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Volumn 5, Issue , 2015, Pages

Intrathecal curcumin attenuates pain hypersensitivity and decreases spinal neuroinflammation in rat model of monoarthritis

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CCL2 PROTEIN, RAT; CURCUMIN; IL1B PROTEIN, RAT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1;

EID: 84930226712     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10278     Document Type: Article
Times cited : (74)

References (61)
  • 1
    • 33644901007 scopus 로고    scopus 로고
    • Multiple biological activities of curcumin: A short review
    • Maheshwari, R. K., Singh, A. K., Gaddipati, J. & Srimal, R. C. Multiple biological activities of curcumin: a short review. Life Sci. 78, 2081-2087 (2006).
    • (2006) Life Sci. , vol.78 , pp. 2081-2087
    • Maheshwari, R.K.1    Singh, A.K.2    Gaddipati, J.3    Srimal, R.C.4
  • 2
    • 38349011007 scopus 로고    scopus 로고
    • Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials
    • Strimpakos, A. S. & Sharma, R. A. Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials. Antioxid Redox Signal 10, 511-545 (2008).
    • (2008) Antioxid Redox Signal , vol.10 , pp. 511-545
    • Strimpakos, A.S.1    Sharma, R.A.2
  • 3
    • 64549130895 scopus 로고    scopus 로고
    • Evaluation of antihyperalgesic efect of curcumin on formalin-induced orofacial pain in rat
    • Mittal, N., Joshi, R., Hota, D. & Chakrabarti, A. Evaluation of antihyperalgesic efect of curcumin on formalin-induced orofacial pain in rat. Phytother Res. 23, 507-512 (2009).
    • (2009) Phytother Res. , vol.23 , pp. 507-512
    • Mittal, N.1    Joshi, R.2    Hota, D.3    Chakrabarti, A.4
  • 4
    • 53649108512 scopus 로고    scopus 로고
    • The efect of curcumin (active substance of turmeric) on the acetic acid-induced visceral nociception in rats
    • Tajik, H., Tamaddonfard, E. & Hamzeh-Gooshchi, N. The efect of curcumin (active substance of turmeric) on the acetic acid-induced visceral nociception in rats. Pak. J. Biol. Sci. 11, 312-314 (2008).
    • (2008) Pak. J. Biol. Sci. , vol.11 , pp. 312-314
    • Tajik, H.1    Tamaddonfard, E.2    Hamzeh-Gooshchi, N.3
  • 5
    • 84879445731 scopus 로고    scopus 로고
    • Curcumin could prevent the development of chronic neuropathic pain in rats with peripheral nerve injury
    • Jeon, Y. et al. Curcumin could prevent the development of chronic neuropathic pain in rats with peripheral nerve injury. Curr. Ter. Res. Clin. Exp. 74, 1-4 (2013).
    • (2013) Curr. Ter. Res. Clin. Exp. , vol.74 , pp. 1-4
    • Jeon, Y.1
  • 6
    • 33646032364 scopus 로고    scopus 로고
    • Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain
    • Sharma, S., Kulkarni, S. K., Agrewala, J. N. & Chopra, K. Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain. Eur. J. Pharmacol. 536, 256-261 (2006).
    • (2006) Eur. J. Pharmacol. , vol.536 , pp. 256-261
    • Sharma, S.1    Kulkarni, S.K.2    Agrewala, J.N.3    Chopra, K.4
  • 7
    • 84874278883 scopus 로고    scopus 로고
    • The efect of curcumin on oxaliplatin and cisplatin neurotoxicity in rats: Some behavioral, biochemical, and histopathological studies
    • Al Moundhri, M. S., Al-Salam, S., Al Mahrouqee, A., Beegam, S. & Ali, B. H. The efect of curcumin on oxaliplatin and cisplatin neurotoxicity in rats: some behavioral, biochemical, and histopathological studies. J. Med. Toxicol. 9, 25-33 (2013).
    • (2013) J. Med. Toxicol. , vol.9 , pp. 25-33
    • Al Moundhri, M.S.1    Al-Salam, S.2    Al Mahrouqee, A.3    Beegam, S.4    Ali, B.H.5
  • 8
    • 70349501979 scopus 로고    scopus 로고
    • Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: Inhibition of the PKCdelta/JNK/c-Jun pathway
    • Mun, S. H. et al. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. J. Pharmacol. Sci. 111, 13-21 (2009).
