메뉴 건너뛰기




Volumn 55, Issue 3, 2015, Pages 609-617

Quercetin Glycosides Induced Neuroprotection by Changes in the Gene Expression in a Cellular Model of Parkinson’s Disease

Author keywords

6 Hydroxydopamine; Flavonoids; Parkin; Parkinson s disease

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; GLYCOSIDE; MICROTUBULE ASSOCIATED PROTEIN; OXIDOPAMINE; PARKIN; QUERCETIN; RUTOSIDE; SP22 PROTEIN, RAT; UBIQUITIN PROTEIN LIGASE; UBIQUITIN THIOLESTERASE;

EID: 84930473619     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0400-x     Document Type: Article
Times cited : (50)

References (71)
  • 1
    • 3242890363 scopus 로고    scopus 로고
    • Structural and functional analysis of ataxin-2 and ataxin-3
    • COI: 1:CAS:528:DC%2BD2cXmsFCitrs%3D, PID: 15265035
    • Albrecht M, Golatta M, Wüllner U et al (2004) Structural and functional analysis of ataxin-2 and ataxin-3. Eur J Biochem 271(15):3155–3170
    • (2004) Eur J Biochem , vol.271 , Issue.15 , pp. 3155-3170
    • Albrecht, M.1    Golatta, M.2    Wüllner, U.3
  • 2
    • 0032768571 scopus 로고    scopus 로고
    • Intradermal transfer of caspase-1 (CASP1) DNA into mouse dissects: role of CASP1 in interleukin-1β associated skin inflammation and apoptotic cell death
    • Asahi K, Mizutani H, Miura M et al (1999) Intradermal transfer of caspase-1 (CASP1) DNA into mouse dissects: role of CASP1 in interleukin-1β associated skin inflammation and apoptotic cell death. J Dermatol Sci 2:49–58
    • (1999) J Dermatol Sci , vol.2 , pp. 49-58
    • Asahi, K.1    Mizutani, H.2    Miura, M.3
  • 3
    • 46749094970 scopus 로고    scopus 로고
    • Neurochemical characterization of tyrosine hydroxylase-immunoreactive interneurons in the developing rat cerebral cortex
    • COI: 1:CAS:528:DC%2BD1cXosVOku7w%3D, PID: 18589406
    • Asmus SE, Anderson EK, Ball MW (2008) Neurochemical characterization of tyrosine hydroxylase-immunoreactive interneurons in the developing rat cerebral cortex. Brain Res 1222:95–105
    • (2008) Brain Res , vol.1222 , pp. 95-105
    • Asmus, S.E.1    Anderson, E.K.2    Ball, M.W.3
  • 4
    • 84939878309 scopus 로고    scopus 로고
    • Acute hypoxia-inducible factor Egln1 inactivation protects against ischemia-reperfusion injury by regulation of glucose oxidation and reactive oxygen species generation
    • Baik A, Olenchock B, Moslehi J et al (2013) Acute hypoxia-inducible factor Egln1 inactivation protects against ischemia-reperfusion injury by regulation of glucose oxidation and reactive oxygen species generation. J Am Coll Cardiol 6:10S
    • (2013) J Am Coll Cardiol , vol.6 , pp. 10S
    • Baik, A.1    Olenchock, B.2    Moslehi, J.3
  • 5
    • 10744224738 scopus 로고    scopus 로고
    • The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson’s disease
    • PID: 14662519
    • Bandopadhyay R, Kingsbury AE, Cookson MR et al (2004) The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson’s disease. Brain 127:420–430
    • (2004) Brain , vol.127 , pp. 420-430
    • Bandopadhyay, R.1    Kingsbury, A.E.2    Cookson, M.R.3
  • 6
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD3MXkt1Kitbo%3D, PID: 11403877
    • Blum D, Torch S, Lambeng N et al (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson’s disease. Prog Neurobiol 65(2):135–172
    • (2001) Prog Neurobiol , vol.65 , Issue.2 , pp. 135-172
    • Blum, D.1    Torch, S.2    Lambeng, N.3
  • 7
    • 84870388647 scopus 로고    scopus 로고
    • Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner
    • COI: 1:CAS:528:DC%2BC38Xhsl2jtbrL
    • Bourke CH, Raees MQ, Malviya S et al (2013) Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner. Psychoneuroendocrino 38:84–93
    • (2013) Psychoneuroendocrino , vol.38 , pp. 84-93
    • Bourke, C.H.1    Raees, M.Q.2    Malviya, S.3
  • 8
    • 84863856215 scopus 로고    scopus 로고
    • EPAS1 and EGLN1 associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai–Tibetan Plateau
    • COI: 1:CAS:528:DC%2BC38XntFahsrs%3D
    • Buroker NE, Ning XH, Zhou ZN et al (2012) EPAS1 and EGLN1 associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai–Tibetan Plateau. Blood Cell Mol Dis 49:67–73
    • (2012) Blood Cell Mol Dis , vol.49 , pp. 67-73
    • Buroker, N.E.1    Ning, X.H.2    Zhou, Z.N.3
  • 9
    • 79954520907 scopus 로고    scopus 로고
    • Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
    • COI: 1:CAS:528:DC%2BC3MXksFSku7Y%3D, PID: 21296869
    • Chan NC, Salazar AM, Pham AH et al (2011) Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 20(9):1726–1737
    • (2011) Hum Mol Genet , vol.20 , Issue.9 , pp. 1726-1737
    • Chan, N.C.1    Salazar, A.M.2    Pham, A.H.3
  • 10
    • 33646578517 scopus 로고    scopus 로고
    • Quercetin inhibition of ROS-dependent and independent apoptosis in rat glioma C6 cells
    • COI: 1:CAS:528:DC%2BD28XkvVyntr4%3D, PID: 16647178
    • Chen TJ, Jeng JY, Lin CW et al (2006) Quercetin inhibition of ROS-dependent and independent apoptosis in rat glioma C6 cells. Toxicology 223:113–126
    • (2006) Toxicology , vol.223 , pp. 113-126
    • Chen, T.J.1    Jeng, J.Y.2    Lin, C.W.3
  • 11
    • 84862816740 scopus 로고    scopus 로고
    • The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint
    • COI: 1:CAS:528:DC%2BC38Xjt1yhur8%3D, PID: 22200450
    • Chen Y, Fang ST, Yeh PC et al (2012) The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint. Biochim Biophys Acta 1822:573–580
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 573-580
    • Chen, Y.1    Fang, S.T.2    Yeh, P.C.3
  • 12
    • 14644435166 scopus 로고    scopus 로고
    • Dopaminergic neurons
    • COI: 1:CAS:528:DC%2BD2MXhvVGjs7s%3D, PID: 15743669
    • Chinta SJ, Andersen JK (2005) Dopaminergic neurons. Int J Biochem Cell Biol 37(5):942–946
    • (2005) Int J Biochem Cell Biol , vol.37 , Issue.5 , pp. 942-946
    • Chinta, S.J.1    Andersen, J.K.2
  • 13
    • 0036254579 scopus 로고    scopus 로고
    • Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury
    • COI: 1:CAS:528:DC%2BD38Xjs1Gksbk%3D, PID: 12011585
    • Chong ZZ, Lin SH, Maiese K (2002) Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury. J Vasc Res 39(2):131–147
    • (2002) J Vasc Res , vol.39 , Issue.2 , pp. 131-147
    • Chong, Z.Z.1    Lin, S.H.2    Maiese, K.3
  • 14
    • 45049085458 scopus 로고    scopus 로고
    • Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation
    • COI: 1:CAS:528:DC%2BD1cXnsF2lt7Y%3D, PID: 18502140
    • Chou AH, Yeh TH, Ouyang P et al (2008) Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation. Neurobiol Dis 31:89–101
    • (2008) Neurobiol Dis , vol.31 , pp. 89-101
    • Chou, A.H.1    Yeh, T.H.2    Ouyang, P.3
  • 15
    • 0026776269 scopus 로고
    • Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity
    • COI: 1:CAS:528:DyaK38Xks1Gns7o%3D, PID: 1352289
    • Daubner SC, Lauriano C, Haycock JW et al (1992) Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity. J Biol Chem 267:12639–12646
    • (1992) J Biol Chem , vol.267 , pp. 12639-12646
    • Daubner, S.C.1    Lauriano, C.2    Haycock, J.W.3
  • 16
    • 77949272190 scopus 로고    scopus 로고
    • UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein
    • COI: 1:CAS:528:DC%2BC3cXjtFyhsLw%3D, PID: 19879917
    • Day INM, Thompson RJ (2010) UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein. Prog Neurobiol 90:327–362
    • (2010) Prog Neurobiol , vol.90 , pp. 327-362
    • Day, I.N.M.1    Thompson, R.J.2
  • 17
    • 77955980575 scopus 로고    scopus 로고
    • An approach based on Density Functional Theory (DFT) calculations to assess the Candida antarctica lipase B selectivity in rutin, isoquercitrin and quercetin acetylation
    • De Oliveira EB, Humeau C, Maia ER et al (2010) An approach based on Density Functional Theory (DFT) calculations to assess the Candida antarctica lipase B selectivity in rutin, isoquercitrin and quercetin acetylation. J Mol Catal B Enzym 66(30):325–331
    • (2010) J Mol Catal B Enzym , vol.66 , Issue.30 , pp. 325-331
    • De Oliveira, E.B.1    Humeau, C.2    Maia, E.R.3
  • 18
    • 37549011856 scopus 로고    scopus 로고
    • Mutation analysis of the parkin and PINK1 genes in American Caucasian early-onset Parkinson disease families
    • COI: 1:CAS:528:DC%2BD1cXivFSrsw%3D%3D, PID: 18068301
    • Deng H, Le W, Shahed J et al (2008) Mutation analysis of the parkin and PINK1 genes in American Caucasian early-onset Parkinson disease families. Neurosci Lett 430:18–22
    • (2008) Neurosci Lett , vol.430 , pp. 18-22
    • Deng, H.1    Le, W.2    Shahed, J.3
  • 19
    • 84862128438 scopus 로고    scopus 로고
    • TDP-43 aggregation in neurodegeneration: are stress granules the key?
