Atorvastatin prevents angiotensin II-induced high permeability of human arterial endothelial cell monolayers via ROCK signaling pathway

Biochemical and Biophysical Research Communications

Volumn 459, Issue 1, 2015, Pages 94-99

  Yi, Ren ^a   Xiao Ping, Gao ^a   Hui, Liang ^a  

^a People's Hospital of Hunan Province   (China)

Author keywords

Aneurysm; Atorvastatin; Cell permeability; ROCK signaling pathway; ROCK II; Tight junctions

Indexed keywords

ANGIOTENSIN II; ATORVASTATIN; LIM KINASE 1; MYOSIN LIGHT CHAIN 2; PROTEIN; PROTEIN MYPT1; PROTEIN SERINE THREONINE KINASE; PROTEIN ZO1; RHO KINASE II; RHO KINASE INHIBITOR; UNCLASSIFIED DRUG; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2-METHYL-1-((4-METHYL-5-ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; HEPTANOIC ACID DERIVATIVE; LIM KINASE; LIMK1 PROTEIN, HUMAN; PYRROLE DERIVATIVE; RHO KINASE; TJP1 PROTEIN, HUMAN;

ARTERY ENDOTHELIUM; ARTICLE; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; ARTERY; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; PERMEABILITY; PHOSPHORYLATION; VASCULAR ENDOTHELIUM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANGIOTENSIN II; ARTERIES; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HEPTANOIC ACIDS; HUMANS; LIM KINASES; PERMEABILITY; PHOSPHORYLATION; PYRROLES; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84930177268     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.02.076     Document Type: Article

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