H.F.5    Goris, A.6
  • 24
    • 33750604563 scopus 로고    scopus 로고
    • Oligoclonal bands in multiple sclerosis cerebro-spinal fluid: An update on methodology and clinical usefulness
    • Link H, Huang YM. Oligoclonal bands in multiple sclerosis cerebro-spinal fluid: an update on methodology and clinical usefulness. J Neuroimmunol 2006; 180: 17-28.
    • (2006) J Neuroimmunol , vol.180 , pp. 17-28
    • Link, H.1    Huang, Y.M.2
  • 25
    • 34249700046 scopus 로고    scopus 로고
    • Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
    • Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopolo M, et al. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 2007; 130 (Pt 4): 1089-104.
    • (2007) Brain , vol.130 , pp. 1089-1104
    • Magliozzi, R.1    Howell, O.2    Vora, A.3    Serafini, B.4    Nicholas, R.5    Puopolo, M.6
  • 26
    • 21844465739 scopus 로고    scopus 로고
    • Correlation between the IgG index, oligoclonal bands in CSF, and the diagnosis of demyeli-nating diseases
    • Mayringer I, Timeltaler B, Deisenhammer F. Correlation between the IgG index, oligoclonal bands in CSF, and the diagnosis of demyeli-nating diseases. Eur J Neurol 2005; 12: 527-30.
    • (2005) Eur J Neurol , vol.12 , pp. 527-530
    • Mayringer, I.1    Timeltaler, B.2    Deisenhammer, F.3
  • 27
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50: 121-7.
    • (2001) Ann Neurol , vol.50 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3    Goodkin, D.4    Hartung, H.P.5    Lublin, F.D.6
  • 28
    • 78650967701 scopus 로고    scopus 로고
    • TGF-beta signaling is altered in the peripheral blood of subjects with multiple sclerosis
    • Meoli EM, Oh U, Grant CW, Jacobson S. TGF-beta signaling is altered in the peripheral blood of subjects with multiple sclerosis. J Neuroimmunol 2010; 230: 164-8.
    • (2010) J Neuroimmunol , vol.230 , pp. 164-168
    • Meoli, E.M.1    Oh, U.2    Grant, C.W.3    Jacobson, S.4
  • 29
    • 84874604770 scopus 로고    scopus 로고
    • Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk al-leles
    • Mero IL, Gustavsen MW, Saether HS, Flam ST, Berg-Hansen P, Sondergaard HB, et al. Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk al-leles. PLoS One 2013; 8: e58352.
    • (2013) PLoS One , vol.8 , pp. e58352
    • Mero, I.L.1    Gustavsen, M.W.2    Saether, H.S.3    Flam, S.T.4    Berg-Hansen, P.5    Sondergaard, H.B.6
  • 30
    • 84902350020 scopus 로고    scopus 로고
    • "Masked" and overt autoantibodies specific to the DPD epitope of 65 kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved beta cell functional reserve in Ketosis-Prone Diabetes
    • Oak S, Gaur LK, Radtke J, Patel R, Iyer D, Ram N, et al. "Masked" and overt autoantibodies specific to the DPD epitope of 65 kDa glutamate decarboxylase (GAD65-DPD) are associated with preserved beta cell functional reserve in Ketosis-Prone Diabetes. J Clin Endocrinol Metab 2014; 99: E1040-4.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E1040-E1044
    • Oak, S.1    Gaur, L.K.2    Radtke, J.3    Patel, R.4    Iyer, D.5    Ram, N.6
  • 31
    • 84897018997 scopus 로고    scopus 로고
    • Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study
    • Orozco G, Viatte S, Bowes J, Martin P, Wilson AG, Morgan AW, et al. Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. Arthritis Rheumatol 2014; 66: 24-30.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 24-30
    • Orozco, G.1    Viatte, S.2    Bowes, J.3    Martin, P.4    Wilson, A.G.5    Morgan, A.W.6
  • 33
    • 84873383815 scopus 로고    scopus 로고
    • Immunoglobulin GM allotypes in multiple sclerosis
    • Pandey JP. Immunoglobulin GM allotypes in multiple sclerosis. Ann Neurol 2013; 73: 148.
