In vivo tomographic imaging of deep-seated cancer using fluorescence lifetime contrast

Cancer Research

Volumn 75, Issue 7, 2015, Pages 1236-1243

  Rice, William L ^a   Shcherbakova, Daria M ^b   Verkhusha, Vladislav V ^b,c   Kumar, Anand T N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; NEAR INFRARED FLUORESCENT PROTEIN; UNCLASSIFIED DRUG; PHOTOPROTEIN; RED FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; BACTERIAL CELL; BRAIN METASTASIS; CAMERA; CANCER CELL; CONTROLLED STUDY; FEMALE; IMAGE PROCESSING; IMAGE RECONSTRUCTION; IMAGING SYSTEM; IN VITRO STUDY; IN VIVO STUDY; LASER; LUNG METASTASIS; MONITORING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TOMOGRAPHY; ADENOCARCINOMA; ANIMAL; BIOSYNTHESIS; BRAIN TUMOR; CANCER TRANSPLANTATION; CELL TRACKING; HUMAN; LUNG TUMOR; NUDE MOUSE; OPTICAL TOMOGRAPHY; PATHOLOGY; RAT; SECONDARY; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL TRACKING; FEMALE; HUMANS; LUMINESCENT PROTEINS; LUNG NEOPLASMS; MICE, NUDE; NEOPLASM TRANSPLANTATION; RATS; TOMOGRAPHY, OPTICAL;

EID: 84930233458     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-3001     Document Type: Article

References (34)

1. Chudakov DM, Matz MV, Lukyanov S, Lukyanov KA. Fluorescent proteins and their applications in imaging living cells and tissues. Physiol Rev 2010;90:1103-63.
2. Hoffman RM, Yang M. Whole-body imaging with fluorescent proteins. Nat Protoc 2006;1:1429-38.
3. Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, et al. Volumetric tomography of fluorescent proteins through small animals in vivo. Proc Natl Acad Sci U S A 2005;102:18252-7.
4. Yang M, Baranov E, Li XM, Wang JW, Jiang P, Li L, et al. Whole-body and intravital optical imaging of angiogenesis in orthotopically implanted tumors. Proc Natl Acad Sci U S A 2001;98:2616-21.
5. Bloch S, Lesage F, McIntosh L, Gandjbakhche A, Liang KX, Achilefu S. Whole-body fluorescence lifetime imaging of a tumor-targeted near-infrared molecular probe in mice. J Biomed Opt 2005;10:054003.
6. Weissleder R, Tung CH, Mahmood U, Bogdanov A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 1999;17:375-8.
7. Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, et al. Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo. Circulation 2007;115:1384-91.
8. Goergen CJ, Chen HH, Bogdanov A, Sosnovik DE, Kumar ATN. In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium. J Biomed Opt 2012;17:056001.
9. Shcherbakova DM, Verkhusha VV. Near-infrared fluorescent proteins for multicolor in vivo imaging. Nat Methods 2013;10:751-4.
10. Piatkevich KD, Subach FV, Verkhusha VV. Far-red light photoactivatable near-infrared fluorescent proteins engineered from a bacterial phytochrome. Nat Commun 2013;4:2153.
11. Filonov GS, Verkhusha VV. A near-infrared BiFC reporter for in vivo imaging of protein-protein interactions. Chem Biol 2013;20:1078-86.
12. Deliolanis NC, Ale A, Morscher S, Burton NC, Schaefer K, Radrich K, et al. Deep-tissue reporter-gene imaging with fluorescence and optoacoustic tomography: a performance overview. Mol Imaging Biol 2014;16:652-60.
13. Jiguet-Jiglaire C, Cayol M, Mathieu S, Jeanneau C, Bouvier-Labit C, Ouafik L, et al. Noninvasive near-infrared fluorescent protein-based imaging of tumor progression and metastases in deep organs and intraosseous tissues. J Biomed Opt 2014;19:16019.
14. Talmadge JE, Singh RK, Fidler IJ, Raz A. Murine models to evaluate novel and conventional therapeutic strategies for cancer. Am J Pathol 2007;170:793-804.
15. Marx V. Probes: seeing in the near infrared. Nat Methods 2014;11:717-20.
16. Lakowicz JR, Masters BR. Principles of fluorescence spectroscopy, Third Edition. J Biomed Opt 2008;13:029901.
17. Kumar ATN, Raymond SB, Dunn AK, Bacskai BJ, Boas D. a. A time domain fluorescence tomography system for small animal imaging. IEEE Trans Med Imaging 2008;27:1152-63.
18. Kumar ATN, Chung E, Raymond SB, van de Water J, Shah K, Fukumura D, et al. Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett 2009;34:2066-8.
19. Venugopal V, Chen J, Lesage F, Intes X. Full-field time-resolved fluorescence tomography of small animals. Opt Lett 2010;35:3189-91.
20. Raymond SB, Boas DA, Bacskai BJ, Kumar ATN. Lifetime-based tomographic multiplexing. J Biomed Opt 2010;15:046011.
21. Rice WL, Kumar ATN. Preclinical whole body time domain fluorescence lifetime multiplexing of fluorescent proteins. J Biomed Opt 2014;19:046005.
22. Kumar AT, Raymond SB, Boverman G, Boas DA, Bacskai BJ. Time resolved fluorescence tomography of turbid media based on lifetime contrast. Opt Express 2006;14:12255-70.
23. Hou SS, Rice WL, Bacskai BJ, Kumar ATN. Tomographic lifetime imaging using combined early- and late-arriving photons. Opt Lett 2014;39:3-7.
24. Arridge SR, Schotland JC. Optical tomography: forward and inverse problems. Inverse Probl 2009;25:123010.
25. Fang Q, Boas DA. Monte Carlo simulation of photon migration in 3D turbid media accelerated by graphics processing units. Opt Express 2009;17:20178-90.
26. Hyde D, Miller EL, Brooks DH, Ntziachristos V. Data specific spatially varying regularization for multimodal fluorescence molecular tomography. IEEE Trans Med Imaging 2010;29:365-74.
27. Kumar ATN. Direct Monte Carlo computation of time-resolved fluorescence in heterogeneous turbid media. Opt Lett 2012;37:4783-5.
28. Oku N, Sugawara M, Tsukada H, Irimura T, Okada S. Positron emission tomography analysis of metastatic tumor cell trafficking. Cancer Res 1994;54:2573-6.
29. Winnard PT, Kluth JB, Raman V. Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer. Neoplasia 2006;8:796-806.
30. Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V. Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications. J Biomed Opt 2008;13:044008.
31. Radrich K, Ale A, Ermolayev V, Ntziachristos V. Improving limited-projection-angle fluorescence molecular tomography using a co-registered x-ray computed tomography scan. J Biomed Opt 2012;17:126011.
32. Le Dévédec SE, van Roosmalen W, Maria N, Grimbergen M, Pont C, Lalai R, et al. An improved model to study tumor cell autonomous metastasis programs using MTLn3 cells and the Rag2(-/-) gammac (-/-) mouse. Clin Exp Metastasis 2009;26:673-84.
33. Kodack DP, Chung E, Yamashita H, Incio J, Duyverman A, Song Y, et al. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proc Natl Acad Sci U S A 2012;109:E3119-27.
34. Begley CG, Ellis LM. Drug development: raise standards for preclinical cancer research. Nature 2012;483:531-3.