-
1
-
-
84885861461
-
Asthma
-
Martinez FD, Vercelli D. Asthma. Lancet. 2013 ; 382 (9901). 1360-1372
-
(2013)
Lancet
, vol.382
, Issue.9901
, pp. 1360-1372
-
-
Martinez, F.D.1
Vercelli, D.2
-
2
-
-
73449086493
-
-
Global Initiative for Asthma (2014, accessed 4 November 2014)
-
Global Initiative for Asthma. Global strategy for asthma management and prevention, www.ginasthma.org(2014, accessed 4 November 2014).
-
Global Strategy for Asthma Management and Prevention
-
-
-
4
-
-
14744284491
-
-
British Thoracic Society/Scottish Intercollegiate Guidelines Network (2014, accessed 4 November 2014)
-
British Thoracic Society/Scottish Intercollegiate Guidelines Network. British guideline on the management of asthma: SIGN 141, https://www.brit-thoracic.org.uk/document-library/clinical-information/asthma/btssign-asthma-guideline-2014/(2014, accessed 4 November 2014).
-
British Guideline on the Management of Asthma: SIGN 141
-
-
-
5
-
-
0000606763
-
Treatment of chronic asthma with prednisolone: Significance of eosinophils in the sputum
-
Morrow Brown H. Treatment of chronic asthma with prednisolone: significance of eosinophils in the sputum. The Lancet. 1958 ; 272 (7059). 1245-1247
-
(1958)
The Lancet
, vol.272
, Issue.7059
, pp. 1245-1247
-
-
Morrow Brown, H.1
-
6
-
-
78049457548
-
Uniform definition of asthma severity, control, and exacerbations: Document presented for the world health organization consultation on severe asthma
-
Bousquet J, Mantzouranis E, Cruz AA, et al. Uniform definition of asthma severity, control, and exacerbations: document presented for the world health organization consultation on severe asthma. J Allergy Clin Immunol. 2010 ; 126 (5). 926-938
-
(2010)
J Allergy Clin Immunol
, vol.126
, Issue.5
, pp. 926-938
-
-
Bousquet, J.1
Mantzouranis, E.2
Cruz, A.A.3
-
7
-
-
84886735709
-
Pharmacotherapy of critical asthma syndrome: Current and emerging therapies
-
Albertson TE, Schivo M, Gidwani N, et al. Pharmacotherapy of critical asthma syndrome: current and emerging therapies. Clin Rev Allergy Immunol. 2015 ; 48 (1). 7-30
-
(2015)
Clin Rev Allergy Immunol
, vol.48
, Issue.1
, pp. 7-30
-
-
Albertson, T.E.1
Schivo, M.2
Gidwani, N.3
-
8
-
-
84874146470
-
What do we know about asthma triggers? a review of the literature
-
Vernon MK, Wiklund I, Bell JA, et al. What do we know about asthma triggers? a review of the literature. J Asthma. 2012 ; 49 (10). 991-998
-
(2012)
J Asthma
, vol.49
, Issue.10
, pp. 991-998
-
-
Vernon, M.K.1
Wiklund, I.2
Bell, J.A.3
-
9
-
-
0034564587
-
Inhaled short acting beta2-agonist use in asthma: Regular vs as needed treatment
-
Walters EH, Walters J. Inhaled short acting beta2-agonist use in asthma: regular vs as needed treatment. Cochrane Database Syst Rev. 2000 ; (4). CD001285
-
(2000)
Cochrane Database Syst Rev
, Issue.4
, pp. 001285
-
-
Walters, E.H.1
Walters, J.2
-
11
-
-
84870625063
-
Asthma exacerbations: Prevention is better than cure
-
Shaw DE, Green RH, Bradding P. Asthma exacerbations: prevention is better than cure. Ther Clin Risk Manag. 2005 ; 1 (4). 273-277
-
(2005)
Ther Clin Risk Manag
, vol.1
, Issue.4
, pp. 273-277
-
-
De, S.1
Green, R.H.2
Bradding, P.3
-
12
-
-
84892510629
-
Eosinophilic phenotypes of airway disease
-
Pavord ID. Eosinophilic phenotypes of airway disease. Ann Am Thorac Soc. 2013 ; 10: S143 - S149
-
(2013)
Ann Am Thorac Soc
, vol.10
, pp. 143-S149
-
-
Pavord, I.D.1
-
13
-
-
84891685199
-
Combination corticosteroid/beta-agonist inhaler as reliever therapy: A solution for intermittent and mild asthma?