    • (2009) J. Pharmacol. Sci. , vol.111 , pp. 13-21
    • Mun, S.H.1
  • 9
    • 33645231857 scopus 로고    scopus 로고
    • Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment
    • Breivik, H., Collett, B., Ventafridda, V., Cohen, R. & Gallacher, D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur. J. Pain. 10, 287-333 (2006).
    • (2006) Eur. J. Pain. , vol.10 , pp. 287-333
    • Breivik, H.1    Collett, B.2    Ventafridda, V.3    Cohen, R.4    Gallacher, D.5
  • 10
    • 34548058841 scopus 로고    scopus 로고
    • Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones diferentially regulate anti-infammatory and anti-proliferative responses through a ROS-independent mechanism
    • Sandur, S. K. et al. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones diferentially regulate anti-infammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis 28, 1765-1773 (2007).
    • (2007) Carcinogenesis , vol.28 , pp. 1765-1773
    • Sandur, S.K.1
  • 11
    • 84911498908 scopus 로고    scopus 로고
    • Curcumin in combined cancer therapy
    • Troselj, K. G. & Kujundzic, R. N. Curcumin in combined cancer therapy. Curr. Pharm. Des. 20, 6682-6696 (2014).
    • (2014) Curr. Pharm. Des. , vol.20 , pp. 6682-6696
    • Troselj, K.G.1    Kujundzic, R.N.2
  • 12
    • 84864657579 scopus 로고    scopus 로고
    • Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells
    • Zhang, Z. J. et al. Curcumin inhibits LPS-induced CCL2 expression via JNK pathway in C6 rat astrocytoma cells. Cell Mol. Neurobiol. 32, 1003-1010 (2012).
    • (2012) Cell Mol. Neurobiol. , vol.32 , pp. 1003-1010
    • Zhang, Z.J.1
  • 13
    • 0032991568 scopus 로고    scopus 로고
    • Curcumin inhibition of infammatory cytokine production by human peripheral blood monocytes and alveolar macrophages
    • Abe, Y., Hashimoto, S. & Horie, T. Curcumin inhibition of infammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol. Res. 39, 41-47 (1999).
    • (1999) Pharmacol. Res. , vol.39 , pp. 41-47
    • Abe, Y.1    Hashimoto, S.2    Horie, T.3
  • 14
    • 0032537814 scopus 로고    scopus 로고
    • Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin
    • Chen, Y. R. & Tan, T. H. Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. Oncogene 17, 173-178 (1998).
    • (1998) Oncogene , vol.17 , pp. 173-178
    • Chen, Y.R.1    Tan, T.H.2
  • 15
    • 28844479049 scopus 로고    scopus 로고
    • Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells
    • Lee, K. W., Kim, J. H., Lee, H. J. & Surh, Y. J. Curcumin inhibits phorbol ester-induced up-regulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast epithelial cells. Antioxid Redox Signal 7, 1612-1620 (2005).
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1612-1620
    • Lee, K.W.1    Kim, J.H.2    Lee, H.J.3    Surh, Y.J.4
  • 16
    • 84857624250 scopus 로고    scopus 로고
    • Curcumin inhibits ox-LDL-induced MCP-1 expression by suppressing the p38MAPK and NF-kappaB pathways in rat vascular smooth muscle cells
    • Zhong, Y., Liu, T. & Guo, Z. Curcumin inhibits ox-LDL-induced MCP-1 expression by suppressing the p38MAPK and NF-kappaB pathways in rat vascular smooth muscle cells. Infamm. Res. 61, 61-67 (2011).
    • (2011) Infamm. Res. , vol.61 , pp. 61-67
    • Zhong, Y.1    Liu, T.2    Guo, Z.3
  • 18
    • 84899094007 scopus 로고    scopus 로고
    • Ligustilide attenuates infammatory pain via inhibition of NFkappaB-mediated chemokines production in spinal astrocytes
    • Zhao, L. X., Jiang, B. C., Wu, X. B., Cao, D. L. & Gao, Y. J. Ligustilide attenuates infammatory pain via inhibition of NFkappaB-mediated chemokines production in spinal astrocytes. Eur. J. Neurosci. 39, 1391-1402 (2014).
