Involvement of aryl hydrocarbon receptor in basal and 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced expression of target genes in primary human hepatocytes

Toxicology in Vitro

Volumn 24, Issue 6, 2010, Pages 1775-1781

  Le Vee, Marc ^a   Jouan, Elodie ^a   Fardel, Olivier ^a,b  

^a UNIVERSITÉ DE RENNES 1   (France)

^b PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; Aryl hydrocarbon receptor; Primary human hepatocytes; Small interfering RNAs; Target genes

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 3A1; AROMATIC HYDROCARBON RECEPTOR; CARRIER PROTEIN; CELL PROTEIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; DIMETHYL SULFOXIDE; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR B; MESSENGER RNA; MYOFERLIN; PENTOXYRESORUFIN DEALKYLASE; SMALL INTERFERING RNA; SOLUTE CARRIER TRANSPORTER 7A5; UNCLASSIFIED DRUG;

ALDH3A1 GENE; ARTICLE; CELL STRAIN HEPARG; CONTROLLED STUDY; CYP1A1 GENE; CYP1A2 GENE; CYP1B1 GENE; ENZYME ACTIVITY; FER1L3 GENE; GENE; GENE CONTROL; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IL17RB GENE; LIVER CELL; SLC7A5 GENE;

CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HEPATOCYTES; HUMANS; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; RNA, SMALL INTERFERING; TETRACHLORODIBENZODIOXIN; TRANSFECTION;

EID: 77956170997     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.07.001     Document Type: Article

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