2,3,7,8-Tetrachlorodibenzo-p-dioxin increases reactive oxygen species production in human endothelial cells via induction of cytochrome P4501A1

Toxicology and Applied Pharmacology

Volumn 245, Issue 1, 2010, Pages 91-99

  Kopf, P G ^a   Walker, M K ^a,b,c  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

Aryl hydrocarbon receptor; Cytochrome P4501A1; Endothelial cells; Nitric oxide; Reactive oxygen species; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DICHLORODIHYDROFLUORESCEIN DIACETATE; HYDROETHIDINE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MESSENGER RNA; NITRIC OXIDE; OXIDIZING AGENT; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SUPEROXIDE;

AORTA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME SYNTHESIS; FLUORESCENCE ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LONG TERM EXPOSURE;

ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A1; ENDOTHELIAL CELLS; ENZYME INDUCTION; HUMANS; NITROGEN OXIDES; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

MUS;

EID: 77952545031     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.02.007     Document Type: Article

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