N-Glycosylation of a mouse IgG expressed in transgenic tobacco plants

Glycobiology

Volumn 9, Issue 4, 1999, Pages 365-372

  Cabanes Macheteau, Marion ^c   Fitchette Lainé, Anne Catherine ^c   Loutelier Bourhis, Corinne ^a   Lange, Catherine ^a   Vine, Nick D ^b   Ma, Julian K C ^b   Lerouge, Patrice ^c   Faye, Loïc ^c  

^a UNIVERSITÉ DE ROUEN   (France)

^b GUY S HOSPITAL   (United Kingdom)

^c NONE

Author keywords

Monoclonal antibody; N glycosylation; Transgenic plants

Indexed keywords

GLYCAN; GLYCOPROTEIN; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; OLIGOSACCHARIDE; RECOMBINANT PROTEIN;

ARTICLE; GENE EXPRESSION SYSTEM; GLYCOSYLATION; IMMUNOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; TOBACCO; TRANSGENIC PLANT;

MAMMALIA; MURINAE; NICOTIANA OBTUSIFOLIA; NICOTIANA TABACUM;

EID: 0032931237     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/9.4.365     Document Type: Article

References (30)

1. Anumula, K.R. and Taylor, P.B. (1991) Rapid characterization of asparagine-linked oligosaccharides isolated from glycoproteins using a carbohydrate analyser. Eur. J. Biochem., 195, 269-280.
2. During, K., Hippe, S., Kreuzaler, F. and Schell, J. (1990) Synthesis and self-assembly of a functional monoclonal antibody in transgenic Nicotiana tabacum. Plant Mol. Biol., 15, 281-293.
3. Faye, L. and Chrispeels, M.J. (1985) Characterization of N-linked oligosaccharides by affinoblotting with concanavalin A-peroxidase and treatment of the blots with glycosidases. Anal. Biochem., 149, 218-224.
4. Faye, L., Gomord, V., Fitchette-Lainé, A-C. and Chrispeels, M.J. (1993) Affinity purification of antibodies specific for Asn-linked glycans containing α 1-3 fucose or β 1-2 xylose. Anal. Biochem., 109, 104-108.
5. Fitchette-Lainé, A-C., Gomord, V., Cabanes, M., Saint Macary, M., Foucher, B., Michalski, J-C., Hawes, C., Lerouge, P. and Faye, L. (1997) N-Glycans harboring the Lewis a epitope are expressed at the surface of plant cells. Plant. J., 12, 1411-1417.
6. Fitchette-Lainé, A-C., Denmat, L-A., Lerouge, P. and Faye, L. (1998) Analysis of N-and O-glycosylation of plant proteins. Methods Biotechnol., 3, 271-290.
7. Hase, S., Ibuki, T. and Ikenaka, T. (1984) Reexamination of the pyridylamination used for fluorescence labeling of oligosaccharides and its application to glycoproteins. J. Biochem., 95, 197-203.
8. Hardy, M.R. (1989) Monosaccharide analysis of glycoconjugates by high-performance anion-exchange chromatography with pulsed amperometric detection. Methods Enzymol., 179, 76-82.
9. Hiatt, A.C., Cafferkey, R. and Bowdish, K. (1989) Production of antibodies in transgenic plants. Nature, 342, 76-78.
10. Jefferis, R. and Lund, J. (1997) Glycosylation of antibody molecules: structural and functional significance. Antibody Eng. Chem. Immnnol., 65, 111-128.
11. Lerouge, P., Cabanes-Macheteau, M., Rayon, C., Fitchette-Lainé, A-C., Gomord, V. and Faye, L. (1998) N-Glycoprotein biosynthesis in plants: Recent developments and future trends. Plant Mol. Biol., 38, 31-48.
12. Ma, J.K.-C. and Hein, M.B. (1995) Immunotherapeutic potential of antibodies produced in plants. Trends Biotechnol., 13, 522-527.
13. Ma, J.K.-C., Hunjan, M., Smith, R. Kelly, C. and Lehner, T. (1990) An investigation into the mechanism of protection by local passive immunisation with monoclonal antibodies against Streptococcus mutans. Infect Immunol., 58, 3407-3414.