    • COI: 1:CAS:528:DC%2BC38Xot1ynurc%3D, PID: 22405725
    • Dewey CM, Cenik B, Sephton CF et al (2012) TDP-43 aggregation in neurodegeneration: are stress granules the key? Brain Res 1462:16–25
    • (2012) Brain Res , vol.1462 , pp. 16-25
    • Dewey, C.M.1    Cenik, B.2    Sephton, C.F.3
  • 20
    • 0033593612 scopus 로고    scopus 로고
    • Caspase-3-like proteases and 6-hydroxydopamine induced neuronal cell death
    • COI: 1:CAS:528:DyaK1MXhslalsg%3D%3D, PID: 9889353
    • Dodel RC, Du Y, Bales KR et al (1999) Caspase-3-like proteases and 6-hydroxydopamine induced neuronal cell death. Brain Res Mol Brain Res 64:141–148
    • (1999) Brain Res Mol Brain Res , vol.64 , pp. 141-148
    • Dodel, R.C.1    Du, Y.2    Bales, K.R.3
  • 21
    • 84858690615 scopus 로고    scopus 로고
    • Neuronal vulnerability in Parkinson’s disease
    • Double KL (2012) Neuronal vulnerability in Parkinson’s disease. Parkinsonism Relat D 18S1:S52–S54
    • (2012) Parkinsonism Relat D , vol.18S1 , pp. S52-S54
    • Double, K.L.1
  • 22
    • 60749104683 scopus 로고    scopus 로고
    • The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
    • COI: 1:CAS:528:DC%2BD1MXhvFKjtLo%3D, PID: 19221555
    • Franchi L, Eigenbrod T, Muñoz-Planillo R et al (2009) The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol 10(3):241–247
    • (2009) Nat Immunol , vol.10 , Issue.3 , pp. 241-247
    • Franchi, L.1    Eigenbrod, T.2    Muñoz-Planillo, R.3
  • 23
    • 43149115834 scopus 로고    scopus 로고
    • 6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells
    • COI: 1:CAS:528:DC%2BD1cXlslOqsr0%3D, PID: 18395527
    • Gomez-Lazaro M, Bonekamp NA, Galindo MF et al (2008) 6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells. Free Radic Biol Med 44:1960–1969
    • (2008) Free Radic Biol Med , vol.44 , pp. 1960-1969
    • Gomez-Lazaro, M.1    Bonekamp, N.A.2    Galindo, M.F.3
  • 24
    • 33745713436 scopus 로고    scopus 로고
    • OPA1 and PARL keep a lid on apoptosis
    • COI: 1:CAS:528:DC%2BD28Xns1Cgtr0%3D, PID: 16839872
    • Gottlieb E (2006) OPA1 and PARL keep a lid on apoptosis. Cell 126(1):27–29
    • (2006) Cell , vol.126 , Issue.1 , pp. 27-29
    • Gottlieb, E.1
  • 25
    • 84872332646 scopus 로고    scopus 로고
    • N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress
    • Graya JJ, Zommera AE, Bouchard RJ et al (2013) N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress. Brain Res 1494:28–43
    • (2013) Brain Res , vol.1494 , pp. 28-43
    • Graya, J.J.1    Zommera, A.E.2    Bouchard, R.J.3
  • 26
    • 84879708226 scopus 로고    scopus 로고
    • Distinct functional brain regional integration of Casp3, Ascl1 and S100a6 gene expression in spatial memory
    • COI: 1:CAS:528:DC%2BC3sXht1Gjs7%2FO, PID: 23792135
    • Gruden MA, Storozheva ZI, Sewell RDE et al (2013) Distinct functional brain regional integration of Casp3, Ascl1 and S100a6 gene expression in spatial memory. Behav Brain Res 252:230–238
    • (2013) Behav Brain Res , vol.252 , pp. 230-238
    • Gruden, M.A.1    Storozheva, Z.I.2    Sewell, R.D.E.3
  • 27
    • 0034680913 scopus 로고    scopus 로고
    • Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
    • COI: 1:CAS:528:DC%2BD3cXosVSksLo%3D, PID: 10973942
    • Imai Y, Soda M, Takahashi R (2000) Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 275:35661–35664
    • (2000) J Biol Chem , vol.275 , pp. 35661-35664
    • Imai, Y.1    Soda, M.2    Takahashi, R.3
  • 28
    • 0035900793 scopus 로고    scopus 로고
    • CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation
    • COI: 1:CAS:528:DC%2BD3MXptlelsL4%3D, PID: 11557750
    • Jiang J, Ballinger CA, Wu Y et al (2001) CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation. J Biol Chem 276(46):42938–42944
    • (2001) J Biol Chem , vol.276 , Issue.46 , pp. 42938-42944
