-
1
-
-
84898809123
-
The microbiome in inflammatory bowel disease: Current status and the future ahead
-
Kostic AD, Xavier RJ, Gevers D. The microbiome in inflammatory bowel disease: current status and the future ahead. Gastroenterology 2014;146:1489-99.
-
(2014)
Gastroenterology
, vol.146
, pp. 1489-1499
-
-
Kostic, A.D.1
Xavier, R.J.2
Gevers, D.3
-
2
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010;42:1118-25.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
3
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011;43:246-52.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
4
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
Jostins L, Ripke S, Weersma RK, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 2012;491:119-24.
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L.1
Ripke, S.2
Weersma, R.K.3
-
5
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon RK, Tonkonogy S, Schultz M, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998;66:5224-31.
-
(1998)
Infect Immun
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
-
6
-
-
0021835860
-
Role of the faecal stream in the maintenance of Crohn's colitis
-
Harper PH, Lee EC, Kettlewell MG, et al. Role of the faecal stream in the maintenance of Crohn's colitis. Gut 1985;26:279-84.
-
(1985)
Gut
, vol.26
, pp. 279-284
-
-
Harper, P.H.1
Lee, E.C.2
Kettlewell, M.G.3
-
7
-
-
55949124035
-
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
-
Sokol H, Pigneur B, Watterlot L, et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2008;105:16731-6.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16731-16736
-
-
Sokol, H.1
Pigneur, B.2
Watterlot, L.3
-
8
-
-
84930475582
-
Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease
-
Ghouri YA, Richards DM, Rahimi EF, et al. Systematic review of randomized controlled trials of probiotics, prebiotics, and synbiotics in inflammatory bowel disease. Clin Exp Gastroenterol 2014;9:473-87.
-
(2014)
Clin Exp Gastroenterol
, vol.9
, pp. 473-487
-
-
Ghouri, Y.A.1
Richards, D.M.2
Rahimi, E.F.3
-
9
-
-
79958221480
-
Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease
-
Benjamin JL, Hedin CR, Koutsoumpas A, et al. Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease. Gut 2011;60:923-9.
-
(2011)
Gut
, vol.60
, pp. 923-929
-
-
Benjamin, J.L.1
Hedin, C.R.2
Koutsoumpas, A.3
-
10
-
-
0022456910
-
Epidemiology of inflammatory bowel disease
-
Calkins BM, Mendeloff AI. Epidemiology of inflammatory bowel disease. Epidemiol Rev 1986;8:60-91.
-
(1986)
Epidemiol Rev
, vol.8
, pp. 60-91
-
-
Calkins, B.M.1
Mendeloff, A.I.2
-
11
-
-
78650097770
-
Genetics in twins with Crohn's disease: Less pronounced than previously believed?
-
Halfvarson J. Genetics in twins with Crohn's disease: less pronounced than previously believed? Inflamm Bowel Dis 2011;17:6-12.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 6-12
-
-
Halfvarson, J.1
-
12
-
-
84855206901
-
Family studies in Crohn's disease: New horizons in understanding disease pathogenesis, risk and prevention
-
Hedin CR, Stagg AJ, Whelan K, et al. Family studies in Crohn's disease: new horizons in understanding disease pathogenesis, risk and prevention. Gut 2012;61:311-18.
-
(2012)
Gut
, vol.61
, pp. 311-318
-
-
Hedin, C.R.1
Stagg, A.J.2
Whelan, K.3
-
13
-
-
79953748870
-
Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives
-
Joossens M, Huys G, Cnockaert M, et al. Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives. Gut 2011;60:631-7.
-
(2011)
Gut
, vol.60
, pp. 631-637
-
-
Joossens, M.1
Huys, G.2
Cnockaert, M.3
-
14
-
-
84908507536
-
Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings
-
Hedin CR, McCarthy NE, Louis P, et al. Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings. Gut 2014;63:1578-86.
-
(2014)
Gut
, vol.63
, pp. 1578-1586
-
-
Hedin, C.R.1
McCarthy, N.E.2
Louis, P.3
-
15
-
-
79955064481
-
Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities
-
van der Gast CJ, Walker AW, Stressmann FA, et al. Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities. ISME J 2011;5:780-91.
