Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy

Journal of Molecular and Cellular Cardiology

Volumn 84, Issue , 2015, Pages 202-211

  Thoonen, Robrecht ^a   Ernande, Laura ^a,b   Cheng, Juan ^a,c   Nagasaka, Yasuko ^a   Yao, Vincent ^a   Miranda Bezerra, Alexandre ^a   Chen, Chan ^a   Chao, Wei ^a   Panagia, Marcello ^a   Sosnovik, David E ^a   Puppala, Dheeraj ^a   Armoundas, Antonis A ^a   Hindle, Allyson ^a   Bloch, Kenneth D ^a   Buys, Emmanuel S ^a   Scherrer Crosbie, Marielle ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b INSERM   (France)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Brown adipose tissue; Cardioprotection; Heart failure; Isoproterenol; Uncoupling protein 1

Indexed keywords

CATECHOLAMINE; ISOPRENALINE; TROPONIN I; UNCOUPLING PROTEIN 1; BIOLOGICAL MARKER; CARDIOTONIC AGENT; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; UCP1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART MUSCLE INJURY; HEART PROTECTION; HEART VENTRICLE REMODELING; ISCHEMIC CARDIOMYOPATHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SURVIVAL; ANIMAL; BLOOD PRESSURE; BODY WEIGHT; C57BL MOUSE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CARDIOMYOPATHY; CHEMICALLY INDUCED; COMPLICATION; DEFICIENCY; DIAGNOSTIC IMAGING; DRUG EFFECTS; ECHOGRAPHY; ENZYMOLOGY; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; HEART FAILURE; HEART VENTRICLE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TRANSPLANTATION;

MUS;

ADIPOSE TISSUE, BROWN; ANIMALS; BIOMARKERS; BLOOD PRESSURE; BODY WEIGHT; CARDIOMYOPATHIES; CARDIOTONIC AGENTS; CATECHOLAMINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROSIS; GENE EXPRESSION REGULATION; HEART FAILURE; HEART VENTRICLES; ION CHANNELS; ISOPROTERENOL; MALE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; ULTRASONOGRAPHY; UNCOUPLING PROTEIN 1; VENTRICULAR REMODELING;

EID: 84930201353     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.05.002     Document Type: Article

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