Vitamin D defciency and hashimoto’s thyroiditis in children and adolescents: A critical vitamin D level for this association?

JCRPE Journal of Clinical Research in Pediatric Endocrinology

Volumn 7, Issue 2, 2015, Pages 128-133

  Evliyaoğlu, Olcay ^a   Acar, Manolya ^a   Özcabı, Bahar ^a   Erginöz, Ethem ^a   Bucak, Feride ^a   Ercan, Oya ^a   Kucur, Mine ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Adolescents; Children; Deficiency; Hashimoto thyroiditis; Vitamin D

Indexed keywords

CALCIFEDIOL; LIOTHYRONINE; THYROID PEROXIDASE; THYROTROPIN; THYROXINE; VITAMIN D;

ADOLESCENT; ARTICLE; CASE CONTROL STUDY; CHEMOLUMINESCENCE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; EUTHYROIDISM; FEMALE; HASHIMOTO DISEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; MALE; PREVALENCE; SUBCLINICAL HYPOTHYROIDISM; SUN EXPOSURE; THYROID FUNCTION TEST; VITAMIN D DEFICIENCY; BLOOD; COMPLICATION; PRESCHOOL CHILD; VITAMIN B DEFICIENCY;

ADOLESCENT; CALCIFEDIOL; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; HASHIMOTO DISEASE; HUMANS; MALE; PREVALENCE; THYROID FUNCTION TESTS; VITAMIN B DEFICIENCY; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84930432645     PISSN: 13085727     EISSN: 13085735     Source Type: Journal    
DOI: 10.4274/jcrpe.2011     Document Type: Article

References (44)

1. Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M; Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society. Vitamin D deficiency in children and its management: Review of current knowledge and recommendations. Pediatrics 2008;122:398-417.
2. Holick M F. Resurrection of vitamin D deficiency and rickets. J Clin Invest 2006;116:2062-2072.
3. Holick M F. Vitamin D deficiency. N Engl J Med 2007;357:266-281.
4. DeLuca H F. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr 2004;80(Suppl 6):1689-1696.
5. Deluca H F, Cantorna MT. Vitamin D: Its role and uses in immunology. FASEB J 2001;15:2579-2585.
6. Mathieu C, Adorini L. The coming of age of 1.25-dihydroxyvitamin D(3) analogs as immunomodulatory agents. Trends Mol Med 2002;8:174-179.
7. Schauber J, Dorschner RA, Coda AB, Büchau AS, Liu P T, Kiken D, Helfrich YR, Kang S, Elalieh HZ, Steinmeyer A, Zügel U, Bikle D D, Modlin RL, Gallo RL. Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. J Clin Invest 2007;117:803-811. Epub 2007 Feb 8
8. Wang T T, Nestel F P, Bourdeau V, Nagai Y, Wang Q, Liao J, Tavera-Mendoza L, Lin R, Hanrahan JW, Mader S, White JH. Cutting edge: 1.25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 2004;173:2909-2912.
9. Gombart A F, Borregaard N, Koeffler H P. Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1.25-dihydroxyvitamin D3. FASEB J 2005;19:1067-1077.
10. Koizumi T, Nakao Y, Matsui T, Nakagawa T, Matsuda S, Komoriya K, Kanai Y, Fujita T. Effects of corticosteroid and 1,24R-dihydroxyvitamin D3 administration on lymphoproliferation and autoimmune disease in MRL/MP-lpr/ lpr mice. Int Arch Allergy Appl Immunol 1985;77:396-404.
11. Mattner F, Smiroldo S, Galbiati F, Muller M, Di Lucia P, Poliani PL, Martino G, Panina-Bordignon P, Adorini L. Inhibition of TH1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1.25-dihydroxyvitamin D(3). Eur J Immunol 2000;30:498-508.
12. Lemire JM, Archer DC. 1.25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis. J Clin Invest 1991;87:1103-1107.
13. Cantorna M T, Hayes CE, DeLuca H F. 1.25-dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci U S A 1996;93:7861-7864.
14. Larsson P, Mattsson L, Klareskog L, Johnsson C. A vitamin D analogue (mc 1288) has immunomodulatory properties and suppresses collagen-induced arthritis (cia) without causing hypercalcaemia. Clin Exp Immunol 1998;114:277-283.
15. Cantorna M T, Hayes CE, DeLuca H F. 1.25-dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr 1998;128:68-72.
16. Cantorna M T, Munsick C, Bemiss C, Mahon BD. 1.25-dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease. J Nutr 2000;130:2648-2652.
17. Mathieu C, Waer M, Casteels K, Laureys J, Bouillon R. Prevention of type 1 diabetes in nod mice by nonhypercalcemic doses of a new structural analog of 1.25-dihydroxyvitamin D3, kh1060. Endocrinology 1995;136:866-872.
18. Fournier C, Gepner P, Sadouk M, Charreire J. In vivo beneficial effects of cyclosporin A and 1.25-dihydroxyvitamin D3 on the induction of experimental autoimmune thyroiditis. Clin Immunol Immunopathol 1990;54:53-63.
19. Chen W, Lin H, Wang M. Immune intervention effects on the induction of experimental autoimmune thyroiditis. J Huazhong Univ Sci Technolog Med Sci 2002;22:343-345.
20. Camurdan OM, Döğer E, Bideci A, Celik N, Cinaz P. Vitamin D status in children with hashimoto thyroiditis. J Pediatr Endocrinol Metab 2012;25:467-470.
21. Holick M F, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney R P, Murad MH, Weaver CM; Endocrine Society. Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2011;96:1911-1930. Epub 2011 Jun 6
22. Tamer G, Arik S, Tamer I, Coksert D. Relative vitamin D insufficiency in hashimoto’s thyroiditis. Thyroid 2011;21:891-896. Epub 2011 Jul 13
23. Kivity S, Agmon-Levin N, Zisappl M, Shapira Y, Nagy E V, Dankó K, Szekanecz Z, Langevitz P, Shoenfeld Y. Vitamin D and autoimmune thyroid diseases. Cell Mol Immunol 2011;8:243-247. Epub 2011 Jan 31
24. Bozkurt NC, Karbek B, Ucan B, Sahin M, Cakal E, Ozbek M, Delibasi T. The association between severity of vitamin D deficiency and hashimoto’s thyroiditis. Endocr Pract 2013;19:479-484.
25. Choi YM, Kim WG, Kim T Y, Bae SJ, Kim HK, Jang EK, Jeon MJ, Han JM, Lee SH, Baek JH, Shong YK, Kim WB. Low levels of serum vitamin D3 are associated with autoimmune thyroid disease in pre-menopausal women. Thyroid 2014;24:655-661. Epub 2014 Jan 30
26. Effraimidis G, Badenhoop K, Tijssen JG, Wiersinga WM. Vitamin D deficiency is not associated with early stages of thyroid autoimmunity. Eur J Endocrinol 2012;167:43-48. Epub 2012 Apr 19
27. Goswami R, Marwaha RK, Gupta N, Tandon N, Sreenivas V, Tomar N, Ray D, Kanwar R, Agarwal R. Prevalence of vitamin D deficiency and its relationship with thyroid autoimmunity in asian indians: A community-based survey. Br J Nutr 2009;102:382-386. Epub 2009 Feb 10
28. Waterhouse JC, Perez TH, Albert PJ. Reversing bacteria-induced vitamin D receptor dysfunction is key to autoimmune disease. Ann N Y Acad Sci 2009;1173:757-765.
29. Marshall TG. Vitamin D discovery outpaces fda decision making. Bioessays 2008;30:173-182.
30. Wang T T, Tavera-Mendoza LE, Laperriere D, Libby E, MacLeod NB, Nagai Y, Bourdeau V, Konstorum A, Lallemant B, Zhang R, Mader S, White JH. Large-scale in silico and microarray-based identification of direct 1.25-dihydroxyvitamin D3 target genes. Mol Endocrinol 2005;19:2685-2695. Epub 2005 Jul 7
31. Liu P T, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa M T, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006;311:1770-1773. Epub 2006 Feb 23
32. Wen L, Wong FS. How can the innate immune system influence autoimmunity in type 1 diabetes and other autoimmune disorders? Crit Rev Immunol 2005;25:225-250.
33. Proal A D, Albert PJ, Marshall TG. Dysregulation of the vitamin D nuclear receptor may contribute to the higher prevalence of some autoimmune diseases in women. Ann N Y Acad Sci 2009;1173:252-259.
34. Yazici D, Yavuz D, Tarcin O, Sancak S, Deyneli O, Akalin S. Vitamin D receptor gene ApaI, TaqI, FokI and BsmI polymorphisms in a group of turkish patients with hashimoto’s thyroiditis. Minerva Endocrinol 2013;38:195-201.
35. Roy S, Shrinivas K, Bagchi B. A stochastic chemical dynamic approach to correlate autoimmunity and optimal vitamin-D range. PLoS One 2014;9:100635.
36. Ross AC, Manson JE, Abrams SA, Aloia J F, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne S T, Rosen CJ, Shapses SA. The 2011 dietary reference intakes for calcium and vitamin D: What dietetics practitioners need to know. J Am Diet Assoc 2011;111:524-527.
37. Wang TJ, Pencina MJ, Booth SL, Jacques P F, Ingelsson E, Lanier K, Benjamin EJ, D’Agostino RB, Wolf M, Vasan RS. Vitamin D deficiency and risk of cardiovascular disease. Circulation 2008;117:503-511. Epub 2008 Jan 7
38. Stolzenberg-Solomon RZ, Jacobs EJ, Arslan AA, Qi D, Patel AV, Helzlsouer KJ, Weinstein SJ, McCullough ML, Purdue MP, Shu XO, Snyder K, Virtamo J, Wilkins LR, Yu K, Zeleniuch-Jacquotte A, Zheng W, Albanes D, Cai Q, Harvey C, Hayes R, Clipp S, Horst RL, Irish L, Koenig K, Le Marchand L, Kolonel LN. Circulating 25-hydroxyvitamin D and risk of pancreatic cancer: Cohort consortium vitamin D pooling project of rarer cancers. Am J Epidemiol 2010;172:81-93. Epub 2010 Jun 18
39. Melamed ML, Michos ED, Post W, Astor B. 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 2008;168:1629-1637.
40. Toner C D, Davis C D, Milner JA. The vitamin D and cancer conundrum: Aiming at a moving target. J Am Diet Assoc 2010;110:1492-1500.
41. Visser M, Deeg DJ, Puts M T, Seidell JC, Lips P. Low serum concentrations of 25-hydroxyvitamin D in older persons and the risk of nursing home admission. Am J Clin Nutr 2006;84:616-622.
42. Berg J P, Liane KM, Bjørhovde SB, Bjøro T, Torjesen PA, Haug E. Vitamin D receptor binding and biological effects of cholecalciferol analogues in rat thyroid cells. J Steroid Biochem Mol Biol 1994;50:145-150.
43. Sar M, Stumpf WE, DeLuca H F. Thyrotropes in the pituitary are target cells for 1.25 dihydroxy vitamin D3. Cell Tissue Res. 1980;209:161-166.
44. Chailurkit LO, Aekplakorn W, Ongphiphadhanakul B. High vitamin D status in younger individuals is associated with low circulating thyrotropin. Thyroid 2013;23:25-30. Epub 2012 Dec 16