Association of HLA-DRB1*15 allele and CSF oligoclonal bands in a Spanish multiple sclerosis cohort

European Journal of Neurology

Volumn 18, Issue 10, 2011, Pages 1258-1262

  Romero Pinel, L ^a   Martinez Yelamos S ^a   Bau, L ^a   Matas, E ^a   Gubieras, L ^a   Maria Pujal J ^a   Morandeira, F ^a   Bas, J ^a   Arbizu, T ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Genetics; HLA; Immunology; Multiple sclerosis; Oligoclonal bands; Phenotype

Indexed keywords

HLA DR ANTIGEN; IMMUNOGLOBULIN G; OLIGOCLONAL BAND;

ADULT; ARTICLE; CEREBROSPINAL FLUID; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL;

ADULT; ALLELES; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HLA-DRB1 CHAINS; HUMANS; IMMUNOGLOBULIN G; MALE; MULTIPLE SCLEROSIS; OLIGOCLONAL BANDS; POLYMORPHISM, GENETIC; PREVALENCE; SPAIN;

EID: 80052814497     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2011.03379.x     Document Type: Article

References (16)

1. Schmidt H, Williamson D, Ashley-Koch A. HLA-DR15 haplotype and multiple sclerosis: a HuGE review. Am J Epidemiol 2007; 165: 1097-1109.
2. Freedman MS, Thompson EJ, Deisenhammer F, et al. Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement. Arch Neurol 2005; 62: 865-870.
3. Awad A, Hemmer B, Hartung HP, Kieseier B, Bennett JL, Stuve O. Analyses of cerebrospinal fluid in the diagnosis and monitoring of multiple sclerosis. J Neuroimmunol 2010; 219: 1-7.
4. Link H, Huang YM. Oligoclonal bands in multiple sclerosis cerebrospinal fluid: an update on methodology and clinical usefulness. J Neuroimmunol 2006; 180: 17-28.
5. Kikuchi S, Fukazawa T, Niino M, et al. HLA-related subpopulations of MS in Japanese with and without oligoclonal IgG bands. Neurology 2003; 60: 647-651.
6. Wu JS, Qiu W, Castley A, et al. Presence of CSF oligoclonal bands (OCB) is associated with the HLA-DRB1 genotype in a West Australia multiple sclerosis cohort. J Neurol Sci 2010; 288: 63-67.
7. Imrell K, Landtblom AM, Hillert J, Masterman T. Multiple sclerosis with and without CSF bands: clinically indistinguishable but immunogenetically distinct. Neurology 2006; 67: 1062-1064.
8. Confavreux C, Compston DA, Hommes OR, Mcdonald WI, Thompson AJ. EDMUS, a European database for multiple sclerosis. J Neurol Neurosurg Psychiatry 1992; 55: 671-676.
9. Romero-Pinel L, Pujal JM, Martínez-Yélamos S, et al. HLA-DRB1: genetic susceptibility and disability progression in a Spanish multiple sclerosis population. Eur J Neurol 2011; 18: 337-342.
10. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 2005; 58: 840-846.
11. Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2hours: an alternative serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992; 39: 225-235.
12. Walker RW, Keir G, Johnson MH, Thompson EJ. A rapid method for detecting oligoclonal IgG in unconcentrated CSF, by agarose isoelectric focusing, transfer to cellulose nitrate and immunoperoxidase staining. J Neuroimmunol 1983; 4: 141-148.
13. Idiman E, Ozakbas S, Dogan Y, Kosehasanogullari G. The significance of oligoclonal bands in multiple sclerosis: relevance of demographic and clinical features, and immunogenetic backgrounds. J Neuroimmunol 2009; 212: 121-124.
14. Tintoré M, Rovira A, Río J, et al. Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis? Neurology 2008; 70: 1079-1083.
15. Sellebjerg F, Jensen J, Madsen HO, Svejgaard A. HLA DRB1*1501 and intrathecal inflammation in multiple sclerosis. Tissue Antigens 2000; 55: 312-318.
16. Callander M, Haghighi S, Landtblom AM, et al. Multiple sclerosis immunopathic trait and HLA-DR(2)15 as independent risk factors in multiple sclerosis. Mult Scler 2007; 13: 441-445.