    • (2013) Ann Neurol , vol.73 , pp. 148
    • Pandey, J.P.1
  • 34
    • 15844392414 scopus 로고    scopus 로고
    • Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching
    • Park SR, Seo GY, Choi AJ, Stavnezer J, Kim PH. Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching. Eur J Immunol 2005; 35: 946-56.
    • (2005) Eur J Immunol , vol.35 , pp. 946-956
    • Park, S.R.1    Seo, G.Y.2    Choi, A.J.3    Stavnezer, J.4    Kim, P.H.5
  • 35
    • 80052311755 scopus 로고    scopus 로고
    • Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases
    • Plagnol V, Howson JM, Smyth DJ, Walker N, Hafler JP, Wallace C, et al. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet 2011; 7: e1002216.
    • (2011) PLoS Genet , vol.7 , pp. e1002216
    • Plagnol, V.1    Howson, J.M.2    Smyth, D.J.3    Walker, N.4    Hafler, J.P.5    Wallace, C.6
  • 37
  • 38
    • 77951765348 scopus 로고    scopus 로고
    • Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
    • Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, et al. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet 2010; 42: 426-9.
    • (2010) Nat Genet , vol.42 , pp. 426-429
    • Radstake, T.R.1    Gorlova, O.2    Rueda, B.3    Martin, J.E.4    Alizadeh, B.Z.5    Palomino-Morales, R.6
  • 39
    • 34347407334 scopus 로고    scopus 로고
    • Higher IgG index found in African Americans versus Caucasians with multiple sclerosis
    • Rinker JR, Trinkaus K II, Naismith RT, Cross AH. Higher IgG index found in African Americans versus Caucasians with multiple sclerosis. Neurology 2007; 69: 68-72.
    • (2007) Neurology , vol.69 , pp. 68-72
    • Rinker, J.R.1    Trinkaus, K.I.I.2    Naismith, R.T.3    Cross, A.H.4
  • 40
    • 80052814497 scopus 로고    scopus 로고
    • Association of HLA-DRB1∗15 allele and CSF oligoclonal bands in a Spanish multiple sclerosis cohort
    • Romero-Pinel L, Martinez-Yelamos S, Bau L, Matas E, Gubieras L, Maria Pujal J, et al. Association of HLA-DRB1∗15 allele and CSF oligoclonal bands in a Spanish multiple sclerosis cohort. Eur J Neurol 2011; 18: 1258-62.
    • (2011) Eur J Neurol , vol.18 , pp. 1258-1262
    • Romero-Pinel, L.1    Martinez-Yelamos, S.2    Bau, L.3    Matas, E.4    Gubieras, L.5    Maria Pujal, J.6
  • 41
    • 20144387016 scopus 로고    scopus 로고
    • Multiple sclerosis severity score: Using disability and disease duration to rate disease severity
    • Roxburgh RH, Seaman SR, Masterman T, Hensiek AE, Sawcer SJ, Vukusic S, et al. Multiple sclerosis severity score: using disability and disease duration to rate disease severity. Neurology 2005; 64: 1144-51.
    • (2005) Neurology , vol.64 , pp. 1144-1151
    • Roxburgh, R.H.1    Seaman, S.R.2    Masterman, T.3    Hensiek, A.E.4    Sawcer, S.J.5    Vukusic, S.6
  • 42
    • 84873485653 scopus 로고    scopus 로고
    • A Genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)
    • Rubicz R, Yolken R, Drigalenko E, Carless MA, Dyer TD, Bauman L, et al. A Genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1). PLoS Genet 2013; 9: e1003147.