-
Beasley R, Weatherall M, Shirtcliffe P, et al. Combination corticosteroid/beta-agonist inhaler as reliever therapy: a solution for intermittent and mild asthma?. J Allergy Clin Immunol. 2014 ; 133 (1). 39-41
-
(2014)
J Allergy Clin Immunol
, vol.133
, Issue.1
, pp. 39-41
-
-
Beasley, R.1
Weatherall, M.2
Shirtcliffe, P.3
-
14
-
-
33747805014
-
Pharmacological management of mild or moderate persistent asthma
-
O'Byrne PM, Parameswaran K. Pharmacological management of mild or moderate persistent asthma. Lancet. 2006 ; 368 (9537). 794-803
-
(2006)
Lancet
, vol.368
, Issue.9537
, pp. 794-803
-
-
O'Byrne, P.M.1
Parameswaran, K.2
-
16
-
-
33751062503
-
Rapid effects of inhaled corticosteroids in acute asthma: An evidence-based evaluation
-
Rodrigo GJ. Rapid effects of inhaled corticosteroids in acute asthma: an evidence-based evaluation. Chest. 2006 ; 130 (5). 1301-1311
-
(2006)
Chest
, vol.130
, Issue.5
, pp. 1301-1311
-
-
Rodrigo, G.J.1
-
17
-
-
0037471787
-
Early intervention with budesonide in mild persistent asthma: A randomised, double-blind trial
-
Pauwels RA, Pedersen S, Busse WW, et al. Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet. 2003 ; 361 (9363). 1071-1076
-
(2003)
Lancet
, vol.361
, Issue.9363
, pp. 1071-1076
-
-
Pauwels, R.A.1
Pedersen, S.2
Busse, W.W.3
-
18
-
-
0035888721
-
Low dose inhaled budesonide and formoterol in mild persistent asthma: The optima randomized trial
-
O'Byrne PM, Barnes PJ, Rodriguez-Roisin R, et al. Low dose inhaled budesonide and formoterol in mild persistent asthma: the optima randomized trial. Am J Respir Crit Care Med. 2001 ; 164 (8 Pt 1). 1392-1397
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1392-1397
-
-
O'Byrne, P.M.1
Barnes, P.J.2
Rodriguez-Roisin, R.3
-
19
-
-
0034601431
-
Low-dose inhaled corticosteroids and the prevention of death from asthma
-
Suissa S, Ernst P, Benayoun S, et al. Low-dose inhaled corticosteroids and the prevention of death from asthma. N Engl J Med. 2000 ; 343 (5). 332-336
-
(2000)
N Engl J Med
, vol.343
, Issue.5
, pp. 332-336
-
-
Suissa, S.1
Ernst, P.2
Benayoun, S.3
-
20
-
-
1842533220
-
Dose-response relationship of inhaled budesonide in adult asthma: A meta-analysis
-
Masoli M, Holt S, Weatherall M, et al. Dose-response relationship of inhaled budesonide in adult asthma: a meta-analysis. Eur Respir J. 2004 ; 23 (4). 552-558
-
(2004)
Eur Respir J
, vol.23
, Issue.4
, pp. 552-558
-
-
Masoli, M.1
Holt, S.2
Weatherall, M.3
-
21
-
-
0037416286
-
Inhaled corticosteroid doses in asthma: An evidence-based approach
-
Powell H, Gibson PG. Inhaled corticosteroid doses in asthma: an evidence-based approach. Med J Aust. 2003 ; 178 (5). 223-225
-
(2003)
Med J Aust
, vol.178
, Issue.5
, pp. 223-225
-
-
Powell, H.1
Gibson, P.G.2
-
22
-
-
1842370350
-
Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and corticosteroids establishing therapy (FACET) international study group
-
Pauwels RA, Lofdahl CG, Postma DS, et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and corticosteroids establishing therapy (FACET) international study group. N Engl J Med. 1997 ; 337 (20). 1405-1411
-
(1997)
N Engl J Med
, vol.337
, Issue.20
, pp. 1405-1411
-
-
Pauwels, R.A.1
Lofdahl, C.G.2
Postma, D.S.3
-
23
-
-
21844449700
-
Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children
-
Ni Chroinin M, Greenstone I, Lasserson TJ, et al. Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children. Cochrane Database Syst Rev. 2009 ; (4). CD005307
-
(2009)
Cochrane Database Syst Rev
, Issue.4
, pp. 005307
-
-
Ni Chroinin, M.1
Greenstone, I.2
Lasserson, T.J.3
-
24
-
-
62949243372
-
Comparison of inhaled corticosteroids: An update
-
Kelly HW. Comparison of inhaled corticosteroids: an update. Ann Pharmacother. 2009 ; 43 (3). 519-527
-
(2009)
Ann Pharmacother
, vol.43
, Issue.3
, pp. 519-527
-
-
Kelly, H.W.1
-
25
-
-
19644363824
-
Asthma: One hundred years of treatment and onward
-
Chu EK, Drazen JM. Asthma: one hundred years of treatment and onward. Am J Respir Crit Care Med. 2005 ; 171 (11). 1202-1208
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.11
, pp. 1202-1208
-
-
Chu, E.K.1
Drazen, J.M.2
-
26
-
-
0033590513
-
Treatment of asthma with drugs modifying the leukotriene pathway
-
Drazen JM, Israel E, O'Byrne PM. Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med. 1999 ; 340 (3). 197-206
-
(1999)
N Engl J Med
, vol.340
, Issue.3
, pp. 197-206
-
-
Drazen, J.M.1
Israel, E.2
O'Byrne, P.M.3
-
27
-
-
79955716906
-
Leukotriene antagonists as first-line or add-on asthma-controller therapy
-
Price D, Musgrave SD, Shepstone L, et al. Leukotriene antagonists as first-line or add-on asthma-controller therapy. N Engl J Med. 2011 ; 364 (18). 1695-1707
-
(2011)
N Engl J Med
, vol.364
, Issue.18
, pp. 1695-1707
-
-
Price, D.1
Musgrave, S.D.2
Shepstone, L.3
-
28
-
-
84864507034
-
Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
-
Chauhan BF, Ducharme FM. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev. 2012 ; (5). CD002314
-
(2012)
Cochrane Database Syst Rev
, Issue.5
, pp. 002314
-
-
Chauhan, B.F.1
Ducharme, F.M.2
-
29
-
-
84922136593
-
Medication adherence and the risk of severe asthma exacerbations: A systematic review
-
Engelkes M, Janssens HM, de Jongste JC, et al. Medication adherence and the risk of severe asthma exacerbations: a systematic review. Eur Respir J. 2015 ; 45 (2). 396-407
-
(2015)
Eur Respir J
, vol.45
, Issue.2
, pp. 396-407
-
-
Engelkes, M.1
Janssens, H.M.2
De Jongste, J.C.3
-
30
-
-
82555176659
-
Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence
-
Williams LK, Peterson EL, Wells K, et al. Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence. J Allergy Clin Immunol. 2011 ; 128 (6). 1185-1191
-
(2011)
J Allergy Clin Immunol
, vol.128
, Issue.6
, pp. 1185-1191
-
-
Williams, L.K.1
Peterson, E.L.2
Wells, K.3
-
31
-
-
20144388867
-
Daily versus as-needed corticosteroids for mild persistent asthma
-
Boushey HA, Sorkness CA, King TS, et al. Daily versus as-needed corticosteroids for mild persistent asthma. N Engl J Med. 2005 ; 352 (15). 1519-1528
-
(2005)
N Engl J Med
, vol.352
, Issue.15
, pp. 1519-1528
-
-
Boushey, H.A.1
Sorkness, C.A.2
King, T.S.3
-
32
-
-
23644451043
-
Daily inhaled corticosteroid treatment should not be prescribed for mild persistent asthma. Con
-
Boushey HA.. Daily inhaled corticosteroid treatment should not be prescribed for mild persistent asthma. Con. Am J Respir Crit Care Med. 2005 ; 172 (4). 412-414
-
(2005)
Am J Respir Crit Care Med
, vol.172
, Issue.4
, pp. 412-414
-
-
Boushey, H.A.1
-
33
-
-
23644451043
-
Daily inhaled corticosteroid treatment should be prescribed for mild persistent asthma. Pro
-
O'Byrne PM.. Daily inhaled corticosteroid treatment should be prescribed for mild persistent asthma. Pro. Am J Respir Crit Care Med. 2005 ; 172 (4). 410-412
-
(2005)
Am J Respir Crit Care Med
, vol.172
, Issue.4
, pp. 410-412
-
-
O'Byrne, P.M.1
-
34
-
-
84874164698
-
Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
-
Chauhan BF, Chartrand C, Ducharme FM. Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults. Cochrane Database Syst Rev. 2012; ; (12). CD009611
-
(2012)
Cochrane Database Syst Rev
, Issue.12
, pp. 009611
-
-
Chauhan, B.F.1
Chartrand, C.2
Ducharme, F.M.3
-
36
-
-
34249021521
-
Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma
-
Papi A, Canonica GW, Maestrelli P, et al. Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma. N Engl J Med. 2007 ; 356 (20). 2040-2052
-
(2007)
N Engl J Med
, vol.356
, Issue.20
, pp. 2040-2052
-
-
Papi, A.1
Canonica, G.W.2
Maestrelli, P.3
-
37
-
-
84866129261
-
Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The basalt randomized controlled trial
-
Calhoun WJ, Ameredes BT, King TS, et al. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the basalt randomized controlled trial. JAMA. 2012 ; 308 (10). 987-997
-
(2012)
JAMA
, vol.308
, Issue.10
, pp. 987-997
-
-
Calhoun, W.J.1
Ameredes, B.T.2
King, T.S.3
-
38
-
-
66649117717
-
Rescue treatment in asthma. More than as-needed bronchodilation
-
Papi A, Caramori G, Adcock IM, et al. Rescue treatment in asthma. More than as-needed bronchodilation. Chest. 2009 ; 135 (6). 1628-1633
-
(2009)
Chest
, vol.135
, Issue.6
, pp. 1628-1633
-
-
Papi, A.1
Caramori, G.2
Adcock, I.M.3
-
39
-
-
84877026665
-
Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial
-
Patel M, Pilcher J, Travers J, et al. Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial. J Allergy Clin Immunol Pract. 2013 ; 1 (1). 83-91
-
(2013)
J Allergy Clin Immunol Pract
, vol.1
, Issue.1
, pp. 83-91
-
-
Patel, M.1
Pilcher, J.2
Travers, J.3
-
40
-
-
5144221336
-
Can guideline-defined asthma control be achieved? the gaining optimal asthma control study
-
Bateman ED, Boushey HA, Bousquet J, et al. Can guideline-defined asthma control be achieved? the gaining optimal asthma control study. Am J Respir Crit Care Med. 2004 ; 170 (8). 836-844
-
(2004)
Am J Respir Crit Care Med
, vol.170
, Issue.8
, pp. 836-844
-
-
Bateman, E.D.1
Boushey, H.A.2
Bousquet, J.3
-
42
-
-
1142309474
-
Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies
-
Stoloff SW, Stempel DA, Meyer J, et al. Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies. J Allergy Clin Immunol. 2004 ; 113 (2). 245-251
-
(2004)
J Allergy Clin Immunol
, vol.113
, Issue.2
, pp. 245-251
-
-
Stoloff, S.W.1
Stempel, D.A.2
Meyer, J.3
-
43
-
-
77956370272
-
Randomized controlled trial of adherence with single or combination inhaled corticosteroid/long-acting beta-agonist inhaler therapy in asthma
-
Perrin K, Williams M, Wijesinghe M, et al. Randomized controlled trial of adherence with single or combination inhaled corticosteroid/long-acting beta-agonist inhaler therapy in asthma. J Allergy Clin Immunol. 2010 ; 126 (3). 505-510
