A stochastic chemical dynamic approach to correlate autoimmunity and optimal vitamin-D range

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Roy, Susmita ^a   Shrinivas, Krishna ^a   Bagchi, Biman ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL; VITAMIN D;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNITY; CELL ACTIVITY; CELL COUNT; CELLULAR IMMUNITY; DENDRITIC CELL; DOSE RESPONSE; EFFECTOR CELL; IMMUNOREGULATION; INNATE IMMUNITY; PATHOGEN CLEARANCE; RISK REDUCTION; STOCHASTIC MODEL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANALOGS AND DERIVATIVES; BIOLOGICAL MODEL; CYTOLOGY; DRUG EFFECTS; HUMAN; IMMUNOLOGY; KINETICS;

ADAPTIVE IMMUNITY; ANTIGEN-PRESENTING CELLS; AUTOIMMUNITY; HUMANS; IMMUNITY, INNATE; KINETICS; MODELS, IMMUNOLOGICAL; T-LYMPHOCYTES; VITAMIN D;

EID: 84903549417     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100635     Document Type: Article

References (75)

1. Autier P, Gandini S (2007) Vitamin D supplementation and total mortality: A metaanalysis of randomized controlled trials. Arch Intern Med 167: 1730-7. (Pubitemid 47403059)
2. Holick MF (2007) Vitamin D deficiency. N Engl J Med 357: 266-281.
3. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, et al. (2011) The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 96: 53-58.
4. Hewison M (2011) Vitamin D and innate and adaptive immunity. Vitam Horm 86: 24-62.
5. Cutolo M, Plebani M, Shoenfeld Y, Adorini L, Tincani A (2011) Vitamin D endocrine system and the immune response in rheumatic diseases. Vitam Horm 86: 327-51.
6. Hewison M (2012) An update on vitamin D and human immunity. Clinical Endocrinology 76, 315-325.
7. Williams CJB (1849) On the use and administration of cod-liver oil in pulmonary consumption. London Journal of Medicine 1: 1-18.
8. Finsen NR (1903) Nobel Prize presentation speech by professor the count K.A.H. Morner, Rector of the Royal Caroline Institute on December 10, 1903.
9. Moller KI, Kongshoj B, Philipsen PA, Thomsen VO, Wulf HC (2005) How Finsen's light cured lupus vulgaris. Photodermatol Photoimmunol Photomed 21: 118-124. (Pubitemid 40775142)
10. Wang TT, Nestel FP, Bourdeau V, Nagai Y, Wang Q, et al. (2004) Cutting edge: 1, 25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 173: 2909-2912. (Pubitemid 39141992)
11. Kamen DL, Tangpricha V (2010) Vitamin D and molecular actions on the immune system: Modulation of innate and autoimmunity. J Mol Med (Berl) 88: 441-450.
12. Bikle D (2009) Nonclassic actions of vitamin D. The Journal of Clinical Endocrinology & Metabolism. 94: 26-34.
13. Dimeloe S, Nanzer A, Ryanna K, Hawrylowicz C (2010) Regulatory T-cells, inflammation and the allergic response-The role of glucocorticoids and vitamin D. J Ster Biochem Mol Bio 120: 86-95.
14. Kamen D, Aranow C (2008) Vitamin D in systemic lupus erythematosus. Curr Opin Rheumatol 20: 532-537.
15. Adorini L (2003) Tolerogenic dendritic cells induced by vitamin D receptor ligands enhance regulatory T-cells inhibiting autoimmune diabetes. Ann N Y Acad Sci 987: 258-261.
16. Reg) T-cells and a pictorial description of complex and coarse-grained network formalism.
17. Jonuleit H, Schmitt E, Steinbrink K, Enk AH (2001) Dendritic cells as a tool to induce anergic and regulatory T-cells. Trends Immunol 22: 394-400. (Pubitemid 32673646)
18. Lutz MB, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23: 445-449. (Pubitemid 35015188)
19. 4+ T-cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192: 1213-1222.
20. Powrie F, Maloy KJ (2003) Regulating the regulators. Science 299: 1030-1031.
21. Piemonti L, Monti P, Sironi M, Fraticelli P, Leone BE, et al. (2000) Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. J Immunol 164: 4443-4451. (Pubitemid 30238038)
22. Penna G, Roncari A, Amuchastegui S, Daniel KC, Berti E, et al. (2005) Expression of the inhibitory receptor ILT3 on dendritic cells is dispensable for induction of CD4+Foxp3+ regulatory T-cells by 1, 25-dihydroxyvitamin D3. Blood 106: 3490-3497. (Pubitemid 41609185)
23. Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, et al. (2001) Regulatory T-cells induced by 1 alpha, 25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 167: 1945-1953. (Pubitemid 32747499)