    • Jiang, J.1    Ballinger, C.A.2    Wu, Y.3
  • 29
    • 77956183278 scopus 로고    scopus 로고
    • Mechanisms of L-DOPA-induced cytotoxicity in rat adrenal pheochromocytoma cells: implication of oxidative stress-related kinases and cyclic AMP
    • COI: 1:CAS:528:DC%2BC3cXhtFams73F
    • Jin CM, Yang YJ, Huang HS et al (2010) Mechanisms of L-DOPA-induced cytotoxicity in rat adrenal pheochromocytoma cells: implication of oxidative stress-related kinases and cyclic AMP. Neurosc 170:390–398
    • (2010) Neurosc , vol.170 , pp. 390-398
    • Jin, C.M.1    Yang, Y.J.2    Huang, H.S.3
  • 30
    • 77958086270 scopus 로고    scopus 로고
    • Isoquercitrin is the most effective antioxidant in the plant Thuja orientalis and able to counteract oxidative-induced damage to a transformed cell line (RGC-5cells)
    • COI: 1:CAS:528:DC%2BC3cXhtlentr%2FL, PID: 20708054
    • Jung SH, Kim BJ, Lee EH et al (2010) Isoquercitrin is the most effective antioxidant in the plant Thuja orientalis and able to counteract oxidative-induced damage to a transformed cell line (RGC-5cells). Neurochem Int 57:713–721
    • (2010) Neurochem Int , vol.57 , pp. 713-721
    • Jung, S.H.1    Kim, B.J.2    Lee, E.H.3
  • 31
    • 70350002152 scopus 로고    scopus 로고
    • DJ-1 and prevention of oxidative stress in Parkinson’s disease and other age-related disorders
    • COI: 1:CAS:528:DC%2BD1MXhtlWgtL7E, PID: 19686841
    • Kahle PJ, Waak J, Gasser T (2009) DJ-1 and prevention of oxidative stress in Parkinson’s disease and other age-related disorders. Free Radic Biol Med 47:1354–1361
    • (2009) Free Radic Biol Med , vol.47 , pp. 1354-1361
    • Kahle, P.J.1    Waak, J.2    Gasser, T.3
  • 32
    • 75749134143 scopus 로고    scopus 로고
    • Low frequency of the PARK2 gene mutations in Polish patients with the early-onset form of Parkinson disease
    • PID: 19628420
    • Koziorowski D, Hoffman-Zacharska D, Sławek J et al (2010) Low frequency of the PARK2 gene mutations in Polish patients with the early-onset form of Parkinson disease. Parkinsonism Relat Disord 16:136–138
    • (2010) Parkinsonism Relat Disord , vol.16 , pp. 136-138
    • Koziorowski, D.1    Hoffman-Zacharska, D.2    Sławek, J.3
  • 33
    • 11844279094 scopus 로고    scopus 로고
    • Dietary rutin, but not its aglycone quercetin, ameliorates dextran sulfate sodium-induced experimental colitis in mice: attenuation of pro-inflammatory gene expression
    • COI: 1:CAS:528:DC%2BD2MXivVSgsQ%3D%3D, PID: 15652231
    • Kwon KH, Murakami A, Tanaka T et al (2005) Dietary rutin, but not its aglycone quercetin, ameliorates dextran sulfate sodium-induced experimental colitis in mice: attenuation of pro-inflammatory gene expression. Biochem Pharmacol 69:395–406
    • (2005) Biochem Pharmacol , vol.69 , pp. 395-406
    • Kwon, K.H.1    Murakami, A.2    Tanaka, T.3
  • 34
    • 70549098228 scopus 로고    scopus 로고
    • Caspase-7: a protease involved in apoptosis and inflammation
    • COI: 1:CAS:528:DC%2BD1MXhsV2mt7zJ, PID: 19782763
    • Lamkanfi M, Kanneganti TD (2010) Caspase-7: a protease involved in apoptosis and inflammation. Int J Biochem Cell Biol 42:21–24
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 21-24
    • Lamkanfi, M.1    Kanneganti, T.D.2
  • 35
    • 77956027401 scopus 로고    scopus 로고
    • Effect of neuroprotective flavonoids of Agrimonia eupatoria on glutamate-induced oxidative injury to HT22 hippocampal cells
    • COI: 1:CAS:528:DC%2BC3cXhtlCktLzN, PID: 20699556
    • Lee KY, Hwang L, Jeong EJ et al (2010) Effect of neuroprotective flavonoids of Agrimonia eupatoria on glutamate-induced oxidative injury to HT22 hippocampal cells. Biosci Biotechnol Biochem 74(8):1704–1706
    • (2010) Biosci Biotechnol Biochem , vol.74 , Issue.8 , pp. 1704-1706