    • (2014) Eur. J. Neurosci. , vol.39 , pp. 1391-1402
    • Zhao, L.X.1    Jiang, B.C.2    Wu, X.B.3    Cao, D.L.4    Gao, Y.J.5
  • 19
    • 77649274037 scopus 로고    scopus 로고
    • Chemokines, neuronal-glial interactions, and central processing of neuropathic pain
    • Gao, Y. J. & Ji, R. R. Chemokines, neuronal-glial interactions, and central processing of neuropathic pain. Pharmacol. Ter. 126, 56-68 (2010).
    • (2010) Pharmacol. Ter. , vol.126 , pp. 56-68
    • Gao, Y.J.1    Ji, R.R.2
  • 20
    • 84857236125 scopus 로고    scopus 로고
    • Chemokines and cytokines in neuroinfammation leading to neuropathic pain
    • Kiguchi, N., Kobayashi, Y. & Kishioka, S. Chemokines and cytokines in neuroinfammation leading to neuropathic pain. Curr. Opin. Pharmacol. 12, 55-61 (2012).
    • (2012) Curr. Opin. Pharmacol. , vol.12 , pp. 55-61
    • Kiguchi, N.1    Kobayashi, Y.2    Kishioka, S.3
  • 21
    • 38049150644 scopus 로고    scopus 로고
    • Chemokines and the pathophysiology of neuropathic pain
    • White, F. A., Jung, H. & Miller, R. J. Chemokines and the pathophysiology of neuropathic pain. Proc. Natl. Acad. Sci. USA 104, 20151-20158 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 20151-20158
    • White, F.A.1    Jung, H.2    Miller, R.J.3
  • 22
    • 0035252354 scopus 로고    scopus 로고
    • The role of neuroinfammation and neuroimmune activation in persistent pain
    • DeLeo, J. A. & Yezierski, R. P. The role of neuroinfammation and neuroimmune activation in persistent pain. Pain 90, 1-6 (2001).
    • (2001) Pain , vol.90 , pp. 1-6
    • Deleo, J.A.1    Yezierski, R.P.2
  • 23
    • 57749200564 scopus 로고    scopus 로고
    • Pathological and protective roles of glia in chronic pain
    • Milligan, E. D. & Watkins, L. R. Pathological and protective roles of glia in chronic pain. Nat. Rev. Neurosci. 10, 23-36 (2009).
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 23-36
    • Milligan, E.D.1    Watkins, L.R.2
  • 24
    • 82455192824 scopus 로고    scopus 로고
    • Emerging roles of resolvins in the resolution of infammation and pain
    • Ji, R. R., Xu, Z. Z., Strichartz, G. & Serhan, C. N. Emerging roles of resolvins in the resolution of infammation and pain. Trends Neurosci. 34, 599-609 (2011).
    • (2011) Trends Neurosci. , vol.34 , pp. 599-609
    • Ji, R.R.1    Xu, Z.Z.2    Strichartz, G.3    Serhan, C.N.4
  • 25
    • 63649140837 scopus 로고    scopus 로고
    • Chemokines and pain mechanisms
    • Abbadie, C. et al. Chemokines and pain mechanisms. Brain Res. Rev. 60, 125-134 (2009).
    • (2009) Brain Res. Rev. , vol.60 , pp. 125-134
    • Abbadie, C.1
  • 26
    • 65249114367 scopus 로고    scopus 로고
    • JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain
    • Gao, Y. J. et al. JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J. Neurosci. 29, 4096-4108 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 4096-4108
    • Gao, Y.J.1
  • 27
    • 45849117181 scopus 로고    scopus 로고
    • Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation
    • Zhang, R. X. et al. Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation. Neuroscience 154, 1533-1538 (2008).
    • (2008) Neuroscience , vol.154 , pp. 1533-1538
    • Zhang, R.X.1
  • 28
    • 45549090676 scopus 로고    scopus 로고
    • Cytokine mechanisms of central sensitization: Distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superfcial spinal cord
    • Kawasaki, Y., Zhang, L., Cheng, J. K. & Ji, R. R. Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superfcial spinal cord. J. Neurosci. 28, 5189-5194 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 5189-5194
    • Kawasaki, Y.1    Zhang, L.2    Cheng, J.K.3    Ji, R.R.4
  • 29
    • 0023158864 scopus 로고
    • Evidence that adjuvant arthritis in the rat is associated with chronic pain
    • Colpaert, F. C. Evidence that adjuvant arthritis in the rat is associated with chronic pain. Pain 28, 201-222 (1987).