24. Schuster I, Egger H, Herzig G, Reddy GS, Schmid JA, et al. (2006) Selective inhibitors of vitamin D metabolism -New concepts and perspectives. Anticancer Research 26: 2653-2668. (Pubitemid 44155547)
25. Correale J, Ysrraelit MC, Gaitán MI (2009) Immunomodulatory effects of Vitamin D in multiple sclerosis. Brain 132: 1146-1160.
26. Peelen E, Knippenberg S, Muris AH, Thewissen M, Smolders J, et al. (2011) Effects of vitamin D on the peripheral adaptive immune system: A review. Autoimmunity Reviews 10: 733-743.
27. Lo WC, Arsenescu RI, Friedman A (2013) Mathematical model of the roles of T-cells in inflammatory bowel disease. Bull Math Biol 75: 1417-33.
28. Pillis LD, Caldwell T, Sarapata E, Williams H (2013) Mathematical modeling of regulatory T-cell effects on renal cell carcinoma treatment. Discrete and continuous dynamical systems series B 18: 915-943.
29. Martinez-Pasamar S, Abad E, Moreno B, Mendizabal NVD, Martinez-Forero I, et al. (2013) Dynamic cross-regulation of antigen-specific effector and regulatory T-cell subpopulations and microglia in brain autoimmunity. BMC Systems Biology 7: 34.
30. Fouchet D, Regoes RA (2008) Population dynamics analysis of the interaction between adaptive regulatory T-cells and antigen presenting cells. Plos One 3: e2306.
31. Hopfield JJ (1974) Kinetic Proofreading: A New Mechanism for reducing errors in biosynthetic processes requiring high specificity. Proc Nat Acad Sci USA 71: 4135.
32. Qian H (2003) Thermodynamic and kinetic analysis of sensitivity amplification in biological signal transduction. Biophys Chem 105: 585-93.
33. Chaudhury S, Cao J, Sinitsyn NA (2013) Universality of Poisson indicator and Fano factor of transport event statistics in ion channels and enzyme kinetics. J Phys Chem B 117: 503-509.
34. Wu Z, Xing J (2012) Functional roles of slow enzyme conformational changes in network dynamics. Biophys J 103: 1052-1059.
35. Min W, Xie XS, Bagchi B (2008) Two dimensional reaction free energy surfaces of catalytic reaction: Effects of protein conformational dynamics on enzyme catalysis. J Phys Chem 112: 454-466. (Pubitemid 351184620)
36. Santra M, Bagchi B (2012) Catalysis of tRNA-Aminoacylation: Single turnover to steady state kinetics of tRNA synthetases. J Phys Chem B 116: 11809-11817.
37. Santra M, Bagchi B (2013) Kinetic proofreading at single molecular level: Aminoacylation of tRNAIle and the role of water as an editor. Plos One 8: e66112.
38. Gillespie DT (1976) A general method for numerically simulating the stochastic time evolution of coupled chemical reactions. J Comput Phys 22: 403-434.
39. Turner TE, Schnell S, Burrage K (2004) Stochastic approaches for modelling in vivo reactions. Comput Biol Chem. 28: 165-78.
40. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, et al. (2002) Molecular Biology of the Cell. 4th edition. New York: Garland Science.
41. Christen U, von Herrath MG (2004) Initiation of autoimmunity. Curr Opin Immunol 16(6):759-67. (Pubitemid 39423666)
42. Wilhelm T (2009) The smallest chemical reaction system with bistability. BMC Systems Biology 3: 90.
43. Ghosh S, Banerjee S, Bose I (2012) Emergent bistability: Effects of additive and multiplicative noise. Eur. Phys. J. E 11: 1-14.
44. Whitmire JK, Eam B, Whitton JL (2008) Tentative T-cells: memory cells are quick to respond, but slow to divide. PLoS Pathog. 4:e1000041.
45. von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, et al. (2010) Vitamin D controls T-cell antigen receptor signaling and activation of human T-cells. Nat Immunol 11: 344-9.
46. Cutolo M, Pizzorni C, Sulli A (2011) Vitamin D endocrine system involvement in autoimmune rheumatic diseases. Autoimmunity Reviews 11: 84-87.
47. Opferman JT, Ober BT, Ashton-Rickardt PG (1999) Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 283: 1745-1748.
48. Adorini L (2005) Intervention in autoimmunity: The potential of vitamin D receptor agonists. Cellular Immunology 233: 115-124.
49. Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, et al. (2001) Regulatory T-cells induced by 1 alpha, 25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 167: 1945-1953. (Pubitemid 32747499)
50. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (1995) Immunologic self-tolerance maintained by activated T-cells expressing IL-2 receptor a-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 155: 1151-1164.
51. Leon K, Perez R, Lage A, Carneiro J (2000) Modelling T-cell-mediated suppression dependent on interactions in multicellular conjugates. J Theor Biol 207: 231-254.
52. Jeffery LE, Wood AM, Qureshi OS, Hou TZ, Gardner D, et al. (2012) Availability of 25-Hydroxyvitamin D3 to APCs controls the balance between regulatory and inflammatory T-cell responses. J Immunol 189: 5155-5164.
53. Harris SS (2005) Vitamin D in type 1 diabetes prevention. J Nutr 135: 323-325.
54. Ross AC, Taylor CL, Yaktine AL, Valle HBD (2011) Dietary reference intakes for calcium and vitamin D. Washington, D.C: National Academies Press. 435.
55. Moyad MA (2009) Vitamin D: A Rapid Review. Dermatology Nursing 21(1): 1-11.
56. Stolzenberg-Solomon RZ, Jacobs EJ, Arslan AA, Qi D, Patel AV, et al. (2010) Circulating 25-Hydroxyvitamin D and risk of pancreatic cancer. Am J Epidemiol 172: 81-93.
57. Sanders KM, Nicholson GC, Ebeling PR (2013) Is high dose vitamin D harmful? Calcif Tissue Int 92: 191-206.
58. Hypponen E, Berry DJ, Wjst M, Power C (2009) Serum 25-hydroxyvitamin D and IgE - a significant but nonlinear relationship. Allergy 64: 613-620.
59. Takeyama K, Kitanaka S, Sato T, Kobori M, Yanagisawa J, et al. (1997) 25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis. Science 277: 1827-30.
60. Jones G, Prosser DE, Kaufmann M (2012) 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): Its important role in the degradation of vitamin D. Arch Biochem Biophys. 523: 9-18.
61. Lutz MB, Schuler G (2002) Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends in Immunology 23: 445-449. (Pubitemid 35015188)
62. Das J, Ho M, Zikherman J, Govern C, Yang M, et al. (2009) Digital signaling and hysteresis characterize Ras activation in lymphoid cells. Cell 136: 337-351.
63. Hong T, Xing J, Li L, Tyson JJ (2012) A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T-cells. BMC Systems Biology 6: 66.
64. Min W, Xie XS, Bagchi B (2009) Role of conformational dynamics in kinetics of an enzymatic cycle in a nonequilibrium steady state. J Chem Phys 131: 065104.
65. Qian H, Shi PZ, Xing J (2009) Stochastic bifurcation, slow fluctuations, and bistability as an origin of biochemical complexity. Phys Chem Chem Phys 11: 4861-4870.
66. Sasmal D, Ghosh S, Das A, Bhattacharyya K (2013) Solvation dynamics of biological water in a single live cell under a confocal microscope. Langmuir 29: 2289-2298.
67. Mandlik V, Shinde S, Chaudhary A, Singh S (2012) Biological network modelling identifies IPCS in Leishmania as a therapeutic target. Integr Biol 4: 1130-1142.
68. Jerne NK (1974) Towards a network theory of the immune system. Ann Immunol (Paris) 125C: 373-89.
69. Pike JW, Meyer MB, Bishop KA (2012) Regulation of target gene expression by the vitamin D receptor - an update on mechanisms. Rev Endocr Metab Disord 13: 45-55.
70. Fleet JC (2004) Rapid, membrane-initiated actions of 1, 25 dihydroxyvitamin D: What are they and what do they mean? J Nutr 134: 3215-3218.
71. (b) Fleet JC (2008) Molecular actions of vitamin D contributing to cancer prevention. Mol Aspects Med 29: 388-396.
72. Ling EM, Smith T, Nguyen XD, Pridgeon C, Dallman M, et al. (2004) Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 363: 608-615. (Pubitemid 38264178)
73. Ligthart GJ, Schuit HR, Hijmans W (1985) Subpopulations of mononuclear cells in ageing: expansion of the null cell compartment and decrease in the number of T and B cells in human blood. Immunology 55: 15-21. (Pubitemid 15114581)
74. Bates MF, Khander A, Steigman SA, Tracy TF Jr, Luks FI (2014) Use of white blood cell count and negative appendectomy rate. Pediatrics 133:e39-44.
75. Fearnley DB, Whyte LF, Carnoutsos SA, Cook AH, Hart DN (1999) Monitoring human blood dendritic cell numbers in normal individuals and in stem cell transplantation. Blood 93: 728-36. (Pubitemid 29035756)