Perioperative aspirin improves neurological outcome after focal brain ischemia possibly via inhibition of Notch 1 in rat

Journal of Neuroinflammation

Volumn 11, Issue , 2014, Pages

  Wang, Zhongxing ^a,b   Huang, Wenqi ^b   Zuo, Zhiyi ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Aspirin; Brain ischemia; Inflammatory cytokines; Notch

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CELL PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; IONIZED CALCIUM BINDING ADAPTER MOLECULE 1; N [N (3,5 DIFLUOROPHENACETYL) LEVO ALANYL]PHENYLGLYCINE TERT BUTYL ESTER; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG; DIPEPTIDE; ENZYME INHIBITOR; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG MECHANISM; MALE; MICROGLIA; NERVE CELL INHIBITION; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; NOTCH INTRACELLULAR DOMAIN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; ANALYSIS OF VARIANCE; ANIMAL; CEREBRAL ARTERY DISEASE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; NERVOUS SYSTEM DISEASES; PSYCHOMOTOR PERFORMANCE; SPRAGUE DAWLEY RAT; TIME;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BRAIN INFARCTION; DIPEPTIDES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; NERVOUS SYSTEM DISEASES; PSYCHOMOTOR PERFORMANCE; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84897446149     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-56     Document Type: Article

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