    • (1987) Pain , vol.28 , pp. 201-222
    • Colpaert, F.C.1
  • 31
    • 34248573424 scopus 로고    scopus 로고
    • Is functional state of spinal microglia involved in the anti-allodynic and anti-hyperalgesic efects of electroacupuncture in rat model of monoarthritis?
    • Shan, S. et al. Is functional state of spinal microglia involved in the anti-allodynic and anti-hyperalgesic efects of electroacupuncture in rat model of monoarthritis? Neurobiol. Dis. 26, 558-568 (2007).
    • (2007) Neurobiol. Dis. , vol.26 , pp. 558-568
    • Shan, S.1
  • 34
    • 0035855860 scopus 로고    scopus 로고
    • Molecular mechanisms of nociception
    • Julius, D. & Basbaum, A. I. Molecular mechanisms of nociception. Nature 413, 203-210 (2001).
    • (2001) Nature , vol.413 , pp. 203-210
    • Julius, D.1    Basbaum, A.I.2
  • 35
    • 0038748399 scopus 로고    scopus 로고
    • Glial proinfammatory cytokines mediate exaggerated pain states: Implications for clinical pain
    • Watkins, L. R., Milligan, E. D. & Maier, S. F. Glial proinfammatory cytokines mediate exaggerated pain states: implications for clinical pain. Adv. Exp. Med. Biol. 521, 1-21 (2003).
    • (2003) Adv. Exp. Med. Biol. , vol.521 , pp. 1-21
    • Watkins, L.R.1    Milligan, E.D.2    Maier, S.F.3
  • 36
    • 77957056575 scopus 로고    scopus 로고
    • Targeting astrocyte signaling for chronic pain
    • Gao, Y. J. & Ji, R. R. Targeting astrocyte signaling for chronic pain. Neurotherapeutics 7, 482-493 (2010).
    • (2010) Neurotherapeutics , vol.7 , pp. 482-493
    • Gao, Y.J.1    Ji, R.R.2
  • 37
    • 75649138334 scopus 로고    scopus 로고
    • Curcumin produces an antihyperalgesic efect via antagonism of TRPV1
    • Yeon, K. Y. et al. Curcumin produces an antihyperalgesic efect via antagonism of TRPV1. J. Dent. Res. 89, 170-174 (2010).
    • (2010) J. Dent. Res. , vol.89 , pp. 170-174
    • Yeon, K.Y.1
  • 38
    • 84855966219 scopus 로고    scopus 로고
    • Curcumin exerts antinociceptive efects in a mouse model of neuropathic pain: Descending monoamine system and opioid receptors are diferentially involved
    • Zhao, X. et al. Curcumin exerts antinociceptive efects in a mouse model of neuropathic pain: descending monoamine system and opioid receptors are diferentially involved. Neuropharmacology 62, 843-854 (2012).
    • (2012) Neuropharmacology , vol.62 , pp. 843-854
    • Zhao, X.1
  • 39
    • 84897381657 scopus 로고    scopus 로고
    • Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model
    • Zhu, X. et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PloS one 9, e91303 (2014).
    • (2014) PloS One , vol.9 , pp. e91303
    • Zhu, X.1
  • 40
    • 84876940937 scopus 로고    scopus 로고
    • Curcumin exerts antinociceptive efects by inhibiting the activation of astrocytes in spinal dorsal horn and the intracellular extracellular signal-regulated kinase signaling pathway in rat model of chronic constriction injury
    • Ji, F. T., Liang, J. J., Liu, L., Cao, M. H. & Li, F. Curcumin exerts antinociceptive efects by inhibiting the activation of astrocytes in spinal dorsal horn and the intracellular extracellular signal-regulated kinase signaling pathway in rat model of chronic constriction injury. Chin Med. J. (Engl.) 126, 1125-1131 (2013).