    • Lee, K.Y.1    Hwang, L.2    Jeong, E.J.3
  • 36
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BD28XhtVyktbbO, PID: 17051205
    • Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443:787–795
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 37
    • 83255165438 scopus 로고    scopus 로고
    • Gene expression pathway analysis, q-RT-PCR and immunoblotting reveal early effects associated with hippocampal damage and gliosis
    • COI: 1:CAS:528:DC%2BC38XhsFShsrs%3D, PID: 22108043
    • Little AR, Miller DB, Li S et al (2012) Gene expression pathway analysis, q-RT-PCR and immunoblotting reveal early effects associated with hippocampal damage and gliosis. Neurotoxicol Teratol 34:72–82
    • (2012) Neurotoxicol Teratol , vol.34 , pp. 72-82
    • Little, A.R.1    Miller, D.B.2    Li, S.3
  • 38
    • 4644320312 scopus 로고    scopus 로고
    • Alterations of N-ethylmaleimide-sensitive atpase following transient cerebral ischemia
    • COI: 1:CAS:528:DC%2BD2cXotF2gsrs%3D
    • Liu C, Hu B (2004) Alterations of N-ethylmaleimide-sensitive atpase following transient cerebral ischemia. Neurosc 128:767–774
    • (2004) Neurosc , vol.128 , pp. 767-774
    • Liu, C.1    Hu, B.2
  • 39
    • 84878240917 scopus 로고    scopus 로고
    • Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity
    • COI: 1:CAS:528:DC%2BC3sXht1yhtLvK, PID: 23670213
    • Magalingam KB, Radhakrishnan A, Haleagrahara N (2013) Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity. Int J Mol Med 32:235–240
    • (2013) Int J Mol Med , vol.32 , pp. 235-240
    • Magalingam, K.B.1    Radhakrishnan, A.2    Haleagrahara, N.3
  • 40
    • 84892573315 scopus 로고    scopus 로고
    • Protective effects of flavonol isoquercitrin, against 6-hydroxydopamine (6-OHDA)-induced toxicity PC12 cells
    • PID: 24443837
    • Magalingam KB, Radhakrishnan A, Haleagrahara N (2014) Protective effects of flavonol isoquercitrin, against 6-hydroxydopamine (6-OHDA)-induced toxicity PC12 cells. BMC Res Notes 7:49
    • (2014) BMC Res Notes , vol.7 , pp. 49
    • Magalingam, K.B.1    Radhakrishnan, A.2    Haleagrahara, N.3
  • 41
    • 59149099105 scopus 로고    scopus 로고
    • Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy
    • COI: 1:CAS:528:DC%2BD1MXhs1eisL8%3D, PID: 19094991
    • Matas J, Young NT, Bourcier-Lucas C et al (2009) Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy. J Mol Cell Cardiol 46(3):420–430
    • (2009) J Mol Cell Cardiol , vol.46 , Issue.3 , pp. 420-430
    • Matas, J.1    Young, N.T.2    Bourcier-Lucas, C.3
  • 42
    • 65649106909 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD1MXktFCqsLw%3D, PID: 23105815
    • Nikam S, Nikam P, Ahaley SK et al (2009) Oxidative stress in Parkinson’s disease. Indian J Clin Biochem 24:98–101
    • (2009) Indian J Clin Biochem , vol.24 , pp. 98-101
    • Nikam, S.1    Nikam, P.2    Ahaley, S.K.3
  • 43
    • 34247229733 scopus 로고    scopus 로고
    • Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules
    • COI: 1:CAS:528:DC%2BD2sXktVSmtLc%3D, PID: 17392519
    • Nonhoff U, Ralser M, Welzel F et al (2007) Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules. Mol Biol Cell 18(4):1385–1396
    • (2007) Mol Biol Cell , vol.18 , Issue.4 , pp. 1385-1396
    • Nonhoff, U.1    Ralser, M.2    Welzel, F.3
  • 44
    • 0034610328 scopus 로고    scopus 로고
    • Caspase-1 and −3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis
    • COI: 1:CAS:528:DC%2BD3cXoslynsbs%3D, PID: 11095709
    • Pasinelli P, Houseweart MK, Brown RH Jr et al (2000) Caspase-1 and −3 are sequentially activated in motor neuron death in Cu, Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 97(25):13901–13906
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.25 , pp. 13901-13906
    • Pasinelli, P.1    Houseweart, M.K.2    Brown, R.H.3
