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Volumn 68, Issue 23, 2008, Pages 9754-9762

TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIMETHYL 5 (2 OXO 1H INDOL 3 YLMETHYLENE) 3 PYRROLEPROPIONIC ACID; CHEMOKINE; CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; FIBROBLAST GROWTH FACTOR RECEPTOR 1; INTERLEUKIN 12P40; MESSENGER RNA; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; VASCULOTROPIN RECEPTOR 2;

EID: 57149106131     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1748     Document Type: Article
Times cited : (88)

References (45)
  • 1
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 2
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 3
    • 0023157363 scopus 로고
    • Angiogenic factors
    • Folkman J, Klagsbrun M. Angiogenic factors. Science 1987;235:442-7.
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 4
    • 33744466541 scopus 로고    scopus 로고
    • Antiangiogenic therapy: A universal chemosensitization strategy for cancer?
    • Kerbel RS. Antiangiogenic therapy: a universal chemosensitization strategy for cancer? Science 2006;312:1171-5.
    • (2006) Science , vol.312 , pp. 1171-1175
    • Kerbel, R.S.1
  • 5
    • 0034655182 scopus 로고    scopus 로고
    • PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
    • Wood JM, Bold G, Buchdunger E, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 2000;60:2178-89.
    • (2000) Cancer Res , vol.60 , pp. 2178-2189
    • Wood, J.M.1    Bold, G.2    Buchdunger, E.3
  • 6
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta LG, Chen H, O'Connor SJ, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997;57:4593-9.
    • (1997) Cancer Res , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3
  • 7
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307:58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 8
    • 0031870832 scopus 로고    scopus 로고
    • Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy
    • Witte L, Hicklin DJ, Zhu Z, et al. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy. Cancer Metastasis Rev 1998;17:155-61.
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 155-161
    • Witte, L.1    Hicklin, D.J.2    Zhu, Z.3
  • 9
    • 0027421333 scopus 로고
    • Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
    • Kendall RL, Thomas KA. Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci U S A 1993;90:10705-9.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 10705-10709
    • Kendall, R.L.1    Thomas, K.A.2
  • 10
    • 0032893263 scopus 로고    scopus 로고
    • SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
    • Fong TA, Shawver LK, Sun L, et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 1999;59:99-106.
    • (1999) Cancer Res , vol.59 , pp. 99-106
    • Fong, T.A.1    Shawver, L.K.2    Sun, L.3
  • 11
    • 0036490442 scopus 로고    scopus 로고
    • Smart drugs: Tyrosine kinase inhibitors in cancer therapy
    • Shawver LK, Slamon D, Ullrich A. Smart drugs: tyrosine kinase inhibitors in cancer therapy. Cancer Cell 2002;1:117-23.
    • (2002) Cancer Cell , vol.1 , pp. 117-123
    • Shawver, L.K.1    Slamon, D.2    Ullrich, A.3
  • 12
    • 0033883776 scopus 로고    scopus 로고
    • SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
    • Laird AD, Vajkoczy P, Shawver LK, et al. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 2000;60:4152-60.
    • (2000) Cancer Res , vol.60 , pp. 4152-4160
    • Laird, A.D.1    Vajkoczy, P.2    Shawver, L.K.3
  • 13
    • 0035866334 scopus 로고    scopus 로고
    • Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms
    • Shaheen RM, Tseng WW, Davis DW, et al. Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms. Cancer Res 2001;61:1464-8.
    • (2001) Cancer Res , vol.61 , pp. 1464-1468
    • Shaheen, R.M.1    Tseng, W.W.2    Davis, D.W.3
  • 14
    • 0033231069 scopus 로고    scopus 로고
    • Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
    • Shaheen RM, Davis DW, Liu W, et al. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res 1999;59:5412-6.
