Trimethyltin-induced neurotoxicity: Gene expression pathway analysis, q-RT-PCR and immunoblotting reveal early effects associated with hippocampal damage and gliosis

Neurotoxicology and Teratology

Volumn 34, Issue 1, 2012, Pages 72-82

  Little, A R ^a   Miller, D B ^a   Li, S ^a   Kashon, M L ^a   O'Callaghan, J P ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Microarray; Neurodegeneration; Neuroinflammation; Neurotoxicity; Trimethyltin; Ubiquitin proteosome

Indexed keywords

MESSENGER RNA; TRIMETHYLTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; CELL ACTIVATION; CELL STRESS; CEREBELLUM CORTEX; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; ENERGY METABOLISM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GLIA CELL; GLIOSIS; HIPPOCAMPUS; IMMUNOBLOTTING; LONG TERM EXPOSURE; MALE; MOLECULAR DYNAMICS; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE;

ANIMALS; CHRONIC DISEASE; EARLY DIAGNOSIS; FEMALE; GENE EXPRESSION PROFILING; GLIOSIS; HIPPOCAMPUS; IMMUNOBLOTTING; MALE; NEURODEGENERATIVE DISEASES; NEUROTOXINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, LONG-EVANS; REAL-TIME POLYMERASE CHAIN REACTION; TIME FACTORS; TRIMETHYLTIN COMPOUNDS;

RATTUS;

EID: 83255165438     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2011.09.012     Document Type: Article

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