Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells

International Journal of Molecular Medicine

Volumn 36, Issue 1, 2015, Pages 113-122

  Li, Lingmei ^a   Qi, Lisha ^a   Liang, Zhijie ^a   Song, Wangzhao ^a   Liu, Yanxue ^a   Wang, Yalei ^a   Sun, Baocun ^a   Zhang, Bin ^a   Cao, Wenfeng ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

CD44; Epidermal growth factor; Epithelial mesenchymal transition; Hyaluronan; Transforming growth factor 1

Indexed keywords

CELL SURFACE RECEPTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HERMES ANTIGEN; HYALURONAN SYNTHASE 1; HYALURONAN SYNTHASE 2; HYALURONAN SYNTHASE 3; HYALURONIC ACID; HYMECROMONE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CD44 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; GLUCURONOSYLTRANSFERASE; HAS1 PROTEIN, HUMAN; HAS2 PROTEIN, HUMAN; HAS3 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; LUNG CANCER; LUNG CANCER CELL LINE; MOLECULAR INTERACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STIMULATION; TRANSACTIVATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BREAST TUMOR; CELL MOTION; DRUG EFFECTS; ENZYME ACTIVATION; FEMALE; GENETICS; HUMAN; LUNG TUMOR; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE; TUMOR CELL LINE; TUMOR INVASION;

ANTIGENS, CD44; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GLUCURONOSYLTRANSFERASE; HUMANS; HYALURONIC ACID; HYMECROMONE; LUNG NEOPLASMS; MCF-7 CELLS; NEOPLASM INVASIVENESS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84930357279     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2222     Document Type: Article

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