    • (2013) Chin Med. J. (Engl.) , vol.126 , pp. 1125-1131
    • Ji, F.T.1    Liang, J.J.2    Liu, L.3    Cao, M.H.4    Li, F.5
  • 41
    • 80051788387 scopus 로고    scopus 로고
    • Curcumin and its nano-formulation: The kinetics of tissue distribution and blood-brain barrier penetration
    • Tsai, Y. M., Chien, C. F., Lin, L. C. & Tsai, T. H. Curcumin and its nano-formulation: the kinetics of tissue distribution and blood-brain barrier penetration. Int. J. Pharm. 416, 331-338 (2011).
    • (2011) Int. J. Pharm. , vol.416 , pp. 331-338
    • Tsai, Y.M.1    Chien, C.F.2    Lin, L.C.3    Tsai, T.H.4
  • 42
    • 84874784858 scopus 로고    scopus 로고
    • Curcumin attenuates diabetic neuropathic pain by downregulating TNF-alpha in a rat model
    • Li, Y. et al. Curcumin attenuates diabetic neuropathic pain by downregulating TNF-alpha in a rat model. Int. J. Med. Sci. 10, 377-381 (2013).
    • (2013) Int. J. Med. Sci. , vol.10 , pp. 377-381
    • Li, Y.1
  • 43
    • 84861006262 scopus 로고    scopus 로고
    • Analgesic efects of intrathecal curcumin in the rat formalin test
    • Han, Y. K. et al. Analgesic efects of intrathecal curcumin in the rat formalin test. Korean J. Pain 25, 1-6 (2012).
    • (2012) Korean J. Pain , vol.25 , pp. 1-6
    • Han, Y.K.1
  • 44
    • 84888637560 scopus 로고    scopus 로고
    • Glia and pain: Is chronic pain a gliopathy?
    • Ji, R. R., Berta, T. & Nedergaard, M. Glia and pain: is chronic pain a gliopathy? Pain 154 Suppl 1, S10-28 (2013).
    • (2013) Pain , vol.154 , pp. S10-28
    • Ji, R.R.1    Berta, T.2    Nedergaard, M.3
  • 45
    • 70350196359 scopus 로고    scopus 로고
    • Diferential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain
    • Mika, J. et al. Diferential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain. Eur. J. Pharmacol. 623, 65-72 (2009).
    • (2009) Eur. J. Pharmacol. , vol.623 , pp. 65-72
    • Mika, J.1
  • 46
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • Raghavendra, V., Tanga, F. & DeLeo, J. A. Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J. Pharmacol. Exp. Ter. 306, 624-630 (2003).
    • (2003) J. Pharmacol. Exp. Ter. , vol.306 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    Deleo, J.A.3
  • 47
    • 78651338029 scopus 로고    scopus 로고
    • Light touch induces ERK activation in superfcial dorsal horn neurons afer infammation: Involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia
    • Gao, Y. J. & Ji, R. R. Light touch induces ERK activation in superfcial dorsal horn neurons afer infammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia. J Neurochem. 115, 505-514 (2010).
    • (2010) J Neurochem. , vol.115 , pp. 505-514
    • Gao, Y.J.1    Ji, R.R.2
  • 48
    • 34047266975 scopus 로고    scopus 로고
    • New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis
    • Sun, S. et al. New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis. Pain 129, 64-75 (2007).
    • (2007) Pain , vol.129 , pp. 64-75
    • Sun, S.1
  • 49
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim, G. P. et al. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21, 8370-8377 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 8370-8377
    • Lim, G.P.1
  • 50
    • 84899574914 scopus 로고    scopus 로고
    • Curcumin attenuates acute infammatory injury by inhibiting the TLR4/MyD88/NF-kappaB signaling pathway in experimental traumatic brain injury
    • Zhu, H. T. et al. Curcumin attenuates acute infammatory injury by inhibiting the TLR4/MyD88/NF-kappaB signaling pathway in experimental traumatic brain injury. J. Neuroinfammation 11, 59 (2014).