    • (1999) Cancer Res , vol.59 , pp. 5412-5416
    • Shaheen, R.M.1    Davis, D.W.2    Liu, W.3
  • 15
    • 24644457216 scopus 로고    scopus 로고
    • TSU-68 (SU6668) inhibits local tumor growth and liver metastasis of human colon cancer xenografts via anti-angiogenesis
    • Yorozuya K, Kubota T, Watanabe M, et al. TSU-68 (SU6668) inhibits local tumor growth and liver metastasis of human colon cancer xenografts via anti-angiogenesis. Oncol Rep 2005;14:677-82.
    • (2005) Oncol Rep , vol.14 , pp. 677-682
    • Yorozuya, K.1    Kubota, T.2    Watanabe, M.3
  • 16
    • 0036990103 scopus 로고    scopus 로고
    • The organ microenvironment and cancer metastasis
    • Fidler IJ. The organ microenvironment and cancer metastasis. Differentiation 2002;70:498-505.
    • (2002) Differentiation , vol.70 , pp. 498-505
    • Fidler, I.J.1
  • 17
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-6.
    • (2001) Nature , vol.410 , pp. 50-56
    • Muller, A.1    Homey, B.2    Soto, H.3
  • 18
    • 0038206771 scopus 로고    scopus 로고
    • The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases
    • Phillips RJ, Burdick MD, Lutz M, Belperio JA, Keane MP, Strieter RM. The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. Am J Respir Crit Care Med 2003;167:1676-86.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1676-1686
    • Phillips, R.J.1    Burdick, M.D.2    Lutz, M.3    Belperio, J.A.4    Keane, M.P.5    Strieter, R.M.6
  • 19
    • 33751319000 scopus 로고    scopus 로고
    • Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
    • Pan J, Mestas J, Burdick MD, et al. Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer 2006;5:56.
    • (2006) Mol Cancer , vol.5 , pp. 56
    • Pan, J.1    Mestas, J.2    Burdick, M.D.3
  • 20
    • 34447524931 scopus 로고    scopus 로고
    • Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes
    • Kawada K, Hosogi H, Sonoshita M, et al. Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes. Oncogene 2007;26:4679-88.
    • (2007) Oncogene , vol.26 , pp. 4679-4688
    • Kawada, K.1    Hosogi, H.2    Sonoshita, M.3
  • 21
    • 0036782035 scopus 로고    scopus 로고
    • MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
    • Hiratsuka S, Nakamura K, Iwai S, et al. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2002;2:289-300.
    • (2002) Cancer Cell , vol.2 , pp. 289-300
    • Hiratsuka, S.1    Nakamura, K.2    Iwai, S.3
  • 22
    • 33751504690 scopus 로고    scopus 로고
    • Tumour-mediated up-regulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
    • Hiratsuka S, Watanabe A, Aburatani H, Maru Y. Tumour-mediated up-regulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 2006;8:1369-75.
    • (2006) Nat Cell Biol , vol.8 , pp. 1369-1375
    • Hiratsuka, S.1    Watanabe, A.2    Aburatani, H.3    Maru, Y.4
  • 23
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005;438:820-7.
    • (2005) Nature , vol.438 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3
  • 24
    • 0038735778 scopus 로고    scopus 로고
    • Orthotopic implantation of a colon cancer xenograft induces high expression of cyclooxygenase-2
    • Shoji T, Konno H, Tanaka T, et al. Orthotopic implantation of a colon cancer xenograft induces high expression of cyclooxygenase-2. Cancer Lett 2003;195:235-41.
    • (2003) Cancer Lett , vol.195 , pp. 235-241
    • Shoji, T.1    Konno, H.2    Tanaka, T.3
  • 25
    • 0028868220 scopus 로고
    • Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470
    • Tanaka T, Konno H, Matsuda I, Nakamura S, Baba S. Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470. Cancer Res 1995;55:836-9.