-
(2011)
ISME J
, vol.5
, pp. 780-791
-
-
Van Der Gast, C.J.1
Walker, A.W.2
Stressmann, F.A.3
-
16
-
-
33747073504
-
Microbial diversity in the deep sea and the underexplored "rare biosphere"
-
Sogin ML, Morrison HG, Huber JA, et al. Microbial diversity in the deep sea and the underexplored "rare biosphere". Proc Natl Acad Sci U S A 2006;103:12115-20.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 12115-12120
-
-
Sogin, M.L.1
Morrison, H.G.2
Huber, J.A.3
-
17
-
-
84862197046
-
Analyses of the microbial diversity across the human microbiome
-
Li K, Bihan M, Yooseph S, et al. Analyses of the microbial diversity across the human microbiome. PLoS One 2012;7:e32118.
-
(2012)
PLoS One
, vol.7
-
-
Li, K.1
Bihan, M.2
Yooseph, S.3
-
18
-
-
84883110880
-
Richness of human gut microbiome correlates with metabolic markers
-
Le CE, Nielsen T, Qin J, et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013;500:541-6.
-
(2013)
Nature
, vol.500
, pp. 541-546
-
-
Le, C.E.1
Nielsen, T.2
Qin, J.3
-
19
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
Turnbaugh PJ, Hamady M, Yatsunenko T, et al. A core gut microbiome in obese and lean twins. Nature 2009;457:480-4.
-
(2009)
Nature
, vol.457
, pp. 480-484
-
-
Turnbaugh, P.J.1
Hamady, M.2
Yatsunenko, T.3
-
20
-
-
84891473723
-
Human gut microbiome and risk for colorectal cancer
-
Ahn J, Sinha R, Pei Z, et al. Human gut microbiome and risk for colorectal cancer. J Natl Cancer Inst 2013;105:1907-11.
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 1907-1911
-
-
Ahn, J.1
Sinha, R.2
Pei, Z.3
-
21
-
-
84868193133
-
Reduced gut microbial diversity in early life is associated with later development of eczema but not atopy in high-risk infants
-
Ismail IH, Oppedisano F, Joseph SJ, et al. Reduced gut microbial diversity in early life is associated with later development of eczema but not atopy in high-risk infants. Pediatr Allergy Immunol 2012;23:674-81.
-
(2012)
Pediatr Allergy Immunol
, vol.23
, pp. 674-681
-
-
Ismail, I.H.1
Oppedisano, F.2
Joseph, S.J.3
-
22
-
-
84875047451
-
Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans
-
Biedermann L, Zeitz J, Mwinyi J, et al. Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans. PLoS One 2013;8:e59260.
-
(2013)
PLoS One
, vol.8
-
-
Biedermann, L.1
Zeitz, J.2
Mwinyi, J.3
-
23
-
-
79960279940
-
Promise and pitfalls of the Immunochip
-
Cortes A, Brown MA. Promise and pitfalls of the Immunochip. Arthritis Res Ther 2011;13:101.
-
(2011)
Arthritis Res Ther
, vol.13
, pp. 101
-
-
Cortes, A.1
Brown, M.A.2
-
24
-
-
84871239707
-
REGENT: A risk assessment and classification algorithm for genetic and environmental factors
-
Crouch DJ, Goddard GH, Lewis CM. REGENT: a risk assessment and classification algorithm for genetic and environmental factors. Eur J Hum Genet 2013;21:109-11.
-
(2013)
Eur J Hum Genet
, vol.21
, pp. 109-111
-
-
Crouch, D.J.1
Goddard, G.H.2
Lewis, C.M.3
-
25
-
-
77956256212
-
Risk categorization for complex disorders according to genotype relative risk and precision in parameter estimates
-
Goddard GH, Lewis CM. Risk categorization for complex disorders according to genotype relative risk and precision in parameter estimates. Genet Epidemiol 2010;34:624-32.
-
(2010)
Genet Epidemiol
, vol.34
, pp. 624-632
-
-
Goddard, G.H.1
Lewis, C.M.2
-
26
-
-
84875364582
-
Reducing bias in bacterial community analysis of lower respiratory infections
-
Rogers GB, Cuthbertson L, Hoffman LR, et al. Reducing bias in bacterial community analysis of lower respiratory infections. ISME J 2013;7:697-706.
-
(2013)
ISME J
, vol.7
, pp. 697-706
-
-
Rogers, G.B.1
Cuthbertson, L.2
Hoffman, L.R.3
-
27
-
-
84903478262
-
Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice
-
Rogers GB, Kozlowska J, Keeble J, et al. Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice. Sci Rep 2014;4:5437.