-
(2010)
J Allergy Clin Immunol
, vol.126
, Issue.3
, pp. 505-510
-
-
Perrin, K.1
Williams, M.2
Wijesinghe, M.3
-
44
-
-
77954916313
-
The safety of long-acting beta-agonists: More evidence is needed
-
Kazani S, Ware JH, Drazen JM, et al. The safety of long-acting beta-agonists: more evidence is needed. Respirology. 2010 ; 15 (6). 881-885
-
(2010)
Respirology
, vol.15
, Issue.6
, pp. 881-885
-
-
Kazani, S.1
Ware, J.H.2
Drazen, J.M.3
-
45
-
-
77950481806
-
The FDA and safe use of long-acting beta-agonists in the treatment of asthma
-
Chowdhury BA, Dal Pan G. The FDA and safe use of long-acting beta-agonists in the treatment of asthma. N Engl J Med. 2010 ; 362 (13). 1169-1171
-
(2010)
N Engl J Med
, vol.362
, Issue.13
, pp. 1169-1171
-
-
Chowdhury, B.A.1
Dal Pan, G.2
-
46
-
-
12144270425
-
Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma
-
O'Byrne PM, Bisgaard H, Godard PP, et al. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am J Respir Crit Care Med. 2005 ; 171 (2). 129-136
-
(2005)
Am J Respir Crit Care Med
, vol.171
, Issue.2
, pp. 129-136
-
-
O'Byrne, P.M.1
Bisgaard, H.2
Godard, P.P.3
-
47
-
-
84877087842
-
Beclometasone-formoterol as maintenance and reliever treatment in patients with asthma: A double-blind, randomised controlled trial
-
Papi A, Corradi M, Pigeon-Francisco C, et al. Beclometasone-formoterol as maintenance and reliever treatment in patients with asthma: a double-blind, randomised controlled trial. Lancet Respir Med. 2013 ; 1: 23-31
-
(2013)
Lancet Respir Med
, vol.1
, pp. 23-31
-
-
Papi, A.1
Corradi, M.2
Pigeon-Francisco, C.3
-
48
-
-
84877093623
-
Efficacy and safety of maintenance and reliever combination budesonide-formoterol inhaler in patients with asthma at risk of severe exacerbations: A randomised controlled trial
-
Patel M, Pilcher J, Pritchard A, et al. Efficacy and safety of maintenance and reliever combination budesonide-formoterol inhaler in patients with asthma at risk of severe exacerbations: a randomised controlled trial. Lancet Respir Med. 2013 ; 1: 32-42
-
(2013)
Lancet Respir Med
, vol.1
, pp. 32-42
-
-
Patel, M.1
Pilcher, J.2
Pritchard, A.3
-
49
-
-
33747761653
-
Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: A randomised controlled, double-blind study
-
Rabe KF, Atienza T, Magyar P, et al. Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study. Lancet. 2006 ; 368 (9537). 744-753
-
(2006)
Lancet
, vol.368
, Issue.9537
, pp. 744-753
-
-
Rabe, K.F.1
Atienza, T.2
Magyar, P.3
-
50
-
-
84886530641
-
Combination ICS/fast-onset LABA inhaler as maintenance and reliever therapy: The future for uncontrolled adult asthma?
-
Patel M, Pilcher J, Beasley R. Combination ICS/fast-onset LABA inhaler as maintenance and reliever therapy: the future for uncontrolled adult asthma?. Expert Rev Respir Med. 2013 ; 7 (5). 451-454
-
(2013)
Expert Rev Respir Med
, vol.7
, Issue.5
, pp. 451-454
-
-
Patel, M.1
Pilcher, J.2
Beasley, R.3
-
51
-
-
84900996232
-
Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma
-
Chauhan BF, Ducharme FM. Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma. Cochrane Database Syst Rev. 2014 ; 1: CD003137
-
(2014)
Cochrane Database Syst Rev
, vol.1
, pp. 003137
-
-
Chauhan, B.F.1
Ducharme, F.M.2
-
52
-
-
84862024217
-
Untangling asthma phenotypes and endotypes
-
Agache I, Akdis C, Jutel M, et al. Untangling asthma phenotypes and endotypes. Allergy. 2012 ; 67 (7). 835-846
-
(2012)
Allergy
, vol.67
, Issue.7
, pp. 835-846
-
-
Agache, I.1
Akdis, C.2
Jutel, M.3
-
54
-
-
84860679595
-
Asthma phenotypes: The evolution from clinical to molecular approaches
-
Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med. 2012 ; 18 (5). 716-725
-
(2012)
Nat Med
, vol.18
, Issue.5
, pp. 716-725
-
-
Wenzel, S.E.1
-
55
-
-
48249085691
-
Cluster analysis and clinical asthma phenotypes
-
Haldar P, Pavord ID, Shaw DE, et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med. 2008 ; 178 (3). 218-224
-
(2008)
Am J Respir Crit Care Med
, vol.178
, Issue.3
, pp. 218-224
-
-
Haldar, P.1
Pavord, I.D.2
De, S.3
-
56
-
-
69249098135
-
Distinct clinical phenotypes of airways disease defined by cluster analysis
-
Weatherall M, Travers J, Shirtcliffe PM, et al. Distinct clinical phenotypes of airways disease defined by cluster analysis. Eur Respir J. 2009 ; 34 (4). 812-818
-
(2009)
Eur Respir J
, vol.34
, Issue.4
, pp. 812-818
-
-
Weatherall, M.1
Travers, J.2
Shirtcliffe, P.M.3
-
57
-
-
0037202790
-
Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
-
Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet. 2002 ; 360 (9347). 1715-1721
-
(2002)
Lancet
, vol.360
, Issue.9347
, pp. 1715-1721
-
-
Green, R.H.1
Brightling, C.E.2
McKenna, S.3
-
58
-
-
84885172146
-
Which biomarkers are effective for identifying Th2-driven inflammation in asthma?