    • (1995) Cancer Res , vol.55 , pp. 836-839
    • Tanaka, T.1    Konno, H.2    Matsuda, I.3    Nakamura, S.4    Baba, S.5
  • 26
    • 0028901328 scopus 로고
    • Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP-470, and mitomycin C on the growth and liver metastasis of human colon cancer
    • Konno H, Tanaka T, Matsuda I, et al. Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP-470, and mitomycin C on the growth and liver metastasis of human colon cancer. Int J Cancer 1995;61:268-71.
    • (1995) Int J Cancer , vol.61 , pp. 268-271
    • Konno, H.1    Tanaka, T.2    Matsuda, I.3
  • 27
    • 0029964403 scopus 로고    scopus 로고
    • Efficacy of an angiogenesis inhibitor, TNP-470, in xenotransplanted human colorectal cancer with high metastatic potential
    • Konno H, Tanaka T, Kanai T, Maruyama K, Nakamura S, Baba S. Efficacy of an angiogenesis inhibitor, TNP-470, in xenotransplanted human colorectal cancer with high metastatic potential. Cancer 1996;77:1736-40.
    • (1996) Cancer , vol.77 , pp. 1736-1740
    • Konno, H.1    Tanaka, T.2    Kanai, T.3    Maruyama, K.4    Nakamura, S.5    Baba, S.6
  • 28
    • 0032779969 scopus 로고    scopus 로고
    • Antitumor effect on human gastric cancer and induction of apoptosis by vascular endothelial growth factor neutralizing antibody
    • Kamiya K, Konno H, Tanaka T, et al. Antitumor effect on human gastric cancer and induction of apoptosis by vascular endothelial growth factor neutralizing antibody. Jpn J Cancer Res 1999;90:794-800.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 794-800
    • Kamiya, K.1    Konno, H.2    Tanaka, T.3
  • 29
    • 0035112437 scopus 로고    scopus 로고
    • Prevention of hepatic and peritoneal metastases by the angiogenesis inhibitor fr-118487 after removal of growing tumor in mice
    • Tanaka T, Konno H, Baba S, et al. Prevention of hepatic and peritoneal metastases by the angiogenesis inhibitor fr-118487 after removal of growing tumor in mice. Jpn J Cancer Res 2001;92:88-94.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 88-94
    • Tanaka, T.1    Konno, H.2    Baba, S.3
  • 30
    • 34548088313 scopus 로고    scopus 로고
    • ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells
    • Kikuchi H, Uchida C, Hattori T, et al. ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells. Carcinogenesis 2007;28:1752-8.
    • (2007) Carcinogenesis , vol.28 , pp. 1752-1758
    • Kikuchi, H.1    Uchida, C.2    Hattori, T.3
  • 31
    • 45949108191 scopus 로고    scopus 로고
    • An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition
    • Nomellini V, Faunce DE, Gomez CR, Kovacs EJ. An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition. J Leukoc Biol 2008;83:1493-501.
    • (2008) J Leukoc Biol , vol.83 , pp. 1493-1501
    • Nomellini, V.1    Faunce, D.E.2    Gomez, C.R.3    Kovacs, E.J.4
  • 33
    • 33746051169 scopus 로고    scopus 로고
    • Chemokines, chemokine receptors, and cancer metastasis
    • Kakinuma T, Hwang ST. Chemokines, chemokine receptors, and cancer metastasis. J Leukoc Biol 2006;79:639-51.
    • (2006) J Leukoc Biol , vol.79 , pp. 639-651
    • Kakinuma, T.1    Hwang, S.T.2
  • 35
    • 33644830150 scopus 로고    scopus 로고
    • The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects
    • Shimozato O, Ugai S, Chiyo M, et al. The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects. Immunology 2006;117:22-8.
    • (2006) Immunology , vol.117 , pp. 22-28
    • Shimozato, O.1    Ugai, S.2    Chiyo, M.3
  • 36
    • 0035896521 scopus 로고    scopus 로고
    • Induction of nitric-oxide synthase and activation of NF-κB by interleukin-12 p40 in microglial cells
    • Pahan K, Sheikh FG, Liu X, Hilger S, McKinney M, Petro TM. Induction of nitric-oxide synthase and activation of NF-κB by interleukin-12 p40 in microglial cells. J Biol Chem 2001;276:7899-905.
