In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium

Journal of Biomedical Optics

Volumn 17, Issue 5, 2012, Pages

  Goergen, Craig J ^a   Chen, Howard H ^a   Bogdanov Jr , Alexei ^b   Sosnovik, David E ^a   Kumar, Anand T N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Lifetime; Myocardium; Near infrared fluorescence; Protease

Indexed keywords

BIOLOGICAL MARKER; CATHEPSIN; DIAGNOSTIC AGENT; POLYMER;

ANIMAL; ARTICLE; C57BL MOUSE; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETIC PROCEDURES; HEART INFARCTION; METABOLISM; METHODOLOGY; MOLECULAR IMAGING; MOUSE; SPECTROFLUOROMETRY;

ANIMALS; BIOLOGICAL MARKERS; CATHEPSINS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MOLECULAR IMAGING; MOLECULAR PROBE TECHNIQUES; MYOCARDIAL INFARCTION; POLYMERS; SPECTROMETRY, FLUORESCENCE;

EID: 84866793229     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.JBO.17.5.056001     Document Type: Article

References (31)

1. V. Ntziachristos et al., "Looking and listening to light: the evolution of whole-body photonic imaging," Nat. Biotechnol. 23(3), 313-320 (2005). (Pubitemid 41094419)
2. D. E. Sosnovik, M. Nahrendorf, and R. Weissleder, "Targeted imaging of myocardial damage," Nat. Clin. Pract. Cardiovasc. Med. 5(Suppl 2), S63-S70 (2008).
3. M. Solomon et al., "Detection of enzyme activity in orthotopic murine breast cancer by fluorescence lifetime imaging using a fluorescence resonance energy transfer-based molecular probe," J. Biomed. Opt. 16(6), 066019 (2011).
4. D. E. Sosnovik et al., "Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo," Circulation 115(11), 1384-1391 (2007). (Pubitemid 46661480)
5. M. Nahrendorf et al., "Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct," Circ. Res. 100(8), 1218-1225 (2007). (Pubitemid 46684135)
6. J. R. Lakowicz, Principles of Fluorescence Spectroscopy, 2nd Ed., Springer, New York, NY (1999).
7. R. Weissleder et al., "In vivo imaging of tumors with protease-activated near-infrared fluorescent probes," Nat. Biotechnol. 17(4), 375-378 (1999). (Pubitemid 29166041)
8. A. T. N. Kumar et al., "A time domain fluorescence tomography system for small animal imaging," IEEE Trans. Med. Imag. 27(8), 1152-1163 (2008).
9. P. I. Bastiaens and A. Squire, "Fluorescence lifetime imaging microscopy: spatial resolution of biochemical processes in the cell," Trends Cell Biol. 9(2), 48-52 (1999). (Pubitemid 29151791)
10. D. J. Hall et al., "In vivo simultaneous monitoring of two fluorophores with lifetime contrast using a full-field time domain system," Appl. Opt. 48(10), D74-D78 (2009).
11. M. Y. Berezin et al., "Near-infrared fluorescence lifetime ph-sensitive probes," Biophys. J. 100(8), 2063-2072 (2011).
12. R. J. Goiffon et al., "Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging," J. Biomed. Opt. 14(2), 020501 (2009).
13. R. E. Nothdurft et al., "In vivo fluorescence lifetime tomography," J. Biomed. Opt. 14(2), 024004 (2009).
14. S. B. Raymond et al., "Lifetime-based tomographic multiplexing," J. Biomed. Opt. 15(4), 046011 (2010).
15. D. J. Hall et al., "Dynamic optical imaging of metabolic and NADPH oxidase-derived superoxide in live mouse brain using fluorescence lifetime unmixing," J. Cereb. Blood Flow Metab. 32(1), 23-32 (2011).
16. P. R. Selvin, "The renaissance of fluorescence resonance energy transfer," Nat. Struct. Biol. 7(9), 730-734 (2000).
17. W. Akers et al., "In vivo resolution of multiexponential decays of multiple near-infrared molecular probes by fluorescence lifetime-gated whole-body time-resolved diffuse optical imaging," Mol. Imag. 6(4), 237-246 (2007). (Pubitemid 47509828)
18. A. T. N. Kumar et al., "Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast," Opt. Lett. 34(13), 2066-2068 (2009).
19. U. Mahmood et al., "Near-infrared optical imaging of protease activity for tumor detection," Radiology 213(3), 866-870 (1999).
20. C. H. Tung et al., "In vivo imaging of proteolytic enzyme activity using a novel molecular reporter," Cancer Res. 60(17), 4953-4958 (2000).
21. C. H. Tung et al., "Preparation of a cathepsin d sensitive near-infrared fluorescence probe for imaging," Bioconjug. Chem. 10(5), 892-896 (1999).
22. C. Bremer, C. H. Tung, and R. Weissleder, "In vivo molecular target assessment of matrix metalloproteinase inhibition," Nat. Med. 7(6), 743-748 (2001). (Pubitemid 32588033)
23. E. Marecos, R. Weissleder, and A. Bogdanov Jr., "Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model," Bioconjug. Chem. 9(2), 184-191 (1998). (Pubitemid 28147135)
24. A. A. Bogdanov, Jr. et al., "A new macromolecule as a contrast agent for MR angiography: preparation, properties and animal studies," Radiology 187(3), 701-706 (1993). (Pubitemid 23155697)
25. L. H. Michael et al., "Myocardial ischemia and reperfusion: a murine model," Am. J. Physiol. 269(6 Pt. 2), H2147-H2154 (1995). (Pubitemid 26023233)
26. A. L. Rusanov et al., "Lifetime imaging of FRET between red fluorescent proteins," J. Biophoton. 3(12), 774-783 (2010).
27. M. Ogawa et al., "H-type dimer formation of fluorophores: a mechanism for activatable, in vivo optical molecular imaging," ACS Chem. Biol. 4(7), 535-546 (2009).
28. M. Y. Berezin and S. Achilefu, "Fluorescence lifetime measurements and biological imaging," Chem. Rev. 110(5), 2641-2684 (2010).
29. A. Almutairi et al., "Biodegradable ph-sensing dendritic nanoprobes for near-infrared fluorescence lifetime and intensity imaging," J. Am. Chem. Soc. 130(2), 444-445 (2008). (Pubitemid 351455550)
30. R. Alford et al., "Fluorescence lifetime imaging of activatable target specific molecular probes," Contrast Media Mol. Imaging 5(1), 1-8 (2010).
31. N. N. Malouf et al., "Adult-derived stem cells from the liver become myocytes in the heart in vivo," Am. J. Pathol. 158(6), 1929-1935 (2001). (Pubitemid 32545175)