FAK and HAS inhibition synergistically decrease colon cancer cell viability and affect expression of critical genes

Anti-Cancer Agents in Medicinal Chemistry

Volumn 13, Issue 4, 2013, Pages 584-594

  Heffler, Melissa ^a   Golubovskaya, Vita M ^a   Conroy, Jeffrey ^b   Liu, Song ^b   Wang, Dan ^b   Cance, William G ^a   Dunn, Kelli B ^c  

^a UNIVERSITY AT BUFFALO   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c University of Louisville School of Medicine   (United States)

Author keywords

Colon cancer; FAK; Gene expression; Hyaluronan; Silenced RNA; Viability

Indexed keywords

FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; HYALURONIC ACID; HYMECROMONE; UNCLASSIFIED DRUG; Y 15;

APOPTOSIS; ARTICLE; BIOINFORMATICS; CELL ADHESION; CELL CYCLE REGULATION; CELL GROWTH; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DRUG EFFICACY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GLUCURONOSYLTRANSFERASE; HUMANS; HYMECROMONE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84876718333     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/1871520611313040008     Document Type: Article

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