-
Diamant Z, Tufvesson E, Bjermer L. Which biomarkers are effective for identifying Th2-driven inflammation in asthma?. Curr Allergy Asthma Rep. 2013 ; 13 (5). 477-486
-
(2013)
Curr Allergy Asthma Rep
, vol.13
, Issue.5
, pp. 477-486
-
-
Diamant, Z.1
Tufvesson, E.2
Bjermer, L.3
-
59
-
-
79551505136
-
Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome
-
Lotvall J, Akdis CA, Bacharier LB, et al. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol. 2011 ; 127 (2). 355-360
-
(2011)
J Allergy Clin Immunol
, vol.127
, Issue.2
, pp. 355-360
-
-
Lotvall, J.1
Akdis, C.A.2
Bacharier, L.B.3
-
60
-
-
14744293163
-
Pharmacogenetic approaches in the treatment of asthma
-
Sayers I, Hall IP. Pharmacogenetic approaches in the treatment of asthma. Curr Allergy Asthma Rep. 2005 ; 5 (2). 101-108
-
(2005)
Curr Allergy Asthma Rep
, vol.5
, Issue.2
, pp. 101-108
-
-
Sayers, I.1
Hall, I.P.2
-
61
-
-
84859180524
-
Genetic basis for personalized medicine in asthma
-
Portelli M, Sayers I. Genetic basis for personalized medicine in asthma. Expert Rev Respir Med. 2012 ; 6 (2). 223-236
-
(2012)
Expert Rev Respir Med
, vol.6
, Issue.2
, pp. 223-236
-
-
Portelli, M.1
Sayers, I.2
-
62
-
-
84919840145
-
Inhaler reminders improve adherence with controller treatment in primary care patients with asthma
-
Foster JM, Usherwood T, Smith L, et al. Inhaler reminders improve adherence with controller treatment in primary care patients with asthma. J Allergy Clin Immunol. 2014 ; 134 (6). 1260-1268
-
(2014)
J Allergy Clin Immunol
, vol.134
, Issue.6
, pp. 1260-1268
-
-
Foster, J.M.1
Usherwood, T.2
Smith, L.3
-
63
-
-
84919650525
-
Treatment adherence in asthmatic patients: The last frontier?
-
Bateman ED. Treatment adherence in asthmatic patients: the last frontier?. J Allergy Clin Immunol. 2014 ; 134 (6). 1269-1270
-
(2014)
J Allergy Clin Immunol
, vol.134
, Issue.6
, pp. 1269-1270
-
-
Bateman, E.D.1
-
64
-
-
84907424700
-
Anti-interleukin-5 monoclonal antibody to treat severe eosinophilic asthma
-
Nair P. Anti-interleukin-5 monoclonal antibody to treat severe eosinophilic asthma. N Engl J Med. 2014 ; 371 (13). 1249-1251
-
(2014)
N Engl J Med
, vol.371
, Issue.13
, pp. 1249-1251
-
-
Nair, P.1
-
65
-
-
84871651058
-
Fluticasone/formoterol combination therapy versus budesonide/formoterol for the treatment of asthma: A randomized, controlled, non-inferiority trial of efficacy and safety
-
Bodzenta-Lukaszyk A, Buhl R, Balint B, et al. Fluticasone/formoterol combination therapy versus budesonide/formoterol for the treatment of asthma: a randomized, controlled, non-inferiority trial of efficacy and safety. J Asthma. 2012 ; 49 (10). 1060-1070
-
(2012)
J Asthma
, vol.49
, Issue.10
, pp. 1060-1070
-
-
Bodzenta-Lukaszyk, A.1
Buhl, R.2
Balint, B.3
-
66
-
-
34147160761
-
Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma
-
Papi A, Paggiaro PL, Nicolini G, et al. Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma. Eur Respir J. 2007 ; 29 (4). 682-689
-
(2007)
Eur Respir J
, vol.29
, Issue.4
, pp. 682-689
-
-
Papi, A.1
Paggiaro, P.L.2
Nicolini, G.3
-
67
-
-
84877615735
-
Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the beta2 agonist vilanterol administered once daily for 52 weeks in patients >=12 years old with asthma: A randomised trial
-
Busse WW, O'Byrne PM, Bleecker ER, et al. Safety and tolerability of the novel inhaled corticosteroid fluticasone furoate in combination with the beta2 agonist vilanterol administered once daily for 52 weeks in patients >=12 years old with asthma: a randomised trial. Thorax. 2013 ; 68 (6). 513-520
-
(2013)
Thorax
, vol.68
, Issue.6
, pp. 513-520
-
-
Busse, W.W.1
O'Byrne, P.M.2
Bleecker, E.R.3
-
68
-
-
33745383646
-
The dose-response characteristics of inhaled corticosteroids when used to treat asthma: An overview of cochrane systematic reviews
-
Adams NP, Jones PW. The dose-response characteristics of inhaled corticosteroids when used to treat asthma: an overview of cochrane systematic reviews. Respir Med. 2006 ; 100 (8). 1297-1306
-
(2006)
Respir Med
, vol.100
, Issue.8
, pp. 1297-1306
-
-
Adams, N.P.1
Jones, P.W.2
-
70
-
-
84900432516
-
Omalizumab for severe asthma: Efficacy beyond the atopic patient?