    • (2001) J Biol Chem , vol.276 , pp. 7899-7905
    • Pahan, K.1    Sheikh, F.G.2    Liu, X.3    Hilger, S.4    McKinney, M.5    Petro, T.M.6
  • 37
    • 0028783404 scopus 로고
    • HMGI(Y) and Sp1 in addition to NF-κB regulate transcription of the MGSA/GROα gene
    • Wood LD, Farmer AA, Richmond A. HMGI(Y) and Sp1 in addition to NF-κB regulate transcription of the MGSA/GROα gene. Nucleic Acids Res 1995;23:4210-9.
    • (1995) Nucleic Acids Res , vol.23 , pp. 4210-4219
    • Wood, L.D.1    Farmer, A.A.2    Richmond, A.3
  • 38
    • 0024708518 scopus 로고
    • The distribution of secondary growths in cancer of the breast. 1889
    • Paget S. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Rev 1989;8:98-101.
    • (1989) Cancer Metastasis Rev , vol.8 , pp. 98-101
    • Paget, S.1
  • 39
    • 0030969422 scopus 로고    scopus 로고
    • Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique
    • Greene GF, Kitadai Y, Pettaway CA, von Eschenbach AC, Bucana CD, Fidler IJ. Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique. Am J Pathol 1997;150:1571-82.
    • (1997) Am J Pathol , vol.150 , pp. 1571-1582
    • Greene, G.F.1    Kitadai, Y.2    Pettaway, C.A.3    von Eschenbach, A.C.4    Bucana, C.D.5    Fidler, I.J.6
  • 40
    • 0036659130 scopus 로고    scopus 로고
    • Role of CXCL1 in tumorigenesis of melanoma
    • Dhawan P, Richmond A. Role of CXCL1 in tumorigenesis of melanoma. J Leukoc Biol 2002;72:9-18.
    • (2002) J Leukoc Biol , vol.72 , pp. 9-18
    • Dhawan, P.1    Richmond, A.2
  • 41
    • 0028268514 scopus 로고
    • Acute inflammatory activity of the S100 protein CP-10. Activation of neutrophils in vivo and in vitro
    • Devery JM, King NJ, Geczy CL. Acute inflammatory activity of the S100 protein CP-10. Activation of neutrophils in vivo and in vitro. J Immunol 1994;152:1888-97.
    • (1994) J Immunol , vol.152 , pp. 1888-1897
    • Devery, J.M.1    King, N.J.2    Geczy, C.L.3
  • 42
    • 0037049884 scopus 로고    scopus 로고
    • Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166
    • Oba K, Konno H, Tanaka T, et al. Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166. Cancer Lett 2002;175:45-51.
    • (2002) Cancer Lett , vol.175 , pp. 45-51
    • Oba, K.1    Konno, H.2    Tanaka, T.3
  • 43
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
    • Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 2001;7:987-9.
    • (2001) Nat Med , vol.7 , pp. 987-989
    • Jain, R.K.1
  • 44
    • 34047260282 scopus 로고    scopus 로고
    • Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: Insights from a mathematical model
    • Jain RK, Tong RT, Munn LL. Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res 2007;67:2729-35.
    • (2007) Cancer Res , vol.67 , pp. 2729-2735
    • Jain, R.K.1    Tong, R.T.2    Munn, L.L.3
  • 45
    • 38149006909 scopus 로고    scopus 로고
    • Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis
    • Gao D, Nolan DJ, Mellick AS, Bambino K, McDonnell K, Mittal V. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science 2008;319:195-8.
    • (2008) Science , vol.319 , pp. 195-198
    • Gao, D.1    Nolan, D.J.2    Mellick, A.S.3    Bambino, K.4    McDonnell, K.5    Mittal, V.6


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