Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells

Aging Cell

Volumn 14, Issue 4, 2015, Pages 689-697

  Takebayashi, Shin Ichiro ^a,d   Tanaka, Hiroshi ^a   Hino, Shinjiro ^a   Nakatsu, Yuko ^a   Igata, Tomoka ^a   Sakamoto, Akihisa ^a   Narita, Masashi ^b   Nakao, Mitsuyoshi ^a,c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d MIE UNIVERSITY   (Japan)

Author keywords

Gene regulation; Glycolysis; Metabolic remodeling; Oncogene induced senescence; Oxidative phosphorylation; Retinoblastoma protein

Indexed keywords

DNA; GLUCOSE; GLYCOLYTIC ENZYME; INTERLEUKIN 6; INTERLEUKIN 8; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 5; OXYGEN; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA;

ARTICLE; CAPILLARY ELECTROPHORESIS; CELL AGING; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA REPLICATION; DOWN REGULATION; FATTY ACID OXIDATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE KNOCKDOWN; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; METABOLOME; MICROARRAY ANALYSIS; ONCOGENE; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME OF FLIGHT MASS SPECTROMETRY; TRANSCRIPTION REGULATION; TRIPLE QUADRUPOLE MASS SPECTROMETRY; UPREGULATION; CITRIC ACID CYCLE; DEFICIENCY; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; ONCOGENE RAS; PATHOLOGY; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL AGING; CELL LINE, TUMOR; CITRIC ACID CYCLE; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; GLYCOLYSIS; HUMANS; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; RESPIRATORY MUCOSA; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION;

EID: 84930323338     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12351     Document Type: Article

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