Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure

Brain Research

Volumn 1613, Issue , 2015, Pages 27-36

  Jacob, Aude ^a,b   Potin, Sophie ^a,b   Chapy, Hélène ^a,b   Crete, Dominique ^a,b   Glacial, Fabienne ^b,c,d   Ganeshamoorthy, Kayathiri ^b,c,d   Couraud, Pierre Olivier ^b,c,d   Scherrmann, Jean Michel ^a,b   Declèves, Xavier ^a,b  

^a UMR S 1144   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c INSTITUT COCHIN   (France)

^d CNRS   (France)

Author keywords

Aryl hydrocarbon receptor; ATP binding cassette transporters; Blood brain barrier; CYP1B1; hCMEC D3

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; BREAST CANCER RESISTANCE PROTEIN; CYTOCHROME P450 1B1; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; SMALL INTERFERING RNA; ABC TRANSPORTER; ABCB1 PROTEIN, HUMAN; ABCG2 PROTEIN, HUMAN; CYP1B1 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN; TUMOR PROTEIN;

ARTICLE; BRAIN CAPILLARY ENDOTHELIAL CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPOSURE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROVASCULATURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; BRAIN CORTEX; CELL LINE; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; SIGNAL TRANSDUCTION; VASCULARIZATION;

ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CEREBRAL CORTEX; CYTOCHROME P-450 CYP1B1; ENDOTHELIAL CELLS; HUMANS; MICROVESSELS; NEOPLASM PROTEINS; P-GLYCOPROTEINS; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; TETRACHLORODIBENZODIOXIN;

EID: 84930085136     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.03.049     Document Type: Article

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