-
(2014)
Sci Rep
, vol.4
, pp. 5437
-
-
Rogers, G.B.1
Kozlowska, J.2
Keeble, J.3
-
28
-
-
53749097505
-
Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP)
-
Dowd SE, Wolcott RD, Sun Y, et al. Polymicrobial nature of chronic diabetic foot ulcer biofilm infections determined using bacterial tag encoded FLX amplicon pyrosequencing (bTEFAP). PLoS One 2008;3:e3326.
-
(2008)
PLoS One
, vol.3
, pp. e3326
-
-
Dowd, S.E.1
Wolcott, R.D.2
Sun, Y.3
-
29
-
-
84965014990
-
-
Vienna A: R: A Language and Environment for Statistical Computing
-
R Core Team. R Foundation for Statistical Computing. Vienna A: R: A Language and Environment for Statistical Computing, 2014.
-
(2014)
R Foundation for Statistical Computing
-
-
-
30
-
-
78649686679
-
A pyrosequencing study in twins shows that GI microbial profiles vary with inflammatory bowel disease phenotypes
-
Willing B, Dicksved J, Halfvarson J, et al. A pyrosequencing study in twins shows that GI microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology 2010;39:1844-54.
-
(2010)
Gastroenterology
, vol.39
, pp. 1844-1854
-
-
Willing, B.1
Dicksved, J.2
Halfvarson, J.3
-
31
-
-
84902150181
-
Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease
-
Rajca S, Grondin V, Louis E, et al. Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn's disease. Inflamm Bowel Dis 2014;20:978-86.
-
(2014)
Inflamm Bowel Dis
, vol.20
, pp. 978-986
-
-
Rajca, S.1
Grondin, V.2
Louis, E.3
-
32
-
-
80054111810
-
Fermentation in the human large intestine: Its physiologic consequences and the potential contribution of prebiotics
-
Macfarlane GT, Macfarlane S. Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics. J Clin Gastroenterol 2011;45(Suppl):S120-7.
-
(2011)
J Clin Gastroenterol
, vol.45
, pp. S120-S127
-
-
Macfarlane, G.T.1
Macfarlane, S.2
-
33
-
-
80054980812
-
Regulation of inflammation by short chain fatty acids
-
Vinolo MA, Rodrigues HG, Nachbar RT, et al. Regulation of inflammation by short chain fatty acids. Nutrients 2011;3:858-76.
-
(2011)
Nutrients
, vol.3
, pp. 858-876
-
-
Vinolo, M.A.1
Rodrigues, H.G.2
Nachbar, R.T.3
-
34
-
-
84866613234
-
Conjugated linoleic acid modulates immune responses in patients with mild to moderately active Crohn's disease
-
Bassaganya-Riera J, Hontecillas R, Horne WT, et al. Conjugated linoleic acid modulates immune responses in patients with mild to moderately active Crohn's disease. Clin Nutr 2012;31:721-7.
-
(2012)
Clin Nutr
, vol.31
, pp. 721-727
-
-
Bassaganya-Riera, J.1
Hontecillas, R.2
Horne, W.T.3
-
35
-
-
84870824919
-
Microbiota of de-novo pediatric IBD: Increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis
-
Hansen R, Russell RK, Reiff C, et al. Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis. Am J Gastroenterol 2012;107:1913-22.
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 1913-1922
-
-
Hansen, R.1
Russell, R.K.2
Reiff, C.3
-
36
-
-
0029115715
-
Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity
-
Rachmilewitz D, Karmeli F, Okon E, et al. Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 1995;37:247-55.
-
(1995)
Gut
, vol.37
, pp. 247-255
-
-
Rachmilewitz, D.1
Karmeli, F.2
Okon, E.3
-
37
-
-
68249110221
-
The role of pH in determining the species composition of the human colonic microbiota
-
Duncan SH, Louis P, Thomson JM, et al. The role of pH in determining the species composition of the human colonic microbiota. Environ Microbiol 2009;11:2112-22.
-
(2009)
Environ Microbiol
, vol.11
, pp. 2112-2122
-
-
Duncan, S.H.1
Louis, P.2
Thomson, J.M.3
-
38
-
-
77954133026
-
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
-
Park JH, Wacholder S, Gail MH, et al. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat Genet 2010;42:570-5.
-
(2010)
Nat Genet
, vol.42
, pp. 570-575
-
-
Park, J.H.1
Wacholder, S.2
Gail, M.H.3
-
39
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009;461:747-53.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
|