14. Ma, J.K.-C., Lehner, T., Stabila, P., Fux, C.I. and Hiatt, A. (1994) Assembly of monoclonal antibodies with IgG1 and IgA heavy chain domains in transgenic tobacco plants. Eur. J. Immunol., 24, 131-138.
15. MaJ, K.-C., Hiatt, A., Hein, M.B., Vine, N.D., Wang, F., Stabila, P., van Dolleweerd, C., Mostov, K. and Lehner, T. (1995) Generation and assembly of secretory antibodies in plants. Science, 268, 716-719.
16. a carbohydrate motif in a secretory peroxidase from a plant cell suspension culture (Vaccinium myrtillus L.). FEBS Lett., 415, 186-191.
17. Mizuochi, T., Hamako, J. and Titani, K. (1987) Structure of the sugar chains of mouse immunoglobulin G. Arch. Biochem. Biophys., 257, 387-394.
18. Moffat, A.S. (1995) Exploring transgenic plants as a new vaccine source. Science, 268, 658-660.
19. Montreuil, J., Bouquelet, S., Debray, H., Foumet, B., Spik, G. and Strecker, G. (1986) Carbohydrate analysis: a pratical approach. In Chaplin, M.F. and Kennedy, J.F (eds), Carbohydrate Analysis: A Practical Approach., IRL Press, Oxford, pp. 143-204
20. Owen, M.R.L. and Pen, J. (1996) Transgenic Plants: A Production System for Industrial and Pharmaceutical Proteins. John Wiley and Sons, Chichester.
21. Parekh, R.B., Dwek, R.A., Sutton, B.J., Fernandes, D.L., Leung, A., Stanworth, D., Rademacher, T.W., Mizuochi, T., Taniguchi, T., Matsuta, K., Takeuchi, F., Nagano, Y., Miyamoto, T. and Kobata, A. (1985) Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG. Nature, 316, 452-457.
22. Rademacher, T.W., Homans, S.W., Parekh, R.B. and Dwek, R.A. (1986) Immunoglobulin G as glycoprotein. Biochem. Soc. Symp., 51, 131-148.
23. Rayon, C., Gomord, V., Faye, L. and Lerouge, P. (1996) N-Glycosylation of phytohemagglutinin expressed in bean cotyledons or in transgenic tobacco plants. Plant Physiol. Biochem., 34, 273-281.
24. Rohrer, J., Thayer, J., Avdalovic, N. and Weitzhandler, M. (1995) HPAEC-PAD analysis of monoclonal antibodiy glycosylation. Techniques Protein Chem., 6, 65-73.
25. Rothman, R.J., Warren, L., Vliegenthart, J.F.G. and Hard, K.J. (1989) Clonal analysis of the glycosylation of immunoglobulin G secreted by murine hybridomas. Biochemistry, 28, 1377-1384.
26. Smith, R. and Lehner, T. (1989) Characterisation of monoclonal antibodies to common protein epitopes on the cell surface of Streptococcus sobrinus. Oral Microbiol. Immunol., 4, 153-158.
27. Takahashi, N., Ishii, I., Ishihara, H., Mori, M., Tejima, S., Jefferis, R., Endo, S. and Arata, Y. (1987) Comparative structural study of the N-linked oligosaccharides of human normal and pathological immunoglobulin G. Biochemistry, 26, 1137-1144.
28. Tomiya, N., Kurono, M., Ishihara, H., Tejima, S., Endo, S., Arata, Y. and Takahashi, N. (1987) Structural analysis of N-linked oligosaccharides by a combination of glycopeptidase, exoglycosidases, and high-performance liquid chromatography. Anal. Biochem., 163, 489-499.
29. Tomiya, N., Awaya, J., Kurono, M., Endo, S., Arata, Y. and Takahashi, N. (1988) Analyses of N-linked oligosaccharides using a two-dimensional mapping technique. Anal. Biochem., 171, 73-90.
30. Wright, A. and Morrison, S.L. (1997) Effect of glycosylation on antibody function: implications for genetic engineering. Trends Biotechnol., 15, 26-32.