Lifetime-based tomographic multiplexing

Journal of Biomedical Optics

Volumn 15, Issue 4, 2010, Pages

  Raymond, Scott B ^a   Boas, David A ^b   Bacskai, Brian J ^b   Kumar, Anand T N ^b  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Lifetime; Near infrared fluorescence; Small animal imaging; Tomography

Indexed keywords

EMISSION SPECTRUMS; FLUORESCENCE DECAYS; FORWARD MODELS; FREE-SPACE TRANSMISSION; IN-VIVO; INTENSIFIED CHARGE COUPLED DEVICES; LIFE-TIME DISTRIBUTION; LIFETIME; MONOEXPONENTIAL DECAY; NEAR-INFRARED FLUORESCENCE; NUDE MICE; ORGAN SYSTEMS; QUANTITATIVE SEPARATION; RELATIVE CONCENTRATION; SMALL ANIMAL IMAGING; SOLUTION MIXTURES; TI: SAPPHIRE LASER; TIME DOMAIN; TOMOGRAPHIC; TOMOGRAPHIC IMAGING;

EMISSION SPECTROSCOPY; FLUORESCENCE; INFRARED DEVICES; LASER EXCITATION; MAMMALS; MULTIPLEXING; TOMOGRAPHY;

FLUOROPHORES;

ANIMALIA; MUS MUSCULUS;

FLUORESCENT DYE;

ANIMAL; ARTICLE; COMPUTER ASSISTED DIAGNOSIS; FLUORESCENCE MICROSCOPY; METHODOLOGY; MOUSE; NUDE MOUSE; OPTICAL TOMOGRAPHY; WHOLE BODY IMAGING;

ANIMALS; FLUORESCENT DYES; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; TOMOGRAPHY, OPTICAL; WHOLE BODY IMAGING;

EID: 79952202469     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3469797     Document Type: Article

References (30)