  • 45
    • 33745818640 scopus 로고    scopus 로고
    • ROS-triggered caspase 2 activation and feedback amplification loop in β-carotene-induced apoptosis
    • COI: 1:CAS:528:DC%2BD28XntFWru7s%3D, PID: 16843824
    • Prasad V, Chandele A, Jagtap JC et al (2006) ROS-triggered caspase 2 activation and feedback amplification loop in β-carotene-induced apoptosis. Free Radic Biol Med 41:431–442
    • (2006) Free Radic Biol Med , vol.41 , pp. 431-442
    • Prasad, V.1    Chandele, A.2    Jagtap, J.C.3
  • 46
    • 12344317072 scopus 로고    scopus 로고
    • An integrative approach to gain insights into the cellular function of human ataxin-2
    • COI: 1:CAS:528:DC%2BD2MXkvFOrug%3D%3D, PID: 15663938
    • Ralser M, Albrecht M, Nonhoff U et al (2005) An integrative approach to gain insights into the cellular function of human ataxin-2. J Mol Biol 346(1):203–214
    • (2005) J Mol Biol , vol.346 , Issue.1 , pp. 203-214
    • Ralser, M.1    Albrecht, M.2    Nonhoff, U.3
  • 47
    • 84877736033 scopus 로고    scopus 로고
    • Evidence of oxidative stress in young and aged DJ-1-deficient mice
    • COI: 1:CAS:528:DC%2BC3sXmsFequ70%3D, PID: 23587484
    • Raman AV, Chou VP, Duyanen JA et al (2013) Evidence of oxidative stress in young and aged DJ-1-deficient mice. FEBS Lett 587:1562–1570
    • (2013) FEBS Lett , vol.587 , pp. 1562-1570
    • Raman, A.V.1    Chou, V.P.2    Duyanen, J.A.3
  • 48
    • 79952634367 scopus 로고    scopus 로고
    • The distribution of neuron-specific gene family member 1 in brain and germ cells: implications for the regulation of germ-line development by brain
    • COI: 1:CAS:528:DC%2BC3MXlslektbk%3D, PID: 21404368
    • Rengaraj D, Lee BR, Park KJ et al (2011) The distribution of neuron-specific gene family member 1 in brain and germ cells: implications for the regulation of germ-line development by brain. Dev Dyn 240:850–861
    • (2011) Dev Dyn , vol.240 , pp. 850-861
    • Rengaraj, D.1    Lee, B.R.2    Park, K.J.3
  • 49
    • 0034114604 scopus 로고    scopus 로고
    • Neuroprotection by the inhibition of apoptosis
    • COI: 1:CAS:528:DC%2BD3cXivVyhurk%3D, PID: 10764048
    • Robertson GS, Crocker SJ, Nicholson DW et al (2000) Neuroprotection by the inhibition of apoptosis. Brain Pathol 10(2):283–292
    • (2000) Brain Pathol , vol.10 , Issue.2 , pp. 283-292
    • Robertson, G.S.1    Crocker, S.J.2    Nicholson, D.W.3
  • 50
    • 3142514201 scopus 로고    scopus 로고
    • Protein aggregation and neurodegenerative disease
    • PID: 15272267
    • Ross CA, Poirier MA (2004) Protein aggregation and neurodegenerative disease. Nat Med 10:S10–S17
    • (2004) Nat Med , vol.10 , pp. S10-S17
    • Ross, C.A.1    Poirier, M.A.2
  • 51
    • 0036845661 scopus 로고    scopus 로고
    • High glucose-induced oxidative stress and mitochondrial dysfunction in neurons
    • COI: 1:CAS:528:DC%2BD38XovVCiur0%3D, PID: 12409316
    • Russell JW, Golovoy D, Vincent AM et al (2002) High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J 16(13):1738–1748
    • (2002) FASEB J , vol.16 , Issue.13 , pp. 1738-1748
    • Russell, J.W.1    Golovoy, D.2    Vincent, A.M.3
  • 52
    • 84864684399 scopus 로고    scopus 로고
    • The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock
    • PID: 22579715
    • Sanjuán Szklarz LK, Scorrano L (2012) The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock. Biochim Biophys Acta 1817:1886–1893
    • (2012) Biochim Biophys Acta , vol.1817 , pp. 1886-1893
    • Sanjuán Szklarz, L.K.1    Scorrano, L.2
  • 53
    • 34547803698 scopus 로고    scopus 로고
    • Antioxidant and prooxidant effects of quercetin on lyceraldehyde-3-phosphate dehydrogenase
    • COI: 1:CAS:528:DC%2BD2sXovFyht70%3D, PID: 17559999