-
Domingo C. Omalizumab for severe asthma: efficacy beyond the atopic patient?. Drugs. 2014 ; 74 (5). 521-533
-
(2014)
Drugs
, vol.74
, Issue.5
, pp. 521-533
-
-
Domingo, C.1
-
71
-
-
84922561723
-
Omalizumab in asthma: An update on recent developments
-
Humbert M, Busse W, Hanania NA, et al. Omalizumab in asthma: an update on recent developments. J Allergy Clin Immunol Pract. 2014 ; 2 (5). 525-536
-
(2014)
J Allergy Clin Immunol Pract
, vol.2
, Issue.5
, pp. 525-536
-
-
Humbert, M.1
Busse, W.2
Hanania, N.A.3
-
72
-
-
84866758536
-
Tiotropium in asthma poorly controlled with standard combination therapy
-
Kerstjens HA, Engel M, Dahl R, et al. Tiotropium in asthma poorly controlled with standard combination therapy. N Engl J Med. 2012 ; 367 (13). 1198-1207
-
(2012)
N Engl J Med
, vol.367
, Issue.13
, pp. 1198-1207
-
-
Kerstjens, H.A.1
Engel, M.2
Dahl, R.3
-
73
-
-
84929041797
-
What is the role of tiotropium in asthma? A systematic review with meta-analysis
-
Rodrigo GJ, Castro-Rodriguez JA. What is the role of tiotropium in asthma? A systematic review with meta-analysis. Chest. 2014 ;:
-
(2014)
Chest
-
-
Rodrigo, G.J.1
Castro-Rodriguez, J.A.2
-
74
-
-
84905463184
-
The role of macrolides in asthma: Current evidence and future directions
-
Wong EH, Porter JD, Edwards MR, et al. The role of macrolides in asthma: current evidence and future directions. Lancet Respir Med. 2014 ; 2 (8). 657-670
-
(2014)
Lancet Respir Med
, vol.2
, Issue.8
, pp. 657-670
-
-
Wong, E.H.1
Porter, J.D.2
Edwards, M.R.3
-
75
-
-
84875219719
-
Azithromycin for prevention of exacerbations in severe asthma (AZISAST): A multicentre randomised double-blind placebo-controlled trial
-
Brusselle GG, Vanderstichele C, Jordens P, et al. Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial. Thorax. 2013 ; 68 (4). 322-329
-
(2013)
Thorax
, vol.68
, Issue.4
, pp. 322-329
-
-
Brusselle, G.G.1
Vanderstichele, C.2
Jordens, P.3
-
76
-
-
84902147234
-
The impact of azithromycin therapy on the airway microbiota in asthma
-
Slater M, Rivett DW, Williams L, et al. The impact of azithromycin therapy on the airway microbiota in asthma. Thorax. 2014 ; 69 (7). 673-674
-
(2014)
Thorax
, vol.69
, Issue.7
, pp. 673-674
-
-
Slater, M.1
Rivett, D.W.2
Williams, L.3
-
77
-
-
80052829963
-
Diagnosis and definition of severe refractory asthma: An international consensus statement from the Innovative Medicine Initiative (IMI)
-
Bel EH, Sousa A, Fleming L, et al. Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI). Thorax. 2011 ; 66 (10). 910-917
-
(2011)
Thorax
, vol.66
, Issue.10
, pp. 910-917
-
-
Bel, E.H.1
Sousa, A.2
Fleming, L.3
-
78
-
-
33747750597
-
The mechanisms, diagnosis, and management of severe asthma in adults
-
Holgate ST, Polosa R. The mechanisms, diagnosis, and management of severe asthma in adults. Lancet. 2006 ; 368 (9537). 780-793
-
(2006)
Lancet
, vol.368
, Issue.9537
, pp. 780-793
-
-
Holgate, S.T.1
Polosa, R.2
-
79
-
-
85016765389
-
Methotrexate as a steroid sparing agent for asthma in adults
-
Davies H, Olson L, Gibson P. Methotrexate as a steroid sparing agent for asthma in adults. Cochrane Database Syst Rev. 2000 ; 2: CD000391
-
(2000)
Cochrane Database Syst Rev
, vol.2
, pp. 000391
-
-
Davies, H.1
Olson, L.2
Gibson, P.3
-
80
-
-
2942744527
-
Azathioprine as an oral corticosteroid sparing agent for asthma
-
Dean T, Dewey A, Bara A, et al. Azathioprine as an oral corticosteroid sparing agent for asthma. Cochrane Database Syst Rev. 2004 ; 1: CD003270
-
(2004)
Cochrane Database Syst Rev
, vol.1
, pp. 003270
-
-
Dean, T.1
Dewey, A.2
Bara, A.3
-
81
-
-
0037501014
-
Cyclosporin as an oral corticosteroid sparing agent in stable asthma
-
Evans DJ, Cullinan P, Geddes DM. Cyclosporin as an oral corticosteroid sparing agent in stable asthma. Cochrane Database Syst Rev. 2001 ; 2: CD002993
-
(2001)
Cochrane Database Syst Rev
, vol.2
, pp. 002993
-
-
Evans, D.J.1
Cullinan, P.2
Geddes, D.M.3
-
83
-
-
84879401471
-
Dupilumab in persistent asthma with elevated eosinophil levels
-
Wenzel S, Ford L, Pearlman D, et al. Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med. 2013 ; 368 (26). 2455-2466
-
(2013)
N Engl J Med
, vol.368
, Issue.26
, pp. 2455-2466
-
-
Wenzel, S.1
Ford, L.2
Pearlman, D.3
-
84
-
-
84907423833
-
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma
-
Bel EH, Wenzel SE, Thompson PJ, et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med. 2014 ; 371 (13). 1189-1197
-
(2014)
N Engl J Med
, vol.371
, Issue.13
, pp. 1189-1197
-
-
Bel, E.H.1
Wenzel, S.E.2
Thompson, P.J.3
-
85
-
-
84907424177
-
Mepolizumab treatment in patients with severe eosinophilic asthma
-
Ortega HG, Liu MC, Pavord ID, et al. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med. 2014 ; 371 (13). 1198-1207
-
(2014)
N Engl J Med
, vol.371
, Issue.13
, pp. 1198-1207
-
-
Ortega, H.G.1
Liu, M.C.2
Pavord, I.D.3
-
86
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
-
Pavord ID, Korn S, Howarth P, et al. Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet. 2012 ; 380 (9842). 651-659
-
(2012)
Lancet
, vol.380
, Issue.9842
, pp. 651-659
-
-
Pavord, I.D.1
Korn, S.2
Howarth, P.3
-
87
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren J, Lemanske RF, Hanania NA, et al. Lebrikizumab treatment in adults with asthma. N Engl J Med. 2011 ; 365 (12). 1088-1098
-
(2011)
N Engl J Med
, vol.365
, Issue.12
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
-
88
-
-
84901848274
-
Defining phenotypes in asthma: A step towards personalized medicine
-
Chung KF. Defining phenotypes in asthma: a step towards personalized medicine. Drugs. 2014 ; 74 (7). 719-728
-
(2014)
Drugs
, vol.74
, Issue.7
, pp. 719-728
-
-
Chung, K.F.1
-
89
-
-
84856845581
-
Severe asthma: From characteristics to phenotypes to endotypes
-
Wenzel S. Severe asthma: from characteristics to phenotypes to endotypes. Clin Exp Allergy. 2012 ; 42 (5). 650-658
-
(2012)
Clin Exp Allergy
, vol.42
, Issue.5
, pp. 650-658
-
-
Wenzel, S.1
-
90
-
-
80053565899
-
Approaches to stepping up and stepping down care in asthmatic patients
-
Thomas A, Lemanske RF, Jackson DJ. Approaches to stepping up and stepping down care in asthmatic patients. J Allergy Clin Immunol. 2011 ; 128 (5). 915-924
-
(2011)
J Allergy Clin Immunol
, vol.128
, Issue.5
, pp. 915-924
-
-
Thomas, A.1
Lemanske, R.F.2
Jackson, D.J.3
-
91
-
-
0037901033
-
Stepping down inhaled corticosteroids in asthma: Randomised controlled trial
-
Hawkins G, McMahon AD, Twaddle S, et al. Stepping down inhaled corticosteroids in asthma: randomised controlled trial. BMJ. 2003 ; 326 (7399). 1115
-
(2003)
BMJ
, vol.326
, Issue.7399
, pp. 1115
-
-
Hawkins, G.1
McMahon, A.D.2
Twaddle, S.3
-
92
-
-
77953928883
-
Down-titration from high-dose combination therapy in asthma: Removal of long-acting beta(2)-agonist
-
Reddel HK, Gibson PG, Peters MJ, et al. Down-titration from high-dose combination therapy in asthma: removal of long-acting beta(2)-agonist. Respir Med. 2010 ; 104 (8). 1110-1120
-
(2010)
Respir Med
, vol.104
, Issue.8
, pp. 1110-1120
-
-
Reddel, H.K.1
Gibson, P.G.2
Peters, M.J.3
-
93
-
-
84867342482
-
Long-acting beta2-agonist step-off in patients with controlled asthma
-
Brozek JL, Kraft M, Krishnan JA, et al. Long-acting beta2-agonist step-off in patients with controlled asthma. Arch Intern Med. 2012 ; 172 (18). 1365-1375
-
(2012)
Arch Intern Med
, vol.172
, Issue.18
, pp. 1365-1375
-
-
Brozek, J.L.1
Kraft, M.2
Krishnan, J.A.3
-
95
-
-
84875230783
-
The risk of asthma exacerbation after stopping low-dose inhaled corticosteroids: A systematic review and meta-analysis of randomized controlled trials
-
Rank MA, Hagan JB, Park MA, et al. The risk of asthma exacerbation after stopping low-dose inhaled corticosteroids: a systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol. 2013 ; 131 (3). 724-729
-
(2013)
J Allergy Clin Immunol
, vol.131
, Issue.3
, pp. 724-729
-
-
Ma, R.1
Hagan, J.B.2
Ma, P.3
-
96
-
-
0035922827
-
Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering corticosteroids in asthma
-
Brocklebank D, Wright J, Cates C. Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering corticosteroids in asthma. BMJ. 2001 ; 323 (7318). 896-900
-
(2001)
BMJ
, vol.323
, Issue.7318
, pp. 896-900
-
-
Brocklebank, D.1
Wright, J.2
Cates, C.3
-
97
-
-
0035922757
-
Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering beta (2)agonists bronchodilators in asthma
-
Ram FS, Wright J, Brocklebank D, et al. Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering beta (2)agonists bronchodilators in asthma. BMJ. 2001 ; 323 (7318). 901-905
-
(2001)
BMJ
, vol.323
, Issue.7318