1. G. Gaietta, T. J. Deerinck, S. R. Adams, J. Bouwer, O. Tour, D. W. Laird, G. E. Sosinsky, R. Y. Tsien, and M. H. Ellisman, "Multicolor and electron microscopic imaging of connexin trafficking," Science 296, 503-507 (2002). (Pubitemid 34408665)
2. B. J. Bacskai, S. T. Kajdasz, R. H. Christie, C. Carter, D. Games, P. Seubert, D. Schenk, and B. T. Hyman, "Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy," Nat. Med. 7, 369-372 (2001). (Pubitemid 32224356)
3. B. Huang, S. A. Jones, B. Brandenburg, and X. Zhuang, "Whole-cell 3d storm reveals interactions between cellular structures with nanometer-scale resolution," Nat. Methods 5, 1047-1052 (2008).
4. X. Gao, Y. Cui, R. M. Levenson, L. W. Chung, and S. Nie, "In vivo cancer targeting and imaging with semiconductor quantum dots," Nat. Biotechnol. 22, 969-976 (2004). (Pubitemid 39014473)
5. S. V. Patwardhan and J. P. Culver, "Quantitative diffuse optical tomography for small animals using an ultrafast gated image intensifier," J. Biomed. Opt. 13, 011009 (2008).
6. S. Bloch, F. Lesage, L. McIntosh, A. Gandjbakhche, K. Liang, and S. Achilefu, "Whole-body fluorescence lifetime imaging of a tumortargeted near-infrared molecular probe in mice," J. Biomed. Opt. 10, 054003 (2005).
7. A. T. N. Kumar, J. Skoch, B. J. Bacskai, D. A. Boas, and A. K. Dunn, "Fluorescence-lifetime-based tomography for turbid media," Opt. Lett. 30, 3347-3349 (2005). (Pubitemid 43099199)
8. W. Akers, F. Lesage, D. Holten, and S. Achilefu, "In vivo resolution of multiexponential decays of multiple near-infrared molecular probes by fluorescence lifetime-gated whole-body time-resolved diffuse optical imaging," Mol. Imaging 6, 237-246 (2007). (Pubitemid 47509828)
9. C. D. Salthouse, F. Reynolds, J. M. Tam, L. Josephson, and U. Mahmood, "Quantitative measurement of protease activity with correction of probe delivery and tissue absorption effects," Sens. Actuators B 138, 591-597 (2009).
10. D. J. Hall, U. Sunar, S. Farshchi-Heydari, and S. H. Han, "In vivo simultaneous monitoring of two fluorophores with lifetime contrast using a full-field time domain system," Appl. Opt. 48, D74-D78 (2009).
11. A. T. N. Kumar, S. B. Raymond, G. Boverman, D. A. Boas, and B. J. Bacskai, "Time resolved fluorescence tomography of turbid media based on lifetime contrast," Opt. Express 14, 12255-12270 (2006). (Pubitemid 44907567)
12. A. T. N. Kumar, S. B. Raymond, A. K. Dunn, B. J. Bacskai, and D. A. Boas, "A time domain fluorescence tomography system for small animal imaging," IEEE Trans. Med. Imaging 27, 1152-1163 (2008).
13. D. Hyde, E. Miller, D. H. Brooks, and V. Ntziachristos, "A statistical approach to inverting the born ratio," IEEE Trans. Med. Imaging 26, 893-905 (2007). (Pubitemid 47147237)
14. D. A. Boas, J. P. Culver, J. J. Stott, and A. K. Dunn, "Three dimensional monte carlo code for photon migration through complex heterogeneous media including the adult human head," Opt. Express 10, 159-170 (2002).
15. D. A. Boas, T. Gaudette, and S. R. Arridge, "Simultaneous imaging and optode calibration with diffuse optical tomography," Opt. Express 8, 263-270 (2001).
16. P. K. Yalavarthy, B. W. Pogue, H. Dehghani, and K. D. Paulsen, "Weight-matrix structured regularization provides optimal generalized least-squares estimate in diffuse optical tomography," Med. Phys. 34, 2085-2098 (2007). (Pubitemid 47055744)
17. W. J. Akers, M. Y. Berezin, H. Lee, and S. Achilefu, "Predicting in vivo fluorescence lifetime behavior of near-infrared fluorescent contrast agents using in vitro measurements," J. Biomed. Opt. 13, 054042 (2008).
18. M. Hassan, J. Riley, V. Chernomordik, P. Smith, R. Pursley, S. B. Lee, J. Capala, and A. H. Gandjbakhche, "Fluorescence lifetime imaging system for in vivo studies," Mol. Imaging 6, 229-236 (2007). (Pubitemid 47509827)
19. R. J. Goiffon, W. J. Akers, M. Y. Berezin, H. Lee, and S. Achilefu, "Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging," J. Biomed. Opt. 14, 020501 (2009).
20. W. H. Press, S. A. Teukolsky, W. T. Vetterling, and B. P. Flannery, Numerical Recipes in C: the Art of Scientific Computing, 2nd ed., Cambridge University Press, New York (1992).
21. R. E. Nothdurft, S. V. Patwardhan, W. Akers, Y. Ye, S. Achilefu, and J. P. Culver, "In vivo fluorescence lifetime tomography," J. Biomed. Opt. 14, 024004 (2009).
22. J. Wu, L. Perelman, R. R. Dasari, and M. S. Feld, "Fluorescence tomographic imaging in turbid media using early-arriving photons and laplace transforms," Proc. Natl. Acad. Sci. U.S.A. 94, 8783 (1997).
23. F. Gao, H. Zhao, Y. Tanikawa, and Y. Yamada, "A linear, featureddata scheme for image reconstruction in time domain fluorescence molecular tomography," Opt. Express 14, 7109-7124 (2006). (Pubitemid 44188513)
24. S. Lam, F. Lesage, and X. Intes, "Time domain fluorescent diffuse optical tomography: analytical expressions," Opt. Express 13, 2263-2275 (2005). (Pubitemid 40899186)
25. A. T. N. Kumar, E. Chung, S. B. Raymond, J. van de Water, K. Shah, R. K. Jain, B. J. Bacskai, and D. A. Boas, "Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast," Opt. Lett. 34, 2066-2068 (2009).
26. N. Deliolanis, T. Lasser, D. Hyde, A. Soubret, J. Ripoll, and V. Ntziachristos, "Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections," Opt. Lett. 32, 382-384 (2007). (Pubitemid 46354030)
27. B. J. Bacskai, J. Skoch, G. A. Hickey, and B. T. Hyman, "Fluorescence resonance energy transfer determinations using multiphoton fluorescence lifetime imaging microscopy to characterize amyloidbeta plaques," J. Biomed. Opt. 8, 368-375 (2003).
28. S. B. Raymond, J. Skoch, I. D. Hills, E. E. Nesterov, T. M. Swager, and B. J. Bacskai, "Smart optical probes for near-infrared fluorescence imaging of alzheimer's disease pathology," Eur. J. Nucl. Med. Mol. Imaging 35, 1032-1032 (2008).
29. C. D. Wilms and J. Eilers, "Photo-physical properties of ca2+- indicator dyes suitable for two-photon fluorescence-lifetime recordings," J. Microsc. 225, 209-213 (Mar 2007). (Pubitemid 46437208)
30. K. V. Kuchibhotla, C. R. Lattarulo, B. T. Hyman, and B. J. Bacskai, "Synchronous hyperactivity and intercellular calcium waves in astrocytes in alzheimer mice," Science 323, 1211-1215 (2009).