Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Landais, Igor ^a   Pelton, Chantel ^a,b   Streblow, Daniel ^a   DeFilippis, Victor ^a   McWeeney, Shannon ^a   Nelson, Jay A ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Oregon Health Care Quality Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA; MICRORNA UL112 3P; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, HUMAN; LIGAND; MICRORNA-UL112, HUMAN CYTOMEGALOVIRUS; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; TLR2 PROTEIN, HUMAN; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LUCIFERASE ASSAY; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; 3' UNTRANSLATED REGION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; CYTOLOGY; CYTOMEGALOVIRUS; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; MONOCYTE; MUTATION; REPORTER GENE; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 5; MUS;

3' UNTRANSLATED REGIONS; CELLS, CULTURED; CYTOMEGALOVIRUS; FIBROBLASTS; GENES, REPORTER; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LIGANDS; MICRORNAS; MONOCYTES; MUTATION; NF-KAPPA B; RECOMBINANT PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA, VIRAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2;

EID: 84930344281     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004881     Document Type: Article

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