    • (2014) J. Neuroinfammation , vol.11 , pp. 59
    • Zhu, H.T.1
  • 51
    • 0027157651 scopus 로고
    • Tumor necrosis factor-alpha induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells
    • Hanazawa, S. et al. Tumor necrosis factor-alpha induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells. J. Biol. Chem. 268, 9526-9532 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 9526-9532
    • Hanazawa, S.1
  • 52
    • 84896801592 scopus 로고    scopus 로고
    • Extracellular caspase-6 drives murine infammatory pain via microglial TNF-alpha secretion
    • Berta, T. et al. Extracellular caspase-6 drives murine infammatory pain via microglial TNF-alpha secretion. J. Clin. Invest. 124, 1173-1186 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 1173-1186
    • Berta, T.1
  • 53
    • 27644537034 scopus 로고    scopus 로고
    • Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia
    • Zhang, R. X. et al. Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain 118, 125-136 (2005).
    • (2005) Pain , vol.118 , pp. 125-136
    • Zhang, R.X.1
  • 54
    • 84901640058 scopus 로고    scopus 로고
    • Chemokine (C-C motif) receptor 5 is an important pathological regulator in the development and maintenance of neuropathic pain
    • Matsushita, K. et al. Chemokine (C-C motif) receptor 5 is an important pathological regulator in the development and maintenance of neuropathic pain. Anesthesiology 120, 1491-1503 (2014).
    • (2014) Anesthesiology , vol.120 , pp. 1491-1503
    • Matsushita, K.1
  • 55
    • 0037320840 scopus 로고    scopus 로고
    • Spinal glia and proinfammatory cytokines mediate mirror-image neuropathic pain in rats
    • Milligan, E. D. et al. Spinal glia and proinfammatory cytokines mediate mirror-image neuropathic pain in rats. J. Neurosci. 23, 1026-1040 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 1026-1040
    • Milligan, E.D.1
  • 56
    • 54849416454 scopus 로고    scopus 로고
    • Supraspinal glial-neuronal interactions contribute to descending pain facilitation
    • Wei, F., Guo, W., Zou, S., Ren, K. & Dubner, R. Supraspinal glial-neuronal interactions contribute to descending pain facilitation. J. Neurosci. 28, 10482-10495 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10482-10495
    • Wei, F.1    Guo, W.2    Zou, S.3    Ren, K.4    Dubner, R.5
  • 57
    • 84922697989 scopus 로고    scopus 로고
    • TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-alpha and IL-1beta signaling
    • Lu, Y. et al. TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-alpha and IL-1beta signaling. Pain 155, 2618-2629 (2014).
    • (2014) Pain , vol.155 , pp. 2618-2629
    • Lu, Y.1
  • 58
    • 84925512235 scopus 로고    scopus 로고
    • Curcumin attenuates cfa induced termal hyperalgesia by modulation of antioxidant enzymes and down regulation of TNF-alpha, IL-1beta and IL-6
    • Singh, A. K. & Vinayak, M. Curcumin Attenuates CFA Induced Termal Hyperalgesia by Modulation of Antioxidant Enzymes and Down Regulation of TNF-alpha, IL-1beta and IL-6. Neurochem. Res. 40, 463-472 (2014).
    • (2014) Neurochem. Res. , vol.40 , pp. 463-472
    • Singh, A.K.1    Vinayak, M.2
  • 59
    • 0018956018 scopus 로고
    • Intrathecal morphine in mice: A new technique
    • Hylden, J. L. & Wilcox, G. L. Intrathecal morphine in mice: a new technique. Eur. J. Pharmacol. 67, 313-316 (1980).
    • (1980) Eur. J. Pharmacol. , vol.67 , pp. 313-316
    • Hylden, J.L.1    Wilcox, G.L.2
  • 60
    • 0025860304 scopus 로고
    • Staircase bioassay: The up-and-down method
    • Dixon, W. J. Staircase bioassay: the up-and-down method. Neurosci. Biobehav Rev. 15, 47-50 (1991).
    • (1991) Neurosci. Biobehav Rev. , vol.15 , pp. 47-50
    • Dixon, W.J.1
  • 61
    • 84879695254 scopus 로고    scopus 로고
    • Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinfammation in the spinal cord
    • Hui, J., Zhang, Z. J., Zhang, X., Shen, Y. & Gao, Y. J. Repetitive hyperbaric oxygen treatment attenuates complete Freund's adjuvant-induced pain and reduces glia-mediated neuroinfammation in the spinal cord. J. Pain 14, 747-758 (2013).
    • (2013) J. Pain , vol.14 , pp. 747-758
    • Hui, J.1    Zhang, Z.J.2    Zhang, X.3    Shen, Y.4    Gao, Y.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.