    • (2013) PLoS Genet , vol.9 , pp. e1003147
    • Rubicz, R.1    Yolken, R.2    Drigalenko, E.3    Carless, M.A.4    Dyer, T.D.5    Bauman, L.6
  • 43
    • 0032943375 scopus 로고    scopus 로고
    • Cerebrospinal fluid abnormalities in a phase III trial of Avonex (IFNbeta-1a) for relapsing multiple sclerosis. The multiple sclerosis collaborative research group
    • Rudick RA, Cookfair DL, Simonian NA, Ransohoff RM, Richert JR, Jacobs LD, et al. Cerebrospinal fluid abnormalities in a phase III trial of Avonex (IFNbeta-1a) for relapsing multiple sclerosis. The multiple sclerosis collaborative research group. J Neuroimmunol 1999; 93: 8-14.
    • (1999) J Neuroimmunol , vol.93 , pp. 8-14
    • Rudick, R.A.1    Cookfair, D.L.2    Simonian, N.A.3    Ransohoff, R.M.4    Richert, J.R.5    Jacobs, L.D.6
  • 45
    • 84901344743 scopus 로고    scopus 로고
    • JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants
    • Sundqvist E, Buck D, Warnke C, Albrecht E, Gieger C, Khademi M, et al. JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS Pathog 2014; 10: e1004084.
    • (2014) PLoS Pathog , vol.10 , pp. e1004084
    • Sundqvist, E.1    Buck, D.2    Warnke, C.3    Albrecht, E.4    Gieger, C.5    Khademi, M.6
  • 46
    • 73249122274 scopus 로고    scopus 로고
    • Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases
    • The International MHC and Autoimmunity Genetics Network.
    • The International MHC and Autoimmunity Genetics Network. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc Natl Acad Sci USA 2009; 106: 18680-5.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18680-18685
  • 47
    • 84887058596 scopus 로고    scopus 로고
    • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
    • The International Multiple Sclerosis Genetics Consortium.
    • The International Multiple Sclerosis Genetics Consortium. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet 2013; 45: 1353-60.
    • (2013) Nat Genet , vol.45 , pp. 1353-1360
  • 48
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • The International Multiple Sclerosis Genetics Consortium and The Wellcome Trust Case Control Consortium 2. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476: 214-9.
    • (2011) Nature , vol.476 , pp. 214-219
  • 49
    • 41549098712 scopus 로고    scopus 로고
    • Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis?
    • Tintore M, Rovira A, Rio J, Tur C, Pelayo R, Nos C, et al. Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis? Neurology 2008; 70 (13 Pt 2): 1079-83.
    • (2008) Neurology , vol.70 , Issue.13 , pp. 1079-1083
    • Tintore, M.1    Rovira, A.2    Rio, J.3    Tur, C.4    Pelayo, R.5    Nos, C.6
  • 50
    • 71249156005 scopus 로고    scopus 로고
    • Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australian multiple sclerosis cohort
    • Wu JS, Qiu W, Castley A, James I, Joseph J, Christiansen FT, et al. Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australian multiple sclerosis cohort. J Neurol Sci 2009; 288: 63-7.
    • (2009) J Neurol Sci , vol.288 , pp. 63-67
    • Wu, J.S.1    Qiu, W.2    Castley, A.3    James, I.4    Joseph, J.5    Christiansen, F.T.6
  • 51
    • 84929941176 scopus 로고    scopus 로고
    • Genetic and infectious profiles influence cerebrospinal fluid IgG abnormality in Japanese multiple sclerosis patients
    • Yoshimura S, Isobe N, Matsushita T, Masaki K, Sato S, Kawano Y, et al. Genetic and infectious profiles influence cerebrospinal fluid IgG abnormality in Japanese multiple sclerosis patients. PLoS One 2014; 9: e95367.
    • (2014) PLoS One , vol.9 , pp. e95367
    • Yoshimura, S.1    Isobe, N.2    Matsushita, T.3    Masaki, K.4    Sato, S.5    Kawano, Y.6


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