    • Schmalhausen EV, Zhlobek EB, Shalova IN et al (2007) Antioxidant and prooxidant effects of quercetin on lyceraldehyde-3-phosphate dehydrogenase. Food Chem Toxicol 45:1988–1993
    • (2007) Food Chem Toxicol , vol.45 , pp. 1988-1993
    • Schmalhausen, E.V.1    Zhlobek, E.B.2    Shalova, I.N.3
  • 54
    • 0028960151 scopus 로고
    • Alterations in tyrosine hydroxylase expression following partial lesions of the nigrostriatal bundle
    • COI: 1:CAS:528:DyaK2MXktFCit78%3D, PID: 7609616
    • Sherman TG, Moody CA (1995) Alterations in tyrosine hydroxylase expression following partial lesions of the nigrostriatal bundle. Brain Res Mol Brain Res 29(2):285–296
    • (1995) Brain Res Mol Brain Res , vol.29 , Issue.2 , pp. 285-296
    • Sherman, T.G.1    Moody, C.A.2
  • 55
    • 67349146392 scopus 로고    scopus 로고
    • In vitro and in vivo determination of antioxidant activity and mode of action of isoquercitrin and Hyptis fasciculata
    • COI: 1:CAS:528:DC%2BD1MXptVKrtbg%3D, PID: 19200698
    • Silva CG, Raulino RJ, Cerqueira DM et al (2009) In vitro and in vivo determination of antioxidant activity and mode of action of isoquercitrin and Hyptis fasciculata. Phytomedicine 16:761–767
    • (2009) Phytomedicine , vol.16 , pp. 761-767
    • Silva, C.G.1    Raulino, R.J.2    Cerqueira, D.M.3
  • 56
    • 30344475717 scopus 로고    scopus 로고
    • Free radicals and oxidative stress in neurodegenerative diseases: relevance of dietary antioxidants
    • Singh RP, Sharad S, Kapur S (2004) Free radicals and oxidative stress in neurodegenerative diseases: relevance of dietary antioxidants. J Indian Acad Clin Med 5(3):218–225
    • (2004) J Indian Acad Clin Med , vol.5 , Issue.3 , pp. 218-225
    • Singh, R.P.1    Sharad, S.2    Kapur, S.3
  • 57
    • 0027517462 scopus 로고
    • A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
    • PID: 8221884
    • Söllner T, Bennett MK, Whiteheart SW et al (1993) A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell 75(3):409–418
    • (1993) Cell , vol.75 , Issue.3 , pp. 409-418
    • Söllner, T.1    Bennett, M.K.2    Whiteheart, S.W.3
  • 58
    • 84864684399 scopus 로고    scopus 로고
    • The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock
    • Szlarz LKS, Scorrano L (2012) The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock. Biochim et Biophys Acta 1817:1886–1893
    • (2012) Biochim et Biophys Acta , vol.1817 , pp. 1886-1893
    • Szlarz, L.K.S.1    Scorrano, L.2
  • 59
    • 0036591852 scopus 로고    scopus 로고
    • Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease
    • Tabner BJ, Turnbull S, El-Agnaf OM et al (2002) Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease. Free Radic Biol Med 11:1076–1083
    • (2002) Free Radic Biol Med , vol.11 , pp. 1076-1083
    • Tabner, B.J.1    Turnbull, S.2    El-Agnaf, O.M.3
  • 60
    • 0034093161 scopus 로고    scopus 로고
    • Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG trinucleotide repeat expansion in patients with hereditary spinocerebellar ataxia from Chinese kindreds
    • COI: 1:STN:280:DC%2BD3c3ivFWitA%3D%3D, PID: 10768629
    • Tang B, Liu C, Shen L et al (2000) Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG trinucleotide repeat expansion in patients with hereditary spinocerebellar ataxia from Chinese kindreds. Arch Neurol 57(4):540–544
    • (2000) Arch Neurol , vol.57 , Issue.4 , pp. 540-544
    • Tang, B.1    Liu, C.2    Shen, L.3
  • 61
    • 0034533082 scopus 로고    scopus 로고
    • Reactive oxygen species in cell signaling
    • COI: 1:CAS:528:DC%2BD3cXptFSksbg%3D, PID: 11076791
    • Thannickal VJ, Fanburg BL (2000) Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 279:L1005–L1028
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279 , pp. L1005-L1028
    • Thannickal, V.J.1    Fanburg, B.L.2
  • 62
    • 57449116963 scopus 로고    scopus 로고