, pp. 901-905
-
-
Ram, F.S.1
Wright, J.2
Brocklebank, D.3
-
98
-
-
0034763042
-
Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: A systematic review of the literature
-
Brocklebank D, Ram F, Wright J, et al. Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature. Health Technol Assess. 2001 ; 5 (26). 1-149
-
(2001)
Health Technol Assess
, vol.5
, Issue.26
, pp. 1-149
-
-
Brocklebank, D.1
Ram, F.2
Wright, J.3
-
99
-
-
0141886534
-
Inhaled corticosteroids for asthma therapy: Patient compliance, devices, and inhalation technique
-
Cochrane MG, Bala MV, Downs KE, et al. Inhaled corticosteroids for asthma therapy: patient compliance, devices, and inhalation technique. Chest. 2000 ; 117 (2). 542-550
-
(2000)
Chest
, vol.117
, Issue.2
, pp. 542-550
-
-
Cochrane, M.G.1
Bala, M.V.2
Downs, K.E.3
-
100
-
-
84909634510
-
Effects of small airway dysfunction on the clinical expression of asthma: A focus on asthma symptoms and bronchial hyper-responsiveness
-
van der Wiel E, Postma DS, van der Molen T, et al. Effects of small airway dysfunction on the clinical expression of asthma: a focus on asthma symptoms and bronchial hyper-responsiveness. Allergy. 2014 ; 69 (12). 1681-1688
-
(2014)
Allergy
, vol.69
, Issue.12
, pp. 1681-1688
-
-
Van Der Wiel, E.1
Postma, D.S.2
Van Der Molen, T.3
-
101
-
-
84906954413
-
Small airways dysfunction in asthma: Evaluation and management to improve asthma control
-
Usmani OS. Small airways dysfunction in asthma: evaluation and management to improve asthma control. Allergy Asthma Immunol Res. 2014 ; 6 (5). 376-388
-
(2014)
Allergy Asthma Immunol Res
, vol.6
, Issue.5
, pp. 376-388
-
-
Usmani, O.S.1
-
102
-
-
49149126491
-
Ciclesonide: A review of its use in the management of asthma
-
Deeks ED, Perry CM. Ciclesonide: a review of its use in the management of asthma. Drugs. 2008 ; 68 (12). 1741-1770
-
(2008)
Drugs
, vol.68
, Issue.12
, pp. 1741-1770
-
-
Deeks, E.D.1
Perry, C.M.2
-
103
-
-
33745459272
-
Inhaled mometasone furoate: A review of its use in persistent asthma in adults and adolescents
-
McCormack PL, Plosker GL. Inhaled mometasone furoate: a review of its use in persistent asthma in adults and adolescents. Drugs. 2006 ; 66 (8). 1151-1168
-
(2006)
Drugs
, vol.66
, Issue.8
, pp. 1151-1168
-
-
McCormack, P.L.1
Plosker, G.L.2
-
104
-
-
84890289336
-
Inhaled corticosteroids and the risk of pneumonia in people with asthma: A case-control study
-
McKeever T, Harrison TW, Hubbard R, et al. Inhaled corticosteroids and the risk of pneumonia in people with asthma: a case-control study. Chest. 2013 ; 144 (6). 1788-1794
-
(2013)
Chest
, vol.144
, Issue.6
, pp. 1788-1794
-
-
McKeever, T.1
Harrison, T.W.2
Hubbard, R.3
-
105
-
-
77956354206
-
Role of viral respiratory infections in asthma and asthma exacerbations
-
Busse WW, Lemanske RF, Gern JE. Role of viral respiratory infections in asthma and asthma exacerbations. Lancet. 2010 ; 376 (9743). 826-834
-
(2010)
Lancet
, vol.376
, Issue.9743
, pp. 826-834
-
-
Busse, W.W.1
Lemanske, R.F.2
Gern, J.E.3
-
106
-
-
79952015893
-
Viruses and bacteria in acute asthma exacerbations-A GA(2) LEN-DARE systematic review
-
Papadopoulos NG, Christodoulou I, Rohde G, et al. Viruses and bacteria in acute asthma exacerbations-a GA(2) LEN-DARE systematic review. Allergy. 2011 ; 66 (4). 458-468
-
(2011)
Allergy
, vol.66
, Issue.4
, pp. 458-468
-
-
Papadopoulos, N.G.1
Christodoulou, I.2
Rohde, G.3
-
107
-
-
84875545528
-
Vaccines for preventing influenza in people with asthma
-
Cates CJ, Rowe BH. Vaccines for preventing influenza in people with asthma. Cochrane Database Syst Rev. 2013 ; 2: CD000364
-
(2013)
Cochrane Database Syst Rev
, vol.2
, pp. 000364
-
-
Cates, C.J.1
Rowe, B.H.2
-
108
-
-
84930335663
-
-
Public Health England (2014, accessed 4 November 2014)
-
Public Health England. Influenza: the Green Book Chapter 19, https://www.gov.uk/government/publications/influenza-the-green-book-chapter-19(2014, accessed 4 November 2014).
-
Influenza: The Green Book Chapter 19
-
-
-
109
-
-
34247844420
-
The influence of cigarette smoking on adult asthma outcomes
-
Eisner MD, Iribarren C. The influence of cigarette smoking on adult asthma outcomes. Nicotine Tob Res. 2007 ; 9 (1). 53-56
-
(2007)
Nicotine Tob Res
, vol.9
, Issue.1
, pp. 53-56
-
-
Eisner, M.D.1
Iribarren, C.2
|