Kaposi's sarcoma-associated herpesvirus microRNAs target IRAK1 and MYD88, two components of the toll-like receptor/interleukin-1R signaling cascade, to reduce inflammatory-cytokine expression

Journal of Virology

Volumn 86, Issue 21, 2012, Pages 11663-11674

  Abend, Johanna R ^a,b   Ramalingam, Dhivya ^a   Kieffer Kwon, Philippe ^a   Uldrick, Thomas S ^a   Yarchoan, Robert ^a   Ziegelbauer, Joseph M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; LUCIFERASE; MICRORNA; MICRORNA K12 9; MICRORNA K5; MYELOID DIFFERENTIATION FACTOR 88; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INTRACELLULAR SIGNALING; KAPOSI SARCOMA; MICROARRAY ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TARGETING; WESTERN BLOTTING;

ARTIFICIAL GENE FUSION; BLOTTING, WESTERN; CELL LINE; CYTOKINES; GENE EXPRESSION PROFILING; GENE SILENCING; GENES, REPORTER; HERPESVIRUS 8, HUMAN; HUMANS; IMMUNE EVASION; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKINS; LUCIFERASES; MICROARRAY ANALYSIS; MICRORNAS; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

HERPESVIRIDAE; HUMAN HERPESVIRUS 8;

EID: 84869042446     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01147-12     Document Type: Article

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