Autoregulation of inducible nitric oxide synthase expression by RNA interference provides neuroprotection in neonatal rats

Theranostics

Volumn 5, Issue 5, 2015, Pages 504-514

  Wang, Zhi ^a,b   Feng, Chenzhuo ^a,c   Zhao, Huijuan ^a   Ren, Xiaoyan ^a   Peng, Shuling ^b   Zuo, Zhiyi ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c HANGZHOU NORMAL UNIVERSITY   (China)

Author keywords

Autoregulation of gene expression; Inducible nitric oxide synthase; Neonate; Neuroprotection; Rats

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; LENTIVIRUS VECTOR; SHORT HAIRPIN RNA; NEUROPROTECTIVE AGENT; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; BRAIN INJURY; CONTROLLED STUDY; CYTOMEGALOVIRUS; FEMALE; FUNCTIONAL DISEASE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IN VIVO STUDY; MALE; NEUROPROTECTION; NEWBORN; NONHUMAN; PROMOTER REGION; RAT; RNA INTERFERENCE; ANIMAL; BIOSYNTHESIS; COMPLICATION; DRUG EFFECTS; GENETICS; HYPOXIA, BRAIN; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ANIMALS; ANIMALS, NEWBORN; FEMALE; GENE EXPRESSION REGULATION; HYPOXIA, BRAIN; HYPOXIA-ISCHEMIA, BRAIN; MALE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; RNA, SMALL INTERFERING; TREATMENT OUTCOME;

EID: 84930195948     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.10441     Document Type: Article

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