    • Ataxin-2 associates with rough endoplasmic reticulum
    • Van de Loo S, Eich F, Nonis D et al (2009) Ataxin-2 associates with rough endoplasmic reticulum. J Exp Neurol 215:110–118
    • (2009) J Exp Neurol , vol.215 , pp. 110-118
    • Van de Loo, S.1    Eich, F.2    Nonis, D.3
  • 63
    • 84984550472 scopus 로고    scopus 로고
    • Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro
    • COI: 1:CAS:528:DC%2BD28XotlWksbg%3D, PID: 16828712
    • Wagner C, Fachinetto R, Dalla Corte CL et al (2006) Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro. Brain Res 1107:192–198
    • (2006) Brain Res , vol.1107 , pp. 192-198
    • Wagner, C.1    Fachinetto, R.2    Dalla Corte, C.L.3
  • 64
    • 0028127058 scopus 로고
    • Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis
    • COI: 1:CAS:528:DyaK2MXisFynsrk%3D, PID: 7535401
    • Walkinshaw G, Waters CM (1994) Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis. Neuroscience 63(4):975–998
    • (1994) Neuroscience , vol.63 , Issue.4 , pp. 975-998
    • Walkinshaw, G.1    Waters, C.M.2
  • 65
    • 0035003581 scopus 로고    scopus 로고
    • N-ethylmaleimide sensitive factor (NSF) structure and function
    • COI: 1:CAS:528:DC%2BD3MXktlCmsrw%3D, PID: 11352269
    • Whiteheart SW, Schraw T, Matveeva EA (2001) N-ethylmaleimide sensitive factor (NSF) structure and function. Int Rev Cytol 207:71–112
    • (2001) Int Rev Cytol , vol.207 , pp. 71-112
    • Whiteheart, S.W.1    Schraw, T.2    Matveeva, E.A.3
  • 66
    • 0035957767 scopus 로고    scopus 로고
    • Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells
    • COI: 1:CAS:528:DC%2BD3MXislGktL8%3D, PID: 11311863
    • Xu R, Liu J, Chen X et al (2001) Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells. Brain Res 899:10–19
    • (2001) Brain Res , vol.899 , pp. 10-19
    • Xu, R.1    Liu, J.2    Chen, X.3
  • 67
    • 40649109304 scopus 로고    scopus 로고
    • In vitro antioxidant properties of rutin
    • COI: 1:CAS:528:DC%2BD1cXjtlyksr4%3D
    • Yang J, Guoa J, Yuan J (2008) In vitro antioxidant properties of rutin. LWT 41:1060–1066
    • (2008) LWT , vol.41 , pp. 1060-1066
    • Yang, J.1    Guoa, J.2    Yuan, J.3
  • 68
    • 40849116519 scopus 로고    scopus 로고
    • The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM
    • COI: 1:CAS:528:DC%2BD1cXis12iurc%3D, PID: 18299352
    • Yap CC, Wisco D, Kujala P et al (2008) The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM. J Cell Biol 180:827–842
    • (2008) J Cell Biol , vol.180 , pp. 827-842
    • Yap, C.C.1    Wisco, D.2    Kujala, P.3
  • 69
    • 79955480131 scopus 로고    scopus 로고
    • Activity-dependent interactions of NSF and SNAP at living synapses
    • COI: 1:CAS:528:DC%2BC3MXlsFamsbs%3D
    • Yu W, Kawasaki F, Ordway RW (2011) Activity-dependent interactions of NSF and SNAP at living synapses. Mol Cell Neurosc 47:19–27
    • (2011) Mol Cell Neurosc , vol.47 , pp. 19-27
    • Yu, W.1    Kawasaki, F.2    Ordway, R.W.3
  • 70
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
    • COI: 1:CAS:528:DC%2BD3cXosVOjs7o%3D, PID: 11078524
    • Zhang Y, Gao J, Chung KK et al (2000) Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc Natl Acad Sci U S A 97(24):13354–13359
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.24 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3
  • 71
    • 33747891213 scopus 로고    scopus 로고
    • Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates
    • COI: 1:CAS:528:DC%2BD28Xotlais70%3D, PID: 16822850
    • Zhong X, Pittman RN (2006) Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates. Hum Mol Genet 15(16):2409–2420
    • (2006) Hum Mol Genet , vol.15 , Issue.16 , pp. 2409-2420
    • Zhong, X.1    Pittman, R.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.